110 results about "Radiodermatitis" patented technology

The present invention relates to compositions and methods for the treatment of traumatic conditions of the skin including radiation dermatitis, thermal burn, sunburn, dermatomyo-fibromas, and exposure-induced wrinkles, comprising omega-3 fish oils, tocopherols, lavender oil and a suitable amount of a pharmaceutically acceptable carrier, and optionally, one or more of the following: Sodium PCA, or MSM.

An apparatus and a method for the therapy of a range of dermatological conditions using precisely formulated gaseous milieus featuring the beneficial functions of oxygen and ozone. A range of clinical applications for this system include the therapy of gas gangrene, infected wounds, poorly healing wounds, war wounds, decubitus ulcers, dermatological conditions due to circulatory disorders, lymphatic diseases of the skin, fungal skin infections, burns, nail afflictions, radiodermatitis, parasitic skin infestations, and frostbite.

A composition for the preventing, reducing or treating radiation dermatitis includes a mixture of one or more compounds that regulates cell differentiation and / or cell proliferation, and one or more antioxidants formulated in a pharmaceutically acceptable carrier. The composition of the present invention may further include a flavonoid. A method for the topical administration of the composition in accordance with the present invention for the purpose of preventing, reducing or treating radiation dermatitis involves topically administering an effective amount of the composition of the invention an area of skin which has been or will be exposed to radiation. The composition and method can be employed to prevent, reduce or treat radiation dermatitis caused by a wide variety of types of radiation exposure and is particularly useful for the prevention, reduction or treatment of radiation recall dermatitis.

The present invention relates to compositions comprising a proanthocyanidin, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but not limited to, atopic dermatitis(eczema), allergic contact dermatitis, seborrheic dermatitis, psoriasis, xerosis and atopia, as well as treatment of an inflammatory condition of mucosae and of an inflammatory condition in the eye. The present invention also relates to compositions comprising a proanthocyanidin, glycyrrhetinic acid and telmesteine, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but not limited to, atopic dermatitis, allergic contact dermatitis, seborrheic dermatitis, radiation dermatitis, psoriasis, xerosis and atopia, as well as treatment of an inflammatory condition of mucosae and of an inflammatory condition in the eye.

The invention discloses a polysaccharide combination, which is prepared by 0.01-10 percent of chitosan, 0.01-20 percent of oat beta-glucan and 70-99.98 percent of water. The polysaccharide combination is prepared through a method which comprises the following steps of: dissolving oat beta-glucan in the water to prepare oat beta-glucan dissolved water solution; and adding water into the chitosan for swelling, removing foams after one night to prepare chitosan gel, and mixing and evenly agitating the two kinds of solutions to finally obtain the polysaccharide combination which is prepared by using 0.01-10 percent of chitosan, 0.01-20 percent of oat beta-glucan and 70-99.98 percent of water. The polysaccharide combination can be used for the preparation of medical dressings, wound care agents, medicines for preventing and curing radiodermatitis, medicines for curing ulcers caused by bedsores and diabetes mellitus and dental ulcers, and medicines for promoting wound healing and reducing scars.

The invention aims to provide an application of glycyrrhizic acid, glycyrrhetinic acid or salt thereof in preparation of medicines for locally preventing and treating radiodermatitis so as to solve the problem of low effective rate of the conventional anti-radiodermatitis method, and further provides a preparation method for glycyrrhizic acid, glycyrrhetinic acid or salt and chitosan mixing composition according to the application. Compound biological gel prepared by the method has better therapeutic effect compared with that of the conventional anti-radiodermatitis medicine, has the radiodermatitis-preventing effect which the conventional medicine does not have, and is safe, non-toxic and non-irritant for a human body.

