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Material for bone tissue engineering scaffold and making method thereof
InactiveCN101032632AImprove mechanical propertiesGood biocompatibilityBone implantBiocompatibility TestingBiological materials
The present invention relates to biological material technology, and is especially porous magnesium, magnesium alloy and composite magnesium material used as high strength biomedicine rack material for human body hard tissue defection and its preparation process. The porous magnesium, magnesium alloy and composite magnesium material used in bone tissue engineering rack has porosity of 5-99 % and pore diameter of 50-900 microns. Owing to easy degradation and absorption of magnesium inside body, the bone tissue engineering rack of porous magnesium, magnesium alloy and composite magnesium material has excellent mechanical performance and excellent biocompatibility and can provide 3D space for cell to grow.
Owner:INST OF METAL RESEARCH - CHINESE ACAD OF SCI
Traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases
InactiveCN106729432AImprove blood weightImprove blood vessel elasticityHeavy metal active ingredientsHydroxy compound active ingredientsAcute hyperglycaemiaCervical spondylosis
The invention discloses a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases. The traditional Chinese medicine composition is mainly prepared from 81 kinds of traditional Chinese medicine such as radix panacis quinquefolii, placenta hominis, radix salvia miltiorrhizae, herba rhodiolae, fructus schisandrae, head of Chinese angelica, rhizoma chuanxiong, radix polygalae, hirudo, radix notoginseng, fried semen ziziphi spinosae, herba cistanches and radix rehmanniae through mutual matching. The traditional Chinese medicine composition is capable of improving general blood circulation, blood weight and blood vessel elasticity within a shorter time, and meanwhile, damp cold in a body and outer walls of blood vessels can be eliminated and removed out of the body in time; the traditional Chinese medicine composition has the function of repairing internal organs such as the liver, the kidney, the lung and the spleen and is capable of increasing the immunity and the disease resistance of the body in time; the traditional Chinese medicine composition has an obvious treatment or auxiliary treatment rehabilitation function on heart disease, cerebral thrombosis, serious insomnia, astriction, hypertension, hyperglycemia, hyperlipidemia, insufficiency of cerebral blood supply, tinnitus, cervical spondylosis and lumbar spondylosis.
Owner:贾庭山
Self-restoration concrete with enhanced restoration property and preparation method thereof
The invention discloses self-restoration concrete with enhanced restoration property and a preparation method thereof, and relates to the technical field of building materials. The self-restoration concrete is prepared from the following raw materials in parts by weight: 176 to 190 parts of cement, 44 to 49 parts of fly ash, 322 to 349 parts of fine aggregate, 409 to 444 parts of coarse aggregate,47.3 to 49.5 parts of water, 0.585 to 1.17 parts of fiber, 3.325 to 3.48 parts of water reduction agent, 22.5 to 27 parts of expander, 4.8 to 9.6 parts of restoration material, and 9.3 to 13.95 partsof water storage material. The self-restoration concrete has the advantages that the crack restoration ability of the self-restoration concrete is enhanced, the crack and slight damage with width ofabout 0.3 mm due to various causes can be continuously restored by self, the anti-cracking property of the self-restoration concrete is enhanced, the growth and development of the cracks are inhibited, the application range of the self-restoration concrete is expanded, and the economy of the concrete is improved.
Owner:SOUTH CHINA UNIV OF TECH
Solid beverage having assisted blood glucose lowering function, and preparation method thereof
InactiveCN106983052AFunction increaseRepair functionNatural extract food ingredientsFood ingredient functionsBiotechnologyTrehalose
The invention relates to a solid beverage having an assisted blood glucose lowering function, and a preparation method thereof, wherein the main function components are three or more than three materials selected from kelp or a kelp extract, potassium alginate (low molecular weight potassium alginate), common yam rhizome or a common yam rhizome extract, Chinese wolfberry or a Chinese wolfberry extract, radix puerariae or a radix puerariae extract, mulberry leaf or a mulberry leaf extract, a polygonatum odoratum extract, a bitter gourd extract, the leaf of cyclocarya paliurus and corn stigma, the auxiliary materials comprise one or more than one materials selected from inulin, resistant dextrin, bean powder, tea powder, pumpkin powder, soybean protein powder, barley leaf powder, oat fiber powder, konjac powder and citrus fiber powder, and the flavoring agent is one or a plurality of materials selected from stevioside, xylitol, fructo oligosaccharide, isomaltitol, sucralose, trehalose, matcha powder, and fruit and vegetable powder. The preparation method comprises: 1, crushing, and screening; 2, weighing; 3, carrying out mixing stirring, or carrying out stirring mixing and granulation; and 4, packaging. The solid beverage of the present invention has advantages of significant blood glucose lowering effect, good safety, and no side effect.
