Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of raja porosa extract in alcoholic brain damage protection medicine

An extract and alcohol-based technology, which is applied in the application field of the extract of the stingray in the protection medicine for alcohol-induced brain injury, can solve the problems that the effect of alcohol-induced brain injury has not been reported, etc.

Inactive Publication Date: 2015-12-30
QINGDAO UNIV
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Yellow and Bohai seas are found all year round, with large output, and are important fishery catch objects. The endoskeleton is all cartilage, and the fin rays are horny fin rays. The inventor extracts the ray extract from the ray cartilage, and It is confirmed that the extract has a protective effect on alcoholic liver injury (see ZL201310513265.7), but its effect on alcoholic brain injury has not been reported

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Embodiment 1: the preparation of preparation

[0011] (1) Preparation of the capsule preparation of the ray extract of the present invention

[0012] Weigh 100 mg of the ray extract prepared in the above steps, 395 mg of starch, and 5 mg of magnesium stearate, mix them uniformly, and fill them into capsules.

[0013] (2) Preparation of the ray extract tablet of the present invention

[0014] Weigh 100 mg of ray extract, 295 mg of starch, and 100 mg of lactose prepared in the above steps, mix them uniformly, granulate them by wet method, dry them, mix them with 5 mg of magnesium stearate after granulation, and press them into tablets.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to application of raja porosa extract in alcoholic brain damage protection medicine. The raja porosa extract is extracted from raja porosa cartilage and can improve the activity of SOD and GSH-PX in the brain tissue of rats with chronic alcoholism, reduce MDA and beta-EP in the brain tissue, the protection effect on the brain damage of the rats with chronic alcoholism is achieved, the raja porosa extract can be prepared into various dosage forms and can serve as an alcoholic brain damage protecting agent, and the raja porosa extract has the advantages of being remarkable in curative effect, free of side effects, low in price, safe and convenient to use.

Description

technical field [0001] The invention relates to the application of the ray extract in the protection medicine of alcoholic brain injury. Background technique [0002] Alcoholism is a state in which the central nervous system changes from excitement to inhibition caused by excessive drinking. Long-term heavy drinking can cause damage to multiple organs throughout the body, especially to the brain. Alcoholism and addiction have become a worldwide social problem that seriously endangers human health. [0003] When a large amount of alcohol accumulates in the body and exceeds the catabolic capacity of the liver, it can be directly absorbed into the blood. Alcohol is a lipophilic small molecule chemical substance that easily acts on the brain through the blood-brain barrier. It has been reported in the literature that alcoholism can cause cerebrovascular lesions to affect cerebral blood flow, resulting in changes in ischemia and hypoxia, which may be one of the mechanisms of bra...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K35/60A61P25/00
Inventor 高华刘坤王威于兹东刘小红石振艳
Owner QINGDAO UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com