56 results about "Natural substance" patented technology

The embodiment of the invention relates to the technical field of electrolytes, and provides a preparation method of a hydrogel electrolyte, the hydrogel electrolyte and a zinc ion battery, and the preparation method comprises the following steps: preparing a chitosan aqueous solution with a first preset concentration; the preparation method comprises the following steps: adding a certain amount of genipin into a chitosan aqueous solution, so that the genipin and chitosan in the chitosan aqueous solution are crosslinked at a first preset temperature; coating the cross-linked slurry on a substrate of a preset material, and drying and demolding at a second preset temperature to obtain a hydrogel electrolyte dry film; and soaking the hydrogel electrolyte dry film in a liquid electrolyte with a second preset concentration to absorb the liquid until the liquid is saturated, thereby obtaining the hydrogel electrolyte. Chitosan and genipin used in the embodiment of the invention are natural substances and are non-toxic and harmless, so that the prepared hydrogel electrolyte belongs to an environment-friendly electrolyte material, the problem that a cross-linking agent in a traditional electrolyte material is relatively high in toxicity is effectively avoided, and the problem of side reaction caused by using water as an electrolyte solvent is also avoided.

The present invention provides a mutton preservative and its application, belongs to the technical field of preservatives, the mutton preservative comprises component A and component B, component A comprises the following raw materials by weight: 10 parts of clove extract, 2-8 parts of cinnamon extract, 2-5 parts of bay leaf extract, 1-1.5 parts of tea polyphenols, 0.5-1 parts of allicin and 0.8-1 parts of calcium chloride; component B comprises the following raw materials by weight: 10 parts of chitosan, 3-5 parts of sodium alginate and 0.5-1 parts of propolis. The mutton preservative of the present invention adopts all pure natural substances, the sodium alginate and chitosan in component B react with the calcium chloride in component A to form a gel film, the clove extract, cinnamon extract and bay leaf extract in component A can also promote the cross-linking film formation of sodium alginate, the formed gel film is smoother, the internal structure is more compact, the water evaporation is prevented, the oxygen is isolated, and the preservation effect of the mutton preservative is effectively improved.

According to the dry fish maw capable of inhibiting fat oxidation and the preparation method thereof, fresh air bladders are soaked in a lactic acid bacteria solution, then subjected to anti-oxidation treatment with a chlorogenic acid solution, soaked in alkali liquor and dried, and the dry fish maw capable of inhibiting fat oxidation is obtained. Lactobacillus treatment and chlorogenic acid anti-oxidation treatment are combined, alkali is used for neutralizing generated acidic substances, natural substances are used for treatment, harmful compounds are not introduced, and the eating risk is reduced. Moreover, the yellowness value can be effectively reduced, the increase of POV value and TBA value is inhibited, the rancidity and rancidity of the dried fish maw are reduced, and long-time storage is facilitated. The preparation process is green and safe, short in treatment time and suitable for industrial production of dried fish maw.

The invention provides a targeted egg yolk cholesterol removal device and method, the device comprises a heating device, an infrared sensor, a liquid taking rod and other key components, and the temperature, layering position detection and supernate collection in the liquid treatment process can be accurately controlled. The whole process flow comprises the following steps: firstly, diluting the egg yolk with a NaCl solution, treating with phospholipase and performing enzyme deactivation treatment; then, determining a layering position by using an infrared sensor, and collecting supernate to a lower stirring tank. And then adjusting the pH value, and adding beta-cyclodextrin for further reaction. And finally, transferring the precipitate to a lower stirring tank through a high-pressure air pump, mixing the precipitate with the supernate, and performing centrifugal treatment to obtain the yolk with the cholesterol content greatly reduced. The phospholipase and cyclodextrin adopted in the invention are natural substances, have no toxic or side effect, and are safe and reliable. In the process of removing cholesterol, harmful substances are not generated, and the method is environment-friendly; the provided equipment is high in function integration degree, the number, cost and energy consumption of the equipment are reduced, and material loss is reduced.

