62 results about "Platycladus" patented technology

The invention relates to the technical field of scalp care, in particular to a hair-blacking composition for promoting melanin secretion and a preparation method of the hair-blacking composition. Comprising the following components in parts by weight: water, ethanol, a ginseng root extract, a polygonum multiflorum extract, a cacumen biotae extract, a licorice root extract, an eclipta prostrata extract, a ganoderma atrum extract, a rhizoma bletillae root extract, a mulberry leaf extract, radix sophorae flavescentis powder, a glossy privet fruit extract, a raspberry fruit extract and a black sesame extract. According to the technical scheme, the ganoderma atrum extract is prepared through enzymolysis-ultrasonic combined modification, a cell wall structure is decomposed through compound enzyme, then cell remains are further broken through the ultrasonic cavitation effect, and the release rate of active peptide and polysaccharide is increased; the hair-blacking composition can promote the generation of hair melanin so as to blacken hair, improve the hair quality, enable the hair to become tough and elastic, and enable the hair to gradually become black, smooth and firm after being smeared on the scalp for a long time.

The invention discloses a composition for growing and nourishing hair as well as a preparation method and application thereof. The composition is prepared from various components including 20 to 30 parts of cacumen biotae extract, 2 to 7 parts of eclipta prostrata extract, 3 to 9 parts of specnuezhenide and the like. The preparation method comprises the steps of raw material pretreatment, active ingredient extraction, compound blending, microcapsule embedding and preparation forming, the cacumen biotae is subjected to a supercritical extraction process, and the eclipta prostrata is subjected to an ultrasonic-assisted enzymolysis-subcritical water extraction combined process. Experiments show that the composition can significantly increase the hair growth rate, maintain the hair follicle growth period, increase the diameter of a hair bulb part, effectively improve hair follicle health through the synergistic effects of activating hair follicle stem cells, inhibiting apoptosis and the like, and can be applied to preparation of hair care products for promoting hair growth.

This application relates to the field of shampoo bar technology, and more particularly to a traditional Chinese medicine shampoo bar and its preparation method. The traditional Chinese medicine shampoo bar includes active components of traditional Chinese medicine and basic raw materials for forming the soap body; the active components of traditional Chinese medicine are formed by soaking, decocting, and filtering the following raw materials in the indicated weight ratios: Platycladus orientalis leaves, dried ginger, chrysanthemum, Sapindus mukorossi, Gleditsia sinensis, duckweed, Eclipta prostrata, Ligustrum lucidum, processed Polygonum multiflorum, Sophora flavescens, Kuding tea, peppermint, Artemisia argyi, ginseng, Ganoderma lucidum, Angelica sinensis, mulberry leaves, and Perilla frutescens; wherein, the decoction solvent for the raw materials is rice water. The traditional Chinese medicine shampoo bar formula provided in this application is entirely made from traditional Chinese herbs, has high safety, and has the advantages of effectively cleaning the scalp, preventing hair loss, promoting hair growth, and darkening and brightening hair, effectively solving problems such as oily scalp, itchy scalp, acne on the scalp, increased dandruff, hair loss, and gray hair. The preparation process can maximize the extraction of the effective components of traditional Chinese medicine and can be mass-produced.

This invention discloses a targeted antibacterial and repairing scalp shampoo containing a four-herb compound and its segmented preparation process, belonging to the technical field of functional herbal hair care products. Based on the traditional Chinese medicine theory of principal, assistant, and adjuvant herbs, this invention uses a precise compound of four herbs—Platycladus orientalis leaf, Clematis chinensis, Dictamnus dasycarpus bark, and Paeonia suffruticosa—combined with an amino acid cleansing system and multiple antibacterial and repairing components to create a synergistic formula. It employs a unique segmented salt-addition and low-temperature step-by-step feeding process, locking in the activity of the herbs at 35℃~40℃. Stability is regulated through two salt additions, and properties are optimized through constant-temperature maturation, solving the problems of traditional products such as activity loss, poor stability, single efficacy, and disordered formulation. This product can target and inhibit Malassezia, eradicate stubborn dandruff, reduce inflammation and itching, balance oil and water, repair the scalp barrier, and nourish hair roots. Its pH is suitable for the slightly acidic environment of the scalp, making it gentle and non-irritating, suitable for long-term treatment of sensitive, seborrheic, and permed / dyed scalps. The formula and process are novel, creative, and practical, and can be industrially mass-produced.