Provided herein are topical formulations containing copper ions and methods of treating radiation dermatitis, damage caused by radiation therapy, or other radiation-induced damage conditions in various areas of the body using such formulations. Methods of treating radiation dermatitis using topical copper ion treatments are provided. A topical treatment in its basic form comprises a biocompatible copper ion solution or suspension obtained by leaching of the copper ions from copper metal. The copper ion solution or suspension is combined with various carriers to form the copper ion treatment including creams, gels, lotions, foams, pastes, tampons, solutions, suppositories, body wipes, wound dressings, skin patches, and suture material. Methods of making the copper ion solution or suspension from solid copper metal in a biocompatible solution are also provided.

Described herein are emulsions and compositions for the treatment of various dermatoses. The emulsions may be formulated as aerosol compositions. The aerosol propellant may be a hydrofluoroalkane propellant. Also described are methods of treating dermatoses, comprising the step of applying to an affected area of a subject in need thereof a therapeutically-effective amount of an inventive emulsion or aerosol composition. The dermatosis may be atopic dermatitis, allergic contact dermatitis, or radiation dermatitis.

The invention relates to a Chinese patent medicine ointment for treating radiodermatitis. The ointment consists of Baikal skullcap root, coptis, phellodendron, red sage root, lithospermum, notoginseng, borneol, lanolin, ethyl nipagin ester, vaseline and the like, wherein (1) according to weight percentage, 20 to 25 percent of Baikal skullcap root, 20 to 25 percent of coptis, 20 to 25 percent of phellodendron, 15 to 18 percent of red sage root and 15 to 18 percent of lithospermum are mixed, so as to extract liquid medicine by a water decocting method, and the liquid medicine is heated to concentrate into dense extractum with relative density between 1.22 and 1.26 (measured at a temperature between 55 and 65 DEG C); and (2) according to weight percentage, 42 to 55 percent of the dense extractum, 35 to 48 percent of vaseline, 2.5 to 3 percent of lanolin, 2.5 to 3 percent of notoginseng powder, 2.5 to 3 percent of borneol and 2.5 to 5 percent of ethyl nipagin ester are evenly mixed, separately packaged and prepared into the ointment. The ointment is a traditional Chinese medicine product, has the advantages of good treatment efficacies, small toxic and side effects, low price, easy acceptance by patients, and easy popularization and application.

The present invention relates to compositions comprising a proanthocyanidin, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but not limited to, atopic dermatitis(eczema), allergic contact dermatitis, seborrheic dermatitis, psoriasis, xerosis and atopia, as well as treatment of an inflammatory condition of mucosae and of an inflammatory condition in the eye. The present invention also relates to compositions comprising a proanthocyanidin, glycyrrhetinic acid and telmesteine, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but not limited to, atopic dermatitis, allergic contact dermatitis, seborrheic dermatitis, radiation dermatitis, psoriasis, xerosis and atopia, as well as treatment of an inflammatory condition of mucosae and of an inflammatory condition in the eye.

Covalent Granzyme B inhibitors, compositions that include the compounds, and methods for using the compounds. A method for treating cutaneous scleroderma, epidermolysis bullosa, radiation dermatitis, alopecia areata, and discoid lupus erythematosus are provided.

Proline compounds as Granzyme B inhibitors, compositions that include the compounds, and methods for using the compounds. Methods for treating cutaneous scleroderma, epidermolysis bullosa, radiation dermatitis, alopecia areata, and discoid lupus erythematosus are provided.

Pyrrole compounds as Granzyme B inhibitors, compositions that include the compounds, and methods for using the compounds. Method for treating cutaneous scleroderma, epidermolysis bullosa, radiation dermatitis, alopecia areata, and discoid lupus erythematosus are provided.

The invention belongs to the technical field of medicines, and in particular relates to a medicine for radiodermatitis and a preparation method thereof. The medicine for radiodermatitis disclosed by the invention is prepared from the following traditional Chinese medicinal materials in parts by weight: 11-19 parts of fructus forsythiae, 6-14 parts of common andrographis herb, 11-19 parts of groundsel, 11-19 parts of radix sophorae flavescentis, 11-19 parts of bunge corydalis herb, 11-19 parts of herba chloranthi serrati, 11-19 parts of tobacco, 6-14 parts of duckweed, 6-14 parts of fructus cnidii, 6-14 parts of golden cypress, 11-19 parts of longtube ground ivy herb, 15-25 parts of the root of red-rooted salvia, 11-19 parts of the root bark of the peony tree, 11-19 parts of radix paeoniae rubra, 3-9 parts of leech, 20-40 parts of codonopsis pilosula, and 1-3 parts of menthol. The medicine disclosed by the invention has the better effect of preventing radiodermatitis; pain of patients suffered from radiotherapy is greatly relieved.

