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185 results about "Drug powder" patented technology

The word cocaine refers to the drug in a powder form or crystal form.1 The powder is usually mixed with substances such as corn starch, talcum powder and/or sugar or other drugs such as procaine (a local anesthetic) or amphetamines.

Automatic quantitative charging device for chemical powder

The invention relates to the technical field of medicine production, and particularly discloses an automatic quantitative chemical medicine powder charging device which comprises a rack, a fixedly-connected storage assembly is arranged on the rack and provided with a hopper-shaped bin, a discharging barrel is arranged at the lower end of the hopper-shaped bin, a discharging rod is arranged in the hopper-shaped bin, and the hopper-shaped bin is provided with a discharging opening. A material blocking assembly fixedly connected with the rack is arranged at the discharging end of the discharging barrel, a quantifying assembly fixedly connected with the rack is arranged below the material blocking assembly, and a discharging hopper connected with the rack is arranged below the discharging end of the material containing component. Through accurate control over quantitative discharging of the material storage assembly, a blocking and collecting mechanism of the material blocking assembly on the medicine powder, weight monitoring of the subpackaged medicine powder of the quantitative assembly and linkage control over the opening and closing plate through the opening and closing component and the transmission component, the medicine powder subpackaging accuracy and efficiency are effectively improved, and meanwhile the medicine powder loss is reduced.
Owner:贵州博林药业有限公司

Full-automatic medicine powder packaging system based on drying and method thereof

The invention relates to the technical field of medicine powder packaging, and discloses a full-automatic medicine powder packaging system based on drying and a method thereof.The full-automatic medicine powder packaging system comprises a conveying unit, a stacking structure, a bagging machine, a tying machine, filling equipment and a cylinder hoop mounting structure; the barrel conveying device is responsible for conveying barrels needed in the medicine powder packaging process to different working stations. The stacking structure is located on one side of the conveying unit, a barrel to be filled is placed on the conveying unit, the bagging machine is located on one side of the conveying unit, and a packaging bag is arranged in the barrel in a sleeved mode. The size and the shape of the packaging bag are required to be accurate, the bag can completely cover the barrel, wrinkles or gaps are avoided, and medicine powder leakage is avoided. And the filling equipment is positioned on the opposite side of the bagging machine and is used for filling the medicinal powder into the bagged barrel body. The tying machine is located on the opposite side of the filling equipment and seals the packaging bag after filling of the medicine powder is completed. And the cylinder hoop mounting structure is mounted beside the tying machine and is responsible for mounting the cylinder hoop on a sealed package.
Owner:NANJING SHANGJING ZHIZAO TECH CO LTD

A single dose disposable powder aerosol device

A single dose disposable powder aerosol device belongs to the field of medical devices. It is composed of a bottom cover, a suction nozzle and a sliding cover. The suction nozzle and the sliding cover are assembled on one side of the bottom cover. The suction nozzle is assembled on the front half of the bottom cover, and the sliding cover is assembled on the rear half of the bottom cover. An air inlet, a medicine pit, a medicine inlet channel and a vortex cavity are sequentially arranged on the bottom cover. At least one side air inlet is arranged on the side of the vortex cavity. An ascending air duct and a medicine outlet are sequentially arranged in the suction nozzle body. After the bottom cover, the suction nozzle and the sliding cover are assembled into one, the air inlet, the medicine pit, the medicine inlet channel, the vortex cavity, the ascending air duct and the medicine outlet form a complete flow channel cavity. The filling operation of the medicine powder in the medicine pit is realized through three steps of sliding the sliding cover, loading the medicine powder and closing the sliding cover. The sliding cover structure is adopted, which is convenient for the filling operation or supplement of the built-in medicine powder, and can be switched between disposable and reusable types. It can be widely used in the design and manufacture field of inhalation type drug delivery devices.
Owner:SHANGHAI CHENPON PHARMA TECH

