21 results about "Topical cream" patented technology

The invention provides a simvastatin-cholesterol compound external emulsifiable paste and application thereof in preparation of a medicine for treating keratosis perspirioides. The simvastatin-cholesterol compound external use emulsifiable paste is prepared from simvastatin, cholesterol, pharmaceutically acceptable auxiliary materials and water. According to the simvastatin-cholesterol compound external emulsifiable paste disclosed by the invention, the simvastatin and the cholesterol are combined for use, so that the treatment effect of the simvastatin-cholesterol compound external emulsifiable paste on the keratosis is remarkably improved through the synergistic interaction of the simvastatin and the cholesterol.

The invention discloses a traditional Chinese medicine composition for moistening skin and relieving itching. The traditional Chinese medicine composition for moistening skin and relieving itching is prepared from fresh radix rehmanniae, fresh herba portulacae, peach kernels, almonds, radix angelicae sinensis, rhizoma bletillae, cortex moutan, cortex phellodendri, cortex dictamni, cortex lycii radicis, folium artemisiae argyi and raw liquorice. The invention further discloses external cream based on the traditional Chinese medicine skin moistening and itching relieving composition and a preparation method of the cream. The invention solves the problem of lack of an external traditional Chinese medicine cream preparation for skin itch and dryness caused by blood heat, blood deficiency, blood dryness and the like in the prior art.

This invention discloses a cream for treating psoriasis vulgaris and its preparation method: belonging to the technical field of psoriasis drug technology, this cream is made from the following raw materials in parts by weight: 1-5 parts Tripterygium wilfordii, 1-5 parts Euphorbia fischeriana, 10 parts Catechu, 8 parts Eucalyptus globulus, 10 parts Dictamnus dasycarpus, 10 parts Spatholobus suberectus, 10 parts Sophora flavescens, 10 parts Rehmannia glutinosa, 10 parts Angelica sinensis, 100-140 parts water, 40-50 parts emulsifier, and 0.05-0.1 parts preservative. The preparation method includes: decocting Tripterygium wilfordii, Euphorbia fischeriana, Catechu, Eucalyptus globulus, Dictamnus dasycarpus, Spatholobus suberectus, Sophora flavescens, Rehmannia glutinosa, and Angelica sinensis with water, then removing the herbs to obtain a medicinal paste; mixing the medicinal paste, emulsifier, and preservative and adding them to an emulsifier for emulsification to obtain the product. This formula can treat psoriasis vulgaris. As a topical cream for psoriasis, this invention has antifungal, antiviral, heat-clearing and blood-cooling, and antioxidant activities. It can inhibit epidermal cell proliferation, slow down the epidermal metabolic cycle, promote keratinization, inhibit sebum secretion, inhibit the growth environment of bacteria and fungi, and relieve itching caused by inflammation.

The invention provides a stable topical cream formulation of clascoterone for treatment dermatological conditions. More particularly, the invention relates to a stable topical aqueous cream formulation of clascoterone wherein clascoterone drug is in solubilized form in the cream.

An ophthalmic therapeutic treatment composition includes a topical cream containing a crosslinked acrylic acid polymer, an acrylamide / sodium acryloyldimethyl taurate copolymer, and an effective amount of an active pharmaceutical ingredient (API) dispersed in the topical cream. The ophthalmic therapeutic treatment composition and API are formulated for topical application and treatment of various disorders such as dry eye, presbyopia, intraocular pressure and blepharitis.

The invention relates to a topical cream containing a plethora of small sharp shards of a solid biopolymer (i.e., microneedles) which may or may not contain additional active ingredients or drugs, created in multiple sizes without molds or unusual processing equipment.

