A traditional Chinese medicine composition for treating chronic alcoholic liver disease

A composition and alcohol technology, applied in the field of medicine, to achieve the effects of good application prospects, easy availability of raw materials, and comprehensive drug effects

Active Publication Date: 2015-10-07
NANTONG FINC PHARMA CHEM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is challenging for people to seek single-drug active ingredients or compound prescriptions from traditional Chinese herbal medicines to treat cancer

Method used

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  • A traditional Chinese medicine composition for treating chronic alcoholic liver disease
  • A traditional Chinese medicine composition for treating chronic alcoholic liver disease
  • A traditional Chinese medicine composition for treating chronic alcoholic liver disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1 Chinese medicine composition mixture of the present invention

[0034] Prescription: 10 parts of Alisma, 15 parts of Fangji, 6 parts of Yinchen, 10 parts of Polygonum multiflorum, 10 parts of Chuanxiong, 6 parts of Angelica, 20 parts of Citrus aurantium, 20 parts of gallnut, 10 parts of Bupleurum, 12 parts of Polygonatum, 15 parts of Scutellaria baicalensis , 30 parts of wolfberry, 6 parts of poria cocos, 10 parts of licorice.

[0035] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 75% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol to concentrate, ad...

Embodiment 2

[0036] Embodiment 2 Chinese medicine composition tablet of the present invention

[0037] Prescription: 10 parts of Alisma, 15 parts of Fangji, 6 parts of Yinchen, 10 parts of Polygonum multiflorum, 10 parts of Chuanxiong, 6 parts of Angelica, 20 parts of Citrus aurantium, 20 parts of gallnut, 10 parts of Bupleurum, 12 parts of Polygonatum, 15 parts of Scutellaria baicalensis , 30 parts of wolfberry, 6 parts of poria cocos, 10 parts of licorice.

[0038] Preparation method: Take each medicinal material of the above weight components, add water 10 times the total weight of the medicinal materials, soak for 60 minutes, decoct once, 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.25 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 80% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol until concentrated, vacu...

Embodiment 3

[0039] Embodiment 3 Chinese medicine composition capsule of the present invention

[0040] Prescription: 10 parts of Alisma, 15 parts of Fangji, 6 parts of Yinchen, 10 parts of Polygonum multiflorum, 10 parts of Chuanxiong, 6 parts of Angelica, 20 parts of Citrus aurantium, 20 parts of gallnut, 10 parts of Bupleurum, 12 parts of Polygonatum, 15 parts of Scutellaria baicalensis , 30 parts of wolfberry, 6 parts of poria cocos, 10 parts of licorice.

[0041]Preparation method: Take the medicinal materials of the above weight components, add water 8 times the total weight of the medicinal materials, soak for 45 minutes, decoct 4 times for 1.5 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.2 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 90% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol to concentrate, v...

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Abstract

The invention belongs to the technical field of medicine, relates to a traditional Chinese medicine composition, and in particular relates to a traditional Chinese medicine composition for treating chronic alcoholic toxic liver disease and a preparation method thereof. Aiming at the current technical defects of lack of comprehensive and effective treatment on the chronic alcoholic toxic liver disease, easiness in relapse of chemical treatment, and inconstant curative effect, the invention provides the traditional Chinese medicine composition for treating chronic alcoholic toxic liver disease. The traditional Chinese medicine composition comprises the following components: 10 parts of rhizoma alismatis, 15 parts of Fourstamen Stephania root, 6 parts of herba artemisiae, 10 parts of fleece-flower root, 10 parts of rhizoma ligustici wallichii, 6 parts of angelica, 20 parts of hovenia dulcis, 20 parts of Chinese gall, 10 parts of radix bupleuri, 12 parts of rhizoma polygonati, 15 parts of Scutellaria baicalensis, 30 parts of Lycium barbarum L., 6 parts of Poria cocos, and 10 parts of liquorice. The traditional Chinese medicine composition has a very good treatment effect in the treatment of chronic alcoholic toxic liver disease, and has significant clinical promotion value.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine composition and its application as a medicine for treating chronic alcoholic liver disease. Background technique [0002] Chronic alcoholic liver disease is a common disease in modern society. Long-term excessive drinking can cause fatty degeneration, necrosis and regeneration of liver cells repeatedly through ethanol itself and its derivative acetaldehyde, leading to chronic alcoholic liver disease, including Alcoholic fatty liver, alcoholic hepatitis, liver fibrosis, and cirrhosis. In the early stage of chronic alcoholic liver disease, there are generally no specific symptoms and signs. With the development of the disease, some signs of digestive system and liver disease appear, which will gradually lead to alcoholic hepatitis, liver fibrosis, and liver cirrhosis. Mild symptoms include abdominal distension, fatigue, discomfort in the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8969A61P1/16A61K35/64
Inventor 刘洪军周东浩
Owner NANTONG FINC PHARMA CHEM
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