Sticky high-mechanical-strength nano hybrid hydrogel and preparation method thereof

Abstract

The invention discloses a sticky high-mechanical-strength nano hybrid hydrogel and a preparation method thereof. The sticky hydrogel is obtained by polymerizing an acrylamide or N-alkyl substituted acrylamide derivative in aqueous dispersion of an inorganic nano crosslinking agent namely of laponite, polyvinyl alcohol and cyclodextrin, has high mechanical strength and stickiness and can adhere to surfaces of skins, metals, glasses and ceramics. The preparation method of the sticky hydrogel comprises the following steps: dispersing the inorganic nano crosslinking agent namely laponite and a monomer into water, and stirring to obtain uniform and transparent dispersion; adding polyvinyl alcohol into a reaction mixed solution, and stirring uniformly; then adding the cyclodextrin into the reaction mixed solution, and stirring uniformly; adding an initiating agent at last; and filling a mold with the reaction solution, sealing the mold, and putting the mold into an environment of 20-25 DEG C for reaction for 12-48 hours to obtain the sticky high-mechanical-strength nano hybrid hydrogel, wherein the tensile strength of the hydrogel is more than or equal to 100kPa, and the adhesive strength is more than or equal to 10kPa.

Description

technical field

[0001] The invention relates to the polymer material field of a functional polymer-inorganic lithium algae nano-hybrid material, in particular to a viscous high-mechanical-strength nano-hybrid hydrogel and a preparation method thereof. Background technique

[0002] Hydrogel contains a large amount of water and has a perfect three-dimensional network structure endowing it with the characteristics of soft matter. This structure is similar to biological tissue, so it has important application prospects in the field of biomedical materials. Among them, viscous hydrogels have unique advantages in tissue engineering, medical dressings, and controlled release of drugs. Compared with traditional adhesives, viscous hydrogel can provide strength matching the modulus of the substrate, and has the function of transporting substances; the matching of modulus can effectively avoid cracking, and the function of adsorbing and releasing molecules makes the viscous gel Glue h...

Examples

Embodiment 1

[0031] Disperse 0.1g of LaponiteXLG gel-type product in 10mL of deoxygenated deionized water at room temperature, stir for 2 hours to obtain a uniform dispersion; then add 1g of monomer N , N - Dimethacrylamide, stirred for 2 hours to obtain a uniform and transparent mixed solution; add 0.1 g of polyvinyl alcohol with a degree of hydrolysis of 80% and a molecular weight of 10,000 to the above mixed solution and stir for 2 hours, then add 0.3 g α -Cyclodextrin was stirred for 1 hour; then argon gas was introduced for 10 minutes to remove oxygen; finally, 0.03 g of initiator potassium persulfate and 0.01 g of tetramethylethylenediamine were added to obtain a reaction solution, which was put into a mold and sealed, and placed at 20 o C environment reacted for 12h, and obtained a viscous nano-hybrid hydrogel with high mechanical strength. The tensile breaking strength of the hydrogel is 100kPa, the elongation at break is 1600%, and the bonding strength between the hydrogel and p...

Embodiment 2

[0033] Disperse 0.2g of LaponiteRD gel-type product in 10mL deoxygenated deionized water at room temperature, stir for 2 hours to obtain a uniform dispersion; then add 3g of monomeric acrylamide, and stir for 2 hours to obtain a uniform and transparent mixed solution; Add 0.5g of polyvinyl alcohol with a degree of hydrolysis of 83% and a molecular weight of 30,000 to the mixture and stir for 2 hours, then add 1g β -The cyclodextrin was stirred for 1 hour; then argon gas was introduced for 10 minutes to remove the oxygen therein; finally, 0.1 g of ammonium persulfate and 0.01 g of initiator ammonium persulfate and 0.01 g of tetramethylethylenediamine were added to obtain a reaction solution, which was put into a mold and sealed , placed at 10 oAfter reacting in C environment for 24h, a viscous nano-hybrid hydrogel with high mechanical strength was obtained. The tensile breaking strength of the hydrogel is 120kPa, the elongation at break is 2300%, and the bonding strength betwe...