The invention relates to cream for repairing radiodermatitis and a preparation method of the cream, and belongs to the technical field of biomedical skin treatment. The cream consists of the following components in percentage by weight: 8% of glycerin monostearate, 6% of stearic acid, 5% of white vaseline, 4% of liquid wax, 1-2% of tea tree oil, 1-2% of eugenol, 1-2% of vitamin E, 3% of trehalose, 8% of polyethylene glycol (PEG-400), 10% of glycerol, 0.5% of methylparaben, 1% of triethanolamine and the balance of purified water. According to the cream disclosed by the invention, the natural traditional Chinese medicine component eugenol and the natural substance vitamin E are utilized to synergistically enhance the anti-oxidation and bacteriostatic effects, and the tea tree oil, the trehalose and other effective components are utilized to repair radiodermatitis from multiple aspects of anti-inflammation, bacteriostasis, antioxidation, promotion of skin barrier repair and the like. The cream is simple in component, good in treatment effect, high in safety and convenient to produce and process, and can be popularized and applied to treatment of radiodermatitis.

The invention provides a PBAT / PLA antioxidant composite film and a preparation method thereof. The PBAT / PLA antioxidant composite film comprises the following raw materials in percentage by mass: 55-85% of PBAT resin; 5-25% of PLA resin; 0.1-3% of an interface compatibilizer; and the balance of auxiliaries. According to the PBAT / PLA antioxidant composite film disclosed by the invention, the interfacial compatibilizer is added, and phenolic hydroxyl groups at two ends of curcumin are subjected to epoxy modification treatment by the interfacial compatibilizer, so that on one hand, the interfacial compatibilizer reacts with carboxyl groups at two ends of PBAT and PLA, and the compatibility of PBAT and PLA resin interfaces is improved; the mechanical property of the composite film can be greatly improved. On the other hand, the curcumin is a natural substance and has excellent oxidation resistance, and the compatibilizer modified by the curcumin acts on the PBAT / PLA phase interface, so that the oxidation resistance and the biodegradability of the composite film are effectively improved, and the service life of the composite film in a high-ultraviolet region is prolonged.

The present invention provides a novel integrated platform capable of verifying the production process, standardizing and evaluating complex natural products, thereby enabling "as an integral system" characterization of complex mixtures contained in products (based on or consisting of natural substances) with therapeutic and / or health care effects, the characterization of the metabonomics is not limited to a reductive chemical method aiming at a single marker, and qualitative and quantitative data and fingerprint characterization metabonomics of the mixture are integrated with physical and biophysical activity data, so that the characterization of the product is realized, which is the basis of the verification process of the production process; and the reproducibility of different batches of products in the aspects of efficacy and safety can be ensured. The analysis platform described herein can ensure that a complex natural product is a whole, and all quality and efficacy characteristics of the product are considered, thereby ensuring reproducibility of effect and safety through a multi-dimensional analysis method.

The present invention provides a novel integrated platform that enables the verification of manufacturing processes for complex natural products, as well as the standardization and evaluation of complex natural products. This platform allows for the "system-wide" characterization of complex mixtures contained in therapeutic and / or health-promoting products based on or composed of natural substances, without limiting the approach to reductionist chemical approaches targeting single markers. This is achieved through the integration of qualitative and quantitative fingerprint characterization data metabolomics and physical and biophysical activity data for the mixtures, thereby providing a product characterization that forms the basis for verifying manufacturing processes that can ensure the reproducibility of efficacy and safety across different batches of the product. The analytical platform described herein enables the assurance of a complex natural product as a whole, by considering all the characteristics of its quality and efficacy, through a multidimensional analytical approach, in order to ensure reproducibility regarding efficacy and safety.

The invention relates to methods for dyeing keratin-containing fibers, in particular human hair, using plant polyphenols at a pH value in the range of 1.0 to 6.9 and / or at a content of at least one salt selected from the alkali metal salts or the ammonium salts of a halide anion or a pseudohalide anion, and subsequent treatment with one or more silver salts, as well as agents and kits for carrying out these dyeing methods.

The present invention relates to a process for preparing perfume concrete and / or absolute which employs bringing particular, fresh, withered or dry, solid natural material(s) into contact with a first system of solvents comprising at least one “green” organic (poly)ol solvent. Another subject of the invention is the perfume concrete and the perfume absolute obtained by the preparation process, a composition comprising the concrete and / or the absolute, and the use of the “green” organic (poly)ol solvent to extract the concrete and / or the absolute with no chemical odour of solvent odour type.