A composition is hereby described, comprising virgin oil of Cannabis sativa or a derivative thereof, hyaluronic acid, a salt or derivative thereof, and cosmetically or pharmaceutically acceptable excipients. Specifically, this composition has proved to be particularly suitable for the treatment of the skin both when affected by lesions, by intervening actively in the process of healing, and when subjected to treatment with radiations, by intervening actively in the prevention and reduction in the incidence of radio-dermatiti and dermatitis induced from the radiations.

A formulation for a stable ascorbic acid composition which, in a simplified form, is comprised of ascorbic acid in solution with a hygroscopic compound (i.e., a substance with the ability to attract water molecules from the surrounding environment through either absorption or adsorption). Also disclosed herein are methods for the production of such compounds and methods of using such compounds in the prevention, inhibition and treatment of striae gravidarum, radiation dermatitis, rhytids, lentigoes, dyschromia, sun-damage induced hyperpigmentation, cellulite, scars and purpura, among other skin diseases or conditions.

The present invention relates to compositions and methods for the treatment of traumatic conditions of the skin including radiation dermatitis, thermal burn, sunburn, dermatomyo-fibromas, and exposure-induced wrinkles, comprising omega-3 fish oils, tocopherols, lavender oil and a suitable amount of a pharmaceutically acceptable carrier, and optionally, one or more of the following: Sodium PCA, or MSM.

The invention relates to a traditional Chinese medicinal composition capable of preventing and treating radiodermatitis and a preparation method of the composition. The traditional Chinese medicinal composition is prepared from the following raw materials by weight: 15g of raw rheum officinale, 10g of coptis chinensis, 10g of Chinese angelica, 12g of raw sanguisorba officinalis, 15g of raw rehmannia, 10g of lithospermum, 10g of agrimonia pilosa ledeb, 10g of moutan bark, 10g of dictamni cortex, 10g of bistort rhizome, 10g of broom cypress fruit, and 5g of raw liquorice. The traditional Chinese medicinal composition capable of preventing and treating radiodermatitis is remarkable in curative, low in cost and comprehensive in action, does not have side effects, and can be used for treatment instead of hormones.

The invention discloses an external Chinese medicinal composition for treating II-III radiodermatitis. The external Chinese medicinal composition is characterized by comprising the following components in parts by weight: 15 parts of sinkiang arnebia root, 6 parts of indigo, 6 parts of coptis root, 15 parts of rheum rhaponticum, 12 parts of frankincense, 12 parts of myrrh and 500ml of sesame oil.The medicinal oil can be prepared by grinding all medicinal materials into coarse powder according to the weight ratio; soaking with the sesame oil heated to 70-80 percent for one week; and filteringand removing dreg. Various raw materials in the Chinese medicine are reasonably matched, are mutually coordinated and commonly play roles of removing pathogenic heat from blood, dissolving accumulated stasis of blood and detoxifying and arresting pain and promoting granulation. The external Chinese medicinal composition has the advantages of convenience of obtaining materials, low price, safety for use, favorable effect and the like, relieves the pains of patients and ensures the smooth operation of radiation treatment.