The present invention relates to the technical field of medical materials. Provided are a topical cream or patch for scar treatment and a preparation method therefor. The cream or patch is a topical preparation for scar treatment that combines a hormone, an antibiotic and a chemotherapeutic drug. By means of the synergistic effect of the three components, the cream or patch realizes a variety of effects such as sterilization, anti-inflammation, inhibition of fibroblast proliferation and angiogenesis, inhibition of scar hyperplasia, promotion of scar softening, and prevention of infection, thereby improving the efficacy of scar treatment. The preparation can be simply applied topically or used as a patch without injection, which greatly facilitates patient use and achieves the aim of scar prevention and treatment, thereby providing a multi-functional, safe and effective approach for scar treatment.

The invention provides the use of kinase inhibitors and derivatives of staurosporine, such as PKC412, to treat patients having epidermis bullosa simplex (BBS), epidermolytic hyperkeratosis, epidermolytic palmoplantar keratoderma, palmoplantar keratoderma, nonepidermolytic, pachyonychia congenita type 1, pachyonychia congenita type 2, or other intermediate filament associated diseases using oral or topical cream or ointment formulations of the same. The invention also provides the use of SRC and RAF kinase inhibitors, alone or in combination with PKC412, to treat intermediate filament associated diseases.

The invention is implemented into the category of transdermal topical agents for use in regulating the dilation of blood vessels. The IP-6, Inositol, and colloidal oatmeal Nerve Relaxing Transdermal Topical Cream, Gel, or Ointment for Raynaud's Syndrome is the first topical cream containing any or all of the following: IP-6, inositol, and colloidal oatmeal, with IP-6 as the carrier agent. The present invention will allow for the decrease in the time to full clinical effect, eliminate having to wear a patch of paper over the application site, and eliminate the problem of skin irritation due to the IP-6 delivering the colloidal oatmeal to the application area to provide extra soothing and moisturizing properties. The present invention is specifically and uniquely designed for ease of use and quick action of full clinical effect with the relaxation of nerve endings that lead to dilation of extremely constricted blood vessels in mind.

In this specification, C 7-20 A topical cream formulation comprising an alkane, a metal chelating agent and a buffer is described.

A topical cream composition is provided which comprises a mixture of a moisture barrier component, a steroid component, an antifungal component, and an antibiotic component. The combination of a moisture barrier, a steroid, an antifungal component, and an antibiotic component works together to optimally provide quick treatment and resolution for diaper dermatitis, also known as diaper rash, or other skin condition(s). The moisture barrier component provides a barrier between affected skin and diaper wetness; the steroid reduces swelling, itching, and / or other discomfort; the antifungal component treats any present fungal skin infection(s); and / or the antibiotic component treats any present bacterial skin infection(s). In one aspect, the topical cream comprises a composition of petroleum jelly, hydrocortisone cream, clotrimazole antifungal cream, and triple antibiotic ointment including bacitracin zinc, neomycin sulfate, and polymyxin B sulfate.

The invention discloses emulsifiable paste for treating eczema and dermatitis (seborrheic dermatitis) and a preparation method thereof, and belongs to the technical field of eczema and dermatitis (seborrheic dermatitis) medicines, the emulsifiable paste is prepared from the following raw materials in parts by weight: 6-10 parts of rhinacanthus nasutus, 6-10 parts of jatropha curcas, 6-10 parts of catechu, 6-10 parts of breynia fruticosa, 15-20 parts of coal tar, 40-80 parts of water, 40-50 parts of an emulsifier and 0.05-0.1 part of a preservative. The preparation method comprises the following steps: decocting the rhinacanthus nasutus, the jatropha curcas, the catechu and the breynia fruticosa with water, and then fishing out the medicinal materials to obtain medicine slurry; and mixing the medicine slurry, coal tar, an emulsifier and a preservative, adding into an emulsifying machine, and emulsifying to obtain the product. The external emulsifiable paste for eczema and dermatitis (seborrheic dermatitis) has the effects of astringing ulcers, astringing wounds and stopping bleeding, resisting viruses, dissipating blood stasis and diminishing swelling, relieving pain and itching, controlling pathogenic organisms on skin, promoting skin repair, inhibiting reproduction of viruses and fungi and the like.