Interlocking powder collecting device

The utility model discloses an interlocking powder collecting device which comprises a powder container, an upper valve and a lower valve, the upper valve and the lower valve are arranged at the two ends of the powder container respectively, and the upper valve and the lower valve are connected to an interlocking control circuit. The interlocking control circuit is used for controlling the lower valve to be opened only when the upper valve is closed, and the lower valve continues to be opened for a first preset time so that powder can fall out of the powder container. And the control module is used for controlling the upper valve to be opened for a second preset time only when the lower valve is closed, so that the powder falls into the powder container from the upper side. According to the interlocking powder collecting device, on the basis that manpower is not needed and the cost is reduced, rapid and automatic powder collecting can be achieved, external air can be prevented from entering pharmaceutical equipment, medicine powder is prevented from being polluted, and the high quality of medicine is guaranteed.
Owner:惠利现代(安徽)智能装备有限公司

Rotating mechanism, dosage protection mechanism, breath triggering apparatus, and dry powder inhaler

PCT designated stage expiredWO2025139325A1InhalatorsPowder InhalerRespiratory triggering
Provided are a rotating mechanism (2), a dosage protection mechanism (3), a breath triggering apparatus (100), and a dry powder inhaler (800). The rotating mechanism (2) is applied to the breath triggering apparatus (100), and the rotating mechanism (2) comprises: a rotating shaft (22), an outer side surface of which is provided with a notch (221); and a baffle (21) connected to the outer side surface of the rotating shaft (22), wherein the rotating mechanism (2) is rotatable between a first position and a second position, and when in the first position, blocks a first airflow channel of the breath triggering apparatus (100); when moving from the first position to the second position, the baffle (21) rotates around the rotating shaft (22) to open the first airflow channel. By means of the above configuration, the problem of inadequate drug powder deaggregation in the prior art can be effectively resolved.
Owner:TRANSPIRE BIO INC +1

Preparation process for improving filling quality of Xinan capsule

The invention relates to the technical field of medicine capsule production, and particularly discloses a preparation process for improving the filling quality of a Xinan capsule, which comprises the following six steps: weighing 4-5kg of hawthorn leaf extract powder and 0.5 kg of corn starch, then taking 95% ethanol, preparing a soft material, granulating, drying, crushing, adding auxiliary materials during total mixing, and filling. The auxiliary materials for improving the flowability of the medicine powder are added into the crushed medicine powder, and the auxiliary materials are mixed to cover the surface of the powder to form a hydrophobic layer and directly block water contact, so that the flowability of the medicine powder is realized, the difference between the medicine loading amount and the standard amount can be very small during filling, and the safety of the prepared capsule medicine is ensured.
Owner:GUIZHOU GUANGZHENG PHARM CO LTD

An intelligent automatic dispensing and dosing system

The utility model discloses an intelligent automatic dispensing and dosing system, the dispensing mechanism of which includes a medicine powder feeding component and a medicine dissolving component, the medicine powder feeding component is connected to the medicine dissolving component to fully dissolve the medicine powder; the dosing pump is connected to the medicine dissolving component through a medicine feeding pipe, and is connected to the sewage inlet pipe through a dosing pipe; the water inlet detection component includes an online suspended matter measuring instrument and an electromagnetic flowmeter fixedly arranged on the sewage inlet pipe; the water outlet detection component includes a water outlet turbidity measuring instrument fixedly arranged on the water production pipe; the controller adopts a PLC controller, and each component and instrument are electrically connected to the PLC controller, thereby realizing linkage control of each component or instrument. The intelligent automatic dispensing and dosing system of the utility model can automatically dispense medicine, reduce manual operation, and reduce the workload of operation and maintenance; it can also automatically adjust the dosage to effectively ensure the adaptability of the dosage, which can prevent the waste of medicines and ensure the quality of effluent water.
Owner:TIANJIN HUAXIA YITAI ENVIRONMENTAL ENG CO LTD

