100 results about "Drug dosing" patented technology

Embodiments relate to device, system and methods for personalised drug dosing via a device, the device comprising a first chamber comprising a drug reservoir unit; a second chamber comprising an electronic unit comprising a control component; a third chamber comprising a drug delivery unit and a flow control component controlled via the electronic unit; wherein the device is fully implanted in a subject during its intended operational modes, and wherein the device releases a body temperature stable drug formulation into the subject at a flow rate such that a variation in the flow rate is within ±15% by volume.

The invention discloses an intelligent dosing system and method based on machine learning, and the method comprises the steps: S1, collecting fluidized bed operation parameters and water quality characteristic data in real time, including water flow dynamic parameters, water quality index parameters and particle morphology parameters, and constructing a time sequence characteristic database; s2, constructing a dynamic dosing model based on the fluidized bed by using data in the time sequence characteristic database, and performing joint prediction on the medicament type, the dosing amount and the operation parameters; s3, according to a prediction result output by the model, controlling the agent dosage, the agent concentration, the water flow speed and the aeration intensity; and S4, monitoring the fluidized bed and dosing control parameters in real time, and dynamically correcting the fluidized bed parameters in combination with the effluent turbidity of the fluidized bed and the particle sedimentation efficiency, so as to solve the problems that the sewage treatment effect in the prior art is poor, and medicament waste, substandard treatment and secondary environmental pollution are possibly caused.

The invention discloses an intelligent anesthesia depth regulation and control system based on a multi-modal biological signal, which relates to the technical field of anesthesia depth regulation and control and comprises a multi-modal biological signal acquisition module, a signal fusion processing module, an intelligent anesthesia depth analysis module, an intelligent regulation and control decision module and an intelligent control terminal. Multi-modal biological signals of a patient are collected in real time, multi-modal physiological signals such as electroencephalogram, electrocardio and blood oxygen are fused, intelligent analysis is performed in combination with a deep learning model and a fuzzy PID control algorithm, and in combination with a pharmacokinetic model, the individual difference of the patient can be considered, the anesthesia depth of the patient is accurately evaluated, and the accuracy of anesthesia is improved. Individual anesthetic dosage adjustment is completed, a basis is provided for accurate regulation and control of anesthetic, accurate closed-loop regulation and control of anesthesia depth are achieved, physiological changes of a patient can be responded in real time, the anesthetic dosage can be adjusted in time, and compared with a traditional manual regulation and control mode, the risk of knowing and excessive anesthesia in an operation can be reduced.

The invention relates to the technical field of water treatment, and provides a chemical adding control method and device in a water treatment process, a product and equipment. The method comprises the following steps: acquiring inlet water parameters, and determining a target water quality category to which the inlet water parameters belong according to an inlet water quality classification model; determining a first dosage prediction feature and a second dosage prediction feature corresponding to the target water quality category according to a preset mapping relation; inputting the characteristic value of the first dosage prediction characteristic into a dosage regression prediction model corresponding to the target water quality category to obtain a first dosage prediction value; inputting the characteristic value of the second dosage prediction characteristic into a dosage classification prediction model corresponding to the target water quality category to obtain a first dosage prediction grade; and according to the overlapping relationship between the first dosage predicted value and the first dosage predicted grade, determining a target dosage predicted value, and controlling the dosage in the water treatment process based on the target dosage predicted value. According to the scheme, the dosing prediction efficiency and accuracy can be improved.

The invention relates to the technical field of treatment of chronic diseases of old people, and discloses a metabolic characteristic-based medicine dosage optimization method for chronic diseases of old people. The method comprises the following steps: acquiring drug metabolism parameters (including a plasma concentration peak value, a half-life period curve and the like) and organ function data (including a hepatocyte metabolism rate, a glomerular filtration rate and the like) of a plurality of monitoring nodes, arranging the drug metabolism parameters and the organ function data into a time sequence input vector, and extracting a dynamic feature vector by using a time convolution network and an adaptive filter network; performing feature crossing, pharmacokinetic constraint correction and feature enhancement processing, performing fusion to generate a joint feature vector, inputting the joint feature vector into a dose decision model to obtain an adjustment coefficient, and generating a drug dose interval with a safety threshold in combination with a historical drug use record. According to the method, multi-dimensional data integration and dynamic modeling are realized, the accuracy and safety of chronic disease medication of old people are improved, and the method is suitable for individualized treatment.