The invention relates to an ointment for treating radiodermatitis and a preparation method. Active ingredients of the ointment include the following raw materials: houttuynia cordata, centella, Japanese stephania root, Chinese blister beetle, Chinese juniper leaf, sophora alopecuroide, witch hazel, buchnera cruciata ham, blackberry lily, silk cotton, radices lithospermi, polygonum multiflorum, giant knot weed, honeycomb, tomatoes and catalpa leaf. The ointment is proper in compatibility of medicines and is consistent with traditional Chinese medicine and modern medicine study theory, and is prepared through a modern and advanced pharmaceutical technology; the ointment has functions of clearing away heat and toxic materials, diminishing inflammation and relieving pain, removing the necrotic tissue and promoting granulation, and is obvious in curative effect on radiodermatitis caused by radioactive factors, long on action duration, safe and free from toxic and side effects, short in treatment course and rapid to take effect; and the ointment can be widely applied to clinical treatment of radiodermatitis.

The invention relates to an externally applied skin tissue protection and repair preparation. The compound preparation includes the following components: (1) polyethylene glycol; (2) water; and (3) a flavonoid compound. The compound preparation can: (1) repair skin injury or promote wound healing; (2) eliminate scars; (3) prevent or treat radiotherapy caused skin damage; and (4) prevent or treat radiodermatitis.

The invention relates to pressure sore paste, a preparation method thereof and application thereof. The pressure sore paste comprises the following raw material medicines in part by weight: 80 to 120 parts of oriental buckthorn root, 80 to 120 parts of danshen root, 30 to 60 parts of dog oil and 15 to 20 parts of compound sulfamethoxazole tablets. The preparation method for the pressure sore paste is characterized by comprising the following steps of: (1) slicing the oriental buckthorn root and adding into water with the danshen root, and boiling to obtain liquid medicine; (2) filtering and drying the medicine dregs, grinding into fine powder and adding into the liquid medicine; and (3) adding the dog oil into the liquid medicine, stirring uniformly and boiling to obtain viscous liquid for preparing a medicament for treating pressure sore. The pressure sore paste and the preparation method have the advantages that: the pressure sore paste has functions of relieving pain, activating blood, dissolving stasis, eliminating necrosis and generating muscles, can effectively prevent and treat pressure sore, has obvious curative effect, good curative effect on radiodermatitis and can relieve the pain in patients and improve the living quality of the patients; moreover, a few kinds of raw materials, which are cheap and readily available, are used and the preparation method is simple and easy.

The invention relates to a composite containing borneol and alum. The composite can be prepared into an external traditional Chinese medicine preparation for diseases such as empyrosis, allergic skin diseases, surgical wound infection, chemical drug-induced phlebitis, radiodermatitis, and the like. Each 100 ml of emulsion of the composite nanometer emulsion containing borneol and alum comprises 0.125 g to 2.5 g of borneol, 0.69 g to 6.9 g of alum, 0.3 g to 3 g of oil for injection, 0.8 g to 8 g of emulsifier, 0.1 g to 1.5 g of sodium chloride and the balance of distilled water or water for injection, and the particle size range is from 1 to 100 nanometers.

The present disclosure relates to topical formulations comprising purified water, milk protein fluid and thickener, in particular a hydrogel and a lotion, and their use in treatment of radiation dermatitis, in particular in a two-step process for the treatment of radiation dermatitis.

The invention belongs to the technical field of medicines, and concretely relates to a traditional Chinese medicine for preventing radiodermatitis caused by nasopharyngeal carcinoma radiotherapy. The traditional Chinese medicine for preventing radiodermatitis caused by nasopharyngeal carcinoma radiotherapy is prepared from the following traditional Chinese medicinal raw medicines, by weight, 5-13 parts of cinnamon, 5-13 parts of aconite root, 25-35 parts of prepared rehmannia root, 6-14 parts of Rhizoma Alismatis, 6-14 parts of Cortex Moutan, 11-19 parts of Chinese yam, 11-19 parts of Cornus officinalis, 11-19 parts of Fructus Gardeniae, 6-14 parts of dendrobium, 11-19 parts of tortoiseshell and 2-4 parts of licorice root. The above traditional Chinese medicinal composition has the efficacies of kidney yang warming and invigorating, essence replenishing, blood nourishing, yin nourishing and fire purging, and can be clinically used for preventing the radiodermatitis caused by nasopharyngeal carcinoma radiotherapy.