The present invention provides a feed-grade natural colorant and its preparation method and application. The preparation method of the feed-grade natural colorant includes the step of mixing a lipase oil suspension with a natural pigment extract for enzymolysis; the lipase oil suspension is composed of lipase, water, Tween 60, monoglyceride and grease, wherein the mass content of lipase is 3-10%, and the mass contents of Tween 60, monoglyceride and grease are 30-40%, 20-30% and 10-20% respectively. After the natural pigment extract is enzymolyzed with the lipase oil suspension, the absorption of the natural pigment in the small intestine can be greatly increased, and its bioavailability can be improved, thereby being applied to feed to improve egg yolk yolk color, fish skin color, etc., and the raw materials of the product of the present invention are all natural substances, with advantages such as safety and no toxic side effects, and can completely replace the use of chemically synthesized pigments in animal feed.

The invention discloses a method for producing hydrogen peroxide by two-electron electrocatalytic water oxidation of calcium carbonate-based natural substances, which comprises the following steps: (1) preparation of an anode material: loading the calcium carbonate-based natural substances such as egg shell powder, calcite powder, clam shell powder, coral powder and the like on a substrate through a naphthol binder to serve as the anode material; and (2) carrying out a reaction for synthesizing hydrogen peroxide by electro-catalysis water oxidation: constructing an electro-catalysis environment and electrochemical double cells, separating a cathode and an anode by a nafion membrane only allowing protons to pass through, taking a graphite sheet as the cathode, and taking a mixed solution of potassium carbonate and potassium bicarbonate as an electrolyte. And carrying out electro-catalysis water oxidation reaction to obtain a high-concentration hydrogen peroxide solution. The method simultaneously meets the requirements of resource utilization of the calcium carbonate waste and production of high-concentration hydrogen peroxide, and has the advantages of environmental friendliness and certain economic value.

A highly efficient purification device for improving the activity in the extraction of natural substances, comprising a low-temperature grinding unit, a high-pressure extraction unit, a filter, and a storage vessel, wherein the low-temperature grinding unit serves for cryogenic grinding of the natural substances to make the natural substances finer and to effectively maintain the activity of the natural substances, wherein the high-pressure extraction unit is connected to the low-temperature grinding unit, the filter to the high-pressure extraction unit, and the storage vessel to the filter; wherein the low-temperature grinding unit comprises a main body, a liquid nitrogen supply structure, and a comminution structure, wherein a cooling chamber and a receiving chamber are provided in the main body, the cooling chamber is located above the receiving chamber, the cooling chamber opens upwards and forms a material inlet opening.the cooling chamber is laterally connected to a liquid nitrogen channel and the liquid nitrogen supply structure is continuously connected to the liquid nitrogen channel to supply the cooling chamber with liquid nitrogen and thereby rapidly cool the natural substances to a frozen state, wherein the main body has an elongated comminution chamber and a material outlet opening and the two ends of the comminution chamber are each continuously connected to the receiving chamber and the material outlet opening, wherein the comminution structure mainly consists of a motor and a screw conveyor driven by the motor, the screw conveyor is arranged at the lower edge of the receiving chamber and runs axially in the comminution chamber and spiral paddles are arranged on the outer circumference of the screw conveyor, whereby the natural substances are compressed and ground by the screw conveyor and the comminution chamber;wherein the high-pressure extraction unit comprises a high-pressure extraction vessel and a pressurization structure, wherein the high-pressure extraction vessel is connected to the pressurization structure, the high-pressure extraction vessel serves to receive the milled natural substances and the solvent, the pressurization structure serves to increase the internal pressure in the high-pressure extraction vessel and to improve the extraction rate of the natural substances, and the high-pressure extraction vessel has a material inlet opening connected to the low-temperature milling unit through which the milled natural substances are introduced into the high-pressure extraction vessel, wherein the high-pressure extraction vessel has a material outlet opening connected to the filter such that, in a high-pressure state, the solvent dissolves the active ingredients of the natural substances to form an extraction liquid,which is then forwarded to the filter; , the filter serves to filter the extraction liquid in order to remove the solid components from the extraction liquid; wherein the storage container is connected to the filter and serves as a container to receive the extraction fluid passing through the filter.