Methimazole pulvis or powder and preparation method therefor

The present disclosure relates to a methimazole pulvis or powder and a preparation method therefor. By means of combining a solid dispersion technique with a micronization modification and secondary crushing process, a drug powder with a high dispersity is prepared, so that the specific surface area of the drug is increased, the dissolution rate of the drug is increased, the absorption rate is increased, and the bioavailability is improved. Other sweetening agents are also added to a preparation, a methimazole pulvis or powder which can be directly administrated and completely covers the bitter taste and the peculiar smell of the drug is prepared, and the drug can be administrated without water.
Owner:BEIJING MERSON PHARMA CO LTD

Dustproof tabletting device for pharmacy

The utility model discloses a dustproof tabletting device for pharmacy, which belongs to the technical field of tabletting devices and comprises a processing table, and a rotary tablet press body is mounted at the top of the processing table. The protective assembly comprises a transparent protective cover; by arranging the protection assembly, the rotary tablet press is simple in structure, convenient to use and practical, the rotary tablet press body can be isolated from external air, medicine powder is prevented from polluting the processing environment, and damage to the body health of operators is also prevented; the rotary tablet press is simple in structure and convenient for operators to maintain the rotary tablet press body, medicine powder can be collected into a dust collection cloth bag by arranging a dust removal assembly, accumulation of the medicine powder on the surface of the rotary tablet press body is reduced, and the operators can conveniently collect and reuse the residual medicine powder.
Owner:JIANGSU VANGUARD PHARM CO LTD

Pharmaceutical powder conveying pipeline convenient to clean

The utility model relates to the technical field of pharmacy, and particularly discloses a pharmaceutical powder conveying pipeline convenient to clean, which comprises a pipeline body, an auxiliary mechanism is arranged on the arc surface of the pipeline body, the auxiliary mechanism comprises a concave hole formed in the arc surface of the pipeline body, and a cover plate is arranged on the inner wall of the concave hole. A water pipe is installed on the surface of the cover plate, the arc surface of the water pipe communicates with a plurality of spray heads, the ends, away from the water pipe, of the multiple spray heads penetrate through the cover plate, two clamping holes are formed in one end of the pipeline body, and clamping rods are slidably inserted into the inner walls of the two clamping holes. By using the spray head, cleaning liquid can be sprayed into the pipeline body, so that residual medicine powder on the inner wall of the pipeline body can be removed, the cover plate can be disassembled and assembled by means of mutual clamping of the clamping hole and the clamping rod, and therefore a worker can conveniently clean the inner wall of the pipeline body after cleaning the inner wall of the pipeline body. And water stains in the pipeline body can be wiped.
Owner:HEFEI HUIXU METAL PROD CO LTD

Medicine powder delivery device and medicine bottle thereof and bottle cap of medicine bottle

A medicine powder delivery device and a medicine bottle thereof and a bottle cap of the medicine bottle are disclosed. The medicine powder delivery device includes a medicine bottle and a gas supply member. The medicine bottle has a bottle body and a bottle cap. The bottle body is filled with a medicine powder. When the bottle body is inverted, the bottle body has an unfilled space that is not filled with the medicine powder. The bottle cap includes a cap body, a medicine delivery tube, and a gas delivery tube. The cap body covers the bottle body. The medicine delivery tube and the gas delivery tube extends into the cap body. The medicine delivery tube communicating with the bottle body the gas delivery tube inserted into the unfilled space of the bottle body. The gas supply member is connected to the gas delivery tube.
Owner:ENDO-PEACE MEDICAL

