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260 results about "Artemisia annua" patented technology

Artemisia annua, also known as sweet wormwood, sweet annie, sweet sagewort, annual mugwort or annual wormwood (Chinese: 黄花蒿; pinyin: huánghuāhāo), is a common type of wormwood native to temperate Asia, but naturalized in many countries including scattered parts of North America.

Composition with effects of controlling oil and removing dandruff and application

The invention relates to a composition with oil control and dandruff removal effects and application, and belongs to the technical field of cosmetics. The invention provides a composition with effects of controlling oil and removing dandruff. The composition is prepared from a soapberry fruit extract, a camellia seed extract, an artemisia annua extract, a fructus forsythiae extract, a fructus chebulae extract and an eclipta prostrata extract. Researches show that the composition composed of the components limited in the specific ratio can synergistically improve the 5alpha reductase inhibitory activity and the malassezia inhibitory activity, and the composition has remarkable oil control, bacteriostasis and dandruff removal effects. Furthermore, after the shampoo prepared from the composition provided by the invention is used in a short time, the scalp grease secretion and dandruff conditions of a subject are obviously improved. Therefore, the composition provided by the invention can efficiently regulate and control scalp micro-ecology and sebum secretion, remarkably reduce dandruff generation and realize the effects of controlling oil and removing dandruff.
Owner:SOFYA BIOTECHNOLOGY CO LTD

A soothing, moisturizing and repairing composition and its application

The present invention provides a soothing, moisturizing and repairing composition and its application, which relates to the technical field of daily chemicals. The present invention has a soothing, moisturizing and repairing composition with Artemisia annua extract, Centella asiatica extract and Gentiana yunnanensis extract as main components, and the raw materials are selected from natural ingredients such as Artemisia annua, Centella asiatica, Gentiana yunnanensis, etc., which is non-toxic and non-irritating to human skin and has high safety; further, the product of the present invention can be used to repair skin damage caused by various reasons, and has anti-inflammatory and moisturizing effects. It is applied to cosmetics and skin care products, such as gel, emulsion, cream, essence, etc., which is gentler to the human body, safe and non-irritating.
Owner:DOCTOR PLANT GUANGDONG BIOTECHNOLOGY CO LTD

A pet sterilizer and deodorant

The present invention relates to a pet sterilizer and deodorizer, which belongs to the technical field of pet deodorization. The present invention promotes the long-term expression of hop extract and enhances the sterilization and deodorization effect through the synergistic effect of hop extract, persimmon tannin, and lysozyme. Furthermore, the composition is stable, natural, and pollution-free, and can be used in the oral cavity and in vitro of animals. The present invention also provides zinc ricinoleate and an antibacterial agent. Through the three-phase interaction of zinc ricinoleate, hop extract, and antibacterial agent, the overall stability is enhanced and the antibacterial time of the complex is prolonged while ensuring antibacterial and deodorizing effects. The present invention also provides a modified quaternary ammonium salt antibacterial liquid. The modified quaternary ammonium salt has enhanced stability and, when present together with zinc ricinoleate, promotes an enhanced deodorizing effect. The present invention also provides an Artemisia annua extract, a Gentiana root extract, and an Artemisia argyi extract, which can eliminate odor sources and significantly inhibit bacterial growth, thereby having significant antibacterial, deodorizing, and odor-removing effects.
Owner:FOSHAN FODAN ANIMAL PHARM CO LTD

Preparation method and application of artemisia apiacea fermentation extracting solution

The invention discloses a preparation method and application of an artemisia apiacea fermentation extracting solution. The artemisia annua fermentation extracting solution is prepared from artemisia annua, ultrapure water, probiotics and the like. The preparation method comprises the following steps: picking fresh artemisia annua, cleaning, drying and sterilizing; crushing, sieving, and selecting artemisia annua particles with proper particle sizes; adding the selected artemisia annua particles, ultrapure water and probiotics into a temperature-controlled closed stirring reaction device, and carrying out strict anaerobic fermentation; separating a liquid phase part and a solid phase part from the obtained fermentation product through five filtering processes, performing microfiltration on the liquid phase part to remove thalli, and adding 1, 2-hexanediol and p-hydroxyacetophenone to obtain the artemisia apiacea fermentation extracting solution. The extracting solution prepared by fermenting natural plant raw materials and probiotics is high in molecular weight uniformity and high in physiological activity, retains the functional effect of sweet wormwood, is safe, low in sensitivity and low in irritation, and is suitable for being added into various daily chemical products.
Owner:朱灵水