The invention discloses an in-situ rapid fragrance locking method after aromatic plant harvesting, and belongs to the technical field of natural plant processing. According to the method, after aromatic plant raw materials are harvested, the aromatic plant raw materials are subjected to low-temperature fidelity treatment in a field, a field edge, a planting base or a processing factory through or without the steps of spreading for airing, aging, air drying and pretreatment by adopting any one mode of low-temperature distillation, low-temperature extraction and adsorption fragrance trapping, and in-situ instant stabilization of the raw materials is achieved; the raw materials can be used independently or synchronously co-extracted with aromatic plants without chemical conflicts. The method can effectively reduce the component loss and oxidation of the raw materials in the transportation and storage process, retains the freshness, naturalness and integrity of natural substances, is mild in treatment condition and wide in application range, and can meet the requirements of field operation and large-scale production.

The application discloses a method for preparing total anthraquinones in rhubarb by ultrafiltration-serial countercurrent extraction, and belongs to the technical field of natural substance separation. The method comprises the following steps: extracting rhubarb raw materials by ammonia osmosis, removing macromolecular impurities from the obtained osmosis liquid by ceramic ultrafiltration membrane filtration; adjusting the pH of the ultrafiltrate to serve as an extracted water phase, and performing countercurrent extraction on the extracted water phase by an extractant composed of solvent No. 260 and tributyl phosphate or trialkyloxy phosphine; loading the extractant to perform countercurrent back extraction on the extractant by an alkaline back extraction agent; and finally, acidifying, concentrating and drying the back extraction liquid to obtain high-purity total anthraquinones in rhubarb. The application couples ultrafiltration, serial countercurrent extraction and complexation extraction, solves the defects of traditional processes, such as easy emulsification, great solvent toxicity, high residue and high cost, and has the advantages of high selectivity of target components, high product purity, recyclable extractant, green and environment-friendly process, suitability for industrial production and the like.

This invention discloses a pH colorimetric membrane for indicating meat freshness, obtained through the following steps: First, konjac glucomannan and polyvinyl alcohol are dissolved separately in distilled water and heated and stirred until dissolved; then, the konjac glucomannan aqueous solution and the polyvinyl alcohol aqueous solution are mixed to obtain a film-forming solution; curcumin and alizarin are added to the film-forming solution, homogenized using a homogenizer, and then ultrasonically treated to remove air bubbles; the solution is poured into a plastic petri dish and dried in an incubator to obtain the pH colorimetric membrane. This invention uses a 3:1 mass ratio of curcumin and alizarin as colorants, resulting in stronger pH sensitivity and more obvious color changes. Furthermore, all raw materials used are derived from natural substances, are safe and non-toxic, and edible. No complex processing of meat samples is required, making the operation simple and low-cost. It has great application potential in meat freshness monitoring and intelligent packaging, and can be applied to the freshness monitoring of various meat products.

The invention relates to the technical field of cosmetics, in particular to vegetable dye pigment and hair dye based on an alcohol-water system and an application method of the vegetable dye pigment and hair dye. The pigment comprises a vegetable dye extract; the raw materials of the plant dye extract comprise at least one of madder, pomegranate rind and rheum officinale. Compared with a traditional chemical synthetic hair dye, the hair dye completely adopts natural plant pigments, food-grade mordants, natural substances such as tannic acid, pH regulators and the like, does not contain aniline cancerogens, greatly reduces the allergy risk and irritation to scalp, and is safe to human bodies.

The application provides a moisture-proof and water-resistant translucent paper and a preparation method and application thereof, and relates to the field of paper processing. The moisture-proof and water-resistant translucent paper comprises a translucent base paper and a first water-proof layer and a second water-proof layer formed on the surface of the translucent base paper in sequence. The coating material for forming the first water-proof layer comprises the following raw materials in parts by weight: modified starch 0.5-5.0 parts, sodium alginate 0.5-5.0 parts, chitosan 0.5-5.0 parts, nano-cellulose 0.5-5.0 parts, polyvinyl alcohol 0.5-5.0 parts and water 100 parts. The coating material for forming the second water-proof layer comprises the following raw materials in parts by weight: ethyl cellulose 0.5-5.0 parts and alcohol 100 parts. The raw materials are all degradable substances, which replace the film coating and internal sizing from the source, and solve the problem of waste paper recycling difficulty. The raw materials are all modified products of natural substances, and are high in safety. The double-layer coating structure greatly improves the moisture-proof and water-resistant performance of the translucent paper.