A method and algorithm for dosing single and multiple drugs for an individual patient includes the step of collecting data from the individual patient. The data includes drugs to be taken by the patient, the patient's age, medical condition, metabolism, and other factors. The method further includes the steps of analyzing the individual patient data in view of dosing criteria established based on patient population data. Based on the analysis, a dose of the single or multiple drugs is recommended. Alternative treatment options can also be recommended.

A novel embodiment of a pump system, for example, of the type that would be used in a wearable drug delivery system, comprises dual linear-actuated plungers disposed in a pump chamber. The plungers are coupled to a leadscrew having both left-hand and right-hand threads such that rotation of leadscrew in a first direction moves the plungers together and rotation of leadscrew in a second, opposite direction moves the plungers apart. Movement of the plungers away from each other draws one or more doses of a liquid drug from a reservoir into the pump chamber, while movement of the plungers together forces liquid drug to a patient interface for delivery to the patient.

The invention relates to the technical field of sewage treatment, in particular to a sewage dosing treatment device and a use method. The upper side and the lower side of the medicine adding cylinder are provided with a notch used for medicine feeding and a material opening used for medicine discharging correspondingly. The swinging mechanism is arranged on the medicine adding cylinder; the shaking assemblies are arranged at the two ends of the medicine adding cylinder and used for shaking the medicine discharging frame to discharge the medicine; and the dispersing mechanism is arranged in the medicine outlet frame and used for dispersing the medicines. Through the arrangement of the swing mechanism, the shaking assembly and the dispersing mechanism, the efficient process of adding a chemical into the chemical adding cylinder and uniformly dispersing the chemical into sewage is achieved, the common problems of chemical caking and uneven distribution in a traditional chemical adding method are effectively solved through a series of operations, and in addition, through a continuously-running spiral stirring paddle, the chemical adding efficiency is improved. The medicament is further prevented from being gathered in the medicament adding cylinder, the good flowability of the medicament is ensured, and the use efficiency of the medicament and the overall effect of sewage treatment are remarkably improved.

A computer-implemented method for treating a patient suffering from Type I Diabetes (T1D). The method can include quantifying physical activity (PA) of the patient; calculating an accumulated PA periodically based on the quantified PA, the accumulated PA indicating an aggregate of the PA; and generating an activity informed insulin bolus by adjusting a prevalent functional insulin therapy bolus with a previous activity component, wherein the previous activity component is based on the accumulated daily PA, an activity profile, and an activity factor of the patient. The method can include determining an additional glucose uptake within a time period, the additional glucose uptake being caused by a PA; translating the additional glucose uptake into a number of insulin units with a same BG lowering impact; and generating an activity informed insulin bolus by adjusting a prevalent functional insulin therapy bolus with the insulin units.

The invention relates to the technical field of water treatment, and provides a chemical adding control method and device in a water treatment process, a product and equipment. The method comprises the steps that characteristic values of dosage prediction characteristics in the water treatment process are obtained, and the dosage prediction characteristics comprise floc characteristics, water inlet parameter characteristics and water outlet parameter characteristics; inputting the characteristic value of each dosage prediction characteristic into a dosage regression prediction model taking the dosage prediction characteristic as single input to obtain a first dosage prediction value corresponding to each dosage prediction characteristic; inputting the characteristic value of each dosage prediction characteristic into a dosage classification prediction model taking the dosage prediction characteristic as single input to obtain a first dosage prediction grade corresponding to each dosage prediction characteristic; and controlling the dosage in the water treatment process based on the first dosage prediction value and the first dosage prediction grade corresponding to each dosage prediction feature. The control accuracy of the dosage can be improved.