Application of Artemisia apiacea AaU6 promoter in CRISPR / Cas9 gene editing and gene editing method

The invention belongs to the technical field of gene engineering, and relates to application of an artemisia apiacea AaU6 promoter in CRISPR / Cas9 gene editing and a gene editing method, the promoter comprises AaU6-1, AaU6-4 and AaU6-8, the nucleotide sequence of the AaU6-1 is as shown in SEQ ID NO.1, the nucleotide sequence of the AaU6-4 is as shown in SEQ ID NO.2, and the nucleotide sequence of the AaU6-8 is as shown in SEQ ID NO.3. The invention also relates to an application of the artemisia apiacea AaU6 promoter in CRISPR / Cas9 gene editing. The promoter AaU6-1, the promoter AaU6-4 and the promoter AaU6-8 are utilized, sgRNA expression can be efficiently driven, the editing efficiency of a CRISPR / Cas9 gene editing system is improved, and great significance is achieved for breeding of sweet wormwood.
Owner:SHANGHAI JIAOTONG UNIV

Composition for preventing and treating rice sheath blight disease and preparation method thereof

The invention relates to the technical field of biological prevention and treatment, and discloses a composition for preventing and treating rice sheath blight disease, which is prepared from the following raw materials in parts by weight: 80 to 90 parts of validamycin, 30 to 45 parts of traditional Chinese medicine extract paste, 10 to 20 parts of traditional Chinese medicine raw medicine, 15 to 19 parts of white carbon black, 10 to 17 parts of copper sulfate, 12 to 16 parts of chitosan, 9 to 15 parts of gibberellin, 5 to 9 parts of tebuconazole, 1 to 5 parts of compound sodium nitrophenolate, 2 to 4 parts of emulsifier and 1 to 3 parts of synergist. Gleditsia sinensis, sanguisorba officinalis, flos rhododendri mollis and sapindus mukorossi peel in the traditional Chinese medicine raw medicines are used for synergistically killing bacteria, enhancing the immunity of plants and delaying the decomposition of validamycin, and meanwhile, extracts of honeysuckle, dandelion, croton and artemisia annua in the traditional Chinese medicine extract are complementary with validamycin in the aspects of sterilization, virus resistance and plant resistance improvement; therefore, the effect of validamycin is more durable, the duration of single application is longer, and the manpower and material resource cost is saved.
Owner:INST OF PLANT PROTECTION JIANGXI ACAD OF AGRI SCI +1

Composition for relieving redness and relieving inflammatory chromophore as well as preparation method and application of composition

The invention belongs to the technical field of cosmetics, and discloses a composition for relieving redness and inflammatory color deposition as well as a preparation method and application of the composition. The composition comprises the following components: a plant extract and a derivative thereof, zinc salt, a resorcinol derivative and protein, the plant extract and the derivative thereof comprise at least one of an artemisia apiacea extract and a derivative thereof, and a glycyrrhiza inflate extract. The artemisia apiacea extract and the derivative thereof and / or the glycyrrhiza inflate extract, the zinc salt, the resorcinol derivative and the protein are reasonably compounded, so that red, swollen and discomfort in the inflammation period can be relieved, repair of damaged skin can be promoted, color sink after inflammation can be reduced, and scar generation can be inhibited; meanwhile, the composition is mild and non-irritant, and is suitable for sensitive skin and damaged skin.
Owner:GUANGZHOU HUANYA COSMETIC SCI & TECH CO LTD

Traditional Chinese medicine composition for treating cold as well as preparation method and application thereof

