40results about How to "Control release speed" patented technology

The invention discloses a water-retaining controlled-release fertilizer and a preparation method thereof, and relates to the technical field of controlled-release fertilizers. According to the invention, the attapulgite is modified by a phosphoric acid solution, so that the surface of the attapulgite has acidic groups, and the groups can be adsorbed with positive ions in the fertilizer, so that nutrients are adsorbed and fixed on the surface of the attapulgite, and the speed of releasing the fertilizer nutrients into a soil solution is delayed; meanwhile, the modified attapulgite and some nutritional ingredients in the fertilizer can form indissolvable compounds, so that the nutrients are slowly released along with gradual dissolution of the compounds, and the fertilizer efficiency of the fertilizer is prolonged; when the modified attapulgite encounters water, the entering speed of water can be effectively slowed down, dissolution of nutrients in fertilizer particles is controlled, and then the slow and controlled release effect is achieved; and the modified attapulgite can regulate the pH value of the soil, so that the soil environment is more suitable for plant growth and slow release of fertilizer nutrients.

The invention discloses a dependency-free anti-aging sleep-aiding preparation and a preparation method thereof, and relates to the technical field of preparations, the anti-aging sleep-aiding preparation comprises an ellipsoidal shell and an ellipsoidal core wrapped in the ellipsoidal shell, the ellipsoidal core comprises an anti-aging agent layer, a water absorption expansion layer and a sleep-aiding agent layer which are stacked in sequence, the water absorption expansion layer protrudes at the two ends of the ellipsoidal core to form small water diversion columns; small water inlet holes are formed in the two ends of the ellipsoidal shell and are connected with small water diversion columns; a plurality of first release holes and a plurality of second release holes are formed in the circumferential surface of the ellipsoidal shell, the plurality of first release holes lead to the anti-aging agent layer, and the plurality of second release holes lead to the sleep aid layer. Through the special structural design of the ellipsoidal shell and the ellipsoidal core, isolated coexistence of anti-aging and sleep-aiding components and controllable release of the anti-aging and sleep-aiding components are achieved, so that the dual effects of anti-aging and sleep-aiding can be achieved, and it is guaranteed that the drug effect is continuously exerted.

The present invention separates and purifies chitosan in shrimp by-products, and then prepares chitosan / collagen / plant essential oil multilayer nano composite microsphere emulsion, which is applied to sunscreen skin care products. The plant essential oil has sunscreen effect, chitosan has antibacterial and anti-inflammatory properties, and collagen can repair damaged skin. By controlling the extraction and purification process of chitosan, the molecular weight of chitosan is controlled, the homogeneity of chitosan is improved, and the antibacterial property of chitosan is improved. Through the form of multilayer nano composite microsphere emulsion, the plant essential oil is protected, the volatilization of the plant essential oil is reduced; the release rate of the plant essential oil is controlled, and a slow release effect is produced; the particle size of the effective ingredient is smaller and easier to be absorbed by the skin; at the same time, a component with waterproof performance is added to the sunscreen cosmetics, so that the sunscreen skin care products of the present invention have excellent sunscreen effect and waterproof performance.

The invention relates to the field of plant growth regulators, in particular to an ultramicro-granulated energy-gathered humic acid composite preparation which is prepared from the following raw materials in parts by weight: 50-80 parts of ultramicro-granulated energy-gathered humic acid, 10-30 parts of nanoscale metal oxide, 5-20 parts of a microbial agent, 1-10 parts of a plant growth regulator and 5-15 parts of a slow release agent. According to the invention, ultrafine particle shaped humic acid, nano-scale metal oxide, a microbial agent, a plant growth regulator and a slow-release agent are organically combined. The effect of the soil conditioner is far better than that of a single component or a traditional soil conditioner.