The invention discloses a vitamin K3 oxidation waste liquid recovery device based on glucose reduction, and relates to the technical field of waste liquid recovery, the recovery device comprises a tank body, a stirring device, a detection device, a comparison device, a medicament adding pipe, a glucose adding pipe and a waste liquid adding pipe, the tank body is connected with the stirring device, the tank body is connected with the detection device, and the tank body is connected with the comparison device. The tank body is connected with the comparison device, the comparison device is connected with the stirring device, the tank body is communicated with the agent feeding pipe, the tank body is communicated with the glucose feeding pipe, the tank body is communicated with the waste liquid feeding pipe, the comparison device is connected with the agent feeding pipe, the stirring device is arranged in the tank body, the detection devices and the comparison devices are arranged on the tank body, and a discharging pipe is arranged on the tank body. And the detection device is connected with the medicament adding pipe and the comparison device.

The invention provides an optimal administration method for promoting cervical maturation by misoprostol based on a PopPK model, and belongs to the technical field of drug administration scheme optimization, the method comprises the following steps: constructing the PopPK model for oral administration of misoprostol by a pregnant woman in late pregnancy, the PopPK model is a model structure containing absorption lag time zero-order-first-order absorption parallel, one-atrioventricular distribution and first-order elimination, and the PopPK model is a model structure containing absorption lag time zero-order-first-order absorption parallel, one-atrioventricular distribution and first-order elimination; the PopPK model comprises two absorption chambers and one central chamber; and based on the PopPK model, determining a staged administration scheme through simulation optimization. The limitation of a traditional fixing scheme is effectively overcome, and the safety, effectiveness and clinical practicability of drug administration are considered.

The utility model relates to the technical field of medicines, and proposes a quantitative packaging device for liquid medicines, comprising: a workbench, a first motor is installed at the inner bottom end of the workbench, a lifting component is arranged at the upper end of the workbench for lifting a packaging box, a placing component is arranged at the front end of the lifting component for placing and fixing the packaging, a fixing seat is arranged at the upper end of the lifting component, a feeding component is arranged at the center of the fixing seat for storing and filling medicines, a cleaning component is arranged at the upper end of the fixing seat for cleaning the feeding component, so that the mouth of the packaging box is flush with the lower liquid port, the liquid splashing caused by the position deviation of the packaging box is reduced, the position accuracy of the packaging box is ensured, thereby reducing the filling cost, and then the liquid medicine is measured by a graduated tube to ensure the fixed volume of the filling liquid, thereby improving the working efficiency of the device.

The invention provides a precise dosing method and system based on an intelligent valve, and relates to the technical field of intelligent control, and the method comprises the steps: collecting multi-source sensor data of a dosing system in real time; preprocessing the data of the multi-source sensor, and outputting standardized process parameters; based on the standardized process parameters, the deviation between a dosing flow measured value and a set value is calculated; when the deviation exceeds a preset threshold value, a valve opening control quantity is generated according to a PID control algorithm and a water inlet flow-dosing flow mapping model, and feedforward compensation is carried out in combination with a water inlet flow variable quantity; and outputting a valve opening control signal and a dosing pump frequency control signal, and driving an execution mechanism to adjust the dosage of the medicament. According to the precise dosing method and system provided by the invention, through high-precision hardware and an intelligent algorithm, the operation cost and the manual dependence are remarkably reduced, and the harsh requirements of the high-end manufacturing industry and the water environment treatment field on precise control are met.

The utility model discloses an intelligent automatic dispensing and dosing system, the dispensing mechanism of which includes a medicine powder feeding component and a medicine dissolving component, the medicine powder feeding component is connected to the medicine dissolving component to fully dissolve the medicine powder; the dosing pump is connected to the medicine dissolving component through a medicine feeding pipe, and is connected to the sewage inlet pipe through a dosing pipe; the water inlet detection component includes an online suspended matter measuring instrument and an electromagnetic flowmeter fixedly arranged on the sewage inlet pipe; the water outlet detection component includes a water outlet turbidity measuring instrument fixedly arranged on the water production pipe; the controller adopts a PLC controller, and each component and instrument are electrically connected to the PLC controller, thereby realizing linkage control of each component or instrument. The intelligent automatic dispensing and dosing system of the utility model can automatically dispense medicine, reduce manual operation, and reduce the workload of operation and maintenance; it can also automatically adjust the dosage to effectively ensure the adaptability of the dosage, which can prevent the waste of medicines and ensure the quality of effluent water.