This invention provides a traditional Chinese medicine composition and its application in the preparation of a topical herbal eye patch for treating thyroid eye diseases, belonging to the field of biomedical technology. The herbal composition consists of *Gynostemma pentaphyllum*, peppermint, *Platycladus orientalis* leaves, borneol, cicada slough, *Astragalus membranaceus*, *Selaginella tamariscina*, *Pteris vittata*, *Scutellaria baicalensis*, apricot leaf, and *Ipomoea aquatica*. Using this herbal composition as raw material, a topical herbal eye patch is prepared. This patch acts directly on acupoints and skin around the eyes, allowing the medicinal properties to penetrate the skin and reach the eye system, achieving the effects of promoting blood circulation, clearing heat and detoxifying, invigorating qi and unblocking meridians, reducing swelling and improving vision. It is suitable for the treatment of thyroid-related eye diseases. This invention's topical herbal eye patch can effectively improve clinical symptoms such as exophthalmos and eye inflammation in patients with thyroid eye diseases, positively impacting their quality of life and effectively improving the clinical treatment efficacy of this disease. The topical herbal eye patch provided by this invention can be further promoted and applied in the clinical treatment of thyroid eye diseases.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine preparation for treating alopecia and a preparation method thereof. The invention discloses a traditional Chinese medicine preparation for treating alopecia. The traditional Chinese medicine preparation is prepared from the following components in parts by mass: 1-10 parts of angelica sinensis, 10-40 parts of radix rehmanniae recen, 1-10 parts of radix rubiae, 1-10 parts of cacumen biotae, 1-10 parts of roselle, 1-10 parts of poria cocos, 1-6 parts of cassia twig and 1-10 parts of honey-fried licorice root. According to the traditional Chinese medicine preparation for treating alopecia, on the basis of nourishing the liver and the kidney, a product for tonifying spleen and promoting diuresis and medicines for helping digestion, strengthening the heart and dredging collaterals are added, so that the efficacy of the medicines can quickly reach the whole body, the liver and the kidney are nourished, marrow sea is filled, the result is doubled with half the effort, and the curative effect is exact. The traditional Chinese medicine preparation for treating alopecia is a pure traditional Chinese medicine preparation and has no toxic or side effect.

This invention belongs to the technical field of daily-use shampoo and hair care raw materials, specifically relating to a composition with hair-darkening effects and its application. The composition with hair-darkening effects provided by this invention is formulated from a compound of Platycladus orientalis leaf extract, Polygonum multiflorum extract, Eclipta prostrata leaf extract, Gynostemma pentaphyllum extract, palmitoyl tetrapeptide-10, L-arginine, and decapeptide-4. By adjusting the types and amounts of each component, the interaction between the components is improved, thereby increasing the relative activity of tyrosinase and the relative content of melanin, indicating that the components have a synergistic effect and excellent hair-darkening efficacy. The hair-darkening composition obtained by this invention is applied to the preparation of shampoo, which exhibits excellent hair-darkening effects and high safety, and has broad market application value in the field of hair-darkening or hair-protecting products.

This invention discloses an anti-hair loss hair root mask, its preparation method, and its application, relating to the field of cosmetic technology. The anti-hair loss hair root mask comprises the following components by weight percentage: 4.0%~9.0% anti-hair loss composition; the anti-hair loss composition comprises the following raw materials: plant extracts, enzyme activators, and a reconstitution system; the enzyme activator is selected from at least one of the following: β-glucosidase derived from Aspergillus niger, β-glucosidase derived from almonds, cellulase complex enzyme, malt extract, and citrus fruit fermentation broth; the plant extract includes Platycladus orientalis leaf extract. The anti-hair loss hair root mask, its preparation method, and its application of this invention achieve a significant increase in raw material utilization and anti-hair loss efficacy through targeted enzymatic release of active ingredients; the innovative product form ensures stable enzyme activity and precise efficacy; it also has scalp oil control and soothing effects and is easily mass-produced industrially.