The invention relates to a preparation method of a sodium alginate composite hydrogel microneedle for treating pathological scars, and belongs to the technical field of hydrogel microneedles, the microneedle takes sodium alginate as a main material, the sodium alginate is methylated to obtain methylacryloylated sodium alginate AlgMA, hollow manganese dioxide nanoparticles loaded with matrix metalloproteinase are added, and the microneedle is prepared by a hydrothermal method. A hydrogel microneedle filling solution is obtained; the preparation method comprises the following steps: transferring the hydrogel microneedle into a PDMS microneedle mold, carrying out negative pressure vacuum bubble removal, drying and concentrating twice in a drying oven, carrying out photopolymerization crosslinking, forming a solid hydrogel microneedle tip, adding a 20% PVA solution, and drying in the drying oven to form the microneedle substrate, and the preparation method is simple, convenient and efficient, has industrial application potential, and is suitable for the scenes of drug delivery, skin care and the like; according to the application of the sodium alginate composite hydrogel microneedle in pathological scar drug delivery, the sodium alginate composite hydrogel microneedle has excellent mechanical strength and biocompatibility, and painless and noninvasive drug delivery can be carried out on the surface of scar skin.

The invention relates to the technical field of flocculating agents, and discloses a flocculating agent for high-concentration azo printing and dyeing wastewater, which is prepared from the following components in parts by weight: 4 to 5 parts of hydroxypropyl chitosan derivative, 2 to 3 parts of sodium silicate solution, 0.5 to 1 part of sulfuric acid, 2 to 3 parts of ferric sulfate solution, 1 to 3 parts of zinc sulfate solution, and 4 to 5 parts of polyaluminum chloride solution and composite antibacterial agent. The preparation method comprises the following steps: preparing a sodium silicate solution, slowly dropwise adding the sodium silicate solution into sulfuric acid, and activating to obtain a polysilicic acid solution; sequentially adding a ferric sulfate solution, a zinc sulfate solution and a 50-500mg / L polyaluminum chloride solution, and standing and curing to obtain the polysilicate ferric zinc aluminum flocculant. The preparation method comprises the following steps: firstly, preparing a polysilicate ferric zinc aluminum flocculant, then slowly adding a melamine solution, carrying out ultrasonic action to obtain a carbonitrided polysilicate ferric zinc aluminum flocculant, and carrying out carbonitriding treatment on the polysilicate ferric zinc aluminum flocculant combined with metal ions to delay gelation of the polysilicate flocculant, so that the polysilicate flocculant can be stored for a longer time.

The invention discloses a pesticide microcapsule and its application, belonging to the technical field of pesticides. The pesticide microcapsule is prepared by the following method: adding the pesticide active ingredient to ethyl acetate, and then adding polylactic acid, stirring evenly, and obtaining an organic phase; the pesticide active ingredient is composed of a bifenthrin-thiamethoxam complex and piperine in a mass ratio of 1: (1-3); polyvinyl alcohol is dissolved in water to obtain an aqueous phase; under ice-water bath conditions, the organic phase is added dropwise to the aqueous phase, and stirred at the same time to form an emulsion; the emulsion is stirred and evaporated, centrifuged, washed, and dried to obtain a pesticide microcapsule. The present invention prepares pesticide microcapsules by compounding bifenthrin, clothianidin and piperine, effectively avoiding the drug resistance of pests caused by the action of a single agent, and piperine not only directly produces a toxic effect on pests, but also can enhance the insecticidal effect of bifenthrin and clothianidin, and achieves a synergistic effect of 1+1>2.

According to the oral care solution composition disclosed by the invention, glucanase is encapsulated by using a pH sensitive microcapsule, so that the stability and activity of enzyme in a complex oral environment are maintained. The pH-sensitive microcapsule is prepared from boric acid modified poly (2-hydroxyethyl methacrylate) (PHEMA), a boric acid group serves as a lactic acid specific ligand and is covalently bound and polymerized with a monomer of HEMA to form a pH-sensitive polymer, and in an oral acidic environment, disintegration of the polymer promotes release of glucanase, it is ensured that enzyme is released at a needed place and time, and the pH-sensitive microcapsule has the advantages that the pH-sensitive microcapsule can be used for preparing the oral cavity. Therefore, glucan in the oral cavity is accurately decomposed, bacterial adhesion and biofilm formation are reduced, and improvement of oral cavity microorganism balance and improvement of user experience are facilitated.