Owner:DALIAN YAWEITE BIOTECH
Heavy-metal-resistant plant growth detoxification accelerant and method for using same
InactiveCN102964177APromote photosynthesisHigh in proteinBiocidePlant growth regulatorsSelenateGrowth plant
The invention discloses a heavy-metal-resistant plant growth detoxification accelerant and a method for using the same. The accelerant is characterized by containing low dose of one of selenate or selenite, wherein an amino acid micro element fertilizer is also added, and the accelerant is sprayed onto the leaves for a plurality of times during a period of 7-40 days before crops are harvested. A method for preparing and the method for using are simple and practicable and are convenient to popularize. By the accelerant, the contents of heavy metals of cadmium, antimonium and the like in the crops can be effectively reduced, the crop yield and quality are improved, and the problem that most people in China insufficiently intake selenium can be relieved through a method of reasonably increasing selenium contents in agricultural products, so that the production safety of the agricultural products in heavy metal pollution regions is effectively guaranteed.
Owner:AGRO ENVIRONMENTAL PROTECTION INST OF MIN OF AGRI
Method for plugging deformation joint of underground engineering concrete structure in vibration disturbing environment
ActiveCN106013259ARepair functionRestoration of waterproof design requirementsArtificial islandsUnderwater structuresStructure of the EarthSealant
The invention provides a method for plugging a deformation joint of an underground engineering concrete structure in a vibration disturbing environment. The method comprises the following steps: 1, adopting a drilling process to inject a cement-based plugging agent doped with chemical materials behind the wall of the underground engineering concrete structure; 2, for a severe water leaking and flowing deformation joint, temporarily adopting a special modified epoxy structural adhesive material and a polyurethane grouting material to carry out pinhole process grouting plugging on water leakage; and 3, at the 150-200mm depth position of the deformation joint, blocking a non-tube cavity in the horizontal direction of the deformation joint, filling the non-tube cavity with a modified non-solid rubber and asphalt grouting material, and mounting a sealant and a steel sandwich plate on the non-tube cavity. According to the presentation of the invention, grouting plugging is carried out on the deformation joint part by adopting the modified non-solid rubber and asphalt grouting material, and by adopting the special modified epoxy structural adhesive material, when grouting plugging is carried out on a tiny deformation joint part, reinforcement is also carried out, so that water leaking problems occurring in operation vibration disturbing environments, such as underground passages and subway stations, can be effectively solved.
Owner:南京康泰建筑灌浆科技有限公司
Health tea for controlling body weight, reducing uric acid and reducing hypertension, hyperglycemia and hyperlipemia
The invention discloses health tea for controlling body weight, reducing uric acid and reducing hypertension, hyperglycemia and hyperlipemia. The health tea is prepared from the following raw materials in parts by weight: 10-20 parts of hawthorns, 5-10 parts of cassia seeds, 3-6 parts of sophora flower buds, 3-6 parts of fruits of Chinese wolfberry, 4-8 parts of polygonatum kingianum, 6-12 parts of roots of kudzu vine, 2-4 parts of wild jujube seeds, 6-12 parts of Chinese yams, 2-4 parts of smoked plums and 2-4 parts of radix glycyrrhizae. The invention further discloses a preparation method for the health tea for controlling body weight, reducing uric acid and reducing hypertension, hyperglycemia and hyperlipemia, wherein the preparation method comprises the following steps: cleaning hawthorns, cassia seeds, sophora flower buds, fruits of Chinese wolfberry, polygonatum kingianum, roots of kudzu vine, wild jujube seeds, Chinese yams, smoked plums and radix glycyrrhizae, drying, processing, crushing, pelletizing, drying and filling to obtain the health tea for controlling body weight, reducing uric acid and reducing hypertension, hyperglycemia and hyperlipemia. The invention also discloses application of the health tea for controlling body weight, reducing uric acid and reducing hypertension, hyperglycemia and hyperlipemia disclosed by the invention to preparing medicaments for treating diabetes, obesity, overweight and hyperuricemia, reducing blood pressure, blood sugar and blood fat.