A method of compounding a topical cream includes combining ingredients including lidocaine hydrochloride, 4%, topical solution, diclofenac sodium, 1.5%, topical solution, lidocaine hydrochloride USP powder, and diclofenac sodium powder.

This disclosure describes a cannabinoid-based nanoplatform for treating shingles, designed to enhance bioavailability and controlled release of active ingredients. The composition includes cannabinoids like cannabidiol (CBD) and cannabigerol (CBG), alongside flavonoids, polyphenols, and alkaloids, in oral and topical formulations. The oral capsule combines cannabinoids with polyphenols and flavonoids to provide systemic anti-inflammatory, antiviral, and neuroprotective effects, particularly for nerve pain and inflammation, including postherpetic neuralgia. The topical cream includes cannabinoids, capsaicin, and aloe vera, offering localized relief from pain, itching, and rash. The method targets both systemic and localized symptoms during the acute phase of shingles, aiming to inhibit varicella-zoster virus replication, disrupt viral assembly, and prevent viral release, while also providing immune modulation and anti-inflammatory benefits. The nanoplatform uses nano-emulsification techniques, producing particles smaller than 200 nm to ensure optimal delivery and therapeutic efficacy, offering comprehensive relief for shingles symptoms.

A topical cream or ointment is provided that provides for the binding to CB1 and / or CB2 receptors for the soothing of pain, inflammation of smooth muscle, tendons, ligaments, skeletal muscle, endothelial cell, synovial cell, peripheral nerve fibers, reduction of endothelial bruising, promotion of healing of endothelial bruising, and dermatological itch sensation wherein the improvement comprises providing the effect of cannabinoid using plant extracts. A topically administered formulation is also provided for treating anal mucosal inflammation, soothing of pain, inflammation of anal mucosal inflammation; reducing keratinocyte apoptosis; treating viral-associated epithelial damage, treating radiation dermatitis; and treating chemotherapy-induced dermatitis.

A cream formulation or topical use made of a mixture of naturally occurring biologically active phytochemical compounds that possess a variety of beneficial animal and human health effects. An extract from an aqueous extraction process or other active ingredients could be used in the cream formulation. The present invention generally provides for the preparation of cream formulations containing active ingredients that contain individually, or in combination, an analgesic, natural product extracts, or a protein or proteins from the tripartite motif family of proteins (TRIM). The analgesic will provide mitigation of pain during the healing process.

A topical cream or ointment is provided that provides for the binding to CB1 and / or CB2 receptors for the soothing of pain, inflammation of smooth muscle, tendons, ligaments, skeletal muscle, endothelial cell, synovial cell, peripheral nerve fibers, reduction of endothelial bruising, promotion of healing of endothelial bruising, and dermatological itch sensation wherein the improvement comprises providing the effect of cannabinoid using plant extracts.

The topical composition includes an amount of an antibiotic and a carrier that has skin penetration enhancement properties. The composition can include about 5 wt % Lidocaine, about 5 wt % Ketoprofen and about 5 wt % Doxycycline. The composition is readily formed as a consumer package. The composition has efficacy as a bite treatment and in particular bacteria conveyed via a tick bite.

The topical composition includes an amount of an antibiotic and a carrier that has skin penetration enhancement properties. The composition can comprise about 5 wt % Lidocaine, about 5 wt% Ketoprofen and about 5 wt % Doxycycline.

An ophthalmic therapeutic treatment composition includes a topical cream containing a crosslinked acrylic acid polymer, an acrylamide / sodium acryloyldimethyl taurate copolymer, and an effective amount of an active pharmaceutical ingredient (API) dispersed in the topical cream. The ophthalmic therapeutic treatment composition and API are formulated for topical application and treatment of various disorders such as dry eye, presbyopia, intraocular pressure and blepharitis.

The present invention discloses a topical cream composition of eflornithine or its pharmaceutically acceptable salts or prodrugs thereof with lavender oil as penetration enhancer and other excipients,