87results about "Preparation by halogen replacement" patented technology

Systems and methods for the preparation of (Z)-1, 1, 1, 4, 4, 4-hexafluoro-2-butene are provided. Compositions prepared according to one or more of the systems and methods described herein and methods of using these compositions are also provided.

The invention relates to an improved process for the manufacture of a fluorinated organic compound, wherein the process comprises a fluorination reaction of an organic precursor compound having at least one chlorine substituent and / or at least one double bond, and said organic precursor compound is reacted in liquid phase in HF (hydrogen fluoride) serving as solvent and fluorinating agent in the presence of a fluorinating catalyst, and wherein the fluorination reaction is performed in liquid phase in a SiC block chemical reactor, and wherein the reaction mixture is withdrawn from SiC block chemical reactor, and wherein the process comprises optionally isolating and / or purifying the targeted fluorinated organic compound.

The application discloses a continuous production process and equipment for a trifluoromethylbenzene tower, and belongs to the field of organic fluorine chemistry. The production process comprises the following steps: S1: continuously feeding trichloromethylbenzene and hydrogen fluoride into a tower reactor connected with a heat exchanger circulating cooling system in a reverse direction, so that a three-stage continuous fluorination reaction occurs in the tower reactor to obtain crude trifluoromethylbenzene, and unreacted hydrogen fluoride is separated into liquid at the top of the tower and then flows back into the tower reactor; S2: the crude trifluoromethylbenzene obtained in the reaction is subjected to nitrogen bubbling in a bubble tower, and then is continuously distilled in a rectifying tower to obtain finished trifluoromethylbenzene; and S3: byproduct hydrogen chloride generated in the fluorination reaction is introduced into a hydrochloric acid tank to obtain hydrochloric acid, and the content of hydrofluoric acid in the hydrochloric acid is less than 1000 ppm. The method can greatly improve the utilization rate of raw material hydrogen fluoride, improve the purity of byproduct hydrochloric acid, reduce the generation amount of waste acid, avoid the sharp change of pressure in the reaction process, and realize large-scale, continuous, stable and safe production of trifluoromethylbenzene.

The present invention provides a method for the co-production of 1,1-difluoroethane and vinyl chloride, including: (a) vaporizing dichloroethane and hydrogen fluoride, and delivering the vaporized dichloroethane and hydrogen fluoride into a reactor for a catalytic reaction under the action of a catalyst to obtain a reaction product; (b) delivering the reaction product into a first rectifying tower for separation to obtain an overhead product from the first rectifying tower and a bottom product from the first rectifying tower; (c) delivering the overhead product from the first rectifying tower into a second rectifying tower for separation to obtain hydrogen chloride and a bottom product from the second rectifying tower; (d) delivering the bottom product from the second rectifying tower into a purifying tower for purification to obtain an overhead product from the purifying tower; (e) simultaneously delivering the overhead product from the purifying tower and a saturated organic solvent into a third rectifying tower for separation to obtain a 1,1-difluoroethane product and a bottom product from the third rectifying tower; and (f) delivering the bottom product from the third rectifying tower into a fourth rectifying tower for separation to obtain a vinyl chloride product and a bottom stream from the fourth rectifying tower. The present invention has the advantages of simple process, high conversion rate, and good product quality.

The invention relates to bio-based vinylidene difluoride. The invention also relates to processes for preparing bio-based vinylidene difluoride from various renewable raw materials. The invention further relates to vinylidene difluoride homopolymers obtained by polymerization of said monomer, as well as copolymers obtained by copolymerization of said monomer with one or more compatible co-monomers. Finally, the invention relates to the use of said homopolymers or copolymers in applications such as chemical engineering or electronics, particularly consumer electronic devices.