This invention discloses an anti-hair loss composition, its preparation method, and its application, relating to the field of cosmetic technology. The anti-hair loss composition comprises the following raw materials: plant extracts, enzyme activators, and a reconstitution system; the enzyme activator is selected from at least one of the following: β-glucosidase from Aspergillus niger, β-glucosidase from almonds, cellulase complex enzyme, malt extract, and citrus fruit fermentation broth; the plant extract includes Platycladus orientalis leaf extract; the reconstitution system includes a moisturizing stabilizer, a chelating agent, a buffer system, and deionized water. The anti-hair loss composition, its preparation method, and its application of this invention, through targeted enzymatic hydrolysis technology, efficiently convert inactive glycoside precursors in Platycladus orientalis leaf extract into free flavonoids with targeted anti-hair loss activity, significantly improving raw material utilization and active ingredient yield, achieving a technological breakthrough from "passively adding raw materials" to "actively generating active substances."

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating chronic refractory cough and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following fifteen traditional Chinese medicines in specific parts by weight: blackberry lily, roasted ephedra, asarum, bamboo juice pinellia ternate, raw liquorice, radix bupleuri, fried scutellaria baicalensis, fructus aurantii, platycodon grandiflorum, roasted perillaseed, almond, wild buckwheat, Japanese metaplexis pericarp, calyx seu fructus physalis and pericarpium trichosanthis. Aiming at the core pathogenesis of the chronic refractory cough, such as residual evil and turbidity and lung-qi obstruction, evil and turbidity are separately eliminated by a method of separately eliminating and discharging, and the lung-qi is diffused and restored. The traditional Chinese medicine composition is reasonable in component and remarkable in curative effect, clinical data shows that the traditional Chinese medicine composition can effectively improve core symptoms such as cough, expectoration and throat itching, no obvious adverse reaction is found, and safety is high.

The present application relates to the field of daily chemical industry and traditional Chinese medicine washing and protecting technology, in particular to a traditional Chinese medicine shampoo for relieving itching, removing dandruff and preventing hair loss and a preparation method thereof, which is prepared from 12 kinds of traditional Chinese medicines, including Platycladus orientalis, Radix Angelicae Sinensis, Radix Polygoni Multiflori, Herba Viscum, Ganoderma lucidum, etc., and auxiliary materials including gelatin, menthol, vitamin E, tea oil, a compound foaming agent compounded from amino acid and coconut oil. The preparation method is to extract effective components of traditional Chinese medicines by three times of high-temperature and high-pressure decoction, filter and concentrate under normal pressure, and then add auxiliary materials in sequence according to ladder type temperature to mix and prepare. The present application has the triple effects of relieving itching, removing dandruff, nourishing blood and hair, and nourishing scalp, is mild and non-irritating, and can reduce dandruff after 3 days of continuous use, has good product stability, and is suitable for long-term use of various hair types.

The application discloses a kind of American ginseng compound antioxidant products, is prepared from the following mass fraction components extraction: American ginseng 20-30 parts, 15-25 parts of radix rehmanniae preparata, 20-28 parts of dogwood, 15-25 parts of radix scrophulariae, 15-25 parts of gardenia, 8-12 parts of safflower, 18-22 parts of chuanxiong, 20-26 parts of citrus aurantium, 18-25 parts of alocasia, 10-20 parts of polygala, 16-26 parts of Platycladus branchlet, 15-25 parts of hovenia dulcis thunb, after screening, cleaning, crushing, weighing, alcohol extraction, water extraction, concentration and the like step is made.Compared with prior art, the application obtains the beneficial effect: synergistic effect between components, by tonifying qi and invigorating the spleen, nourishing liver and kidney, clearing heart and detoxifying, promoting blood circulation and qi movement, it has the effect of root and original for senile dementia, using reasonable extraction method is beneficial to the extraction of each effective component;Since the components of the application are non-toxic commonly used medicinal materials, there is no harm to the body after use, and there is no side effect.