The invention relates to the field of control, in particular to an infusion pump drug dosage control method and system fusing clinical decision support, and the method comprises the steps: monitoring at least two physiological parameters in real time, including a main treatment index and a side effect precursor index; for each parameter, calculating the parameter credibility based on the parameter signal fluctuation characteristic and the deviation degree of the parameter signal fluctuation characteristic and the predicted value of the PK-PD model, and during state updating, weighting the monitoring data by using the parameter credibility to correct the state of the patient; in the constraint conditions, a multi-dimensional safety state space formed by the main treatment indexes and the side effect precursor indexes is defined, and boundaries are adjusted according to the credibility of the side effect precursor indexes; in the cost function, the length of a prediction time window and the asymmetric penalty weight of a prediction track deviating from a target are adjusted according to the credibility of main treatment indexes, a model prediction control problem is solved to obtain an optimal administration dosage sequence, and a first control instruction is output to an infusion pump to be executed.

A system for medicament infusion may include an infusion pump and a mobile device associated with a user. The mobile device is configured to determine an online dosing model and an offline model. The infusion pump is configured to determine an operation mode of the infusion pump based on a connection status between the mobile device and the infusion pump. The operation mode comprises an online mode when the infusion pump is connected to the mobile device and an offline mode when the infusion pump is not connected to the mobile device. The infusion pump is also configured to deliver a dose of medicament to the user based on the online dosing model or the offline dosing model, in accordance with a determination that the infusion pump is in an online mode or an offline mode.

The invention relates to the technical field of sewage treatment equipment, in particular to an intelligent chemical feeding type sewage treatment device which comprises a machine body, a chemical feeding hopper arranged on the machine body and a protective shell arranged on the top of the machine body, a rotating cylinder is movably arranged in the machine body, and a connecting rod is arranged on the side face of the machine body. The reverse wave assembly is arranged in the machine body, an arc-shaped wiping plate extends at a connecting rod and is completely attached to the inner wall of a medicine dissolving cavity, the connecting rod and the arc-shaped wiping plate are driven by a rotating cylinder to rotate, meanwhile, a wave motion trail is generated, and therefore the wiping range is enlarged; according to the intelligent dosing type sewage treatment device, common liquid medicine can be efficiently stirred under the conventional condition through the configured rotating speed switching unit, the number of driving sources is reduced through the integrated design, the equipment structure is optimized, the use space is remarkably saved, and meanwhile the operation convenience and the overall efficiency of the equipment are improved.

The invention provides an intelligent dosing system for a sewage treatment plant, and relates to the technical field of sewage treatment, the intelligent dosing system comprises a control cabinet, a dismounting structure, an adjusting structure and a pipeline, and one side of the control cabinet is provided with a display screen. The device has the advantages that the water pump can be conveniently and quickly mounted and dismounted, regular inspection of the water pump can be facilitated, the water pump can be quickly repaired or replaced when damaged or broken down, the maintenance cost of the water pump is greatly reduced, the maintenance and overhaul time can be remarkably shortened by quickly mounting and dismounting the water pump, the downtime is shortened, and the maintenance efficiency is improved. For sewage treatment facilities, the overall operation efficiency can be improved, it is ensured that the equipment operates for a long time as far as possible and is not affected by faults, impurities or sediments may be accumulated in the water pump in the sewage treatment process, and regular cleaning of the water pump is crucial for keeping normal operation of the water pump. And the water pump can be conveniently disassembled and cleaned through the quick disassembly and assembly design, so that the effects of reducing equipment abrasion and prolonging the service life are achieved.

The utility model provides a large-area uniform liquid injection device, which comprises a medicine feeding funnel and a plurality of medicine feeding pipelines, the upper ends of the plurality of medicine feeding pipelines are communicated with the medicine feeding funnel, and the lower ends of the medicine feeding pipelines are connected with liquid separation and medicine injection ports. Compared with the prior art, by means of the large-area uniform liquid injection device in the scheme, liquid medicine can be rapidly and uniformly mixed and covers the polar plate in a large area.

