31 results about "Capsule drugs" patented technology

The invention relates to the technical field of medicine capsule production, and particularly discloses a preparation process for improving the filling quality of a Xinan capsule, which comprises the following six steps: weighing 4-5kg of hawthorn leaf extract powder and 0.5 kg of corn starch, then taking 95% ethanol, preparing a soft material, granulating, drying, crushing, adding auxiliary materials during total mixing, and filling. The auxiliary materials for improving the flowability of the medicine powder are added into the crushed medicine powder, and the auxiliary materials are mixed to cover the surface of the powder to form a hydrophobic layer and directly block water contact, so that the flowability of the medicine powder is realized, the difference between the medicine loading amount and the standard amount can be very small during filling, and the safety of the prepared capsule medicine is ensured.

The invention discloses preparation of an anti-chronic pharyngitis microcapsule medicine and application of the anti-chronic pharyngitis microcapsule medicine in tipping paper for cigarettes, the medicine is MF-GA / IL (at) MPN, and the medicine is composed of an ionic liquid (IL) as an internal carrier and a microcapsule carrier with a metal phenol network (MPN) as a shell; wherein the metal phenol network is formed by aluminum ions and mangiferin through a coordination reaction, and the ionic liquid is CAGE ILs formed by vanillin and choline. The combination of mangiferin and glycyrrhizic acid is used as a strategy for treating chronic pharyngitis, it is found that the effective loaded MF-GA / IL-coated MPN microcapsule preparation is obtained by packaging the two drugs including mangiferin and glycyrrhizic acid with the ionic liquid as the core and the metal phenol network as the shell, the tissue permeability of the drugs is improved, a certain slow release effect is achieved, and the effect of treating chronic pharyngitis is achieved. The bioavailability of mangiferin and glycyrrhizic acid is improved, and the anti-inflammatory activity effect is better achieved.

The utility model discloses an anti-blocking filling machine for capsule medicine preparation and belongs to the technical field of medicine production. A medicine inlet is formed in the upper end of the shell, a stirring mechanism is arranged in the shell and fixedly connected with an anti-blocking mechanism, the anti-blocking mechanism is arranged in a conveying pipe, the conveying pipe is fixedly communicated with the upper end of the shell, a discharging port is formed in the lower end of the conveying pipe, an electronic valve is arranged on the discharging port, and the outer wall of the lower end of the conveying pipe is fixedly connected with a connecting frame. The connecting frame is fixedly connected with the fixing plate, the fixing plate is provided with a filling mechanism, and the filling mechanism corresponds to the discharging port. By means of the unique design and working principle, the capsule medicine preparation device has the remarkable advantages of being efficient in stirring, excellent in anti-blocking performance, accurate in filling, easy and convenient to operate, wide in application and the like, and efficient, reliable and automatic capsule medicine preparation equipment is provided for the pharmaceutical industry.

The utility model relates to capsule medicine powder filling mechanism, its stock bin stirring filling device is installed on stock bin support swing arm, and the transmission connection between filling transmission mandrel and stirring transmission hollow shaft is by linkage part, and hollow support stand column is arranged on the mesa panel of frame, and hollow pivot connection configuration is in hollow support stand column, and power mandrel connection configuration is in hollow pivot, and the upper end of power mandrel is with the upper end transmission connection of filling transmission mandrel, and the lower end of power mandrel is with mandrel drive motor transmission connection, and stock bin support swing arm is connected in hollow pivot, and stock bin support swing arm is located the top of hollow support stand column, and the lower end of hollow pivot is with pivot drive part transmission connection. Hollow support stand column and other structures on the column are supported by the mesa panel of frame, and the load of stock bin support swing arm is relatively reduced, and operation is relatively more stable, and the support structure and power transmission structure help to promote the operation stability and service life of optimization filling mechanism.