The invention discloses a traditional Chinese medicine electuary for treating radiodermatitis and a preparation method, and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine electuary is prepared from leaves of broussonetia kazinoki sieb. et Zucc., manyinflorescenced sweetvetch roots, sansevieria trifasciata, roots of straight ladybell, roots of Amur ampelopsis, rhizoma atractylodis macrocephalae, radix ophiopogonis, licorice roots, mecodium microsorum Ching., radix codonopsis, australian cowplant roots or leaves, radix angelica sinensis, radix asparagi, roots of red-rooted salvia, all-grass of delavay pararuellia, korean pine seeds, common achyranthes herb, flos sophorae, glossy privet fruit, Chinese wolfberry fruit, radix pseudostellariae, david deer fat, Japanese pagodatree bark and Siberian saltbush fruit. According to the traditional Chinese medicine electuary, all the selected medicinal materials accord with the theory of monarch drugs, minister drugs, assistant drugs and guiding drugs, the drugs are used according to symptoms and pathogeny, the effects of tonifying the liver and kidney, replenishing Qi, enriching the blood, promoting blood circulation to remove blood stasis, clearing heat, removing toxicity, nourishing Yin, generating body fluid, removing swelling, relieving itching, closing sores, promoting tissue regeneration and moistening skin are achieved, the absorption effect is good, the curative effect is significant, toxic and side effects and clinical adverse reactions do not exist, and it is proved in clinic that the cure rate of the traditional Chinese medicine electuary to the radiodermatitis is high.

The invention discloses medicine extract submicron emulsion gel. The medicine extract submicron emulsion gel is prepared from the following raw materials in parts by weight: 20 to 50 parts of cortex moutan, 20 to 50 parts of rhizoma chuanxiong, 10 to 40 parts of safflower, 5 to 60 parts of herba selaginellae and 5 to 60 parts of herba geranii; the medicine extract submicron emulsion gel further comprises 50mg / g to 300mg / g of a medical oil phase, 5mg / g to 50mg / g of an emulsifier, 1mg / g to 50mg / g of an assistant emulsifier, 0.1mg / g to 35mg / g of a stabilizer, 0.1mg / g to 20mg / g of an antioxygen, 5mg / g to 50mg / g of a gel matrix and 0.5mg / g to 3mg / g of a preservative. The medicine extract submicron emulsion gel has the effects of promoting flow of qi and blood circulation, expelling wind and detoxifying, clearing heat and expelling dampness and is used for treating targeted medicine erythra, radiodermatitis and chemotherapeutic extravasation and has high effective rate, small toxic side effect and short course treatment.

The invention discloses an externally-applied traditional Chinese medicinal ointment for treating radiodermatitis. In the traditional Chinese medicine science, the property of radioactive rays belongs to heat; the radioactive rays are likely to damage a human body; the radiodermatitis is caused by excessive heat toxin, fire toxin acting on skin, and excessive heat induced flesh decay. Therefore, the externally applied traditional Chinese medicinal ointment is prepared from Chinese herbal medicines with functions of clearing away heat, detoxifying, cooling blood, nourishing blood, removing blood stasis and promoting tissue regeneration, including tetrastigma hemsleyanum diels et gilg, vernonia cinerea, Chinese mesona herb, lophatherum gracile, abrus cantoniensis hance, thesium chinense, brooklet anemone root, large-leaved cornel wood, spiral shell, rubus irenaus focke, cassie root and marigold. The ingredients are prepared to the externally-applied ointment by a manufacturing laboratory of the hospital. Through the clinical trial, the total effective rate is up to 96.9%, which is obviously better than the control group, so the externally-applied traditional Chinese medicinal ointment is worthy of clinical promotion and application.

Proline compounds as Granzyme B inhibitors, compositions that include the compounds, and methods for using the compounds. Methods for treating cutaneous scleroderma, epidermolysis bullosa, radiation dermatitis, alopecia areata, and discoid lupus erythematosus are provided.