Owner:韩超央
Solid beverage containing Radix Puerariae
InactiveCN103385520AImprove splanchnic circulationIncrease tissue oxygen supplyFood preparationDecompositionLiver metabolism
The invention discloses a solid beverage containing Radix Puerariae. The solid beverage is prepared by using 50-80 parts by weight of a Radix Puerariae extract, 30-50 parts by weight of dark plum, 5-10 parts by weight of soya lecithin, 5-10 parts by weight of Chinese magnoliavine and 5-10 parts by weight of turmeric. The solid beverage solves the problem of the single efficacy of anti-alcoholic products, is prepared through using the essences of purely natural green plants, and can accelerate the liver metabolism, reduce the liver loss, improve the liver immunity and promote the absorption and decomposition of alcohol.
Owner:张灵芝
Hyperglycemia-hyperlipidemia-hypertension relieving health protection tea and preparation method thereof
InactiveCN103349121AIncrease vitalityRepair functionTea substituesAcute hyperglycaemiaAdditive ingredient
The invention relates to hyperglycemia-hyperlipidemia-hypertension relieving health protection tea, and aims to solve the problems that the similar health care products are not obvious in hyperglycemia-hyperlipidemia-hypertension relieving effect and are scarce in raw materials. The hyperglycemia-hyperlipidemia-hypertension relieving health protection tea is prepared through the following steps: adding hawthorn fruits and wolfberry fruits into water, soaking for 10-20 minutes, heating and boiling for 5-10 minutes, and filtering to obtain filtrate; then adding coix seeds and licorice roots into the filtrate, soaking for 10-20 minutes, filtering and drying; finally, mixing the dried mixture with frosted folium mori and dicranostigma leptopodum, and grinding to obtain the hyperglycemia-hyperlipidemia-hypertension relieving health protection tea. The hyperglycemia-hyperlipidemia-hypertension relieving health protection tea is composed by taking traditional Chinese medicine theory as the bases; the components contained in the tea such as flavonoids, phenols, vitamins, carotenes, amino acids, mineral substances and organic acids can balance all nutritional ingredients for the human body; synthetic pharmacodynamic effects of all traditional Chinese medicines can be fully utilized to control or intervene hyperglycemia, hyperlipidemia and hypertension; therefore, the hyperglycemia-hyperlipidemia-hypertension relieving health protection tea has the efficacies of enhancing the body vigor, nursing the health, nourishing the vitality, recovering the langerhans gland function, relieving hyperglycemia, hyperlipidemia and hypertension, and diminishing the inflammation.
Owner:吴星剑
Soft skin-friendly superfine essence facial mask
InactiveCN106344490AGood skin feelPromote absorptionCosmetic preparationsToilet preparationsFiberCross-link
The invention discloses a soft skin-friendly superfine essence facial mask which comprises a superfine fiber facial mask cloth piece and soft skin-friendly superfine essence, wherein the superfine fiber facial mask cloth piece is used for carrying the essence; the soft skin-friendly superfine essence comprises allantoin, methylparaben, EDTA-2NA, glycerol, 1,3-propylene glycol, a crylic acid (ester) / C10-30 alkanol acrylic ester cross-linked polymer, 1.2-hexanediol, 1.2-pentanediol, polyglutamic acid, sodium hyaluronate, sodium hydroxide, a microemulsion preparation, PPG-24-polyether triols-24, trehalose, nicotinamide, saccharide isomeride / citric acid / sodium citrate, dipotassium glycyrrhizinate, phenoxyethanol, essence, a milk extract and a goat milk extract. The essence containing the microemulsion preparation and other skin softening components infiltrates in millions of superfine fiber micro-pores, and is coagulated to form 'milk skin' rich in nutrients, the facial mask is smooth and glutinous and soft and moist extremely, micro conduction osmotic pressure can be formed when skin is wrapped by the facial mask, then the nutrients can be deeply conducted into skin, the skin can have soft, moist and tender transparent gloss, and the facial mask is very good in skin feeling when being used.