The application belongs to the technical field of quality detection of traditional Chinese medicine preparation, and provides a method for establishing volatile / liposoluble component fingerprint spectrum of Xinnaoning capsules. The method comprises establishing volatile component fingerprint spectrum of Xinnaoning capsules and establishing liposoluble component fingerprint spectrum of Xinnaoning capsules, and is to take Xinnaoning capsule drug preparation as a detection object, and to establish a fingerprint spectrum method for the drug preparation by using gas chromatography and mass spectrometry. The method for establishing volatile / liposoluble component fingerprint spectrum of Xinnaoning capsules has the advantages of high stability, high precision and good repeatability. Moreover, the method can evaluate the similarity of liposoluble compounds of Xinnaoning capsules, and provide technical support for realizing more comprehensive and effective control of product quality.

The invention discloses a method for analyzing a pharmacodynamic material basis and metabolites of Longqing capsules. According to the method, an UPLC-Q-Exactive-Orbitrap MS technology is adopted, under the same chromatographic condition and mass spectrum condition, the pharmacodynamic material basis and metabolites of the Longqing capsules are measured and analyzed, 128 compounds are analyzed from the Longqing capsules, 144 exogenous compounds including 61 prototype components and 83 metabolites are analyzed from plasma, urine and excrement of rats in total, and the pharmacodynamic material basis and the metabolites of the Longqing capsules are analyzed to form the Longqing capsules with the pharmacodynamic material basis and the metabolites of the Longqing capsules with the pharmacodynamic material basis and the metabolites of the Longqing capsules with the pharmacodynamic material basis and the metabolites of the Longqing capsules. The main metabolic pathways comprise oxidation, reduction, hydrolysis, methylation, sulfation, glucuronization, composite reactions of various reaction types and the like. The invention provides a scientific basis for quality control and clinical reasonable medication of Longqing capsule medicines.

This utility model relates to the field of pharmaceutical packaging technology, specifically to a capsule pharmaceutical packaging machine. This device, through precise mechanical coordination, ensures that each capsule enters its designated position independently and vertically during the packaging process. Under the continuous action of the vibrating block, the capsules are effectively dispersed and fall one by one into the first through-hole, achieving automatic and neat arrangement. This effectively avoids problems such as capsule tipping or sticking that may occur during manual operation. Subsequently, the capsules accurately fall into the second through-hole of the feeding plate. Each hole is strictly limited to accommodating only a single capsule. The feeding plate is driven by a lead screw to perform precise and controllable step-by-step movement, ensuring that only when the second through-hole moves to the predetermined position will the capsule be released due to the loss of base support. This combination of physical isolation and precise displacement fundamentally guarantees the absolute accuracy and consistency of the packaging quantity each time, greatly reducing packaging errors and achieving a high degree of automation and continuous operation.

1. Name of the designed product: medicine package box (Rhododendron simsi oil capsule). 2. Use of the designed product: the designed product is used for the package of capsule medicine. 3. Design points of the designed product: the combination of shape and pattern. 4. Picture or photo best indicating the design points: perspective view.

The utility model relates to a medicine bottle technical field, concretely is a kind of sealed moisture-proof medicine bottle, including bottle body, the upper end of bottle body is threadedly connected with bottle cap, the bottom inner wall of bottle body is fixedly connected with sealing box, sealing box is filled with drying agent, the inner wall of sealing box is fixedly connected with permeable membrane, the outer circumferential surface of sealing box is fixedly connected with extension ring, extension ring is fixedly connected with bottle body, the inner circumferential surface of extension ring is equipped with several air holes, the inner wall of sealing box is fixedly assembled with baffle, baffle is located above permeable membrane, baffle is polypropylene material quality.The utility model, by setting sealing box, extension ring and air hole etc. component, by extension ring and air hole cooperation, can in the case where sealing box is covered by capsule medicine, make the air in bottle body pass through extension ring and enter sealing box, then be dried by drying agent, to ensure the drying effect of drying agent, improve the moisture-proof performance of medicine bottle.

