11 results about "Collagen Punctal Plugs" patented technology

The present disclosure provides devices and methods for the treatment of ophthalmological conditions such as dry eye. Among the devices provided are punctal plugs and devices for inserting punctal plugs. The punctal plugs may be shaped for insertion in the punctum and / or the canaliculus. They may also be coated with a bioadhesive. Methods for inserting the punctal plugs are provided, as well as methods for preparing bioadhesive-coated punctal plugs. A method is also provided to treat dry-eye using a bioadhesive without use of a punctal plug.

Embodiments of the disclosure provide ophthalmic compositions and methods of use thereof. The embodiments disclose ophthalmic compositions including devices such as a punctal plug. Some embodiments are directed to a method of preparing and using such devices. One embodiment provides a method of dissolving a hydrophilic polymer and an active pharmaceutical ingredient (API) in alcohol to form a hydrophilic polymer / API solution, where the API includes tacrolimus, spray drying the hydrophilic polymer / API solution to form a hydrophilic polymer / API mixture, mixing the hydrophilic polymer / API mixture with a binder to form an API paste, and curing the API paste to form a punctal plug, where the punctal plug is configured to release an effective amount of the API for a treatment period of 30 days to one year.

The punctal plug insertion device of the present invention comprises: a catheter hub having a channel formed to contain a punctal plug; and a main body coupled to the catheter hub and including an external force application unit for applying an external force to the punctal plug contained in the catheter hub.

A punctum plug or lacrimal insert is constructed of a monolithic material, such that the punctum plug is configured to turn approximately 90 degrees upon insertion into a canaliculus of an eye. The punctum plug or lacrimal insert may include high-molecular-weight polysaccharide and added plasticizers.

The present disclosure provides devices and methods for the treatment of ophthalmological conditions such as dry eye. Among the devices provided are punctal plugs and devices for inserting punctal plugs. The punctal plugs may be shaped for insertion in the punctum and / or the canaliculus. They may also be coated with a bioadhesive. Methods for inserting the punctal plugs are provided, as well as methods for preparing bioadhesive-coated punctal plugs. A method is also provided to treat dry-eye using a bioadhesive without use of a punctal plug.

The invention discloses a polyvinyl alcohol hydrogel punctal plug and a preparation method thereof. The two ends of the punctum plug are provided with a cap structure and an anchor structure respectively, the middle of the punctum plug is provided with a conical shaft structure with round ribs, and no central blind hole is formed. As the punctal plug is small in volume, the punctal plug is prepared by a method of combining injection molding, double crosslinking of physical crosslinking and chemical crosslinking, an excipient gradient soaking and shaping process and the like, the obtained punctal plug is uniform in crosslinking and stable in form, and can be quickly expanded after being implanted, and the risks of separation and bacterial infection are reduced.

The present invention relates to: a punctal plug comprising a shape memory polymer; and a manufacturing method thereof. More specifically, the present invention relates to: a punctal plug made of a shape memory polymer, which includes a copolymer of lactone and glycidyl methacrylate, and located in a punctal opening of a lacrimal duct to prevent lacrimal fluid from flowing in the lacrimal duct; and a manufacturing method thereof. The punctal plug according to the present invention is made of a material having biocompatibility and shape memory properties, and thus has the advantages of being easy to insert and simple to fix, and being easy to remove by a head formed at the top of an insert. In addition, the copolymer of lactone and glycidyl methacrylate is appropriately blended, and thus the punctal plug can be applied to the lacrimal duct without causing a foreign body sensation. Moreover, the punctal plug can block the punctum without becoming dislodged even under everyday pressure generated by sneezing and the like, and thus can be effectively used in punctal occlusion procedures.

A punctum plug or lacrimal insert is constructed of a monolithic material, such that the punctum plug is configured to turn approximately 90 degrees upon insertion into a canaliculus of an eye. The punctum plug or lacrimal insert may include high-molecular-weight polysaccharide and added plasticizers.

A medical device may comprise a body including a mixture of polyvinylpyrrolidone (“PVP”) and mitomycin. The medical device may be in any size or shape such that the medical device may be inserted into living tissue, including, but not limited to, a lacrimal punctal plug and a stent. The mixture of PVP and mitomycin may be coated on a portion of the medical device, contained within a cavity on the medical device, disposed on the surface of the medical device or configured as part of the medical device such that the mixture of PVP and mitomycin can be delivered to tissue.

The utility model discloses a punctum plug extractor, which relates to the technical field of medical instruments and comprises an expander and an implanter, the implanter and the expander are detachably connected into an integral structure, an expansion tip and an implantation column are respectively arranged at the ends of the expander and the implanter far away from the butt joint, a through air passage is arranged in the middle of the expander, and a through hole is formed in the middle of the implanter. The air channel is provided with an air inlet at the dilation tip, and the other end is provided with a negative pressure connecting end. The device further comprises a negative pressure generator, and after the dilator and the implanter are separated, the negative pressure generator can be connected to the negative pressure connecting end, negative pressure is formed in the airway, and the negative pressure is used for adsorbing a punctum plug in punctum tissue. The negative pressure is formed in the lacrimal plug, the lacrimal plug is adsorbed and taken out from the lacrimal tissue, the lacrimal plug does not need to be taken out in a saline water washing mode, discomfort when the lacrimal plug is taken out can be relieved, and meanwhile the taking-out efficiency of the lacrimal plug can be improved.