The invention discloses a nicotine hard candy and a manufacturing method thereof. The nicotine hard candy comprises the following raw materials in parts by mass: 1-9 parts of a nicotine active material; 1-2 parts of a green tea extract; 1 to 2 parts of microencapsulated capsaicin; 5-15 parts of a first sweetening agent; and 60-80 parts of a carrier material. The nicotine hard candy can effectively inhibit appetite and control body weight.

The invention provides a method for preparing a composite solid electrolyte based on a nano-structure initiator adsorption carrier, and the composite solid electrolyte is prepared from the following raw material components in parts by weight: 20-40 parts of a micromolecule polymeric monomer, 1-4 parts of an initiator, 2-6 parts of a lithium salt, 3-9 parts of an inorganic nano-structure lithium ion conductor and 10-20 parts of an organic solvent, the preparation method is simple, the electrochemical performance and the cycle performance of the composite electrolyte are improved by forming a PLiMA coating layer on the surface of an inorganic nano lithium ion conductor and controlling the release speed of an initiator, meanwhile, PLiMA is a lithium salinized acrylic polymer, contains lithium ions, can directly provide a lithium ion source, and can be used for preparing a lithium ion battery as the PLiMA carries the lithium ions, so that the service life of the lithium ion battery is prolonged. The PLiMA can increase the overall lithium ion concentration and conductivity.

The present invention discloses a skin whitening and repairing composition, a preparation method and an application thereof, wherein the composition is composed of the following substances by mass: 2 to 5 parts of active extract component A, 1 to 3 parts of active extract component B, 10 to 48 parts of cyclodextrin, and 2 to 3 parts of hyaluronic acid. The active ingredients are included in cyclodextrin to improve the stability of the active ingredients and reduce the influence of environmental factors on the active ingredients. In addition, cyclodextrin can control the release rate of the active ingredients, so that the skin care products can achieve a longer-lasting effect.

The invention provides an application of a sustained-release film coating premix in preparation of methylphenidate hydrochloride tablets. The provided slow-release film coating premix is prepared from the following components in parts by weight: 35-55 parts of a film forming material, 18-32 parts of a plasticizer, 14-22 parts of a coloring agent, 1-4 parts of a dispersing agent, 5-15 parts of an anti-sticking agent and 40-60 parts of a solvent, and the film forming material is prepared from hydroxypropyl methylcellulose, polyvinyl alcohol and povidone K30; the plasticizer comprises polyethylene glycol 6000 and propylene glycol; the solvent is water. The sustained-release film-coated premix is used for preparing the methylphenidate hydrochloride sustained-release tablet, the release speed of the medicine can be controlled, and the stability, safety and effectiveness of the medicine are improved.

This invention discloses a negative electrode current collector, comprising a basic foil material; multiple vertically penetrating through-holes are uniformly distributed at equal intervals on the basic foil material; each through-hole contains a lithium replenishment filler; the lithium replenishment filler includes lithium metal powder; the lithium replenishment filler is a multi-layered lithium replenishment filler; the multi-layered lithium replenishment filler includes at least one layer of lithium metal powder. This invention also discloses a negative electrode sheet and a lithium replenishment-type battery. This invention is scientifically designed, effectively improving the energy density of the battery cell, ensuring the safety of the lithium replenishment process, and allowing for controlled and gradual lithium replenishment, thus possessing significant practical value.