The application discloses a traditional Chinese medicine composition for treating insomnia, anxiety depression and AD, a preparation method and application thereof. The traditional Chinese medicine composition adopts an ethanol extract of raw medicinal materials, and the raw medicinal materials include, by weight, 175-185 parts of polygala root, 160-170 parts of jujube seed, 90-100 parts of platycladus seed, 150-160 parts of jujube, 160-170 parts of fried licorice, 160-170 parts of astragalus, 150-160 parts of angelica, 150-160 parts of salvia miltiorrhiza, and 155-165 parts of schisandra chinensis. The raw medicinal materials in the traditional Chinese medicine composition are based on the polygala root, and are combined with the jujube seed, the platycladus seed, the jujube, the fried licorice, the astragalus, the angelica, the salvia miltiorrhiza and the schisandra chinensis. The components have a synergistic effect, can treat insomnia, anxiety depression and AD, and have the advantages of small side effect of traditional Chinese medicine and difficulty in drug resistance.

The invention discloses an organic acid-containing anti-hair-loss composition based on a cacumen biotae extract, which comprises the cacumen biotae extract and an organic acid as anti-hair-loss active components, and the acid is succinic acid or malic acid or a combination of the succinic acid and the malic acid. The invention also provides application of the anti-hair loss composition in regulating hair follicle energy metabolism and preventing hair loss. The composition containing the cacumen biotae extract, the succinic acid and the malic acid can promote the activity of hair papilla cells, enhance the energy metabolism of the cells, recover the function of hair follicles damaged by oxidation and recover the energy metabolism of the hair follicles damaged by oxidation, so that the composition has a good effect of preventing and treating alopecia, stimulates hair growth and has few toxic and side effects.

The application belongs to the technical field of seedling quality grading, and discloses a quality grading method for Platycladus orientalis seedlings in situ based on electrical impedance spectroscopy, which comprises the following steps: a Platycladus orientalis seedling in-situ measurement device is built for non-destructive measurement of root EIS in situ; an EIS-100 system is used to measure EIS parameters; based on a GSFS-FCM algorithm, input data are clustered, and the optimal cluster number K and the optimal cluster center coordinate matrix are output; according to the optimal cluster number K and the optimal cluster center coordinate matrix, the final membership degree is calculated and the classification is divided through the FCM algorithm, the quality grade to which the Platycladus orientalis seedling belongs is output, and the whole process from electrical impedance measurement to quality grading is completed. The above-mentioned grading method is adopted, the GSFS-FCM algorithm can automatically determine the classification number, automatically find the cluster center, reduce the iteration number of the algorithm, has high accuracy, and breaks away from the traditional grading method which relies on morphological parameters of the aboveground part.

The application discloses a processing device for peeling platycladus orientalis, and relates to the technical field of vegetable and fruit peeling.The processing device for peeling platycladus orientalis comprises a machine body and an electrical cabinet, the electrical cabinet is fixedly connected to the front face of the machine body, the top of the machine body is fixedly connected with a feeding inclined plate, characterized in that: a flushing mechanism is fixedly connected inside the machine body, a feeding transmission mechanism is rotatably connected inside the machine body, a radial adaptation mechanism is fixedly connected inside the feeding transmission mechanism, a series processing wheel set is fixedly connected inside the feeding transmission mechanism, and an electric heater is fixedly connected inside the machine body.The processing device for peeling platycladus orientalis is provided with the feeding transmission mechanism, the radial adaptation mechanism, the series processing wheel set and the flushing mechanism, so that the posture of the platycladus orientalis after falling is automatically adjusted, the peeling efficiency of the device for platycladus orientalis is improved, the device is prevented from being blocked due to the entanglement and extrusion of the platycladus orientalis, and the energy consumption of the device is reduced.

This invention provides an extract of Platycladus orientalis leaves, its preparation method, and its application. Specifically, the Platycladus orientalis leaf extract composition uses Platycladus orientalis leaves as raw material. First, extract 1 is obtained by supercritical fluid extraction. Then, the residue is collected and refluxed to obtain extract 2. Extracts 1 and 2 are combined in a specific ratio to obtain the Platycladus orientalis leaf extract composition. The composition has a synergistic effect and a significant anti-hair loss effect.

