6results about How to "Improve local microcirculation" patented technology

The present application belongs to the technical field of traditional Chinese medicine composition, and relates to a traditional Chinese medicine transdermal external preparation for treating vulvar hypopigmentation disease. The preparation is a paste prepared by mixing traditional Chinese medicine powder and horse oil. The traditional Chinese medicine powder is composed of the following raw materials by weight: Xuchangqing 10-12, Pugongying 10-15, Difusiduo 12-15, Tuzifuding 12-15, Baiji 10-15, Huzhang 9-12, Quansie 6-10, Diyu 10-12, Xuezhi 10-12, Danggui 6-10, Rushang 6-10, Miedu 6-10, Bingpian 1-3. The traditional Chinese medicine transdermal external preparation has definite and significant effects on vulvar hypopigmentation disease, especially in relieving intractable pruritus, promoting pigment recovery and improving skin sclerosis / atrophy. The traditional Chinese medicine transdermal external preparation has high safety, few adverse reactions and low recurrence rate.

The application belongs to the technical field of biotechnology, and particularly relates to a pharmaceutical composition containing exosomes and application thereof. The pharmaceutical composition containing exosomes comprises stem cell exosomes, recombinant IGFBP7 protein and baeckea fruitin B; the amino acid sequence of the recombinant IGFBP7 protein is shown as SEQ ID NO:1. Test results show that the combination of umbilical cord mesenchymal stem cell exosomes, baeckea fruitin B and recombinant IGFBP7 protein can stimulate hair follicle stem cells, prolong the initial stage of hair growth of hair follicles, and thus effectively improve the hair loss of patients.

The invention discloses a spermidine composition for inhibiting aging of hair follicle stem cells and promoting growth period entry and application, and relates to the technical field of biological medicine and functional skin care. The invention discloses a spermidine composition for inhibiting aging of hair follicle stem cells and promoting growth period entry. The skin care product is prepared from the following components in parts by mass: 0.5 to 3 parts of spermidine, 0.2 to 2 parts of an autophagy activator, 0.5 to 4 parts of an antioxidant, 0.1 to 2 parts of a mitochondrial function accelerant, 0.2 to 3 parts of a microcirculation accelerant, 1 to 6 parts of a skin penetration accelerant, 0.2 to 1 part of a preservative, 0.05 to 0.4 part of a pH regulator and 60 to 95 parts of a carrier matrix. The composition can effectively reduce the aging rate of hair follicle stem cells and remarkably improve the proliferation activity of the hair follicle stem cells, active oxygen free radicals around the hair follicle stem cells can be effectively removed by adding the antioxidant of a novel structure, damage of external stimulation to hair follicles is reduced, and a systematic cell protection and repair mechanism is formed.

The invention belongs to the technical field of traditional Chinese medicine nursing, and discloses a traditional Chinese medicine health-care comb and a preparation method thereof.The traditional Chinese medicine health-care comb is prepared through the steps that traditional Chinese medicine powder, nanmu sticky powder, a nanometer whisker reinforcing agent and composite antibacterial factors are subjected to dry mixing and then mixed with a traditional Chinese medicine extracting solution according to the mass ratio of 1: 1, and compression molding is conducted; the mass ratio of the traditional Chinese medicine powder to the nanmu sticky powder to the nano whisker reinforcing agent to the composite antibacterial factor is (65-70): (20-25): (5-8): (2-3); through a double-effect fusion mode of the medicine powder and the extracting solution, combination of physical massage and medicine effect permeation is achieved, compatibility of multiple medicinal materials is achieved, the traditional Chinese medicine theory and scalp care requirements are considered, and multiple health-care effects of nourishing blood and blacking hair, growing hair and preventing hair loss, promoting blood circulation to remove meridian obstruction and balancing the scalp environment are achieved; meanwhile, a nano whisker reinforcing agent and a composite antibacterial factor are also added, so that the problems that the traditional Chinese medicine health-care comb is easy to break and mildew and short in service life in life and use are solved.

The present application relates to the technical field of active peptide, and discloses a kind of polypeptide and its application in preventing and treating alopecia;The amino acid sequence of the polypeptide is Phe-Trp-Ala-Phe-Phe-His, obtained by alkaline protease hydrolysis Lechriurus, it is verified by experiment, the polypeptide has the promoting effect to frizzled class receptor 7 protein (frizzled class receptor 7), can promote the growth and development of HDPCs cell, improve its migration activity, and can activate Wnt / β-catenin signal pathway, and up-regulate the expression of β-catenin, C-myc, CyclinD1 and LEF1 and other downstream key proteins, while promoting the expression of Wnt10b, also can alleviate the decrease of protein expression amount caused by inhibitor DKK1 and FZ7-21, therefore the polypeptide can promote hair follicle cell proliferation by Wnt / β-catenin signal pathway, regulate hair growth cycle, improve local microcirculation and other various ways to play hair growth effect, can be used for preparing hair growth drug, also can be used for preparing the cosmetics that help preventing and treating alopecia.

The utility model relates to the technical field of old nursing turning-over technology discloses an old nursing turning-over device, including the turning-over board, base and support, the lower end fixedly arranged of turning-over board is equipped with the fixed ring, the outer side wall fixedly arranged of support is equipped with the round ruler board, the movable shaft rod is equipped with in the support, the movable shaft rod fixed connection the fixed ring, the outer end fixedly arranged of movable shaft rod is equipped with the indicating rod, the indicating rod is equipped with the fixed location magnetic post and passes through, the guide column fixed connection the indicating rod, the air -permeable cloth bag is installed with miniature vibration motor in, the utility model discloses through setting up the gasket, double -sided magic tape, air -permeable cloth bag and cold and hot physiotherapy gel pad, can realize hot and cold physiotherapy and massage simultaneously, relaxes the muscle of old people, improves local microcirculation, adjusts time and rotates the turning-over board, and the guide column moves along the limit rail, and the fixed location magnetic post is inserted into the corresponding magnetic hole fixed to the target angle, so that nursing staff can more directly master the turning-over angle, greatly improves the nursing efficiency.