6 results about "Punctal plug" patented technology

Embodiments of the disclosure provide ophthalmic compositions and methods of use thereof. The embodiments disclose ophthalmic compositions including devices such as a punctal plug. Some embodiments are directed to a method of preparing and using such devices. One embodiment provides a method of dissolving a hydrophilic polymer and an active pharmaceutical ingredient (API) in alcohol to form a hydrophilic polymer / API solution, where the API includes tacrolimus, spray drying the hydrophilic polymer / API solution to form a hydrophilic polymer / API mixture, mixing the hydrophilic polymer / API mixture with a binder to form an API paste, and curing the API paste to form a punctal plug, where the punctal plug is configured to release an effective amount of the API for a treatment period of 30 days to one year.

The punctal plug insertion device of the present invention comprises: a catheter hub having a channel formed to contain a punctal plug; and a main body coupled to the catheter hub and including an external force application unit for applying an external force to the punctal plug contained in the catheter hub.

A punctum plug or lacrimal insert is constructed of a monolithic material, such that the punctum plug is configured to turn approximately 90 degrees upon insertion into a canaliculus of an eye. The punctum plug or lacrimal insert may include high-molecular-weight polysaccharide and added plasticizers.

The invention belongs to the field of medical instruments, and particularly relates to a degradable tracing punctum plug and a preparation method and application thereof. The preparation method comprises the steps that polylactic acid and a coloring agent are mixed to obtain colored polylactic acid; mixing the colored polylactic acid with an alkaline inorganic filler to obtain a mixture; carrying out segmented temperature control injection molding treatment on the mixture to obtain an injection molding product; the injection molding product is treated for 5-120 s under the conditions of 25-40 DEG C and 20-50 Mpa, and a punctal plug precursor is obtained; and carrying out heat preservation treatment on the punctum plug precursor to obtain the degradable tracing punctum plug. According to the preparation method, raw materials are easy to obtain, the process is simple, the alkaline inorganic filler regulates and controls the degradation rate and inhibits inflammation caused by an acidic product generated by degradation of polylactic acid in the use process of the punctal plug, intraoperative visual tracing and positioning are achieved through the coloring agent, and the crystallinity of the material is improved through the low-temperature pressure maintaining process; the problems of brittle fracture and uncontrollable degradation rate of the degradable punctum plug are solved, and the degradable punctum plug has a wide prospect in minimally invasive treatment of xerophthalmia.

The utility model provides a lacrimal point plug implanter without expanding a lacrimal point, which belongs to the technical field of ophthalmology treatment and comprises a lacrimal point plug, a release component is arranged at the tail of the lacrimal point plug, and an implanter main body component is slidably connected into the release component. The problems that an existing lacrimal point plug implanting device is relatively large in clinical operation difficulty, lacrimal point expansion is not in place, a lacrimal point plug is difficult to implant, the operation time is prolonged, the pain of a patient is increased, the lacrimal point plug can fall off in the expansion process, the size of the lacrimal point plug is extremely small, the lacrimal point plug cannot be found after falling off, and the practicability of the device is reduced are solved.