The invention provides a fluorination catalyst composition, a preparation method and application thereof, and a method for catalyzing 1, 1, 1, 3, 3-pentachloropropane to generate E-1-chloro-3, 3, 3-trifluoropropene, and belongs to the field of materials. The fluorination catalyst composition comprises a main catalyst and a third metal element loaded on the main catalyst, wherein the main catalyst is biomass charcoal simultaneously modified by a first metal element and a second metal element; wherein the first metal element comprises at least one of rare earth metal elements; the second metal element comprises at least one of Zr, Nb, Mo, V, Fe, Mn, Ti, Hf, Ga, In and Sn; the third metal element comprises at least one of Mg, Ca, Ba and Sr. The fluorination catalyst composition provided by the invention can efficiently catalyze 1, 1, 1, 3, 3-pentachloropropane to generate a gas phase fluorination reaction to generate E-1-chloro-3, 3, 3-trifluoropropene, has the advantages of high conversion rate, strong selectivity, long service life and the like, and is suitable for wide application.

Minimum-boiling, heterogeneous azeotropic and azeotrope-like compositions including 1,1,2,2,3-pentachloropropane (HCC-240aa) and hydrogen fluoride (HF), as well as methods for using these azeotropic or azeotrope-like compositions in the production of trifluorochloropropenes.

There is provided a method for producing chlorofluorobutane (CFB) by forming chlorinated butadiene by dimerizing trichloroethylene (TCE) and fluorinating hydrogen atoms of the chlorinated butadiene. Trichloroethylene (TCE) is dimerized by using a dimer represented by the following formula (1) as a solvent and in the presence of a free radical generating agent at a temperature of 100° C. or higher. Hexachlorobutadiene (C4Cl6) is produced from the above dimer by chlorination and dehydrochlorination reaction, and further, the chlorofluorobutane (CFB) is produced by fluorinating the hexachlorobutadiene.

Processes for producing at least one of 2-chloro-3,3,3-trifluoropropene (HCFO-1233xf) or 2,3-dichloro-3,3-difluoropropene (HCFO-1232xf) from 1,1,2,3-tetrachloro-1-propene (HCO-1230xa), in the absence of a catalyst, are provided.

A system may include a pre-pressurized canister filled with one or more polymeric materials and one or more low global warming potential (GWP) propellants. The one or more low GWP propellants may include at least one of carbon dioxide, nitrogen, or trans-1-Chloro-3,3,3-trifluoropropene. The system may include a valve sub-system including a dispensing valve configured to couple to the pre-pressurized canister and a valve control mechanism configured to regulate a pressure of the pre-pressurized canister to cause the pre-pressurized canister to release the one or more polymeric materials. The system may include a dispensing sub-system configured to fluidically couple the pre-pressurized canister to the valve sub-system. The dispensing sub-system may include a dispensing hose coupled to the dispensing valve and a dispensing member coupled to the dispensing hose. The dispensing member may be configured to dispense the one or more polymeric materials contained within the pre-pressurized canister.

The invention discloses a gas-phase one-step preparation method of 2, 2, 2, 3-tetrafluoropropene, and belongs to the technical field of fluorine chemical industry. The method aims at solving the problems that in the prior art, the technological process is complex, selectivity is poor and cost is high. The method is characterized in that gas-phase 1, 1, 2, 3-tetrachloropropene and / or 1, 1, 1, 2, 3-pentachloropropane and gas-phase hydrogen fluoride are mixed and preheated, and the mixture is introduced into a reactor filled with a specific catalyst for a one-step fluorination reaction. By optimizing parameters such as a raw material molar ratio and reaction pressure and cooperating with separation and purification processes including removal of HCl by a light component tower, refining by a heavy component tower and water alkali washing, high conversion rate of the raw materials and high selectivity of the reaction are realized.

To provide a method for producing chlorofluorobutane (CFB) by dimerizing trichloroethylene (TCE) to generate chlorinated butadiene and fluorinating the hydrogen atoms of this chlorinated butadiene.　Trichloroethylene (TCE) is dimerized at a temperature of 100°C or more in the presence of a free radical generator using a dimer represented by formula (1) from TCE as a solvent. Hexachlorobutadiene (C4Cl6) is produced by chlorination and dehydrochlorination from the dimer, and the hexachlorobutadiene is fluorinated to produce chlorofluorobutane (CFB).