Owner:NOX BELLCOW COSMETICS CO LTD
Organic biology feed premix material additive for breeding green livestock and poultry
InactiveCN101356953AWide range of raw materialsReduce manufacturing costFood processingAnimal feeding stuffFeed conversion ratioDomestic animal
The invention relates to a feed premix additive, in particular to an organic biological premix additive for the environment-friendly domestic animal raising. The premix additive is formed by the combination of Chinese herbal medicine concentrated solution, aloe versa powders and organic biological compound acid; wherein, the Chinese herbal medicine concentrated solution accounts for 20 to 70 percent of the total weight of the additive, the aloe versa powders accounts for 10 to 40 percent, and the organic biological compound acid, 20 to 60 percent. The additive is wide in raw material and low in production cost, and causes no pollution during production. Not only the utilization ratio of the feed is improved during feeding the domestic animals, the feed conversion ratio is superior to thatof other products and raisers can reduce the cost input of the animal feed, but also the fed live pigs and the products of eggs and chicken can reach the standards of green foods. The feed premix additive is a real green organic product that satisfies the health requirements of people.
Owner:民亨康健科技(北京)有限公司
Hair composition containing marine bio-active substance
ActiveCN108324591AReduce flakingRelieve inflammationCosmetic preparationsHair cosmeticsCuticlePiroctone olamine
The invention discloses a hair composition containing a marine bio-active substance. Specifically, the hair composition consists of D-glucosamine hydrochloride, marine shellfish peptide, fish proteinpeptide, algal polysaccharides and piroctone olamine, and furthermore, the hair composition can be assisted by olive oil and panthenol. The hair composition provided by the invention can serve as a hair shampoo, such as an anti-dandruff shampoo, having a special dandruff removal function; and after the use of the hair composition, a scalp cuticle structure and a normal barrier function can be repaired. The hair composition has multiple functions such as taking a lasting moisturizing effect, balancing oil secretion, inhibiting bacteria, diminishing inflammation, removing dandruff, relieving itching and the like; and in addition, the hair composition can also obviously improve hair quality, reduce furcation and relieve alopecia, and the hair composition can simultaneously conduct dandruff removing and hair nourishing.
Owner:FOSHAN ANAN BEAUTY & HEALTH PRODS +2
Synbiotic composition as well as preparation and application thereof
InactiveCN108378370AIncrease the number ofLong validity periodOrganic active ingredientsDigestive systemAdditive ingredientAntibiotic Y
The invention discloses a synbiotic composition as well as a preparation and application thereof. The synbiotic composition comprises prebiotics and probiotics in the weight ratio of the prebiotics tothe probiotics being (1-10) to (1-10). The synbiotic composition can exert the physiological and pathological bacterial activity of the probiotics, and through cooperation with the prebiotics, can selectively and quickly increase the quantity of the probiotics, so that the action speed of the probiotics is high, the effect is durable, and the physiological function of the probiotics and the prebiotics can be exerted at the same time. The synbiotic composition can effectively promote the repair of damage caused by antibiotics and damage caused by chemotherapy, and can particularly promote therepair of damage for a digestive system. Through scientific selection of combination of the probiotics and the prebiotics, and through an appropriate compounding ratio of the components, the synbioticcomposition is clear and notable in efficacy, the components are safe and effective, and the raw materials are reasonable in collocation. The synbiotic composition disclosed by the invention also hasthe advantages of being notable in effects, taking effect quickly, and being high in safety.
Owner:云南中京国建投资有限公司
In-situ-forming self-repairing antibacterial hydrogel and preparation method thereof
The invention relates to in-situ-forming self-repairing antibacterial hydrogel and a preparation method thereof. The medical hydrogel dressing with functions of fast in-situ forming, self-repairing and bacterium resisting is prepared by combining oxidized formyl sodium hyaluronate of different molecular weights and sodium hyaluronate of different molecular weights. Formyl has reaction with amino in polycation polymer to form dynamic Schiff base bonds which allows the hydrogel to have the self-repairing function, and free sodium hyaluronate of different molecular weights plays a synergistic role to promote skin repairing. The hydrogel is simple and convenient in preparation method, capable of achieving injection in-situ forming and promising in application prospect in the field of biological medical materials.