PendingCN120078872AAntibacterial agentsNervous disorderBelamcanda chinensisBistorta officinalis
The invention belongs to the technical field of traditional Chinese medicine research, and particularly relates to a traditional Chinese medicine composition for treating cold and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 7-11 parts of cistanche, 10-14 parts of dried ginger, 7-11 parts of pogostemon cablin, 13-17 parts of pericarpium citri reticulatae, 10-14 parts of polygonum cuspidatum, 7-11 parts of bistort rhizome, 8-12 parts of fructus forsythiae, 28-32 parts of honeysuckle, 10-14 parts of radix bupleuri, 10-14 parts of blackberry lily, 8-12 parts of notopterygium root, 7-11 parts of radix angelicae pubescentis, 7-11 parts of divaricate saposhnikovia root, 7-11 parts of schizonepeta, 7-11 parts of radix angelicae, 10-14 parts of fingered citron, 7-11 parts of perilla stem, 13-17 parts of artemisia apiacea and 10-14 parts of folium mori. The traditional Chinese medicine composition has a better curative effect on cold-dampness cold.
Owner:新疆医科大学第四附属医院

Micro-capsule acne removal cream and preparation method thereof

PendingCN119632901ARefreshing skingood skin feelCosmetic preparationsAntibacterial agentsETHYLHEXYL HYDROXYSTEARATEEthyl group
The invention relates to the field of skin care products, in particular to micro-capsule acne removal cream and a preparation method thereof. The micro-capsule acne-removing cream is prepared from the following components: a humectant, a skin conditioner, a suspending agent, a pH regulator and aloe barbadensis leaf water, behenyl alcohol, arachil alcohol, stearic acid, ethylhexyl hydroxystearate, an artemisia annua extract, pentaerythritol tetrakis (ethylhexanoate) ester, polydimethylsiloxane, tocopheryl acetate and squalane are used as raw materials; and carbomer. The anti-acne cream provided by the invention has the novel appearance of transparent gel and coated particles, can form a micro-capsule structure, and has the advantages of enhancing the anti-acne effect and fully exerting the effects of active substances.
Owner:GUANGZHOU TINGCAI COSMETICS CO LTD

Artemisia annua cell-derived exosome nano-vesicle and application of inclusion peroxidase A0A2U1N9S9 of exosome nano-vesicle in preparation of anti-colorectal cancer drugs

The invention discloses an application of exosome nano-vesicles derived from artemisia annua cells and peroxidase A0A2U1N9S9 contained in the exosome nano-vesicles in preparation of anti-colorectal cancer drugs. According to the present invention, the anti-CRC activity analysis results show that the artemisia annua cell-derived exosome nano-vesicles can inhibit the growth of DLD-1 and HCT116 cell strains, and the active substance base of ACDENVs for inhibiting the growth of DLD-1 and HCT116 cell strains, namely peroxidase A0A2U1N9S9, is innovatively revealed for the first time based on the difference analysis of the proteomics technology; and a new research thought and a theoretical basis are provided for the research of anti-colorectal cancer drugs.
Owner:JINAN UNIVERSITY

Traditional Chinese medicine composition for treating breast cancer complicated with anxiety disorder as well as preparation method and application of traditional Chinese medicine composition

The invention discloses a traditional Chinese medicine composition for treating breast cancer complicated with anxiety disorder as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is mainly prepared from the following raw material medicines: astragalus membranaceus, herba epimedii, ligusticum wallichii, semen boitae, acanthopanax, rhizoma drynariae, selfheal, arisaema cum bile, turtle shell, nigrum fruit, salvia chinensis and artemisia apiacea. The invention further discloses a preparation method of the traditional Chinese medicine composition, a pharmaceutical preparation and application. Pharmacodynamic experiments prove that the traditional Chinese medicine composition can remarkably inhibit tumor growth of anxiety tumor-bearing mice and improve anxiety behavioral indexes, achieves dual treatment targets of tumor resistance and emotion regulation, and is particularly suitable for middle and advanced breast cancer combined anxiety patient groups needing long-term treatment.
Owner:GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI

Leixihaokang, preparation method therefor, and use thereof

The present invention belongs to the field of traditional Chinese medicines, and particularly relates to Leixihaokang, a preparation method therefor, and use thereof. The Leixihaokang of the present invention is prepared from the following active pharmaceutical ingredients in parts by weight: 10 parts of Tripterygium glycosides and 0.1-1.3 parts of Artemisia annua extract. According to the present invention, animal experiments prove that the Leixihaokang can ameliorate renal damage in nephrotic syndrome caused by adriamycin, reduce the occurrence of proteinuria, and reduce the apoptosis of renal tissue cells. Meanwhile, the Leixihaokang of the present invention has a good inhibitory effect on renal, hepatic, splenic, and cardiac toxicity in the treatment process of nephrotic syndrome. According to the present invention, animal experiments also prove that the Leixihaokang can ameliorate skin injury in imiquimod-induced psoriasis, reduce inflammatory infiltration and alleviate skin damage. Meanwhile, the Leixihaokang has a certain degree of inhibitory effect on the hepatic and reproductive system toxicity in the treatment process of psoriasis.
Owner:GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE +2

Multi-effect collagen composition suitable for sensitive skin and application thereof

The invention relates to the technical field of daily chemicals, in particular to a collagen composition suitable for sensitive skin and having multiple effects and application of the collagen composition. The composition comprises the following components: a haw fruit extract, a ginseng root extract, an artemisia annua extract and a centella asiatica extract. The collagen face cream with multiple effects on sensitive skin provided by the invention is mild and skin-friendly, is suitable for people with sensitive skin, selects a low-irritation emulsification system and high-skin-friendly grease, does not contain alcohol, sensitization essence and high-sensitization preservative, has the pH value regulated between 5.2 and 6.0, is close to the slightly acidic environment of human skin, and has the advantages of mild skin-friendly effect, mild skin-friendly effect and good skin-care effect. The irritation and burden on sensitive skin are effectively reduced.
Owner:ZHEJIANG NAJI BIOTECHNOLOGY CO LTD

Soothing and oil-controlling composition derived from natural plants and application of soothing and oil-controlling composition

PendingCN121754458AReduce acne conditionBreak the vicious cycleCosmetic preparationsToilet preparationsBiotechnologyCalendula officinalis extract
The invention discloses a soothing and oil-controlling composition derived from natural plants and application thereof, and belongs to the technical field of daily cosmetics. The composition is formed by compounding an artemisia annua extract, a rehmannia root extract, a calendula extract and a pomelo fruit extract, and the four plant extracts have a synergistic effect, have the effects of repairing, relieving and controlling oil, and can be used for preparing a skin care product special for oil-sensitive skin. The composition provided by the invention can effectively solve the problems of external oil and internal dry, redness and sensitivity, grease accumulation and the like of oily sensitive skin, and meets multiple skin care requirements.
Owner:BEIJING PLANT DOCTOR BIOTECHNOLOGY CO LTD +1

Traditional Chinese medicine composition for preventing and treating metabolism-related fatty liver diseases or metabolic syndromes

The invention discloses a traditional Chinese medicine composition for preventing and treating metabolism-related fatty liver diseases or metabolic syndromes. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 5-50 parts of sweet wormwood, 3-30 parts of scutellaria baicalensis, 5-50 parts of dandelion, 4-60 parts of platycodon grandiflorum, 5-50 parts of fructus aurantii, 3-80 parts of rhizoma pinelliae preparata, 3-70 parts of fructus amomi, 10-80 parts of stir-fried Chinese yam, 5-80 parts of poria cocos and 3-100 parts of raw coix seeds. The traditional Chinese medicine composition for preventing and treating the metabolism-related fatty liver diseases or the metabolic syndromes is simple in formula, proper in compatibility and mild in medicine property, is used for preventing and treating the metabolism-related fatty liver diseases or the metabolic syndromes, is used for improving liver fatty degeneration and inflammation, blood uric acid, blood fat, blood sugar and blood pressure, assisting weight loss and the like, and is safe to use and remarkable in curative effect.
Owner:BEIJING UNIV OF CHINESE MEDICINE