The invention relates to the technical field of chemical copper deposition, in particular to chemical copper deposition complex liquid and a preparation method thereof.The chemical copper deposition complex liquid is prepared from, by weight, 1.0%-1.4% of copper sulfate, 3%-6% of a reducing agent, 8%-12% of sodium hydroxide, 5%-15% of a complexing agent, 0.1%-0.5% of a stabilizer, 0.3%-0.8% of an accelerator, 1%-3% of a buffering agent, 1%-2% of a surfactant and the balance water; the accelerator is obtained by mixing sodium thiosulfate, nickel sulfate and tungstate according to the weight part ratio of (3-5): (1-3): 2, and by adopting the formula, the copper deposition speed can be increased, and the copper deposition efficiency can be improved. The chemical thick copper deposition complex liquid can form a uniform and compact copper layer. The copper layer has good conductivity, adhesive force and corrosion resistance, and can meet the requirements for the quality of the copper layer in the fields of electronics, PCB manufacturing and the like.

The present invention relates to the technical field of calcium fertilizer, and in particular to a slow-release nano calcium fertilizer and a preparation method and application thereof, wherein the slow-release nano calcium fertilizer comprises a core and a slow-release layer coated on the outer surface of the core, wherein the core comprises the following raw materials by mass: 35-40 parts of nano suspended calcium, 10-15 parts of superphosphate, 15-20 parts of urea, 2-5 parts of slow-release agent, and 5-10 parts of sugar alcohol, and the slow-release layer comprises the following raw materials by mass: 20-25 parts of chitosan, 25-35 parts of sodium alginate, 15-20 parts of starch, 5-10 parts of lignin, and 30-35 parts of mineral potassium humate. The core in the fertilizer contains nano-sized calcium, which is more easily adsorbed by the root hairs or root tips of plants, and the slow-release layer can control the release rate of the calcium fertilizer, so that it can reduce the loss and waste of nutrients while meeting the needs of crops.

The invention discloses a betaine composition with an antihypertensive effect and a preparation method thereof, and belongs to the technical field of pharmaceutical compositions.The preparation method comprises the steps of tablet core preparation, primary coating liquid preparation, secondary coating liquid preparation, primary coating and secondary coating; the step of preparing the primary coating liquid comprises the steps of preparing a filling agent and performing primary mixing; the step of preparing the secondary coating solution comprises the steps of preparing a supramolecular composition and performing secondary mixing; according to the prepared betaine composition, the problem that the blood pressure is too low after the prepared betaine composition is used can be avoided by controlling the release speed of the angiotensin converting enzyme inhibitor, and the prepared betaine composition is good in storage resistance, high in percent of pass and suitable for industrial production. And the content difference of the angiotensin converting enzyme inhibitor in the prepared betaine mixture is small.

This invention relates to the agricultural field, specifically to a method for preparing and applying a carbon dioxide fusion element trap. It addresses the problem that polymeric film-forming agents added to foliar fertilizers easily form a continuous, dense, and impermeable physical film on the leaf surface, making it difficult for carbon dioxide to enter, interfering with normal photosynthesis and transpiration, and thus causing abnormal leaf metabolism. The method involves immersing mesoporous silica microspheres in a PEI solution to obtain PEI-loaded microspheres, then adding a solution of gelatin, chitosan, glycerol, and glutaraldehyde to deionized water to form a composite gel base solution. Finally, selenomethionine, seaweed oligopeptides, and yeast extract are mixed with the composite gel base solution in warm water to obtain the carbon dioxide fusion element trap. This invention, through careful material selection and structural design, cleverly achieves a balance between strong adhesion and high permeability, allowing it to firmly adhere to the leaf surface and eliminating the defect of clogging leaf stomata.

The utility model discloses an intelligent sachet temperature control releasing device, and belongs to the technical field of sachet releasing devices. Comprising an air supply module, a supporting module and an adjusting module, the air supply module comprises a base, an air supply part is embedded in the base, the supporting module comprises a connecting frame installed on the top face of the base, a grating is installed in the connecting frame and used for supporting a sachet, the air supply part conveys air into the connecting frame, and a temperature sensor is installed on the outer side of the connecting frame; an analog-to-digital converter is installed in the connecting frame, the adjusting module comprises a box cover clamped to the top face of the connecting frame, a microcontroller is installed in the box cover, a plurality of air outlet grooves are formed in the top face of the box cover, rotating shafts are rotationally connected into the air outlet grooves, and wind blocking strips are installed on the outer sides of the rotating shafts. The driving piece adjusts the opening and closing angle of the wind blocking strip.