The utility model relates to the technical field of capsule detection equipment, in particular to soft capsule appearance flaw detection equipment. The utility model provides soft capsule appearance flaw detection equipment which comprises a flaw detector body and a device frame, and a supporting table is fixed to the top of the device frame. By arranging the discharging mechanism, the collecting box, the material blocking frame, the first discharging opening and the second discharging opening, during detection, a medicine plate for packaging a plurality of capsules is placed in a placing area in the discharging mechanism, and two driving motors drive a moving plate to move to the position below the defect detector body to stop; then the air cylinder and the flaw detector body are started to detect flaws of a plurality of capsules, after detection is completed, the driving motor continues to be started to enable the moving plate to move to the first discharging opening and the second discharging opening, and therefore capsule medicine plates fall into the collecting box to achieve the rapid discharging function, manual discharging is avoided, manpower is saved, and the working efficiency is improved. And the detection efficiency is improved.

Capsule pharmaceutical compositions of MRTX1133 (4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-8-fluoro-2-(((2R,7aS)-2-fluorohexahydro-1Hpyrrolizin-7a-yl)methoxy)pyrido[4,3-d]pyrimidin-7-yl)-5-ethynyl-6-fluoronaphthalen-2-ol) in suspension; methods for preparing these compositions, and methods of their use for the treatment of 5 various diseases and disorders.

The utility model provides a high-speed rotary tablet press for isosorbide mononitrate sustained-release capsule medicaments, belongs to the technical field of pharmaceutical production, and aims to solve the problem that a rotary processing part is easy to hurt people when the rotary processing part is operated by the people at present. Comprising a tabletting main body, a tabletting rotating plate, an operation panel, an emergency stop switch, a protective rotating shaft, a shutdown pressing block, a protective plate switching mechanism and a maintenance shutdown mechanism, the tablet pressing part is arranged in the tablet pressing main body; the operation panel is fixedly connected to the right end face of the pressing piece body. The emergency stop switch is fixedly connected to the front side of the operation panel; the protective rotating shaft is rotationally connected to the interior of the pressing sheet main body; the shutdown pressing block is connected to the interior of the pressing sheet main body in a sliding manner; the protective plate switching mechanism is arranged in the tablet pressing main body; and the maintenance shutdown mechanism is arranged on the right side in the tabletting main body. By means of the protection plate opening and closing mechanism, personnel can maintain the tablet pressing part conveniently, and by means of the maintenance stopping mechanism, the safety of the personnel for maintaining the tablet press is guaranteed.

A soft capsule medicament premixing device comprises a barrel and a barrel cover on the upper side of the barrel, a premixing mechanism is arranged on the lower side of the barrel cover and comprises a main rod horizontally and rotatably arranged and a motor capable of driving the main rod to rotate, sliding seats are slidably arranged at the two ends of the main rod in the length direction of the main rod, stirring units are arranged on the lower sides of the sliding seats, and the premixing mechanism further comprises an adjusting unit. The motor is in transmission connection with the two sliding seats, the distance between the two sliding seats can be adjusted, the motor can work to drive the main rod to rotate, stirring and mixing work of the medicament is completed through the stirring units on the lower sides of the two ends of the main rod, the stirring effect is guaranteed, and in the stirring process, even if the medicament flows in the stirring direction due to stirring work, the stirring effect is good. Meanwhile, the two groups of stirring units can move along the direction perpendicular to the stirring axis through the action of the adjusting unit, finally, a stirring effect is generated on the flowing medicament in the barrel body, and the stirring effect is ensured by changing the stirring positions of the stirring units.

