A traditional Chinese medicine composition with significant effect of sobering up alcohol and protecting liver and preparation method thereof
A technology for sobering up and protecting the liver and composition, which is applied in the directions of drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., and can solve the problems of alcoholism and discomfort symptoms without exact effects, unknown effects of traditional Chinese medicines, unclear pharmacological effects, etc. The problem is to achieve the effect of improving the activity of enzymes related to alcohol metabolism, no toxic and side effects, and a simple preparation method.
Active Publication Date: 2022-06-03
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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Problems solved by technology
[0004] The technical problem to be solved by the present invention is to overcome that the existing western medicine has no definite effect on most of the discomfort symptoms of alcoholism, and it is easy to cause various adverse reactions; the effect of traditional Chinese medicine on inflammatory damage is unknown, the effect is limited, and the pharmacology The defects and insufficiencies of the medicinal effects provide a traditional Chinese medicine composition with a significant function of sobering up and protecting the liver
Method used
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Experimental program
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Embodiment 1
[0055] The experimental results are shown in Tables 1 to 2 and Figure 1.
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[0060]
Embodiment 2
[0076] The experimental results are shown in Tables 3 to 4 and Figure 2.
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[0081]
Embodiment 3
[0101] After the liver tissue was fixed in 4% paraformaldehyde for 24 to 48 hours, it was successively dehydrated, transparent, dipped in wax, and embedded;
[0103] The experimental results are shown in Figures 3-7.
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The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a traditional Chinese medicine composition with a significant function of sobering up and protecting the liver and a preparation method thereof. The traditional Chinese medicine combination is prepared by decocting Chinese medicine raw materials such as Gansong, Codonopsis pilosula, Chinese yam, Chuanxiong, clove, ginger pinellia, white peony root, lotus pod, gastrodia elata, mustard seed, mung bean, jujube, ginger, and licorice according to a certain weight ratio. It is proved by experiments that the traditional Chinese medicine composition of the present invention can significantly improve the activity of enzymes related to alcohol metabolism and inhibit the expression of inflammatory factors, so as to significantly sober up and protect the liver, and improve the effects of symptoms such as dizziness, nausea, abdominal distension and abdominal pain in acute and chronic alcoholism; On the other hand, the traditional Chinese medicine used in the present invention has a wide range of sources, is green and safe, basically has no toxic and side effects on the body, has a simple preparation method, and is convenient to use, and is very suitable for the prevention and treatment of diseases such as alcoholism and liver injury in clinical practice.
Description
A kind of traditional Chinese medicine composition with significant effect of sobering up and protecting liver and preparation method thereof technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions. More specifically, it relates to a kind of drug with significant sobering and hepatoprotective effect. Traditional Chinese medicine composition and preparation method thereof. Background technique In recent years, along with the improvement of our country's living standard, alcohol consumption increases year by year, and simultaneously, our country is due to excessive intake of alcohol. Acute alcoholism caused by sperm and related diseases caused by acute and chronic alcohol intake are increasing. After alcohol is ingested in the human body, the main To be absorbed through the gastric mucosa (25%) and the intestinal tract (75%), most of the ethanol is metabolized by internal oxidation in the liver, and ethanol first...
Claims
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IPC IPC(8): A61K36/9068A61P39/02A61P1/16
CPCA61K36/84A61K36/344A61K36/8945A61K36/236A61K36/61A61K36/8888A61K36/71A61K36/65A61K36/62A61K36/8988A61K36/31A61K36/48A61K36/725A61K36/9068A61K36/484A61P39/02A61P1/16A61K2236/331A61K2236/39A61K2236/51A61K2300/00Y02A50/30
Inventor 何金洋谢磊黄文冠陈桂蓉李俊霖王奇
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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