The invention belongs to the technical field of chemical engineering, more specifically relates to an epoxy/organosilicon/inorganic nano-hybrid material and a preparation method thereof. The epoxy/organosilicon/inorganic nano-hybrid material is made from epoxy resin, organosilicon resin, acidic inorganic nano-particles, unnecessary organic epoxy silane, an unnecessary adjuvant and the like. The components are hybridized and cured in situ under catalytic action of the inorganic nano-particles by simple physical mixing to obtain the epoxy/organosilicon/inorganic nano-hybrid material. The production and preparation processes are environment-friendly, energy-saving, simple and easy for control, and no solvent is used in the processes. The epoxy/organosilicon/inorganic nano-hybrid material prepared by the method has the characteristics of good bonding property, high mechanical strength, high shear strength and excellent machinability of the epoxy resin, and has the characteristics of strong heat resistance, good insulatibity, strong elasticity, strong ageing resistance and good transparence of the organosilicon resin. The epoxy/organosilicon/inorganic nano-hybrid material can be taken as an adhesive, an insulating material, printing ink, a coating material, a solder mask material of a printed circuit, an optical protection material, an LED encapsulation material, an optoelectronic conversion material and the like.