The invention relates to a grid line loss monitoring and analyzing system, which utilizes data in an electric power automation system to perform real-time monitoring and analysis on grid line loss. The system comprises a data acquisition server, a database and an application server, wherein the data of the electric power automation system is connected with the data acquisition server through an FTP server and a data access interface; the data acquisition server comprises a data acquisition module and a line loss computation module; the database comprises an EMS data sheet module, a TMR data sheet module, a meteorological data sheet module and a line loss sheet module; and the application server comprises a basic data management module, an actual line loss analysis module, a theoretical line loss analysis module, a line loss comparative analysis module, a line loss statistical report module, a system configuration module, a user management module and a wiring diagram navigation module. By utilizing the conventional electric power automation system effectively, the line loss management level and working efficiency are improved, and a scientific basis is provided for the formulation and implementation of loss reduction measures.