The invention discloses an enterprise economic management information security system, which includes a registration module, a man-machine operation module, an identity authentication module, a central processing unit, a data processing module, an enterprise economic management information database, a virus feature database, a regular inspection module, a virus Feature matching module, system anomaly evaluation module, data isolation upload module and data analysis module. The present invention integrates voiceprint verification and palm vein verification, which greatly improves the security of information. At the same time, it has a virus scanning function. Once an intrusion is found, the system has a data protection and clearing function, which further ensures the security of electronic file information. Each data entry carries the identity information of the person who entered it, which realizes the traceability of the data, and has its own data analysis and statistics function, which provides a basis for enterprise economic management decision-making.