The present invention discloses a method for co-producing 3,3,3-trifluoropropene and 2,3,3,3-tetrafluoropropene, introducing 1,1,1,3-tetrachloropropane, 1,1,1,2,3-pentachloropropane and hydrogen fluoride into a first reactor to have a reaction in the presence of a first catalyst to obtain a reaction product of the first reactor; distilling the reaction product of the first reactor to obtain a 3,3,3-trifluoropropene product and a column bottom product, mixing the column bottom product with the hydrogen fluoride, and feeding a resulting mixture into a second reactor to have a reaction in the presence of a second catalyst to obtain a reaction product of the second reactor; and separating hydrogen chloride from the reaction product of the second reactor, and then carrying out water washing, alkali washing and drying to obtain a 2,3,3,3-tetrafluoropropene product. The present invention has the advantages of simple process, high efficiency, high operation flexibility, small investment and low energy consumption.

The invention discloses a preparation method of 1, 1, 2-trifluoroethane, and belongs to the field of fluorine-containing alkane preparation. According to the method, 1, 1-difluoro-2-chloroethane and anhydrous hydrogen fluoride are used as raw materials, iron powder is creatively used as a catalyst, and the pollution problem of a traditional chromium-based catalyst is solved by optimizing reaction conditions. The method is characterized in that the iron powder catalyst is subjected to organic solvent washing, vacuum drying and reduction activation pretreatment in the hydrogen atmosphere, and the catalytic efficiency is remarkably improved. Through a system purification process and a raw material circulation mechanism, the effects that the highest conversion rate of R142 is 75.28% and the highest selectivity of R143 is 91.83% are achieved, the method has the outstanding advantages of being environmentally friendly, low in cost and easy to industrialize, and a reliable scheme is provided for clean production of 1, 1, 2-trifluoroethane.

The invention belongs to the technical field of fluorine chemical industry, and particularly relates to a preparation method of cis-1, 1, 1, 4, 4, 4-hexafluoro-2-butene. Comprising the following steps: I, under an illumination condition, enabling 3, 3, 3-trifluoropropene to react with carbon tetrachloride, optionally in the presence of a first catalyst, so as to obtain 1, 1, 1, 3-tetrachloro-4, 4, 4-trifluorobutane; and II, the obtained 1, 1, 1, 3-tetrachloro-4, 4, 4-trifluorobutane and hydrogen fluoride are subjected to a reaction under the action of a second catalyst, and cis-1, 1, 1, 4, 4, 4-hexafluoro-2-butene is obtained. According to the method, in the first step, the addition reaction is driven by illumination, the production cost can be greatly reduced by a photocatalysis mode, and the reaction efficiency can be improved by matching with a special catalyst; the fluorination reaction in the second step is matched with an exclusive catalyst, so that the conversion rate of reactants and the selectivity of a target product can be effectively improved, and the high efficiency of the whole preparation process is guaranteed.

The invention relates to the technical field of protein electrophoretic separation, and particularly discloses a capillary electrophoretic separation gel material as well as a preparation method and application thereof. In the capillary electrophoresis separation gel material 12-n fluorododecyl lithium sulfate provided by the invention, n is equal to 1, 2 or 3. When being used in gel electrophoresis, the polymer is more stable than SDS under a high-temperature condition. Meanwhile, the 12-n fluorododecyl lithium sulfate capillary gel electrophoresis separation gel provided by the invention has good migration time consistency during long-time operation, and methodological detection shows that the gel has good repeatability. The capillary gel electrophoresis separation gel has very good repeatability, precision, linearity and accuracy indexes when being used for separating the polysaccharylation site fusion protein.

A process for preparing a fluorinating reagent from a calcium-containing compound is disclosed. The process bypasses the requirement to form hydrofluoric acid. The fluorinating reagent can be used to prepare high-value fluorochemicals.