Owner:SHANDONG BRANDEN MEDICAL DEVICE
Ordered collagen scaffold and applications of ordered collagen scaffold in preparation of spinal cord injury repair products
ActiveCN109010915APromote growthPromotes spinal nerve regenerationTissue regenerationLiposomal deliveryNeural stem cellMicrotubule cytoskeleton
The present invention discloses an ordered collagen scaffold and applications of the ordered collagen scaffold in preparation of spinal cord injury repair products, wherein the ordered collagen scaffold comprises an ordered collagen sponge cylinder scaffold, the ordered collagen sponge cylinder scaffold comprises a three-dimensional structure formed mainly by orderly arranging a plurality of porechannel structures, the ordered collagen sponge cylinder scaffold is doped with liposome, and the liposome encapsulates an anticancer drug having microtubule stabilizing effect. According to the present invention, the ordered collagen scaffold has the ordered pore channel structure so as to provide the contact induction effect for neurite growth; and importantly the sustained release of the anticancer drug having microtubule stabilizing effect in the liposome can alleviate the influence of myelin protein in the environment after the spinal cord injury so as to promote the differentiation of the transplanted neural stem cells into the neurons and promote the growth of the neurite, such that the regeneration of the injured spinal nerves and the repair of the motor function can be promoted.
Owner:DUBU BIOSCIENCES
Skin-care makeup remover cream with skin surface lipid film repairing function and preparation method of skin-care makeup remover cream
InactiveCN105687038AEasy to cleanGood skin feelCosmetic preparationsMake-upLipid filmNatural barrier
The invention provides skin-care makeup remover cream with a skin surface lipid film repairing function. The skin-care makeup remover cream is prepared from components of raw materials in percentage by weight as follows: 20%-55% of grease, 10%-30% of an emulsifier, 2%-10% of polyethylene, 1%-25% of polyalcohol and / or deionized water, 5%-15% of squalane, 2%-5% of a traditional Chinese medicine additive and 0.1%-0.2% of methylparaben or phenoxyethanol or imidazolidinyl urea, and the sum of percentages of all the components is 100%. The skin-care makeup remover cream is a water-containing system, has good skin feeling, is not sticky, is very refreshing and has a good cleaning effect on water-soluble dirt while compared with a whole-oil system, people don't feel tight in face after using the cream, and skin is protected. The product has a low melting point, is solid-state paste at the normal temperature and can rapidly form thin oil after a little cream is slightly applied to the skin and spread on the skin; besides, through matched use of squalane and the traditional Chinese medicine additive, the skin-care makeup remover cream can repair a skin surface lipid film, form a natural barrier on the skin surface, promote proliferation of skin basal cells and help repair damaged cells.
Owner:CANTON DAMEKISS DAILY CHEM FACTORY LIMITED
Nutrient powder capable of improving children's immunity and preparation method of nutrient powder
InactiveCN105725201AImprove stress abilityEfficient SupplementFood preservationFood shapingAnti stressDisease
The invention relates to a nutritional powder for improving children's immunity and a preparation method thereof, belonging to the technical field of health food. The nutritional powder for improving children's immunity is characterized in that it is made of the following raw materials in parts by weight: 10-20 parts of quinoa flour, 30-50 parts of oat flour, and 30-45 parts of wheat flour. The nutritional powder for improving children's immunity of the present invention is rich in lysine, calcium, magnesium, phosphorus, potassium, iron, zinc, selenium, manganese, copper and other minerals that are lacking in plants, and is also rich in unsaturated fatty acids , flavonoids, B vitamins and vitamin E, choline, betaine, folic acid, α-linolenic acid, β-glucan and other beneficial compounds, as well as rich dietary fiber and anthocyanins, can effectively supplement nutrition , Enhance body function, restore physique, regulate immunity and endocrine, improve body stress ability, prevent disease, very suitable for children to eat regularly.
Owner:陈键
Composition with soothing and repairing effects and application thereof
InactiveCN111821211AHas soothing and restorative propertiesDelay water lossCosmetic preparationsToilet preparationsBenzoic acidIrritation
The invention discloses a composition with soothing and repairing effect. The composition comprises the following components in parts by weight: 1-10 parts of humectants, 0.5-5 parts of panthenol, 0.05-0.5 part of glycyrrhetic acid, 0.01-0.3 part of copper tripeptide-1, 0.01-0.2 part of carboxymethyl dextran and 0.005-0.2 part of dihydrooatoyl-o-aminobenzoic acid. The composition of the inventioncan soothe skin allergic reactions, improve skin tolerance, reduce degrees of irritation-caused reactions of skin to reddening, tingling, itching, etc., repair skin imbalance, skin barrier function and other problems caused by skin allergy, reduce skin moisture loss and promote skin recovery to a healthy state.