Inhalation device for medication

ActiveCN115487386BMedical devicesInhalatorsDrug capsuleDrug dosing
The present invention discloses a drug inhalation device. The inhalation device includes a drug dosing chamber, a push button, and a suction nozzle. The drug dosing chamber includes at least one drug dosing chamber body, which has drug dosing side walls and a drug dosing bottom surface, forming a capsule-receiving cavity. The drug dosing side walls have an inner surface and an outer surface, and the inner surface has a curvature. The drug dosing side walls are provided with at least two drug dosing air channels, each having a first air channel side wall and a second air channel side wall. The first air channel side wall is disposed opposite the second air channel side wall, the first air channel side wall is tangent to the inner surface, and the angle between the second air channel side wall and the first air channel side wall is 1 to 10 degrees. The push button includes a push button body and a puncture unit. The puncture unit is connected to the push button body and can enter the capsule-receiving cavity to puncture the drug capsule. The suction nozzle includes a suction nozzle channel, which is connected to the capsule-receiving cavity and the drug dosing air channel. This inhalation device can reduce the resistance when a user inhales drug powder.
Owner:TAIAN DALU MEDICAL INSTR CO LTD

Medicine taking reminding device facilitating medicine storage

The utility model discloses a medicine taking reminding device convenient to store medicine, which comprises a device main body, a display screen is arranged on the upper surface of the device main body and located in the front, keys are arranged on the upper surface of the device main body and located on one side of the display screen, and a medicine box is embedded in the rear end of the device main body. The surface of the medicine box is movably sleeved with a scraping sleeve, and a positioning piece is embedded in the upper surface of the scraping sleeve. According to the medicine taking reminding device facilitating medicine storage, after tablets in the medicine box are eaten up, the medicine box is taken out of the embedded groove, then the positioning piece is pulled upwards, the lower end of the positioning rod of the positioning piece is pulled out of the positioning groove of the medicine box, at the moment, the medicine box can be pushed, and the medicine box can be taken out conveniently. Due to the fact that the scraping sleeve can scrape and sweep the inner surface of the medicine box in the pushing process of the medicine box, medicine powder on the inner surface of the medicine box can be conveniently cleaned, and only part of the medicine powder attached to the surface of the scraping sleeve in the scraping and sweeping process needs to be cleaned.
Owner:CHINESE PEOPLES ARMED POLICE FORCE ANHUI PROVINCIAL CORPS HOSPITAL

Inhalation device

ActiveCN115137925BMedical devicesInhalatorsPharmacy medicineInhaled drug
The present application discloses an inhalation device, which reduces the difficulty and cost of production while ensuring the use effect through a simplified structure; in the inhalation device of the present application, the filter element is tightly fitted with the capsule insertion port, and when the suction nozzle and the cover plate are engaged, the entire screen portion is located in the capsule compartment, so that when inhaling drug powder, the airflow can better pass through the screen portion under the action of negative pressure to produce an ideal flow direction, thereby ensuring effective inhalation of the drug powder.
Owner:CF PHARMTECH INC

Powder dispenser with anti-blocking function

This utility model discloses a powder delivery device with anti-clogging function, including a gun body, a nozzle, and a hose. A three-way valve and a ball valve core are installed inside the nozzle. The three-way valve has A-connector, B-connector, and C-connector. The A-connector is connected to an air tube located inside the gun body, and the B-connector is connected to the hose. A drug storage bottle is vertically mounted at the top of the nozzle, and a meandering pipe at the bottom of the drug storage bottle is connected to the C-connector. This allows the three-way valve to have two states: air supply and drug delivery. In the air supply state, it prevents drug powder from accumulating and clogging the drug storage bottle outlet, improving drug delivery efficiency; in the drug delivery state, it prevents backflow at the end of the delivery tube.
Owner:CHENGDU JITAI MEDICAL DEVICES CO LTD

A dry powder inhaler with a rotating multi-capsule channel that sequentially opens for inhalation