The utility model provides a novel dehumidification treatment device for capsule pills, which comprises a base, a shield, a motor, a wind cavity, an impeller, an air inlet pipe, an air outlet pipe, a wind guide tube and a filter ring. External airflow enters the wind cavity through the air inlet pipe and then flows out from the air outlet pipe, forming stable airflow circulation to ensure continuous airflow in the device and quickly discharge humid air to create a low-humidity environment for the capsule pills. The air outlet pipe is provided with air outlet holes around its outer wall to evenly disperse the airflow, ensuring that each part of the capsule pills can fully contact the dry airflow, making the dehumidification more uniform and avoiding local humidity problems. The inner diameter of the air diffuser tube is larger than that of the outer tube, which can diffuse the airflow, slow down the wind speed and make the airflow more evenly distributed around the capsule pills, enhancing the dehumidification effect. The filter ring can effectively filter impurities in the air to prevent dust and other pollutants from contacting the capsule pills, thereby efficiently removing moisture from the capsule pills and improving the quality and stability of the medicine.

The invention relates to the technical field of dry powder inhalers, and discloses a dry powder inhaler capable of adapting to a capsule medicine plate, which comprises a body, a suction nozzle and a movable shell capable of being pressed by moving the two sides of the body, an administration cavity communicated with an administration channel of the suction nozzle is formed in an inner cavity of the body, and an execution cavity communicated with the administration cavity is formed in the lower part of the body; a medicine plate groove penetrating through the execution cavity is formed in the end face of the body, and a limiting strip used for limiting the capsule medicine plate to be located at the puncture position is arranged in the execution cavity. An elastic rod is arranged above the puncture position of the dosing cavity, the end, away from the movable shell, of the push rod abuts against the elastic rod, and the puncture needle at the end of the elastic rod downwards punctures the capsule medicine plate at the puncture position. According to the device, by adapting to the capsule medicine plate, the medicine plate only needs to be pushed to move to the puncture position at a time, and medicine administration can be completed without manually taking out and placing the capsule; and meanwhile, the whole device can adapt to different capsule medicine plates, and the overall applicability and use convenience are greatly improved.

The application discloses a portable medicine detection device and relates to the technical field of medical apparatuses.The application comprises a shell, a medicine inlet pipe is communicated with the top of the shell, and a detection reagent pipe is arranged on the front side of the shell; a fixing assembly is arranged in the shell, the fixing assembly comprises a moving pipe, the moving pipe is slidingly connected to the surface of the medicine inlet pipe, a rubber ring is fixedly connected to the bottom of the medicine inlet pipe, a moving rod is movably connected to one side of the moving pipe, and a protruding block is movably connected to the other end of the moving rod.The setting of the fixing assembly can guide the capsule by using the medicine inlet pipe when the capsule medicine is detected, so that the capsule is vertically downward, manual alignment of the capsule is not needed, after the capsule enters the medicine inlet pipe, the moving pipe is used to move upward to extrude the rubber ring, the rubber ring is deformed inward to extrude the capsule, the function of fixing the top of the capsule is realized, and the convenience during operation is improved.

The application discloses a Chinese medicinal component new drug, safflower and paeony saponin soft capsules, for treating PMDD liver-Qi stagnation syndrome depression subtype. The safflower and paeony saponin soft capsules with stable quality are prepared by optimizing the process, and the mass ratio of safflower saponin and total paeony saponin is 0.05-0.075:0.04-0.06. The pharmacological and pharmacodynamic experiment results prove that the safflower and paeony saponin solution can significantly improve the depression-like emotion of Kunming mice in FST / TST; can significantly improve the depression emotion behavior appearance and pathological index changes of model rats in two PMDD liver-Qi stagnation syndrome depression subtypes, namely natural screening and progesterone withdrawal; and the pharmacological mechanism is to significantly increase the ALLO, P and E2 contents in peripheral serum of the model rats and to increase the ALLO content in the hippocampus brain area. The application further discloses a drug clinical test scheme for treating PMDD liver-Qi stagnation syndrome depression subtype. The application provides a Chinese medicinal component new safflower and paeony saponin soft capsule for treating PMDD liver-Qi stagnation syndrome depression subtype.