Tightening, anti-wrinkle, soothing and repairing mask liquid, preparation method and mask product

The invention relates to the technical field of cosmetics, and discloses a firming, anti-wrinkle, soothing and repairing mask liquid. The mask liquid is prepared from the following components in percentage by mass: 1 to 2 percent of agave extract, 0.5 to 1 percent of herba portulacae extract, 0.5 to 1 percent of oriental cherry extract, 1 to 2 percent of tremella extract, 0.5 to 1 percent of melia azedarach leaf extract, 0.5 to 1 percent of spirulina platensis, 0.5 to 1 percent of ginkgo leaf extract, 0.5 to 1 percent of artemisia annua extract, 0.1 to 0.5 percent of sodium hyaluronate, 1 to 2 percent of trehalose, 1 to 3 percent of collagen, 0.5 to 1 percent of panthenol and the balance of water. 0.1-0.3% of a stabilizer, 1-2% of a preservative, 5-8% of glycerol, 3-5% of propylene glycol and the balance of water. According to the invention, a plurality of natural components are compounded to achieve a synergistic effect, and a comprehensive skin care effect is provided for tightening, resisting wrinkles, soothing and repairing.
Owner:HANGZHOU LAILAI TECHNOLOGY CO LTD

Nano-liposome emulsion with moisturizing effect prepared by microjet method and preparation method of nano-liposome emulsion

The invention belongs to the technical field of cosmetics, particularly discloses moisturizing nano-liposome emulsion prepared by a microjet method and a preparation method of the moisturizing nano-liposome emulsion, and aims to solve the problems of poor stability of active ingredients, low transdermal absorption efficiency, single effect and non-uniform particle size in a liposome preparation process in the existing moisturizing cosmetics. The nano-liposome emulsion is prepared from glycosylglycerol, acetylchitosamine, tremella polysaccharide, a myrothamnus flabellifolia leaf / stem extract, an artemisia annua extract, a lactobacillus fermentation product, flat nuclear wood oil, hydrogenated lecithin and phosphatidylcholine. The emulsion has excellent moisturizing, soothing and repairing effects, can be used for preparing skin care products such as water aqua, emulsion and cream, and has the advantages of high utilization rate of active ingredients and good stability.
Owner:HAOYU (GUANGZHOU) COSMETICS MFG CO LTD +1

Anti-HPV (human papillomavirus) temperature-sensitive gel as well as preparation method and application thereof

The invention provides an anti-HPV (human papillomavirus) temperature-sensitive gel as well as a preparation method and application thereof. The invention provides the anti-HPV temperature-sensitive gel as well as the preparation method and application thereof. The gel consists of a natural active extract, a temperature-sensitive polymer, a cross-linking agent and a stabilizer, wherein the natural active extract comprises a mixture of a sophora flavescens extract, an artemisia annua extract and a mushroom extract in a specific mass ratio. These extracts are obtained by specific extraction processes to ensure their antiviral activity. The thermo-sensitive polymer is a mixture of poly (N-isopropylacrylamide) and hydroxypropyl methyl cellulose, and the cross-linking agent and the stabilizer are used for enhancing the performance of the gel. The preparation method of the gel comprises the following steps: preparing a natural active extract emulsion, preparing a wall material solution, emulsifying and microencapsulating, so as to finally form the gel with temperature sensitivity. The gel has specific rheological properties at body temperature, can be used for treating HPV infection, and provides a new local treatment method.
Owner:GUANGZHOU GREENWALL BIOMEDICAL TECH CO LTD