The invention relates to a controlled-release linalool emulsion based on a ternary system as well as a preparation method and application of the controlled-release linalool emulsion. The linalool emulsion is an oil-in-water Pickering emulsion composed of a water phase and an oil phase, the water phase comprises a ternary system composed of soybean protein isolate, pectin and hydroxypropyl methyl cellulose, and the oil phase is linalool essential oil. The preparation method comprises the following steps: respectively preparing soybean protein isolate, pectin and hydroxypropyl methyl cellulose solutions, and mixing to obtain a ternary composite water phase; and mixing the ternary composite water phase with the oil phase, and carrying out high-pressure homogenization treatment and ultrasonic treatment under a low-temperature condition to obtain the controlled-release linalool emulsion based on the ternary system. Compared with the prior art, the linalool essential oil emulsion embedding method solves the problem that linalool is easy to volatilize, and can be used in the fields of fruit and vegetable fresh keeping, tea fragrance maintaining and the like.

The utility model belongs to the technical field of reinforcing steel bar production and processing, disclose a reinforcing steel bar brake pay -off device, including frame and the multiple pay -off rack and multiple first wire guide mechanism of setting up in pairs on frame, pay -off rack includes pay -off base, drive assembly, main shaft, carousel, pay -off stand and connecting plate, the output of drive assembly connects main shaft to drive main shaft rotation, the bottom end of multiple pay -off stand is fixedly arranged in carousel, multiple pay -off stand is fixedly connected with main shaft through connecting plate, reinforcing steel bar can be wound in multiple pay -off stand, and one end of reinforcing steel bar is inserted in first wire guide mechanism and is led out. The utility model can control the release speed of reinforcing steel bar, stabilizes reinforcing steel bar pay -off process, can reduce the length deviation or displacement deviation caused by the uneven pay -off speed, ensures that reinforcing steel bar arrangement meets the design requirement, and reinforcing steel bars of different diameters and strengths can be fed synchronously, improving feeding efficiency.

The invention belongs to the technical field of biological materials, and particularly relates to a drug carrier for treating rheumatism as well as a preparation method and application thereof. The traditional Chinese medicine carrier is composed of a SiO2 material and a Fe3O4 material, the SiO2 material is of a spherical hollow structure, the Fe3O4 material is of a solid sphere shape, the Fe3O4 material is arranged in the SiO2 material, and a cavity structure is formed between the Fe3O4 material and the inner wall of the SiO2 material. The drug carrier has the advantages of large drug loading capacity and magnetic guidance. The composition is combined with medicines for treating rheumatism and can be applied to the field of rheumatism.

The invention belongs to the technical field of heavy oil ultra-low pressure, and particularly relates to a reaction-stable heavy oil ultra-low pressure mesoscopic hydrogenation reaction kettle which comprises a reaction kettle body and a carbon-based microsphere moving part arranged in the reaction kettle body, a turnover feeding device is arranged in the reaction kettle body; a stirring mechanism is arranged in the reaction kettle body and is used for stirring a reaction material in the reaction kettle body; a suspension liquid collecting device is arranged on the upper layer in the reaction kettle body; a transverse circumferential protruding part is arranged in the circumferential direction of the interior of the reaction kettle body, a circumferential flow direction groove is formed in the circumferential protruding part, a rolling shaft is arranged in the circumferential flow direction groove, and the rolling shaft slides in the circumferential flow direction groove in the circumferential direction; the heavy oil ultra-low pressure mesoscopic hydrogenation reaction kettle for stable reaction has the effects of improving the mass transfer efficiency, improving the conversion per pass, improving the reaction rate, improving the overall dispersity and improving the coke bearing property.