This invention belongs to the field of plant tissue culture technology, specifically relating to a rapid propagation method for *Platycladus orientalis* (North American cypress) tissue culture. The method includes the following steps: variable-temperature electrostatic treatment of *Platycladus orientalis* branches; preparation of seedling-strengthening composite particles; induction culture and propagation of explants treated with variable-temperature electrostatic treatment; rooting culture and hardening-off transplanting of the rejuvenated seedlings. This invention, through screening the sterilization method, induction medium, propagation medium, seedling-strengthening medium, and rooting medium formulations, uses current-year *Platycladus orientalis* branches as explants. After sterilization, the explants are sequentially placed in induction medium, propagation medium, seedling-strengthening medium, and rooting medium for culture, and the optimal culture conditions are controlled to achieve an explant bud induction rate of over 92%, a propagation coefficient of over 5.0, a rooting rate of over 85%, and a transplant survival rate of over 87%. This provides a foundation for large-scale propagation and variety improvement of *Platycladus orientalis* seedlings and is of significant value for the full development of *Platycladus orientalis* resources.

The application discloses a traditional Chinese medicine composition and a preparation method and application thereof; active ingredients of the traditional Chinese medicine composition include rose, bergamot, cydonia, poria cocos, Chinese yam, gordon euryale seed, coix seed, sea buckthorn, malt, chicken gizzard, angelica, longan, medlar, donkey-hide gelatin, mulberry, kelp, oyster, dandelion, dried tangerine or orange peel, platycladus, yellow mustard seed, peach kernel, saffron, radix astragali, American ginseng, raw sun-dried ginseng, dendrobium officinale, lily, ganoderma lucidum, jujube and mint; the traditional Chinese medicine composition is formed by the principle of monarch, minister, assistant and guide, forms a traditional Chinese medicine prescription of specific active ingredients, forms a herbal ointment that treats in all directions, has a remarkable curative effect on breast nodules, and has a good taste, is portable, and meets the long-term treatment requirements.

The present disclosure relates to the technical field of cosmetics, and in particular to a Platycladus orientalis extract, a preparation method therefor and use thereof. Also provided is a Platycladus orientalis extract, comprising the following components in parts by mass: 0.121-0.902 parts of isoquercetin, 1.113-2.420 parts of afzelin, 2.825-4.481 parts of amentoflavone, 0.090-2.234 parts of pinusolide, and 510.61-759.44 parts of D-(-)-Quinic acid. The present disclosure provides a Platycladus orientalis extract comprising a certain amount of isoquercetin, afzelin, amentoflavone, pinusolide and D-(-)-Quinic acid, which has the efficacy of preventing and treating alopecia and can be used as an alopecia-preventing raw material in alopecia-preventing products.

This invention discloses a traditional Chinese medicine shampoo for androgenetic alopecia caused by liver and kidney deficiency, its preparation method, and its application. Belonging to the field of traditional Chinese medicine technology, the shampoo uses processed Polygonum multiflorum, wine-processed Ligustrum lucidum, Eclipta prostrata, ginseng, Angelica sinensis, safflower, Salvia miltiorrhiza, Platycladus orientalis leaves, mulberry leaves, honey-processed mulberry bark, Sophora flavescens, Cnidium monnieri, Paeonia suffruticosa, Cercis chinensis bark, ginger, Sapindus mukorossi, Gleditsia sinensis, and Clematis chinensis as raw materials, prepared through water extraction and concentration. This invention achieves both symptomatic and root-cause treatment, addressing both the underlying cause and symptoms. It intervenes in androgenetic alopecia through the HIF-1 / VEGE and IL-17 pathways, promoting angiogenesis and improving microcirculation in the scalp, inhibiting follicular immune inflammation, and creating a favorable environment for hair follicle growth. Compared with existing technologies, this invention has irreplaceable advantages in improving local symptoms such as oily scalp, itching, and dandruff.

This invention belongs to the field of cosmetic technology and discloses a soothing and anti-hair loss hair growth liquid and its preparation method. The hair growth liquid is composed of a compound anti-hair loss active ingredient, a scalp soothing and repairing agent, a penetration enhancer, an alcohol solvent, a surfactant, a pH adjuster, a preservative, and water. The compound anti-hair loss active ingredient is obtained by gradient ethanol extraction and concentration of five raw materials, including Platycladus orientalis leaves and Drynaria fortunei, in a specific ratio. The scalp soothing and repairing agent is obtained by decoction and concentration of raw materials such as Salvia miltiorrhiza and Aralia elata root. During preparation, the final product is obtained through stepwise extraction, density control, specific sequential compounding, and low-temperature maturation processes. This invention, through the synergy of raw materials and processes, enables the product to have good effects in preventing hair loss, promoting hair growth, and soothing the scalp, and also exhibits good stability.