The invention discloses a novel application of a Guangkang capsule medicine. According to the application of the Gukang capsule medicine in preparation of the medicine for treating gout, the medicine for treating gout is a medicine preparation prepared from an extract obtained by mixing and decocting 570 g of roots of Japanese banana, 400 g of creeping oxalis, 600 g of fructus psoraleae and 300 g of radix dipsaci with water, 150 g of pseudo-ginseng fine powder, 30 g of fine powder of the roots of Japanese banana and pharmaceutically acceptable auxiliary materials. Animal experiments show that the serum uric acid level of a hyperuricemia model mouse can be remarkably reduced, and joint swelling and inflammatory cell infiltration are relieved. Clinical observation further proves that the traditional Chinese medicine composition has a good curative effect on improvement of arthralgia, limited activity and other symptoms of gout patients, is relatively high in safety and does not have obvious adverse reaction.

The application discloses a cannabinoid 1 type receptor-mediated brain-targeting lipid nanocapsule drug loading system and a preparation and application thereof, and belongs to the technical field of targeted drugs. The brain-targeting lipid nanocapsule drug loading system comprises a drug-loaded lipid nanocapsule, the surface of the lipid nanocapsule is modified with a ligand compound of a CB1 receptor, and the ligand compound is one of quebrachamine, methoxylated myristicin, chelerythrine, ostruthol or cannabigerol. The application utilizes the lipid nanocapsule carrier to load a compound X with neuroprotective activity, prolongs the circulation time of the compound X in the body, adsorbs a ligand compound Y on the surface of the lipid nanocapsule, can specifically recognize the CB1 receptor highly expressed on the brain nerve epidermal cells, can transport across the blood-brain barrier, and improves the drug concentration in the brain tissue and cells. The preparation method provided by the application is simple in operation, easy to popularize, can be used for preparing drugs crossing the blood-brain barrier, and has a wide application prospect.

This utility model discloses a powder filling device for capsule drug production, belonging to the field of capsule powder filling technology. It includes a main body with a rotating seat, on which a first capsule module and a second capsule module are mounted. Through a top-feeding structure, a screw hole is provided on a lifting plate. An adjustable top-feeding assembly mounting rod is mounted on the lifting plate via a connecting screw, allowing for height adjustment according to actual conditions, improving flexibility and adaptability. A limit nut is provided on the connecting screw to lock it in place, ensuring stability after adjustment. A movable cavity is provided at the upper end of the mounting rod, and a connecting block at the lower end of the rubber head is placed in the movable cavity. Working with a spring, this applies an elastic thrust to the capsule during top-feeding, ensuring buffering and allowing the capsule to be ejected normally while preventing deformation from sudden impacts, thus protecting the capsule's integrity.

The invention belongs to the technical field of medicines, and relates to a new application of a wolfberry-phellodendron hypoglycemic capsule medicine, in particular to an application of a wolfberry-phellodendron hypoglycemic capsule in preparation of a medicine for treating or preventing climacteric syndrome. According to the invention, it is found for the first time that the wolfberry-huang hypoglycemic capsule can significantly improve various typical symptoms of the climacteric syndrome and regulate the in-vivo estrogen level; the traditional Chinese medicine composition is free of obvious toxic and side effects after being used for a long time, high in safety and free of drug dependence, and compared with hormone replacement treatment drugs, the risks of inducing tumors, thrombus and the like are avoided, and the patient tolerance is better; the wolfberry-huang hypoglycemic capsule used in the invention is an existing mature preparation, the preparation process is stable, the quality is controllable, a new preparation technology does not need to be developed, industrial conversion is easy to realize, and the clinical popularization value is good.