The present invention belongs to the technical field of medical devices, and particularly relates to a dry powder inhalation device with a rotating multi-capsule channel that is sequentially opened for inhalation, which is mainly used for administering in the form of a dry powder inhalant, and includes: a mouthpiece; a housing, a chamber is formed inside the housing; a plurality of capsule compartments are formed in the chamber and can be communicated with the mouthpiece; a diversion part is movably arranged between the mouthpiece and the plurality of capsule compartments to communicate the mouthpiece with one capsule compartment; a driving part is connected to the housing and the diversion assembly, and the driving part can rotate relative to the housing to drive the diversion assembly to move between the mouthpiece and the plurality of capsule compartments, so that different capsule compartments are communicated with the mouthpiece, solving the problem that: in the existing multi-capsule powder inhaler, when the user inhales the drug through the mouthpiece, the mouthpiece is communicated with each capsule compartment, resulting in the user's suction being dispersed into each capsule compartment, making it difficult for the user to inhale the drug, and thus reducing the inhalation efficiency.
Owner:HANGZHOU XIXI PHARM

A rumen-exposed guanidinoacetic acid granulation, coating, and drying integrated machine

This invention relates to the field of pharmaceutical manufacturing technology, specifically to an integrated machine for rumen-treated guanidinoacetic acid granulation, coating, and drying. It includes a positioning component, with a first processing device fixedly mounted on the left front end of the positioning component, and a second processing device fixedly mounted on the rear end of the first processing device. The first processing device includes a flow guiding cavity, a negative pressure extraction device, a drug press, and a connecting pipe. The negative pressure extraction device is fixedly mounted inside the top of the drug press, and the connecting pipe is fixedly connected to the top of the negative pressure extraction device. The flow guiding cavity is fixedly mounted inside the rear end of the drug press. The second processing device includes an extension support, a closed slide plate, a front partition, an alignment sealing plate, a rotating cavity, and a support base. The front partition is fixedly mounted at the front end of the rotating cavity, and the closed slide plate is slidably inserted into the center of the front partition. Through the positioning component, the dryer achieves the purpose of guiding and synchronously guiding the drug powder.
Owner:BEIJING ORIENTAL KINGHERD BIOTECH

Method for small molecule acid assisted liquid phase ultrasonic exfoliation of natural mineral drugs

PendingCN122301574AOrganic solventFluid phase
This invention discloses a method for small molecule acid-assisted liquid-phase ultrasonic exfoliation of natural mineral drugs, comprising: pretreatment of natural mineral drugs: weighing natural mineral drug powder, dispersing it in an organic solvent, performing static soaking treatment, and drying the natural mineral drug solid after soaking for later use; liquid-phase ultrasonic exfoliation: adding pyrite and small molecule acid after pretreatment in step (1) sequentially to a mixed solvent system of water and organic solvent, ensuring the mixture is fully mixed and in contact, and then performing liquid-phase ultrasonic exfoliation treatment, and after treatment, removing the system and allowing it to cool naturally to room temperature; product purification: taking the upper suspension of the mixed system after cooling in step (2), centrifuging to collect the bottom precipitate; washing and collecting the precipitate and drying it to obtain a high-purity exfoliated natural mineral drug product. The method of this invention is green and safe, with simple steps, controllable product morphology, and a maximum yield of 80.36%, applicable to various layered and non-layered natural mineral drugs, improving the consistency of drug efficacy.
Owner:SOUTHEAST UNIV

Weighing device for powder charging machine

The utility model discloses a weighing device for a powder charging machine, which relates to the technical field of weighing devices, is mounted at the bottom end of a conveying mechanism and comprises a workbench arranged at the bottom end of the conveying mechanism, and a weighing body is arranged at the top end of the workbench. A sealing mechanism matched with the conveying mechanism is arranged above the weighing body, and a clamping mechanism is arranged on the outer side of the sealing mechanism. Through cooperative arrangement of the weighing body, the sealing mechanism and the clamping mechanism, powder can be weighed, and meanwhile, the contact amount of powder particles and the weighing body can be reduced, so that the adhesion rate of part of fine particles in the powder on the surface or in gaps of the weighing device is reduced, cross contamination of the powder is reduced, and the quality of the powder is improved. The medicine quality is improved.
Owner:HEBEI XINGAN CIVIL EXPLOSIVE EQUIPMENT CO LTD