Owner:泉后(广州)生物科技研究院有限公司
Recombinant adeno-associated virus for efficient tissue-specific expression of RS1 protein and application
PendingCN113322281ASmall doseGood treatment effectSenses disorderPeptide/protein ingredientsGene deliveryWild type
The invention discloses a recombinant adeno-associated virus for efficient tissue-specific expression of RS1 protein and application. An RS1 protein expression cassette consists of a promoter-a target gene sequence-polyA, wherein the promoter is selected from an RK promoter, a target gene is selected from a wild-type RS1 gene or the codon-optimized RS1 gene, and the polyA is selected from any vector of rBG or bGH, and contains the RS1 protein expression cassette. According to the invention, a gene expression cassette is optimized, and the recombinant adeno-associated virus is used as a gene delivery vector, so that tissue-specific efficient and continuous expression of the RS1 protein is realized in retina or ganglion cells, thereby achieving the purpose of treating X-linked juvenile retinoschisis. Through tissue-specific expression of the target gene, the use amount of a virus vector can be reduced, and then the immune risk is reduced, and the purpose of long-acting treatment is achieved.
Owner:成都金唯科生物科技有限公司
Chenopodium quinoa willd potato chips and preparation method thereof
InactiveCN105410779AColor, fragrance and taste are improvedStay brittleFood ingredient functionsFood additiveChipped potatoes
The present invention belongs to the technical field of potato chip food, and particularly relates to a preparation method for Chenopodium quinoa willd potato chips. Object of the present invention is to solve the problems that the existing compound processed potato chips are single in nutritional value and relatively high in market price, contains a variety of chemical component food additives, and are easy to be broken. A technical scheme adopted in the present invention is that: the Chenopodium quinoa willd potato chips comprises the following raw materials in parts by weight: 70-100 parts of potato flour, 20-30 parts of Chenopodium quinoa willd flour, 10-15 parts of corn flour, 1-3 parts of table salt, 1-2 parts of seed powder of Chinese prickly ash, 1-2 parts of tea polyphenols and 0.21-0.3 part of baking soda. Advantages of the Chenopodium quinoa willd potato chips are that the Chenopodium quinoa willd potato chips are good in mouthfeel, rich in nutrition and not easy to be broken.
Owner:XINZHOU TEACHERS UNIV
Dihydro isoquinoline compound and application thereof in preparation of nerve protection or antidepressant medicament
InactiveCN104151242ALow toxicityProtective functionOrganic active ingredientsNervous disorderNeurotrophic factorsNerve cells
The invention belongs to the field of medicines and relates to a dihydro isoquinoline compound and application thereof in treatment of mental disorder, related to emotion, especially depressive disorder. Shown in a structural formula I, the dihydro isoquinoline compound has good protection activity on PC12 cells damaged under the induction action of corticosterone in an in vitro experiment, which suggests that the dihydro isoquinoline compound has a function of protecting nerve cells, further experiments verify that the dihydro isoquinoline compound can effectively improve level of BNDF (brain-derived neurotrophic factor) in nerve cells, the oxidation resistance of the nerve cells can also be effectively enhanced, and growth of the nerve cells is promoted; the dihydro isoquinoline compound has potential of treating mental disorder owning to repairing and protective effect on the nerve cells, is preferable for treating emotion and cognitive mental disorders, such as depressive disorder, senile dementia, anxiety, obsession and schizophrenia and is especially preferable for treatment of depression. In vivo experiments, including forced swimming and open field experiment, the dihydro isoquinoline compound shows obvious effect of alleviating depressive state of experimental animals respectively. The formula (I) is described in the specification.
Owner:SICHUAN UNIV
Medicine for treating adiposis hepatica and its prepn. method
InactiveCN1947787APromote generationRepair functionDigestive systemPlant ingredientsFatty liverHepatica
A Chinese medicine for preventing and treating fatty liver is prepared from 17 Chinese-medicinal materials. Its preparing process is also disclosed.