Micro-ecological preservative composition suitable for sensitive skin

The invention provides a micro-ecological preservative composition suitable for sensitive skin. The preparation method comprises the following steps: firstly, carrying out reflux extraction on artemisia apiacea through 60% ethanol, then adding lactobacillus plantarum and saccharomyces cerevisiae for fermentation to obtain artemisia apiacea fermentation liquor powder, and then compounding phenoxyethanol and gluconolactone to obtain the micro-ecological preservative composition. Experiments prove that the micro-ecological preservative composition does not excessively inhibit / promote proliferation of propionibacterium acnes, disturbance and damage to resident bacterial colonies of skin are reduced, and the micro-ecological preservative composition has a certain repairing effect on a micro-ecological barrier. Phenoxyethanol and natural preservatives (sweet wormwood herb fermentation liquor powder and gluconolactone) have a certain synergistic preservative effect, so that the dosage of phenoxyethanol can be reduced, and the irritation and scorching risks of high use concentration of phenoxyethanol to sensitive skin are reduced.
Owner:SHANDONG FREDA BIOTECH CO LTD

Artemisia annua fat-soluble extract as well as preparation method and application thereof

The invention relates to the technical field of extraction of fat-soluble components in artemisia annua, and particularly discloses an artemisia annua fat-soluble extract as well as a preparation method and application thereof. The invention relates to a preparation method of an artemisia annua fat-soluble extract. The preparation method comprises the following steps: 1, preparing artemisia annua powder from artemisia annua leaves; step 2, soaking the artemisia annua powder into a composite solvent formed by mixing ethanol, normal hexane, petroleum ether, succinic acid and pentanediol, extracting, and collecting an extracting solution; step 3, repeating the operation in the step 2 for 2-3 times, and combining extract liquor to obtain a primary extract of the artemisia annua; and step 4, dewaxing to obtain the artemisia annua extract. According to the method, a composite solvent system is adopted, fat-soluble components including sesquiterpene lactone and flavonoid active substances in artemisia annua can be comprehensively extracted, and loss of the active components in a traditional method is effectively avoided.
Owner:XIAN LUOJIA BIOTECHNOLOGY CO LTD

Natural plant oil-controlling and acne-removing composition as well as preparation method and application thereof

InactiveCN119454547ACosmetic preparationsToilet preparationsBiotechnologyMARSHMALLOW ROOT
The invention relates to the technical field of cosmetic raw materials, and particularly discloses a natural plant oil-control acne-removal composition as well as a preparation method and application thereof. The natural plant oil control and acne removal composition comprises the following components in parts by mass: 8.45-29.7 parts of a humectant; 0.2-2 parts of a preservative; 11.65 to 28 parts of a composite extract; 40.3 to 79.7 parts of a solvent; the compound extract is prepared by compounding a fructus forsythiae fruit extract, a pueraria mirifica extract, blumea balsamifera oil, an althaea officinalis root extract, a rhizoma kaempferiae root extract and an artemisia annua extract. According to the present invention, the acne removing product has advantages of good acne removing effect and irritation reducing.
Owner:GUANGZHOU BABY-MUM BIOLOGICAL TECH CO LTD

Traditional Chinese medicine compound exosome for treating ovarian cancer as well as preparation method and application thereof

The invention discloses a traditional Chinese medicine compound exosome for treating ovarian cancer and a preparation method and application thereof. The preparation method of the traditional Chinese medicine compound exosome comprises the following steps: (1) soaking the raw material medicines in the traditional Chinese medicine compound in deionized water, boiling with big fire, and decocting for 35-45 minutes; then adjusting to slow fire, and continuously decocting for 30-35 minutes to obtain the traditional Chinese medicine compound water decoction. (2) preparing the traditional Chinese medicine compound exosome from the traditional Chinese medicine compound water decoction by an ultracentrifugation method; wherein the traditional Chinese medicine compound comprises the following raw material medicines: astragalus membranaceus, bighead atractylodes rhizome, cinnamon, curcuma zedoary, fructus lycii, seaweed, pericarpium citri reticulatae viride, lindera aggregata, turtle shell, oldenlandia diffusa, scorpio, artemisia apiacea, arisaema cum bile, edible tulip and radix ranunculi ternati. The prepared traditional Chinese medicine compound exosome can be used for treating ovarian cancer, and the curative effect of the exosome is superior to that of a traditional traditional Chinese medicine compound administration mode.
Owner:GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI

Plant anti-dandruff composition with oil control and antibacterial efficacy and application thereof

The present application relates to a kind of plant anti-dandruff composition with oil control and bacteriostasis efficacy and application thereof, belong to the field of cosmetics.The composition includes soapberry fruit extract, camellia seed extract, artemisia annua extract, valerian root extract, phyllanthus emblica fruit extract;The valerian root extract is extracted after being inoculated with mixed inoculant consisting of bacillus licheniformis and lactobacillus bulgaricus and then fermented with valerian root as raw material.The valerian root extract obtained by the fermentation of specific strains and strain ratio mixture is significantly improved in the bacteriostatic effect on malassezia and propionibacterium acnes.Further, the present application selects specific soapberry fruit extract, camellia seed extract, artemisia annua extract, phyllanthus emblica fruit extract and the obtained valerian root extract within a specific proportion range, and the obtained composition has synergistic effect of each component, which can significantly improve its oil control, bacteriostasis and anti-dandruff effect.
Owner:SOFYA BIOTECHNOLOGY CO LTD

Plant-derived exosome-encapsulated drug-loaded calcium-based nanogenerator, preparation method thereof and anti-tumor application thereof

The present application relates to a kind of plant source exosome-encapsulated drug-loaded calcium-based nanogenerator and preparation method and its application, the nanogenerator includes drug-loaded core, the drug-loaded core outside is coated with plant source exosome shell layer;Wherein, the plant source exosome shell layer is selected from one or more of curcuma source exosome, broccoli source exosome, artemisia annua source exosome, camellia source exosome.This nanogenerator of the present application has the ability of enhancing calcium overload and amplifying cell oxidative stress, the generator can improve the stability and biocompatibility of CaO2 While, overcome tumor cell antioxidant defense mechanism.By curcuma source exosome as protective layer wrapped outside CaO2, solve the problem of CaO2 In vivo blood circulation stability and dispersibility, increase the efficiency of the nanogenerator into tumor cell.
Owner:SUN YAT SEN UNIVERSITY SHENZHEN +1

Artemisia annua extract, its preparation method and application and artemisia annua extract veterinary medicine

The application discloses a sweet wormwood extract, a preparation method and application thereof and a sweet wormwood extract veterinary drug, and the method comprises the following steps: S1, heating and extracting sweet wormwood byproducts with an extraction solvent, filtering, discarding the filtrate, and obtaining an intermediate product filter cake; S2, concentrating the intermediate product filter cake to a constant weight; S3, heating and extracting the constant weight obtained in the step S2 with deionized water, filtering, and taking the filtrate; S4, concentrating the filtrate obtained in the step S3 to a constant weight, and obtaining the sweet wormwood extract. The application provides a sweet wormwood extract and a preparation method thereof, and provides a veterinary drug based on the sweet wormwood extract; the veterinary drug obtained by the application can clear heat, resolve summer-heat, and relieve deficiency heat, and can be used for treating various livestock and poultry diseases; the preparation method is simple, easy to operate, raw materials are easy to obtain, production cost is low, and the application has a good market application prospect.
Owner:苏州满元生物科技有限公司

An anti-cracking repair composition containing artemisia annua and camellia seed oil, its preparation and application

The present invention specifically relates to an anti-cracking and repairing composition containing artemisia annua and camellia seed oil, and its preparation and application, belonging to the technical field of cosmetics. The composition of the present invention is prepared by using allantoin, phenoxyethanol, ethylhexylglycerin, artemisia annua extract, urea, tocopherol, camellia seed oil, PEG / PPG-14 / 7 dimethyl ether, cholesteryl polyether-10, portulaca oleracea extract, taraxacum extract, grape seed oil, squalane, caprylic / capric triglyceride, bis(lauroyl glutamine) lysine sodium, glycerin, butanediol, carrageenan, sodium carboxymethyl cellulose and water. The cooperation among the raw materials enables the composition to have excellent anti-chapping, skin repairing and nursing, and anti-inflammatory and soothing effects, and at the same time has good stability and safety effects.
Owner:YUNNAN QUNYOU BIOTECHNOLOGY CO LTD

