The present invention is directed to an infusion clamp including a first clamping member having a first side surface, a second side surface, a first mating surface, and an aperture disposed between the first side surface and the second side surface thereby forming a passageway there between; a second clamping member having a third side surface, a fourth side surface, and a second mating surface; a hinge member disposed along and in communication with first clamping member and second clamping member, thereby facilitating the movement of the infusion device from the closed position of the infusion clamp to the plurality of opened positions of the infusion clamp, and from the plurality of opened positions to the closed position; and an infusion device support member disposed above the passageway thereby permitting an infusion device to be disposed within the infusion device support member and through the passageway. The infusion clamp permits quick and easy attachment of an infusion device, e.g., a catheter, to a chambered body, e.g., the right atrium of the heart, for infusion of fluid into the chambered body such as during emergency surgery or triage on a patient. Methods of infusing chambered bodies are also disclosed.