Medicine powder injection instrument

The utility model discloses a medicine powder injection instrument, and relates to the technical field of medical instruments. The medicine powder injection instrument comprises an instrument shell, a fan, an oscillation platform, a connector and a catheter, the fan is arranged in the instrument shell; the oscillation platform is arranged on the instrument shell; the connector is fixed on the oscillation platform, the connector is provided with an air inlet, a powder inlet and a powder outlet, the air inlet of the connector is communicated with the air outlet end of the fan, and the powder inlet of the connector is suitable for being connected with a powder container; the near end of the catheter is communicated with the powder outlet of the connector, and the far end of the catheter is suitable for stretching into a target injection position. The utility model provides a medicine powder injection instrument, which realizes intracavity powder injection, effectively prevents medicine powder from being accumulated in an inner cavity of the instrument and a catheter, and is high in medicine powder injection efficiency.
Owner:SHANGHAI YISIMIAO MEDICAL INSTR CO LTD

Medicine dispensing device for hospital pharmacy

The utility model relates to the field of medical auxiliary instruments, in particular to a hospital pharmacy dispensing device which comprises a top plate, a bottom plate arranged below the top plate, a dispensing feeding device fixedly installed above the top plate, a material taking opening formed in one side of the top face of the top plate, a cover plate arranged outside the material taking opening, one end of the cover plate rotationally connected with the top plate, and the other end of the cover plate rotationally connected with the bottom plate. The periphery of the top plate is fixedly connected with a plurality of connecting columns, the bottom ends of the connecting columns are all fixedly connected with the bottom plate, and a medicine dispensing plate is clamped between the top plate and the bottom plate. Residual medicine powder in the crushing cavity can be conveniently cleaned after grinding, and medicine waste is avoided; the arranged medicine collecting bottle is convenient for determining the medicine powder amount for blending, in addition, the medicine temporary storage capacity is achieved, a user can conveniently and freely adjust the medicine proportion and the medicine variety, and then new medicine can be more conveniently prepared.
Owner:颜姝雯

Flux-cored wire rolling forming device

The utility model discloses a flux-cored wire rolling forming device which comprises an operation base, a horizontal roller component, a vertical roller component and a powder filling component, the horizontal roller component comprises a first horizontal roller wheel and a second horizontal roller wheel, a first horizontal roller groove is formed in the outer wall face of the first horizontal roller wheel, and a second horizontal roller groove is formed in the outer wall face of the second horizontal roller wheel. A first horizontal roller groove is formed in the outer wall face of the first horizontal roller, a second horizontal roller groove is formed in the outer wall face of the second horizontal roller, the first horizontal roller groove and the second horizontal roller groove are of a V-shaped structure, and a first cavity is defined by the first horizontal roller groove and the second horizontal roller groove; the vertical roller component comprises a first vertical roller wheel and a second vertical roller wheel, a first vertical roller groove is formed in the outer wall face of the first vertical roller wheel, a second vertical roller groove is formed in the outer wall face of the second vertical roller wheel, and the first vertical roller groove and the second vertical roller groove are each of an arc structure. And the operation process is simplified, and the production requirements of flux-cored wires of different specifications can be met.
Owner:CHANGZHOU MENGLIRUI ELECTRICAL MATERIALS CO LTD

Pill preparation device and method for preparing traditional Chinese medicine preparation