The invention discloses a granular ball, a preparation method thereof and a product containing the granular ball, and belongs to the technical field of health care. The granules are prepared from the following raw materials in parts by weight: 500-650 parts of vegetation matrix material powder, 80-140 parts of an excipient and 250-350 parts of a traditional Chinese medicine concentrated solution, the grass and tree matrix material powder is selected from bamboo, wood, straw or grass powder, and the excipient is selected from clayey soil, loam, sandy soil, red loam, yellow loam, black soil, desert soil, wet soil, lithologic soil or high mountain soil; the particle size of the grass and tree matrix material powder is 80-200 meshes; the traditional Chinese medicine concentrated solution is a concentrated solution containing traditional Chinese medicine components; the granular ball is obtained by mixing, granulating and polishing raw materials, and the size of the granular ball is 5-8mm. The pillow containing the particles is good in overall performance, so that the pillow has good use experience. The particles have high hardness and fluidity and low hygroscopicity and powder falling rate, and volatile components can be released for a long time.

The invention discloses a technology for preparing a fertilizer from leucine fermentation liquor and nitrogen-fixing microorganisms, and relates to the technical field of fertilizer preparation, and the technology comprises the steps of leucine fermentation liquor preparation, nitrogen-fixing microorganism culture and leucine fermentation liquor and nitrogen-fixing microorganism mixing. The problem that the nutritional ingredients are single and insufficient when leucine fermentation liquor is independently used can be solved, leucine can participate in plant protein synthesis, regulate the metabolic pathway and enhance the immunity and stress resistance of plants, nitrogen-fixing microorganisms can convert nitrogen in air into a nitrogen source capable of being utilized by the plants, and the nitrogen-fixing microorganisms and the nitrogen-fixing microorganisms are mixed to prepare the fertilizer. According to the present invention, with the application of the leucine fermentation broth, the more comprehensive nutrition can be provided for the plant, the synthesis of the leucine and the growth stability of the strain are further promoted by adding the novel bioactive factor, the quality and the nutritional value of the leucine fermentation broth are improved, and the activity and the breeding speed of the nitrogen-fixing microorganism are substantially improved by adding the growth promoter.

The present invention belongs to the field of biomedicine, and specifically relates to a sodium pyruvate sustained-release nanosystem based on targeted modification, and a preparation method and application thereof. The preparation method of the sustained-release nanosystem comprises the following steps: a. preparing modified silk fibroin; b. under homogenization conditions, adding a mixed aqueous solution of sodium phytate and sodium pyruvate to a modified silk fibroin aqueous solution, obtaining a mixed solution after homogenization, stirring the mixed solution for reaction, centrifuging the reaction solution after the reaction is completed, collecting the precipitate, washing, and dialyzing to obtain the sodium pyruvate sustained-release nanosystem based on targeted modification. The sustained-release nanosystem has good biocompatibility, can be specifically enriched in lung lesions and realize the sustained release of sodium pyruvate, has significant targeting and sustained-release effects, and is suitable for preparing drugs for treating lung diseases.

This invention discloses a method for formulating and producing high-purity emulsion-type cosmetics, aiming to solve the problem that increasing the amount of emulsifier to ensure sufficient stability of the emulsion often leads to skin irritation. Furthermore, conventional processes result in emulsions with a wide and uneven particle size distribution, which negatively impacts the product's feel on the skin. The key technical points are: a method for formulating and producing high-purity emulsion-type cosmetics, comprising the following steps: emulsion oil phase preparation, emulsion aqueous phase preparation, nanocrystal seed preparation, emulsion preparation, dynamic pressure stirring, active microcapsule preparation, mixing and blending, and cooling and filling. This invention's method for formulating and producing high-purity emulsion-type cosmetics, through purification of oil and aqueous phase raw materials, addition of nano-silica with good compatibility with both oil and aqueous phases, dynamic stirring, and microcapsule technology, reduces the amount of emulsifier used while ensuring stability, and promotes the release and utilization rate of active ingredients.