Embodiment 3

[0035] Disperse 0.6g LaponiteXLS sol-type product in 10mL deoxygenated deionized water at room temperature, stir for 2h to obtain a uniform dispersion; then add 2g monomer N -Isopropylacrylamide, stirred for 2 hours to obtain a uniform and transparent mixed solution; add 0.2 g of polyvinyl alcohol with a degree of hydrolysis of 86% and a molecular weight of 100,000 to the above mixed solution and stir for 2 hours, then add 1.5 g gamma -Cyclodextrin was stirred for 1 hour; then passed through argon for 10 minutes to remove oxygen therein; finally, 0.06 g of initiator ammonium persulfate and 0.01 g of tetramethylethylenediamine were added to obtain a reaction solution, which was put into a mold and sealed , placed at 25 o After reacting for 48 hours in C environment, a viscous nano-hybrid hydrogel with high mechanical strength was obtained. The tensile breaking strength of the hydrogel is 200kPa, the elongation at break is 1800%, and the bonding strength between the hydrogel an...

technical field

[0001] The invention relates to the polymer material field of a functional polymer-inorganic lithium algae nano-hybrid material, in particular to a viscous high-mechanical-strength nano-hybrid hydrogel and a preparation method thereof. Background technique

[0002] Hydrogel contains a large amount of water and has a perfect three-dimensional network structure endowing it with the characteristics of soft matter. This structure is similar to biological tissue, so it has important application prospects in the field of biomedical materials. Among them, viscous hydrogels have unique advantages in tissue engineering, medical dressings, and controlled release of drugs. Compared with traditional adhesives, viscous hydrogel can provide strength matching the modulus of the substrate, and has the function of transporting substances; the matching of modulus can effectively avoid cracking, and the function of adsorbing and releasing molecules makes the viscous gel Glue h...

Examples

Embodiment 1

[0031] Disperse 0.1g of LaponiteXLG gel-type product in 10mL of deoxygenated deionized water at room temperature, stir for 2 hours to obtain a uniform dispersion; then add 1g of monomer N , N - Dimethacrylamide, stirred for 2 hours to obtain a uniform and transparent mixed solution; add 0.1 g of polyvinyl alcohol with a degree of hydrolysis of 80% and a molecular weight of 10,000 to the above mixed solution and stir for 2 hours, then add 0.3 g α -Cyclodextrin was stirred for 1 hour; then argon gas was introduced for 10 minutes to remove oxygen; finally, 0.03 g of initiator potassium persulfate and 0.01 g of tetramethylethylenediamine were added to obtain a reaction solution, which was put into a mold and sealed, and placed at 20 o C environment reacted for 12h, and obtained a viscous nano-hybrid hydrogel with high mechanical strength. The tensile breaking strength of the hydrogel is 100kPa, the elongation at break is 1600%, and the bonding strength between the hydrogel and p...

Embodiment 2

[0033] Disperse 0.2g of LaponiteRD gel-type product in 10mL deoxygenated deionized water at room temperature, stir for 2 hours to obtain a uniform dispersion; then add 3g of monomeric acrylamide, and stir for 2 hours to obtain a uniform and transparent mixed solution; Add 0.5g of polyvinyl alcohol with a degree of hydrolysis of 83% and a molecular weight of 30,000 to the mixture and stir for 2 hours, then add 1g β -The cyclodextrin was stirred for 1 hour; then argon gas was introduced for 10 minutes to remove the oxygen therein; finally, 0.1 g of ammonium persulfate and 0.01 g of initiator ammonium persulfate and 0.01 g of tetramethylethylenediamine were added to obtain a reaction solution, which was put into a mold and sealed , placed at 10 oAfter reacting in C environment for 24h, a viscous nano-hybrid hydrogel with high mechanical strength was obtained. The tensile breaking strength of the hydrogel is 120kPa, the elongation at break is 2300%, and the bonding strength betwe...

Embodiment 3

[0035] Disperse 0.6g LaponiteXLS sol-type product in 10mL deoxygenated deionized water at room temperature, stir for 2h to obtain a uniform dispersion; then add 2g monomer N -Isopropylacrylamide, stirred for 2 hours to obtain a uniform and transparent mixed solution; add 0.2 g of polyvinyl alcohol with a degree of hydrolysis of 86% and a molecular weight of 100,000 to the above mixed solution and stir for 2 hours, then add 1.5 g gamma -Cyclodextrin was stirred for 1 hour; then passed through argon for 10 minutes to remove oxygen therein; finally, 0.06 g of initiator ammonium persulfate and 0.01 g of tetramethylethylenediamine were added to obtain a reaction solution, which was put into a mold and sealed , placed at 25 o After reacting for 48 hours in C environment, a viscous nano-hybrid hydrogel with high mechanical strength was obtained. The tensile breaking strength of the hydrogel is 200kPa, the elongation at break is 1800%, and the bonding strength between the hydrogel an...