Owner:上海裕信生物制药有限公司
Dihydroisoquinoline compounds and their use in the preparation of neuroprotective or antidepressant drugs
InactiveCN104151242BLow toxicityProtective functionOrganic active ingredientsNervous disorderDiseaseNerve cells
The invention belongs to the field of medicines and relates to a dihydro isoquinoline compound and application thereof in treatment of mental disorder, related to emotion, especially depressive disorder. Shown in a structural formula I, the dihydro isoquinoline compound has good protection activity on PC12 cells damaged under the induction action of corticosterone in an in vitro experiment, which suggests that the dihydro isoquinoline compound has a function of protecting nerve cells, further experiments verify that the dihydro isoquinoline compound can effectively improve level of BNDF (brain-derived neurotrophic factor) in nerve cells, the oxidation resistance of the nerve cells can also be effectively enhanced, and growth of the nerve cells is promoted; the dihydro isoquinoline compound has potential of treating mental disorder owning to repairing and protective effect on the nerve cells, is preferable for treating emotion and cognitive mental disorders, such as depressive disorder, senile dementia, anxiety, obsession and schizophrenia and is especially preferable for treatment of depression. In vivo experiments, including forced swimming and open field experiment, the dihydro isoquinoline compound shows obvious effect of alleviating depressive state of experimental animals respectively. The formula (I) is described in the specification.
Owner:SICHUAN UNIV
Application of bioactive polypeptide PACAP in preparation of drugs for improving fertility of obese men
ActiveCN111110830APrevent and alleviate fertility impairmentElucidate protectionPeptide/protein ingredientsSexual disorderDiseaseEmbryo
The invention discloses an application of bioactive polypeptide PACAP in preparation of drugs for improving fertility of obese men, and belongs to the field of damaged fertility diseases of the obesemen. The bioactive polypeptide PACAP drugs provided by the invention can significantly prevent and relieve obesity-induced male fertility damage (mainly by improving blood lipid and sex hormone levels, reducing a testicular tissue oxidative stress level, improving obesity-induced testicular spermatogenic cell damage, inhibiting high lipid-induced apoptosis of spermatogonia GC-1, and improving sperm function and early embryo quality after in-vitro fertilization), and repair pathological change and reproductive system function of fertility damage of the obese men, the relationship between obesity and male infertility can be initially understood, the protective effect of the PACAP on obesity-induced male reproductive damage can be clarified, and a theoretical basis, an experimental basis anda targeted treatment strategy are provided for clinical diagnosis and treatment of obese male infertility.
Owner:JINAN UNIVERSITY
Cannabidiol-contained composition for treating face neuritis and preparation method of cannabidiol-contained composition
PendingCN110433278ARepair damageIncrease nutrient supplyNervous disorderHydrolysed protein ingredientsSide effectMicrosphere
The invention relates to a cannabidiol-contained composition for treating face neuritis and a preparation method of the cannabidiol-contained composition, and belongs to the technical field of medicalcompositions. In order to solve the problems that an existing face neuritis treatment method takes effect slowly and is large in side effects, the invention provides the cannabidiol-contained composition for treating face neuritis. The cannabidiol-contained composition for treating face neuritis is prepared through the steps of with cannabidiol, safflower total flavonoids, radix astragali total saponins and cornu cervi pantotrichum polypeptide as main effective components, firstly loading the main effective components on composite microspheres formed from chitosan and sodium alginate, and uniformly dispersing the medicine-loading composite microspheres in hydrogel formed from hyaluronic acid-dopamine under the action of rhamnolipid and poly gamma-glutamic acid, so as to obtain a gel composition. The composition disclosed by the invention is high in medicine loading quantity, high in biocompatibility, free from toxicity and free from stimulation to skin; and after the composition is applied to the face of a patient, effective medicine components directly permeate into damage nerves at skin bottom, microcirculation is quickly improved, the damaged nerves are repaired, neurotizationis promoted, and the functions of facial muscle are restored.
Owner:李卫
Natural plant growth stimulant and preparation method thereof
InactiveCN102067888AImprove physiological activityImprove developmentPlant growth regulatorsBiocideDiseaseStimulant
The invention discloses natural plant growth stimulant. The natural plant growth stimulant is characterized by being prepared from 50 to 54 weight parts of aqueous solution of chitosan at the concentration of 20 to 25 percent, 25 to 30 weight parts of bamboo juice, 5 to 10 weight parts of purified water, 5 to 10 weight parts of aqueous solution of propyl cellulose at the concentration of 2 to 5 percent, 1 to 2 weight parts of lecithin, 1 to 2 weight parts of lysozyme, 1 to 2 weight parts of humic acid and 1 to 2 weight parts of salicylic acid. The natural plant growth stimulant can improve the disease and insect resistance of crops, and regulate the physiological function of the crops so as to improve crop yield, and is safe and nuisanceless.