The invention belongs to the technical field of personal care products, and particularly relates to a China-hemp antibacterial cotton sliver and a preparation method thereof. The hemp fibers and the bamboo fibers are mixed, the combination of the hemp fibers and the bamboo fibers can enhance the overall antibacterial property and hygroscopicity of the cotton sliver, the softness and comfort of the hemp fibers and the bamboo fibers are improved after biological enzyme treatment, the hemp fibers and the bamboo fibers have good compatibility with the plant extract, the activity of the plant extract is kept, and the cotton sliver is good in antibacterial property and antibacterial property. The prepared plant composite essence enables the plant essence to be slowly released, and it is ensured that the cotton sliver continuously plays a role in inhibiting bacteria and relieving in the using process. The prepared China-hemp antibacterial cotton sliver has the effects of long-acting bacteriostasis, anti-inflammation, analgesia and long-acting relieving, the risk of inflammation infection can be effectively reduced, and a durable and comfortable safety guard is brought.

The invention relates to the field of seed treatment, and provides a seed coating agent and a preparation technology thereof.The seed coating agent is prepared from, by weight, 14-16 parts of chitosan modified carbomer hydrogel, 10-14 parts of polyvinyl alcohol, 2-6 parts of sodium carboxymethyl cellulose, 6-8 parts of calcium peroxide, 5-10 parts of seaweed extract, 30-40 parts of filler and 0.4-0.6 part of antibacterial agent; the preparation method comprises the following steps: preparing the chitosan modified carbomer hydrogel, adding the polyvinyl alcohol, the sodium carboxymethyl cellulose and the calcium peroxide into the chitosan modified carbomer hydrogel, mixing for the first time, adding the seaweed extract, the filler and the antibacterial agent, and mixing for the second time. The seed coating agent is prepared through specific component selection, the adhesive force and uniformity of the seed coating agent on the surfaces of seeds are improved, and the adhesive force and durability of the seed coating agent are also improved, so that better seed germination and crop protection effects are ensured.

The invention discloses a multilayer apocarya seedling cultivating and growing device which comprises a concentric-square-shaped vertical support A and a concentric-square-shaped vertical support B arranged on the left side of the concentric-square-shaped vertical support A. A cultivating and growing placing frame A, a cultivating and growing placing frame B and a cultivating and growing placing frame C are connected between the concentric-square-shaped vertical support A and the concentric-square-shaped vertical support B respectively. A novel protection type fertilization device is additionally arranged in each cultivation and growth pot on the multilayer type apocarya seedling cultivation and growth device, the protection type fertilization device is mainly characterized in that a proper amount of fertilizer is stored in a metal fertilization barrel, and then the metal fertilization barrel is inserted into soil in the cultivation and growth pots through an insertion conical tip; the small release holes in the metal fertilization cylinder can make the fertilizer slowly permeate into soil, compared with direct fertilizer spreading, the release speed of the fertilizer can be controlled more accurately, fertilizer damage caused by rapid dissolution of the quick-acting fertilizer due to watering and other factors is avoided, and plants can continuously absorb nutrients.

This application belongs to the field of food or pharmaceutical technology, specifically relating to a lozenge and its preparation method. The lozenge includes a granular composition comprising the following components: an active substance, a cationic resin, cationic salt sustained-release granules, and a filler; wherein the active substance includes at least one of the following: nicotine or a nicotine derivative. This solution incorporates cationic salt sustained-release granules into the lozenge, which not only effectively prevents the rapid dissolution of the cationic salt, allowing it to maintain an effective concentration in the oral cavity for a prolonged period, thus facilitating sufficient contact with the cationic resin to ensure nicotine replacement, but also regulates the release rate of the cationic salt, thereby regulating the nicotine replacement rate.