The invention discloses a composite composition with a scalp care effect and application thereof, the composition is composed of a cacumen biotae extract, a yucca extract, a towel gourd extract and a sargassum fusiforme extract, and the preparation process of the composite composition ensures excellent stability and permeability through composite enzymatic hydrolysis, ultrasonic extraction and high-pressure homogenization treatment. The composition provided by the invention effectively solves the problems that active ingredients are difficult to permeate, hair follicle growth is promoted and the like, and is suitable for developing hair products such as shampoo, hair conditioners, hair nourishing liquid, scalp essence and the like.

The application discloses a plant lactobacillus plantarum CCFM1351 prepared metaplasma based on multi-target for preventing hair loss and protecting hair, and belongs to the technical field of microorganisms and the technical field of medicine. The plant lactobacillus plantarum CCFM1351 prepared metaplasma has the functions of regulating hair follicle development and inhibiting apoptosis, can inhibit the expression of BAX, TGF-beta 2 and DKK-1 of hair follicle dermal papilla cells (HDPC), and promote the expression of VEGF in HDPC. Compared with the same concentration of Platycladus orientalis, the Platycladus orientalis fermentation supernatant prepared by the plant lactobacillus plantarum CCFM1351 can promote the expression of Cyclin D1 mRNA and IGF-1 mRNA of HDPC. The plant lactobacillus plantarum CCFM1351 prepared metaplasma can be used for preparing products for preventing and / or treating hair loss, and has great application prospect.

This invention discloses a method and application for extracting active ingredients from Platycladus orientalis leaves based on enzymatic reactions, relating to the field of cosmetic technology. The method includes the following steps: S1. Providing Platycladus orientalis leaf extract; S2. Providing an enzyme activator, wherein the enzyme activator is selected from at least one of the following: β-glucosidase from Aspergillus niger, β-glucosidase from almonds, cellulase complex enzyme, malt extract, and citrus fruit fermentation broth; S3. Mixing the enzyme activator with the Platycladus orientalis leaf extract to carry out an enzymatic reaction, thereby obtaining Platycladus orientalis leaf active ingredients based on the enzymatic reaction. The method and application of this invention for extracting Platycladus orientalis leaf active ingredients based on enzymatic reactions utilize diversified enzyme activator sources, balancing efficient conversion and compliant application. By optimizing the enzyme powder reconstitution system, stable storage of enzyme activity is ensured, and targeted and efficient conversion is achieved through precise enzymatic hydrolysis processes.

This invention discloses a herbal hair comb for promoting hair growth, thickening, and fragrance, and its preparation method, belonging to the technical field of herbal hair care products. This invention uses Polygonum multiflorum, Platycladus orientalis leaves, Eclipta prostrata, and mulberry leaves as principal herbs to nourish the liver and kidneys, replenish essence and blood, cool the blood and stop bleeding, and promote hair growth and darken hair, directly targeting the main symptoms of hair loss and gray hair. Red ginseng, Angelica sinensis, Paeonia suffruticosa, and Poria cocos are used as assistant herbs to replenish qi and blood, promote blood circulation and remove blood stasis, strengthen the spleen and eliminate dampness, assisting the principal herbs in improving scalp microcirculation. Eupatorium fortunei, cloves, sandalwood, styrax, rose, Angelica dahurica, Kaempferia galanga, Asarum heterotropoides, Magnolia biondii, Nardostachys jatamansi, ginger, and rhubarb are used as adjuvant herbs to open the orifices with aromatics, unblock the meridians and relieve pain, dispel wind and cold, clear heat and detoxify, while simultaneously using aroma to soothe nerves and improve the scalp environment. Licorice and plant adhesive powder are used as guiding herbs; licorice harmonizes the other herbs, and plant adhesive powder not only acts as a binder but also, due to its warm and pungent nature, guides the medicine upwards to the head meridians and fixes the slow release of the medicinal effects.