Owner:张益 +1
Compound fructus cannabis capsules, preparation method and applications thereof
InactiveCN105287943AOvercome limitationsEnhance memoryNervous disorderCapsule deliveryDiseaseBiotechnology
The present invention discloses compound fructus cannabis capsules and a preparation method thereof, wherein the compound fructus cannabis capsules are mainly prepared from the following raw materials by weight: 500-1000 parts of fructus cannabis, 500-1000 parts of marine microalgae, 500-1000 parts of ganoderma lucidum, 250-500 parts of camellia nitidissima leaf, 100-200 parts of camellia nitidissima flower, 25-50 parts of camellia nitidissima seeds, 500-1000 parts of black grape, 50-100 parts of walnut meat, 50-100 parts of Chinese Wolfberry, and 500-1000 parts of red date. According to the present invention, the compound fructus cannabis capsules have characteristics of fine formula selection and essence concentration, have effects of significant memory improvement and the like, are main used for preventing and treating hypomnesis, dysmnesia and Alzheimer disease, can further be used for preventing and treating Parkinson's disease, cardiovascular and cerebrovascular diseases, and malignant tumors caused by cerebrovascular diseases, anti-aging, and the like, and can further be used for memory enhancing, learning ability enhancing, intelligence enhancing and body constitution enhancing of teenagers or healthy people.
Owner:广西南宁隆吉维特生物科技有限公司
Nutritive bowl for field planting of leymus chinensis in deteriorated grassland
PendingCN109526469AImprove colonizationIncrease success rateGrowth substratesCulture mediaAqueous solutionLeymus
The invention discloses a nutritive bowl for field planting of leymus chinensis in deteriorated grassland. The nutritive bowl comprises nutritive bowl soil, wherein a brassinosteroid aqueous solution,formulation complex fertilizer and pregelatinized starch as a soiling bonding and nutritive bowl setting substance are added in the nutritive bowl soil; the success rate of field planting and expanding propagation of the leymus chinensis can be effectively improved, centralized management at seedling stage is facilitated and the utilization rate of the seeds and the survival rate of seedlings areimproved; rapid planting of the leymus chinensis in the deteriorated grassland and functional reconstruction of an ecological system are promoted; sufficient nutrients of the nutritive bowl can meetthe demands of field planting and expanding propagation of the leymus chinensis; once a cultivated nutritive bowl is transplanted to the deteriorated grassland, a large grassy field can be quickly restored by means of the advantages of colonizing division and integration of the leymus chinensis; by adopting the pregelatinized starch as a bonding and setting substance, the nutritive bowl is not easy to loosen or disintegrate, and the seedling stage management, movement, transportation and transplanting are facilitated.
Owner:INST OF BOTANY CHINESE ACAD OF SCI
Whitening sunscreen skin care matrix and preparation method thereof, and cosmetic and preparation method thereof
PendingCN114632038AFree radical scavengingInhibitory activityCosmetic preparationsToilet preparationsTyrosinaseGentiana Lutea Root
The invention discloses a whitening, sunscreen and skin-care matrix and a preparation method thereof as well as a cosmetic and a preparation method thereof, and relates to the technical field of cosmetics. Comprising the following components in parts by mass: 5-10 parts of a morinda citrifolia extract, 5-10 parts of a butterflybush flower extract, 5-10 parts of a Chinese gentian root extract, 5-10 parts of a cherry plum bark extract and 1-5 parts of acetyl tyrosine. According to the whitening, sun-screening and skin-care matrix disclosed by the invention, the morinda citrifolia extract capable of absorbing ultraviolet rays, the butterflybush flower extract with functions of repairing keratinocytes and resisting inflammation, the gentiana algida root extract capable of inhibiting melanogenesis and resisting inflammation, the cherry plum bark extract rich in anthocyanin and acetyltyrosine for competing for tyrosinase are selected as effective components; the whitening sunscreen cream can achieve a synergistic interaction effect, can absorb ultraviolet rays, effectively scavenge free radicals, inhibit the activity of tyrosinase and inhibit the generation of melanin, and has good whitening and sunscreen functions.
Owner:广州丸美生物科技有限公司
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