44 results about "Topical liquid" patented technology

An applicator has a reservoir adapted to contain a fluid and a pad in fluid communication with the reservoir. A tab serves to seal the fluid reservoir at a breakable connection, with breaking of the breakable connection allowing passage of fluid from the reservoir into the pad. The tab may be removable, or it may be embedded in the tab. Fluids with which use of the applicator is contemplated include sterilizable fluids for therapeutic applications to tissue, including topical liquids such as tissue adhesives for surgical applications, coatings and sealants. One candidate fluid is a cyanoacrylate prepolymer.

A topical liquid aerosol formulation for accurate metered dose delivery has been developed which includes a concentrate comprising a local anesthetic in a non-alcohol solvent and a hydrofluorocarbon (HFC) propellant. In the preferred embodiment, the concentration of the non-alcohol solvent in the concentrate is between about 75% and 85% by weight of the formulation. In the most preferred embodiment, the non-alcohol solvent is a water-soluble polyol such as ethylene glycol, propylene glycol, glycerol, diethylene glycol, dipropylene glycol, oligoalkylene glycols, liquid polyalkylene glycols, or combinations thereof. In one embodiment, the concentration of the local anesthetic in the concentrate is between about 15% and 25% by weight. In the preferred embodiment, the hydrofluorocarbon propellant is 1,1,1,2-tetrafluoroethane 1,1,1,2,3,3,3-heptafluoropropane or combinations thereof, in a concentration between about 35% and 65% by weight of the final formulation, more preferably between about 45% and 55% by weight of the final formulation. A particularly preferred formulation includes benzocaine, tetracaine, and butylaminobenzoate, wherein the concentration of benzocaine in the concentrate is 14% by weight, the concentration of tetracaine in the concentrate is 2% by weight, and the concentration of butylaminobenzoate in the concentrate is 2% by weight. It has been found that the formulation is more stable in the substantial absence of oxygen. The formulation is preferably administered using a metered dose device for release of a controlled amount of the local anesthetic.

The externally applied liquid asiaticoside preparation has effective component comprising asiaticoside 0.1-30.0 wt% and medicinal solvent 70.0-99.9 wt%. Its preparation process includes dissolving asiaticoside in the medicinal solvent, filtering, filling, sterilizing and packing. The present invention expands the clinical application of asiaticoside, and the abacterial preparation has high medicine concentration, high medicinal effect, no wound infection, and other advantages.

The invention provides a topical liquid antifungal composition containing an antifungal agent, a film-forming agent and a solvent. The composition is applied on the infected skin area to form a film that delivers the active agent. The invention also provides a method for treating a fungal infection on the skin by applying the topical antifungal composition that forms a film on the skin.

The invention relates to external liquid preparation capable of preventing secondary chromatosis from happening after skin trauma operations. Each part of the liquid preparation comprises radix paeoniae rubra, red-rooted salvia root, bamboo shaving extractives, water-soluble licoflavone, water-soluble bisabolol, 1000u / g of papain, heat-resistant superoxide dismutase (SOD), allantoin, azelaic acid derivatives, bee milk, water-soluble propolis, edetic acid, glycerol, ethyl p-hydroxybenzoate, tea polyphenol, sodium hydrogensulfite, and balance of high mineral water. The manufactured liquid preparation is used on skins by various methods of daubing, atomizing, mask paper adsorption attachment application, mask brushing application and the like. The external liquid preparation can promote blood circulation, removes dry heme, improves epithelial cells to grow and cure quickly, prevents secondary chromatosis from happening after skin trauma operations and has obvious whitening effects.

The invention relates to an externally used liquid preparation containing only iridoid glycoside and application thereof, belonging to the field of medicine. The externally used preparation of the invention contains 0.10-49.99% of the iridoid glycoside as an effective component and balance of adjuvant and water for manufacturing externally used preparations. The formulation of the preparation is externally used liquid lotion, externally used liquid liniment, aerosol, ointment and spraying agent.

Disclosed is externally used fibrauretine liquid for gynaecology and oral cavity, wherein the preparation essentially comprises fibrauretine as active constituent, and balancing adjuvant and water for preparing the externally used liquid preparation, the fibrauretine is alkaloid extracted from natural plant of fibraurea stem, calculated by dried product, it comprises Palmatine Hydrochloride C21H21O.HCl 20-98%. The dosage type includes externally used liquid lotion or liniment, foam aerosol, ointment, gargle or spray.