The invention discloses a hair growth composition for enhancing hair follicle microcirculation by using cacumen biotae volatile oil and a kaoliang spirit alcohol extract and a preparation method thereof, and belongs to the technical field of hair growth and care products, the hair growth composition comprises the following components in percentage by mass: a hair follicle microcirculation activation component: 0.01-0.05 wt% of cacumen biotae volatile oil and 0.1-5.0 wt% of kaoliang spirit alcohol extract; an extracellular matrix strengthening and intercellular communication promoting component: 0.001 to 0.05 wt% of acetyl tetrapeptide-3; 0.1 to 2.0 wt% of an angelica polysaccharide extract; 0.1 to 1.0 wt% of sodium hyaluronate; and 0.05-2.0 wt% of carbenoxolone acid, which is used for up-regulating the expression of Connexin43 (Cx43) protein in hair follicle outer root sheath cells. The composition aims at solving the technical problems that an existing hair growth product only improves hair follicle microcirculation but cannot effectively wake up the activity of hair follicle stem cells, and continuous hair growth is difficult to achieve.

This invention relates to the technical field of wound care spray formulations, providing a wound repair spray based on herbal extracts and its preparation method. The invention first uses an alkaline alcohol / aqueous solution of *Broomia spp.* leaf extract, neohesperidin, and scopolamine hydrobromide as the extraction system, employing heated ultrasonic extraction. After extraction, dilute HBr is added dropwise to adjust to a weakly acidic state, yielding an extract of *Broomia spp.* leaf extract, neohesperidin extract, and scopolamine hydrobromide extract. This extract is then compounded with extracts of *Bletilla striata*, *Ampelopsis japonica*, *Sanguisorba officinalis*, *Phellodendron chinense*, *Scutellaria baicalensis*, *Polygonum cuspidatum*, and *Platycladus orientalis* leaf extracts to obtain the wound repair spray. During the extraction process, the extract system is stable, homogeneous, clear, and transparent, without precipitation or stratification. The resulting wound repair spray is gentle on the skin and has minimal irritation to wounds. Through the synergistic effect of *Broomia spp.* leaf extract, neohesperidin, and scopolamine hydrobromide, a multi-layered closed loop of antioxidant, anti-inflammatory, blood-activating, and repairing effects is formed. Combined with the addition of natural herbal medicines, it can achieve rapid and efficient wound repair.

The application belongs to the technical field of biological fermentation, and particularly discloses a chaga extract with anti-inflammatory and repairing effects, and a preparation method and application thereof. The preparation method of the chaga extract comprises the following steps: (1) strain activation: the frozen chaga is streaked and activated on a solid culture medium; (2) preparation of a seed liquid: the mycelium of the activated chaga is inoculated into a liquid fermentation culture medium to culture a seed liquid; (3) fermentation culture: the seed liquid is inoculated into the liquid fermentation culture medium to culture, and the liquid fermentation culture medium is added with Platycladus orientalis oil to obtain a chaga fermentation liquor; and (4) extraction: the chaga fermentation liquor is extracted to obtain the chaga extract. The chaga extract is prepared by adopting specific culture medium for fermentation treatment and adding specific inducers, so that the content of active ingredients in the extract can be effectively improved, the active effect is good, the chaga extract has good effects in skin repair and anti-inflammation, and can be applied as a raw material in cosmetics or medical products.

This invention discloses a biomimetic transdermal formulation based on Platycladus orientalis leaf exosome-like nanovesicles, its preparation method, and its application. The formulation comprises Platycladus orientalis leaf exosome-like nanovesicles with a surface modified with hyaluronic acid (HA), wherein the hyaluronic acid (HA) is non-covalently bound to the surface of the nanovesicles. This invention, by non-covalently modifying the surface of the Platycladus orientalis leaf exosome-like nanovesicles with HA, effectively improves the particle size uniformity and colloidal stability of the vesicles, and endows them with enhanced hair follicle targeting and cellular uptake capabilities. In this formulation, HA and Platycladus orientalis leaf exosome-like nanovesicles have a synergistic effect, and can exert a multi-component, multi-target, and multi-pathway anti-AGA mechanism through synergistic regulation of multiple signaling pathways and mechanisms, thereby significantly improving the degree of AGA hair loss and significantly increasing the amount of new hair growth.