Purification device and purification method for artemisia annua oil processing

The present invention provides a purification device and purification method for processing artemisia annua oil. The purification device comprises a fixed seat, a circular ring is installed on the fixed seat, a rotating ring is rotated inside the circular ring, a gear ring a is installed on the rotating ring, a rotating driving member a is installed on the fixed seat, a gear a is installed on the output end of the rotating driving member a, and the gear a is meshed with the gear ring a; a connecting block is installed on the rotating ring. The present invention drives the swing plate to fold up, drives it to enter the first area along the circular groove, drives the closing plate to close the circular groove, and the rotating driving member a drives the rotating ring to rotate, drives the purification tank to rotate to an inclined state, at which time the drainage port is at the lowest point; drives the circular extrusion plate to move downward, drives the circular extrusion plate to squeeze the crushed artemisia annua raw material, and the squeezed artemisia annua oil enters the first area along the filter hole, and then is discharged through the drainage port under the action of gravity, thereby completing the purification of artemisia annua oil.
Owner:YONGZHOU XINGCHEN BIOTECH CO LTD

Artemisia annua wet wipes bag

ActiveCN309323037SWet wipeArtemisia annua
1. The name of the product of this design: Artemisia annua wet wipes bag. 2. Purpose of this design product: used for packaging wet wipes. 3. The design key points of this appearance design product are: the combination of shape, pattern and color. 4. The picture or photo that best illustrates the key points of the design: main view. 5. The design for which protection is sought includes color. 6. The left and right sides of the product have been expressed in other views, so the left and right views are omitted.
Owner:JIANGXI LONGKING TECH CO LTD

Beta-farnesene synthase mutant and application thereof

The invention discloses a beta-farnesene synthase mutant, which is characterized in that the amino acid sequence of the beta-farnesene synthase mutant has the difference of one or more amino acid residues selected from A26T, A169E, Y251H, V323S, G325A and A438T relative to the amino acid sequence of wild type beta-farnesene synthase derived from walnuts. The beta-farnesene synthase mutant gene and the encoding protein thereof provided by the invention are effectively expressed in saccharomyces cerevisiae. Under the same condition, the walnut-derived beta-farnesene synthase mutant provided by the invention not only has higher activity compared with the beta-farnesene synthase derived from artemisia annua, German chamomile, peppermint and fragrant citrus, but also has significantly improved enzyme activity compared with the wild walnut beta-farnesene synthase; and the saccharomyces cerevisiae can have higher farnesene yield.
Owner:SHANGHAI HUIWEN BIO TECH

A traditional Chinese medicine composition for improving systemic lupus erythematosus and a preparation method thereof

The application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for improving systemic lupus erythematosus and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15-30 parts of dry rehmannia, 12-26 parts of calcined turtle shell, 13-25 parts of chicken tendon ginseng, 11-18 parts of red peony root, 10-20 parts of white flower snake tongue grass, 6-18 parts of small rosmarinus officinalis, 4-15 parts of artemisia annua, 5-10 parts of centella asiatica, 4-12 parts of cimicifuga foetida, 3-10 parts of coix seed, 2-9 parts of bergamot slice, and 3-7 parts of raw licorice. Test results show that the traditional Chinese medicine composition for improving systemic lupus erythematosus prepared by the application can inhibit the expression of IL-10 and IL-17 in serum, reduce anti-dsDNA antibodies in serum, significantly improve the clinical symptoms of systemic lupus erythematosus, and has a wide application prospect.
Owner:HANGZHOU THIRD PEOPLES HOSPITAL (HANGZHOU HUIMIN HOSPITAL HANGZHOU THIRD AFFILIATED HOSPITAL OF ZHEJIANG UNIV OF TRADITIONAL CHINESE MEDICINE)