The invention provides a method for co-producing HFO-1234yf and HFO-1234ze. The method comprises the following steps: (1) reacting dichloroethylene with trifluoromethane under the action of a first catalyst to prepare trifluorodichloropropane; (2) carrying out gas-phase dehydrochlorination reaction on the trifluorodichloropropane under the action of a second catalyst to generate trifluorochloropropene; and (3) the trifluorochloropropene and anhydrous hydrogen fluoride are subjected to a gas phase fluorination reaction under the action of a third catalyst, and HFO-1234yf and HFO-1234ze are generated. By optimizing a reaction path and a catalyst system, efficient co-production of HFO-1234yf and HFO-1234ze is realized, and the method has the advantages of mild reaction conditions, high product selectivity and the like, and is suitable for industrial production.

This invention discloses a method for preparing 2,3,3,3-tetrafluoropropylene, comprising reacting carbon tetrachloride with ethylene in the presence of a catalyst containing reduced iron powder and a co-catalyst, separating and purifying the reactants to obtain HCC-250fb; subjecting HCC-250fb to dehydrochlorination to generate HCC-1240za; reacting HCC-250fb with chlorine in a liquid-phase or gas-phase chlorination reaction to obtain HCC-240db; reacting HCC-240db with hydrogen fluoride in a gas-phase fluorination reaction to generate HCFO-1233xf; and reacting HCFO-1233xf with hydrogen fluoride in a gas-phase fluorination reaction in the presence of a supported or unsupported chromium oxide catalyst to generate HFO-1234yf. The method of this invention uses readily available raw materials, has low cost, and allows unreacted raw materials to be recycled for further reactions, resulting in minimal waste emissions.

To provide a fluorinating agent that can be produced using a simple method, and a fluorination method that uses a fluorinating agent that can be produced using a simple method.SOLUTION: The present disclosure provides a fluorinating agent that comprises a fluorine-containing compound and fluoride ions.SELECTED DRAWING: None

A process for producing E-1,1,1,4,4,4-hexafluorobut-2-ene comprises contacting 1,1,2,4,4-pentachlorobuta-1,3-diene with hydrogen fluoride in the vapor phase in the presence of a fluorination catalyst. A process for producing Z-1,1,1,4,4,4-hexafluorobut-2-ene further comprises contacting E-1,1,1,4,4,4-hexafluoro-2-butene with chlorine in the presence of a catalyst to produce 2,3-dichloro-1,1,1,4,4,4-hexafluorobutane, followed by reaction with base to produce 1,1,1,4,4,4-hexafluoro-2-butyne, and subsequently hydrogenating hexafluoro-2-butyne to produce Z-1,1,1,4,4,4-hexafluoro-2-butene.

This invention belongs to the field of fluorochemical technology, specifically relating to a method for preparing cis-1,1,1,4,4,4-hexafluoro-2-butene. The method includes the following steps: I. Reacting 3,3,3-trifluoropropylene with carbon tetrachloride under light irradiation, optionally in the presence of a first catalyst, to obtain 1,1,1,3-tetrachloro-4,4,4-trifluorobutane; II. Reacting the obtained 1,1,1,3-tetrachloro-4,4,4-trifluorobutane with hydrogen fluoride in the presence of a second catalyst to obtain cis-1,1,1,4,4,4-hexafluoro-2-butene. The first step of this method uses a light-driven addition reaction, and the photocatalytic approach significantly reduces production costs. It can also be combined with a dedicated catalyst to improve reaction efficiency. The second step, the fluorination reaction, is adapted to a specific catalyst, which can effectively improve the conversion rate of the reactants and the selectivity of the target product, ensuring the overall high efficiency of the preparation process.

A method of making chlorofluorohydrocarbons including, contacting, a fluorinated hydrocarbon reagent in the vapor phase, with hydrogen chloride (HCl). The reaction is conducted in the presence of an effective amount of a catalyst, at an elevated temperature sufficient to effect hydrochlorination to form a reaction mixture including a chlorofluorohydrocarbon.

The present invention relates to a process for the co-production of 1,1,1-trifluoropropene (HFO-1243zf) and E-1,1,1,4,4,4-hexafluoro-2-butene (E-1336mzz).