The application provides a kind of microbial nutrient carrier based on porous chemical material and its preparation method, belongs to sludge treatment technical field.The preparation method includes (1) after mixing glucose, fish meal, yeast powder uniformly, nutrient substance mixed powder is obtained, and after mixing with natural substance again, nutrient substance is obtained;(2) microbial bacteria liquid and nutrient substance mixed powder are fully stirred uniformly, mixture is obtained, then mixed with porous carrier, and after being fully oscillated, the microbial nutrient carrier is obtained after drying and solidification.The carrier has high porosity, good mechanical strength and excellent strain loading capacity, when applied to sludge aerobic fermentation, can quickly start fermentation, significantly improve organic matter degradation efficiency and strengthen dewatering effect, has good industrial application prospect.

The invention relates to the technical field of natural substance modification, and particularly discloses glutamic acid modified hydroxypropylated tremella powder as well as a preparation method and application thereof. The preparation method comprises the following steps: firstly, improving the solubility and dispersity of tremella powder through a hydroxypropylation reaction; preparing a reaction intermediate from glutamic acid and ethylene glycol diglycidyl ether; finally, grafting of glutamic acid on the hydroxypropylated tremella powder is achieved through an etherification reaction. After the tremella powder is subjected to the modification process, the performance improvement is obviously superior to the effect of tremella polysaccharide modified by the same process, the oxidation resistance, aging resistance, antibacterial property and moisturizing property of the modified tremella powder are obviously improved, and the modified tremella powder has wide application value in multiple fields of oxidation resistance, aging resistance, antibacterial property, moisturizing property and the like; the tremella fuciformis powder can be used for developing functional cosmetics, health food and medical products, and a new technical approach is provided for high-value utilization of the cheap tremella fuciformis powder.

The present invention relates to an oil-proofing agent that is in harmony with the environment and uses natural materials as biomass materials to impart sufficient oil resistance. In the oil-proofing agent of the present invention, the hydrogen atom of the hydroxyl group in the natural material having at least one hydroxyl group is substituted by an R group. The R group is a group represented by -Y-Z, wherein Y is a direct bond, -C(=O)-, -C(=O)-NR'- or -C(=S)-NR'-, wherein R' is a hydrogen atom or an alkyl group having C1 to C4 carbon atoms, and Z is a hydrocarbon group having 1 to 40 carbon atoms which may have a substituent, or a polysiloxane. The natural material is preferably a monosaccharide, a polysaccharide, glycerol or a polyglycerol.

The application discloses application of a polysaccharide of Ossyra edulis in preparation of an anti-plant virus agent. The polysaccharide is obtained by alkali extraction and alcohol precipitation of dry sclerotia of Ossyra edulis. The application finds that the polysaccharide of Ossyra edulis shows significant anti-virus activity on various plant pathogenic viruses in a pot experiment, and its preparation also shows good activity in a field efficacy test, and is significantly better than a positive control agent. Compared with the prior art, the application develops an anti-virus agent pesticide from a biological source of natural substances, has good environmental compatibility, safety, high efficiency, green environmental protection and the like, and has a wide application prospect.

The invention relates to a method for extracting and separating natural substances, in particular to a method for extracting reserpine from rauvolfia verticillate under the assistance of microwaves, which comprises the following steps: S10, an extraction step: crushing rauvolfia verticillate root bark, mixing with an acidic ethanol solution, and carrying out microwave extraction; s20, coarse crystallization: centrifuging the extracting solution, concentrating, performing acid precipitation, adding methanol for reflux, and standing to obtain a crude product; and S30, recrystallization: pulping the crude product with ethanol, recrystallizing with an acetone-ethanol system, and drying to obtain a finished product. The method disclosed by the invention is environment-friendly and high in extraction efficiency, the time of the extraction process is greatly shortened, and the use amount of a toxic organic solvent is reduced; meanwhile, ethanol is used for replacing an organic solvent in the process, so that the process is simple and convenient, the operation is simple, the toxicity is low, the safety is high, organic solvent recovery is facilitated, and the production cost is reduced.

The present invention relates to a dental disclosing composition and a screening method therefor, and more specifically, to a dental disclosing composition comprising cacao pigment or gardenia blue pigment, and a screening method therefor. Containing a natural material that has stable chemical properties, food-grade usability, and dyeability, the composition is ingestible and suitable as a substitute for conventional disclosing solutions. Moreover, the composition is expected to be widely applicable as a means for evaluating the effectiveness of dental disclosing materials.