The present invention discloses a drug inhalation device. The inhalation device includes a drug dosing chamber, a push button, and a suction nozzle. The drug dosing chamber includes at least one drug dosing chamber body, which has drug dosing side walls and a drug dosing bottom surface, forming a capsule-receiving cavity. The drug dosing side walls have an inner surface and an outer surface, and the inner surface has a curvature. The drug dosing side walls are provided with at least two drug dosing air channels, each having a first air channel side wall and a second air channel side wall. The first air channel side wall is disposed opposite the second air channel side wall, the first air channel side wall is tangent to the inner surface, and the angle between the second air channel side wall and the first air channel side wall is 1 to 10 degrees. The push button includes a push button body and a puncture unit. The puncture unit is connected to the push button body and can enter the capsule-receiving cavity to puncture the drug capsule. The suction nozzle includes a suction nozzle channel, which is connected to the capsule-receiving cavity and the drug dosing air channel. This inhalation device can reduce the resistance when a user inhales drug powder.

The application provides a misoprostol cervical ripening optimization dosing method based on a PopPK model, belongs to the technical field of drug dosing scheme optimization, and comprises the following steps: constructing a PopPK model of oral misoprostol for pregnant women in the third trimester of pregnancy, the PopPK model is a model structure containing zero-order-first-order absorption in parallel, one-compartment distribution and first-order elimination, the PopPK model comprises two absorption compartments and one central compartment; and determining a phased dosing scheme based on the PopPK model through simulation optimization. The method effectively overcomes the limitations of traditional fixed schemes, and takes into account the safety, effectiveness and clinical practicability of dosing.

The invention provides an intelligent dosing system, and relates to the field of water treatment. The intelligent dosing system comprises a main pipeline, the main pipeline is sequentially connected with a mixing cavity, a detection cavity and a circulating backflow cavity, a detection unit for detecting liquid numerical values is arranged in the detection cavity, one end of the mixing cavity is in one-way connection with an injection cavity, and the other end of the mixing cavity is in one-way connection with a circulating backflow cavity. And the injection cavity is connected and communicated with a reagent quantitative unit for quantitatively adding and adjusting a detection value. According to the intelligent dosing system, parameters of ultrapure water in the main pipeline are detected by virtue of the detection unit, a specified reagent is correspondingly fed, so that the detection value of the ultrapure water meets the requirement, the circulating reflux cavity and the mixing cavity are communicated by virtue of the circulating pump through closing the electromagnetic tee joint I and the electromagnetic tee joint II, and the ultrapure water circularly flows; and the first electromagnetic tee joint and the second electromagnetic tee joint are opened in an equal ratio, so that the ultrapure water mixed with the reagents can be gradually and uniformly discharged to a main pipeline, and the effect of adjusting the ultrapure water in a segmented manner is achieved.

The present invention provides a self-learning slow-release scale inhibitor dosing method. By continuously measuring and statistically analyzing the environmental indicators in the circulating water, the optimal dosing amount calculation method under corresponding conditions is given. At the same time, through software programming, the dosing equipment gives a real-time dosing amount adjustment scheme for circulating water with different conditions. Meanwhile, the dosing equipment is endowed with a self-learning function through statistics. It solves the problem in the prior art that the dosing amount cannot be controlled according to the actual water quality situation and equipment requirements. It realizes the function of dosing different dosages of drugs corresponding to different water quality situations and equipment materials, solves the problems of excessive drug waste and insufficient drug dosing affecting the service life of the equipment, and achieves the effects of saving water and increasing the service life of the equipment. It has advantages such as environmental protection, energy conservation, and water conservation.

Cardiopulmonary resuscitation demands rapid and precise responses, particularly in hospital emergency departments. The "Automated Resuscitation Trolley Alert and Drug Dosage System" is designed as an add-on compatible with various resuscitation trolleys. The system features a powerful central processing unit, a liquid-resistant capacitive touchscreen, an audio-visual alert system with high-power LEDs, and communication modules for hospital network integration. It uses artificial intelligence and machine learning algorithms to calculate drug dosages based on patient information and monitoring data. The audio-visual alert system reduces medical team response times in emergencies. Connectivity to hospital information systems enables quick access to patient data and automatic logging of actions. By enhancing precision and speed in drug administration, minimizing human errors, and improving team coordination, this invention significantly improves the quality of emergency services and the success rate of resuscitation procedures.