The invention discloses a synthesis method of 1, 1, 2, 2, 9, 9, 10, 10-octafluoro [2.2] dimer paraxylene, belonging to the technical field of organic chemical synthesis, comprising the following steps: (1) dissolving [2.2] dimer paraxylene in an inert solvent, and reacting with chlorine to obtain 1, 1, 2, 2, 9, 9, 10, 10-octachloro [2.2] dimer paraxylene; (2) dissolving the obtained 1, 1, 2, 2, 9, 9, 10, 10-octachloro [2.2] dimer p-xylene in an inert solvent, and reacting with hydrogen fluoride to obtain 1, 1, 2, 2, 9, 9, 10, 10-octafluoro [2.2] dimer p-xylene; the synthesis method has the advantages of cheap and easily available raw materials, simple reaction operation, high synthesis yield, good product purity, convenience in industrial application and the like.

Disclosed is a process for the synthesis of fluorinated olefins, and in particularly preferred embodiments tetrafluorinated olefins having F on an unsaturated, non-terminal carbon, such as 2,3,3,3-tetrafluoropropene. The preferred processes of the present invention in accordance with one embodiment generally comprise:(a) reacting a compound of formula (I)with a compound of formula (II)to produce a reaction product comprising a compound of formula (III)and(b) exposing said compound of formula (III) to reaction conditions effective to convert said compound of formula (III) to a compound of formula (IV)wherein X1, X2, and X3 are each independently selected from the group consisting of hydrogen, chlorine, bromine, fluorine and iodine, provided that X1 and X2 in formula (I) are not both hydrogen and Z is Cl, I, Br, or F.

The application discloses a preparation method of cis-1-chloro-2,3,3-trifluoropropene and belongs to the technical field of organic synthesis. The method is characterized in that: firstly, a mixed slurry is prepared by using a soluble aluminum salt, a soluble chromium salt, a soluble zinc salt, a surfactant and water as raw materials; the mixed slurry is dried, calcined and fluorinated to obtain a Cr / Al / Zn fluorination catalyst; and then, under the action of the Cr / Al / Zn fluorination catalyst, gas-phase fluorination reaction is carried out by using 1,1,2,3,3-pentachloropropane and hydrogen fluoride gas as reaction raw materials to obtain cis-1-chloro-2,3,3-trifluoropropene. The method is simple and efficient, the reaction is carried out under the action of a specific catalyst, the selectivity of the product is high, the conversion rate of the raw material is high, the method is green and environment-friendly, and less "three wastes" are generated.

Disclosed are processes for the production of fluorinated olefins, preferably adapted to commercialization of CF3CF=CH2 (1234yf). Three steps may be used in preferred embodiments in which a feedstock such as CCl2=CClCH2Cl (which may be purchased or synthesized from 1,2,3-trichloropropane) is fluorinated (preferably with HF in gas-phase in the presence of a catalyst) to synthesize a compound such as CFaCCI=CH2, preferably in a 80-96% selectivity. The CF3CCl=CH2 is preferably converted to CF3CFClCH3 (244-isomer) using a SbCl5 as the catalyst which is then transformed selectively to 1234yf, preferably in a gas-phase catalytic reaction using activated carbon as the catalyst. For the first step, a mixture of Cr2O3 and FeCl3 / C is preferably used as the catalyst to achieve high selectivity to CF3CCl=CH2 (96%). In the second step, SbCls / C is preferably used as the selective catalyst for transforming 1233xf to 244-isomer, CF3CFClCH3. The intermediates are preferably isolated and purified by distillation and used in the next step without further purification, preferably to a purity level of greater than about 95%.

The invention relates to a synthesis process of octafluorocyclobutane, which comprises the following steps: taking dichlorohexafluorocyclobutane and hydrogen fluoride as raw materials, adding a lewis acid substance antimony pentachloride or fluorocobaltate as a catalyst to catalyze the raw materials to react, generating octafluorocyclobutane through circular reaction, and then purifying and separating the generated octafluorocyclobutane. The catalyst used in the method is simple and easy to obtain, the temperature in the reaction process is low, energy consumption is low, and the whole technological process is easy to amplify. The problems that in the prior art, a catalyst for reaction is difficult to obtain, energy consumption is high due to high reaction temperature, and the process is complex and not easy to popularize and amplify are solved.