The invention belongs to the technical field of natural substance extraction, and particularly relates to a method for extracting walnut shell total polyphenol by using a grinding ball-assisted deep eutectic solvent. The invention provides a method for extracting walnut shell total polyphenol by using a ball-milling-assisted deep eutectic solvent, and high-value utilization of walnut shell byproducts is realized. According to the main scheme, ball-milling assistance and a deep eutectic solvent are combined, and based on a ball-milling-assisted extraction technology, through the impact, extrusion and shearing effects of grinding balls, the plant cell wall structure can be effectively destroyed, permeation of the solvent into cells is accelerated, and dissolution of active ingredients is promoted; meanwhile, the used deep eutectic solvent has good biocompatibility and small destructive effect on total polyphenol active ingredients, the original physiological activity of the deep eutectic solvent can be well reserved, the synergistic interaction of mechanical wall breaking and green solvent dissolution is achieved, the substantive technical effect is achieved, the bottleneck problem of a traditional extraction method is solved, and the application prospect is wide.

Compared with an organic polyhydric alcohol type commercial cooling liquid (anti-freezing liquid), the biodegradable nanofluid heat exchange agent provided by the invention has remarkable technical characteristics. The invention relates to a special formula composition which is composed of six natural products, namely bentonite, hydroxypropyl starch serving as a dispersing agent, asparaginic acid serving as a corrosion inhibitor, chitosan serving as a defoaming agent, gelatin serving as a particle stabilizer and water. The preparation reaction depends on the hydration process of bentonite particles to provide power, and the spontaneous reaction is completed in one step. The heat exchange efficiency of the heat exchange agent can be improved by 32%, and biomass materials contained in the heat exchange agent can be automatically degraded in nature.

A mixing device combining protein carriers with natural substances, comprising: a mixed solution formed by mixing water and natural substances; a protein carrier consisting of genes that send the same signals as human cells and can therefore pass through the cell membrane and penetrate human tissue cells; a mixing container which has the shape of a hollow container and an upper wall, comprising a lower wall, two side walls and a receiving container, the receiving container holding the mixing solution and the protein carrier; a stirring device which is arranged in the receiving vessel of the mixing vessel and is further connected to a drive motor located outside the mixing vessel in order to drive the stirring device to stirring by the drive motor and To promote chelation of the mixed solution and protein carrier contained in the receiving container; a culture additive that is added to the receiving container of the mixing container, so that the natural substances are bound to the protein carrier to form complex nutrients; This allows the natural substances to penetrate human tissue cells via the protein carrier, ensuring the beneficial effects of complete nutrient retention and increased absorption rate.

The present invention discloses a photodynamic therapy gel composition for 3D printing and its preparation method. The gel composition comprises the following components: 0.1-10% by mass of a photosensitizer, 70-97.9% by mass of a temperature-sensitive gelling agent, 1-10% by mass of a coupling agent, and 1-10% by mass of an auxiliary agent. Compared with existing technologies, the present invention has the following advantages: the materials are primarily derived from natural substances, which are friendly to life and health; the preparation process is simple, with no resource waste or waste discharge, and the application environment is safe and controllable; and the temperature-sensitive hot melt characteristics are utilized for 3D printing, making it suitable for a variety of tissue and organ treatments.

The present invention relates to a composition for preventing or treating sleep disorders, the composition comprising a mixture of a Perilla frutescens extract and a Mentha piperita extract as an active ingredient. Specifically, the mixture, which is the active ingredient of the present invention, of a Perilla frutescens extract and a Mentha piperita extract improves sleep quality by reducing sleep latency and prolonging sleep duration in animal models, and thus can be effectively used as a composition for effectively improving sleep in which the composition is a natural substance with few side effects.

The present invention relates to: a composition for improving cognitive function, comprising a natural extract complex; and use thereof. According to an embodiment of the present invention, a composition for improving cognitive function or memory, comprising one or more selected from the group consisting of a Perilla frutescens var. acuta kudo extract, a Moringa oleifera extract, and a Phyllanthus emblica extract, exhibits few side effects due to being based on natural substances, is readily available, and provides an excellent cognitive function improvement effect while being cost-effective. Therefore, the composition can be effectively used for the prevention, amelioration or treatment of diseases associated with cognitive or memory impairment.