The invention discloses a method for simulating soil slope instability induced by groundwater. The method is characterized by comprising the following steps: a, putting a physical model on a centrifugal machine; b, raising the height of an external water tank, opening a water outlet valve and a water inlet valve, carrying out water seepage into a soil layer according to the thickness of a saturated soil layer and completing the saturation process of a soil mass; c, closing the water inlet valve, reducing the height of the external water tank, improving the centrifugal acceleration to solidifyand disperse the internal pore water pressure of the physical model; d, after the solidification is finished, opening the water inlet valve, raising the height of the external water tank to the corresponding height according to the preset water level height of an internal water tank; obtaining different infiltration capacity of the water to the slope when the water in the internal water tank seepsinto the soil layer and stays at different heights, and observing the wetting front change and the slope deformation condition of the physical model. The method disclosed by the invention has the advantages that the height of the groundwater level can be accurately adjusted in real time and washing of water current to the slope body is prevented; in the whole test process, high operability, highreliability and good test effect are realized.