The invention relates to a vamp cleaning device for shoe processing, and in particular relates to an efficient vamp cleaning device for shoe processing. The invention aims at providing an efficient vamp cleaning device for shoe processing, which is time-saving and labor-saving, can perform comprehensive cleaning on the vamps, and can guarantee the appearance and quality of the vamps. To solve the technical problems, the following technical scheme is adopted: the efficient vamp cleaning device for shoe processing comprises a support plate, a fixing block, a top plate, a vertical rod, a hairbrush, a lifting device and the like, wherein the lifting device is arranged in the middle of the right side surface of the support plate, the fixing block is connected to a lifting part of the lifting device, a placing groove is formed in the middle of the top of the fixing block, and the top plate is mounted on the top of the support plate through a bolt connection method. For the efficient vamp cleaning device, the mixed water and cleaning fluid are sprayed to the vamps, so that the vamps can be well cleaned by the hairbrush, the cleaning effect is good, and clamping blocks can fix the shoes, so that the problem that during the cleaning process of the vamps, the shoes are movable is solved.