The invention relates to the field of traditional Chinese medicine pill preparation, in particular to a pill preparation device and method for traditional Chinese medicine preparation preparation. The pill making device mainly comprises a stirring part, a pill making part, a screening part and a cleaning part, and automation of the whole process from medicine mud treatment to pill screening is achieved. The stirring part comprises a mixing bin and a double-helix stirring bin and is used for mixing and stirring medicine powder; the shearing part controls the diameter and the length of the medicine strip through a servo reducing mechanism; a pill making part medicine roller and a pill rolling roller are used for dicing and rounding the medicine strips; and the screening part is used for realizing pill grading through a plurality of layers of vibrating detachable screens. The problems that in a traditional pill making process, efficiency is low, specification consistency is poor, cleaning is inconvenient, and pills of multiple specifications cannot be produced synchronously are solved, and the production automation degree and the product quality are remarkably improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM

Dosing and mixing tank

A dosing and mixing tank, comprising a storage mechanism (100), a mixing mechanism (200) arranged on the storage mechanism (100), and a feeding mechanism (300) arranged on the mixing mechanism (200), wherein the storage mechanism (100) comprises a base (101) and a containment tank (102) arranged on the base (101); the mixing mechanism (200) comprises an electric motor (201) arranged on the containment tank (102) and a mixing assembly (202) arranged on the electric motor (201); and the feeding mechanism (300) comprises an air intake assembly (301) arranged at the bottom of the containment tank (102), and a recovery assembly (302) and a material guide assembly (303) which are arranged on the air intake assembly (301). The provision of the storage mechanism (100) facilitates better containment of chemical liquid, and the chemical liquid can be effectively mixed with the use of the mixing mechanism (200). By means of the provision of the feeding mechanism (300), chemical powder can be effectively injected into the chemical liquid together with air, and the chemical powder is added from bottom to top, facilitating the mixing of the chemical powder. Moreover, the provision of the mixing mechanism (200) helps to increase the area of contact between bubbles and the chemical liquid in the storage mechanism (100), improving the mixing effect.
Owner:HUANENG (FUJIAN ZHANG ZHOU) ENERGY CO LTD

Powder filling machine

1. The name of the product of this design: powder filling machine. 2. Purpose of the product of this design: production equipment used for packaging powder in powder-liquid double-chamber bags, belonging to the field of pharmaceutical equipment. 3. The design key point of this appearance design product lies in the shape. 4. The picture or photo that best illustrates the design points: Stereoscopic diagram 1. 5. The bottom surface of this design product is a part that is not easily visible or cannot be seen when in use, so the top view is omitted.
Owner:SHINVA MEDICAL INSTR CO LTD

Gas-driven double-cavity microneedle as well as preparation method and application thereof

The invention relates to a gas-driven double-cavity microneedle as well as a preparation method and application thereof. The preparation method comprises the following steps: S1, preparing a needle tip solution, filling a microneedle mold with the needle tip solution, vacuumizing and drying to obtain a blank cavity microneedle with a first-stage cavity and a second-stage cavity; s2, sequentially filling the I-stage cavity with medicine powder and filling the II-stage cavity with aerogenesis powder through a vacuum method or a centrifugal method, adhering and fixing a medical adhesive tape to the surface of the blank cavity microneedle, and demolding to obtain the gas-driven double-cavity microneedle, the invention also discloses application of the gas-driven double-cavity microneedle prepared by the method in preparation of a drug delivery system, a vaccine delivery system, a medical beauty product, a diagnosis monitoring marker and a gene therapy vector system. The invention has the effects of supporting orthogonal regulation and control of gas production kinetics and drug release behavior, being capable of carrying out customized compatibility aiming at different disease treatment scenes, and having broad-spectrum applicability and clinical transformation potential.
Owner:ZHEJIANG UNIV OF TECH