The present invention provides a solid water treatment chemical dosing device and its application method. The dosing device is provided with chemical dosing ports corresponding to each chemical storage tank on the chassis, and by rotating the chassis, the chemical dosing ports are connected to the water inlet of the water tank arranged on the water treatment system pipeline, solving the problem of drug dosing in the sealed section of the water treatment system; the chemical storage tank is connected to the water inlet of the water tank through the chemical dosing port, facilitating the inflow of water into the chemical storage tank to dissolve the chemical, solving the problem of incomplete dissolution of the chemical; through a plurality of chemical storage tanks circumferentially arranged on the chassis, at the same time, by rotating the chassis and using the sliding end of the elastic sliding limiting member to enter the limiting groove to determine the connection between the chemical dosing port corresponding to the required chemical storage tank and the water inlet on the water tank, such operation can meet the requirements of different chemical dosing amounts in multiple dosing cycles, greatly improving the dosing efficiency. The application method has simple steps and convenient operation.

The invention relates to the technical field of medical instruments, in particular to a medical medicine quantitative infusion device which comprises an intravenous needle, a Luer taper liquid medicine filter, a bottle stopper puncture outfit, a Murphy type drip chamber, an infusion hose and a flow rate adjusting mechanism. An automatic liquid stopping mechanism is arranged in the Murphy type drip chamber and comprises a cylindrical shell fixedly connected to the inner bottom wall of the Murphy type drip chamber. By arranging the flow speed adjusting mechanism, the abutting arc block can be driven to stably move along the guide rod by rotating a flow speed adjusting knob, an infusion hose is accurately extruded to change the diameter of a pipeline, fine adjustment of the infusion flow speed of liquid medicine is achieved, and compared with a traditional speed regulator, the self-locking characteristic is better; the problem that the infusion speed is too high or too low due to poor stability of a speed regulator is effectively solved, the infusion speed can be flexibly set according to the medicine type, the illness state of a patient and the tolerance degree, the accuracy of the medicine infusion dosage and speed is guaranteed, and the medicine treatment effect is improved.

An approach to supplementing or replacing at least one of a prescribed pharmaceutical can include receiving a usage agreement, executed by at least one of the subject or a medical professional, to use an inert substance according to a treatment regimen. A name or description of at least one health improvement product or protocol can be received, as well as an indication of a downtitration of the pharmaceutical. A treatment regimen can be determined, including an administration of the inert substance to the subject following the downtitration, including notifying the subject that the inert substance is not pharmacologically active.

The utility model discloses a dosing device for shutdown protection liquid, and relates to a dosing device; it comprises a main water inlet pipe, a shutdown protection liquid soluble medicine box and a multi-stage centrifugal pump; the main water inlet pipe is provided with a main water inlet valve, and is divided into an upper water inlet pipe and a lower water inlet pipe after the main water inlet valve; the top of the shutdown protection liquid soluble medicine box is connected with the upper water inlet pipe, the bottom of the shutdown protection liquid soluble medicine box is provided with a lower medicine outlet pipe of the soluble medicine box, and the lower medicine outlet pipe of the soluble medicine box is connected with the lower water inlet pipe and then connected to the multi-stage centrifugal pump; a Y-type filter is provided at the inlet of the multi-stage centrifugal pump, and a lower water inlet pipe ball valve is provided at the lower water inlet pipe; the shutdown protection liquid soluble medicine box is provided with an overflow pipe, and the overflow pipe is connected with a sewage pipe; the outlet of the multi-stage centrifugal pump is connected with the outlet pipe of the multi-stage centrifugal pump, and a pressure gauge, a check valve and a float flowmeter are provided on the outlet pipe of the multi-stage centrifugal pump in sequence; the utility model solves the problems of dosing time and inconvenient operation of the existing dosing device.

A system for medicament infusion may include an infusion pump and a mobile device associated with a user. The mobile device is configured to determine an online dosing model and an offline model. The infusion pump is configured to determine an operation mode of the infusion pump based on a connection status between the mobile device and the infusion pump. The operation mode comprises an online mode when the infusion pump is connected to the mobile device and an offline mode when the infusion pump is not connected to the mobile device. The infusion pump is also configured to deliver a dose of medicament to the user based on the online dosing model or the offline dosing model, in accordance with a determination that the infusion pump is in an online mode or an offline mode.