The utility model relates to the related technical field of detection fixtures, in particular to a detection fixture of a drug effect detection device, which comprises a pressure sensor table, a movable chuck, a chuck fixing sleeve and a fixture assembling component, and the movable chuck is mounted at a driving position on the pressure sensor table. Clamping is needed according to drug effect inspection of different drugs, a user can place a capsule drug on a chuck table after screwing a capsule detection rotating basket and a fastening sleeve to the tail end of a chuck fixing sleeve, and thread disassembly is carried out through a pressure sensor table and a mounting groove in a built-in disc, so that the capsule drug can be detected conveniently and rapidly. According to the capsule drug effect detection device, the chuck table can be installed on the capsule detection rotating basket and the fastening sleeve in a threaded fastening mode, after the chuck table, the capsule detection rotating basket and the fastening sleeve are assembled, the chuck table, the capsule detection rotating basket and the fastening sleeve are installed on the capsule drug effect detection device, and the detection clamp can not only clamp tablets but also clamp capsule drugs. And the two different detection clamps are assembled together.

The present application relates to the technical field of medicine capsule detection, and particularly to a capsule medicine solubility detection device, which comprises an obstacle module, a liquid extraction module, a vibrator, a constant temperature controller, a temperature sensor, a visual sensor and a central control assembly. The present application analyzes each acid real-time image, and according to the analysis result, makes a first determination on the target capsule medicine to determine whether to start a disturbance mode, makes a second determination on the target capsule medicine based on the disturbance mode to obtain a second determination result, determines whether to make a second type detection on the target capsule medicine according to the second determination result, receives each alkaline real-time image monitored by the visual sensor in real time during the second type detection, analyzes each alkaline real-time image to make a third determination on the target capsule medicine, and based on the third determination result, the central control assembly outputs a final detection report of the target capsule medicine in combination with the first determination result and the second determination result.

The utility model aims to provide a pharmacy machine swing mechanism, including chassis and rotating subassembly, on the chassis is provided with circular curved groove, on the chassis is provided with convex rail, rotating subassembly includes the rotary disk, upper support, slide bar, lower support, slider and drive piece, drive piece is provided the bottom of chassis, the rotary disk is provided on the output end of drive piece, slide bar, lower support, slider and drive piece. The rotary disc is located above the base plate, the sliding rod is arranged on the rotary disc in a penetrating mode in the axial direction of the rotary disc, one end of the sliding rod abuts against the protruding rail, the upper support is arranged at the other end of the sliding rod, the sliding block is arranged on the rotary disc in a penetrating mode in the radial direction of the rotary disc, and one end of the sliding block is arranged in the circular curved groove in a sliding mode. When the driving piece drives the rotary disc to rotate, the sliding rods slide along the protruding rails, the sliding blocks slide along the circular curved grooves, and then the upper support and the lower support are buckled or separated. Therefore, inaccurate dosage of the capsule caused by overflowing or throwing out of the medicine from the capsule is avoided.

The utility model relates to the technical field of capsule packaging equipment, in particular to a capsule medicine plate boxing machine which comprises an installation frame and a machining table fixed to the top end of the installation frame, inner plates are fixed to the two sides of the top end of the machining table, transmission teeth are fixedly arranged on the inner plates on the two sides in a sleeved mode, and the inner sides of the transmission teeth are fixedly connected with belt wheels through rotating shafts. A belt sleeves the outer side of the belt wheel, a box body is placed at the top end of the belt, outer plates are arranged on the outer sides of the inner plates on the two sides, a positioning hole is formed in the middle of each group of outer plates, a threaded rod is arranged in the middle of the positioning hole in the outer plate on one side, sleeves sleeve the two sides of the threaded rod, and the outer sides of the outer plates are fixedly connected with clamping plates through adjusting assemblies; the adjusting assembly comprises two sets of connecting plates and two sets of pin shafts, the two sets of connecting plates are fixedly connected through the pin shafts, and the inner side walls of the outer plates are fixed to sleeves, so that when the threaded rods rotate, the sleeves can drive the outer plates on the two sides to move, the width adjusting function is achieved, and the capsule box width adjusting device is suitable for capsule boxes with different widths.