Nasal dry powder inhalation administration device for children

PendingCN120939377AMedical devicesMedical insufflatorsNasal vestibuleNasal passages
The invention relates to the technical field of nasal preparation administration devices, in particular to a nasal dry powder inhalation administration device for children, which comprises a shell, an extrusion sealing mechanism, an auxiliary administration mechanism and a dose dividing mechanism. Wherein the dose dividing mechanism can realize accurate dose dividing and quantitative control of medicine powder according to physiological characteristics and medication requirements of children of different age groups; the auxiliary drug delivery mechanism is connected to the drug outlet end of the drug delivery pipe, the drug delivery path can be optimized according to the structural characteristics of the nasal cavity of a child, drugs are effectively guided to be deposited in the absorption area of the nasal cavity, and waste of the drugs in non-absorption areas such as the nasal vestibule is reduced; the extrusion sealing mechanism can stably spray out medicine powder in the shell through the medicine feeding pipe, and the medicine powder cooperates with the auxiliary medicine feeding mechanism, so that the delivery efficiency of the medicine in the nasal cavity is improved.
Owner:JIANGSU YUNGOU PHARM TECH CO LTD

Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release

An orally administrable drug powder composition which forms a gastro-retentive RAFT having at least two trigger pulses is provided. The composition contains, at a minimum, (a) at least one drug in an immediate release pulse release form; (b) at least one drug in a delayed trigger release form; (c) at least one non-toxic gas generating agent and (d) a RAFT system, wherein following oral ingestion, the composition provides a self-assembling gastro-retentive RAFT having entrapped therein, the at least one drug of (a) and (b) and the gas generated in situ by the non-toxic gas generating agent, thereby providing a floating gastro-retentive RAFT having a dual pulse system wherein at least the second pulse is a trigger pulse and which retains the at least one drug in the stomach for at least about 3 hours, provided that the composition does not include a gamma hydroxybutyrate and its salts, hydrates, tautomers, or solvates, or complexes thereof.
Owner:TRIS PHARMA INC

Multi-layer co-extrusion film soft bag powder injection for injection

The invention is suitable for the technical field of infusion products, and provides a multi-layer co-extrusion film soft bag powder injection for injection, which comprises a medicine bag, a bag cavity assembly is arranged in the medicine bag, the bag cavity assembly comprises a first bag cavity, a second bag cavity and a weak welding rod, one end of the medicine bag is provided with an infusion port, and the infusion port is communicated with the first bag cavity or the second bag cavity. A hanging hole is formed in one end of the medicine bag away from the infusion opening; a first diaphragm assembly and a second diaphragm assembly are attached to the two sides of the medicine bag correspondingly, and the first diaphragm assembly and the second diaphragm assembly are used for shielding medicine in the first bag cavity and the second bag cavity from light. The peelable first diaphragm assembly is arranged on one side of the medicine bag, and the blocking piece for blocking the hanging hole is arranged at one end of the first diaphragm assembly, so that a user can be forced to inspect medicine powder in the medicine bag before infusion, the effectiveness of medicine is ensured, the safety in the infusion process is improved, and potential safety hazards are avoided.
Owner:NORTHWEST A & F UNIV

Hot air oven for producing freeze-dried bulk drugs

The utility model discloses a hot air oven for freeze-drying bulk drug production, which belongs to the technical field of bulk drug production and comprises an oven, a sealing door is hinged to the surface of the oven, a controller is fixedly connected to one side of the oven, a diffusion mechanism is arranged in the oven, and a heating mechanism is arranged at the top of the diffusion mechanism. A limiting mechanism is arranged on one side of the heating mechanism, a tray is arranged on the top of the limiting mechanism, a vibration motor, a supporting rod, a fixing frame and a screening plate are arranged, the output end of the vibration motor vibrates to drive the supporting rod to vibrate, then the supporting rod vibrates to drive the fixing frame to vibrate, and then the fixing frame vibrates to drive the screening plate to vibrate; and then the screening plate is used for screening the powdery raw material medicine, so that the problems that the traditional raw material medicine cannot be screened after being put into a drying oven, so that part of powdery raw material medicine particles are too large, and follow-up medicine powder mixing is not facilitated are solved, and the practicability is improved.
Owner:LIANYUNGANG GUIKE PHARMA