The invention provides a preparation method of a Yulan hypoglycemic capsule pharmaceutical composition. The preparation method comprises the following steps: crushing radix scutellariae, folium mori and other traditional Chinese medicinal materials into coarse powder, adding a betaine-malic acid aqueous solution, and carrying out ultrasonic extraction and filtration to obtain an extract A and medicine residues A; carrying out heating reflux extraction on the medicine residue A by using an ethanol solution, and sieving to obtain an extract B; combining the extract A and the extract B, adding ethanol, refrigerating, and finally concentrating into thick paste; various pharmaceutical auxiliary materials can be added into the obtained thick paste to prepare corresponding pharmaceutical preparations. The process can solve the problems of low baicalin content, more water-soluble impurities and the like in the traditional process, the product quality is stable, the indexes meet regulations, and the process is suitable for actual production.

The invention belongs to the technical field of aquaculture, and relates to a method for preparing fairy shrimp capsules from fresh fairy shrimps and application of the fairy shrimp capsules. The method for preparing the fairy shrimp capsule from fresh fairy shrimps comprises the following steps: reconstructing a living body compensation mechanism; gene segment remodeling is achieved through intergenerational reproduction; capsule drug performance curing; and deeply refining and purifying the capsule. In the application of the fairy shrimp capsules in improving the survival rate of the penaeus vannamei, the fairy shrimp capsules are used as feed to feed the penaeus vannamei. In the application of the fairy shrimp capsule in improving the culture wastewater body, the fairy shrimp capsule is used as a feed to culture penaeus vannamei, and the pH value and the ammonia nitrogen content in the produced culture wastewater are superior to those in culture wastewater produced by culture with other feeds. According to the method, the cavity characteristics of fairy shrimps are utilized, the biological capsules with the functions of preventing diseases and insect pests, strengthening nutrition and the like are developed, high-quality feed is provided for fish and shrimp culture, the utilization efficiency of marine resources is improved, and water pollution caused by feeding of a large number of drugs for treating diseases and insect pests is avoided.

The utility model provides a ferrous fumarate docusate sodium capsule preparation mixing device, and belongs to the technical field of capsule medicament production. The device is ingenious in structure, good in material mixing effect, good in splash-proof effect and convenient in material loading and taking. A mixing barrel of the device is erected in a base, a driving motor is arranged on the base, a driving gear is arranged at the driving end of the driving motor, the driving gear is meshed with a gear ring arranged outside the mixing barrel, a stirring disc is hoisted on the base and inserted into the mixing barrel, materials are added into the mixing barrel, and the stirring disc stands and rotates in the mixing barrel to form relative movement. And stirring and mixing the materials. The mixing barrel of the device is detachably erected and is convenient to mount, dismount, replace and clean, the discharging hopper is arranged on the stirring disc, material adding and progress observation are convenient, material splashing can be avoided, the contact area between the spiral stirring pieces and materials is increased, the stirring efficiency is high, and the stirring effect is good.

1. Name of the product in this design: Packaging Box (Glucosamine Sulfate Capsules). 2. Purpose of this design: For packaging glucosamine sulfate capsules. 3. The key design elements of this product are the combination of shape, pattern, and color. 4. The image or photograph that best illustrates the design's key points: a 3D model. 5. The design for which protection is sought includes color.

A manual capsule filling device includes a horizontally arranged capsule body plate for holding capsules, a baffle plate that is detachably connected to the capsule body plate, and a capsule cap plate for holding capsule caps, the capsule cap plate being detachably connected to the baffle plate; it also includes a filling plate for filling with medicinal powder, an intermediate plate for fixing the capsule caps, and a pressing plate for compacting the medicinal powder inside the capsules, the capsule body plate and the filling plate being detachably connected, and the intermediate plate and the capsule cap plate being detachably connected. This manual capsule filling device reduces waste during the initial simulated production process in capsule drug development, saves costs, and is convenient and quick to operate.