The present invention provides an external-use liquid skin-conditioning composition that not only reduces the sticky and friction sensations caused by the inclusion of tranexamic acid, but also has a rich body without feeling slimy and softens the skin after use. The composition comprises (A) 0.5 to 5 mass % of at least one hem selected from a group consisting of tranexarnic acid and derivatives thereof and (B) 0.005 to 1.5 mass % of carboxymethylcellulose, has a viscosity of no greater than 500 mPa·s at 30° C., and is transparent or semitransparent with an L value between 50 and 100 inclusive. Preferably the composition contains only carboxymethylcellulose as a thickener.

A topical liquid formulation is provided which contains a combination of three active ingredients for treating fleas and ticks in domestic animals. Total concentration of the active hydrophobic and hydrophilic ingredients can exceed 60 weight percent. In contrast to commonly available flea treatments, the new insecticidal composition is safe and effective for both felines and canines and a single topical application can be effective for at least several weeks.

The invention relates to an external liquid dressing for treating skin diseases as well as a preparation method and a use method of the external liquid dressing, belonging to the technical field of medicines. The external liquid dressing is prepared by the steps of moistening high-mountain sorbaria sorbifolia flowers or high-mountain sorbaria sorbifolia seeds into water for 20-60 minutes, adding 5-15 times of water, carrying out decoction twice with slow fire, and finally filtering decoction liquid, wherein the first decoction time is 2-4 hours, and the second decoction time is 1-3 hours. Theexternal liquid dressing is simple in component, only the high-mountain sorbaria sorbifolia flowers or the high-mountain sorbaria sorbifolia seeds are taken as the raw material, and the preparation method and the use method are simple and convenient. Besides, the raw materials are wide in sources and cheap, the production process flow is simple, the production speed is high, and batch production can be realized. The external liquid dressing is convenient to use and safe in clinical application and has no toxic or side effect. The external liquid dressing can take effect within 3-5 days, the diseases can be cured within about 30 days, and therefore, the external liquid dressing has good application prospects.

A liquid medicament for use on skin, epithelium, epidermis, body surface and so on containing a refined peanut oil and, for example, at least one agent which minimizes cell growth, inflammation or both.

The invention belongs to the field of medicines, and particularly relates to a simple auxiliary medicine applying tool. The tool is structurally characterized by comprising a smearing layer (1), a sponge (2) wrapping the smearing layer, a movable hinge fixing layer (3) located at the upper middle portion of the smearing layer (1), and a handle (6) for attaching and combining two sheet suspension movable hinges (4 and 5) on the top. By means of the tool, the defect that a user smears affected skin with liquid medicine and ointment by fingers is overcome, the potential hazards of skin infection spreading and finger bacterium cross-infection are avoided, the tool is simple in structure and convenient to use and can assist people in administrating an external liquid preparation or a semi-solid preparation, and skin, mucosa and wound surfaces are evenly smeared with medicine.

Provided is a device for treating tinea unguium which allows unrestricted treatment even for patients with basic diseases such as liver diseases, pregnant women and lactating patients and by which interindividual difference in the treatment can be avoided and antifungal agent for external use can be transdermally absorbed from the nail surface to the deep part of the nail economically, safely and efficiently within a short period of time without any side effects. A dome-shaped applicator, which is formed of a flexible material, which has an open part provided with a flange for adhesion and which is formed to have a larger film thickness in the periphery adjacent to the open part than the film thickness in other parts, is hermetically bonded to a surface of a nail. Then, the liquid antifungal agent for external use is fed into the dome-shaped applicator under pressure using an injector and is allowed to be efficiently penetrated into the deep part of the nail using positive pressure.

The invention relates to an external-use liquid medicine for treating gynecological inflammation. The external-use liquid medicine comprises the following raw materials of a radix sophorae flavescentis extract, a cortex phellodendri extract, a dandelion extract, a radix angelica sinensis extract, hippophae rhamnoides fruit flavone, a rose flower extract, egg white staphylococcus aureus enterotoxin, probiotics and domiphen bromide. The external-use liquid medicine disclosed by the invention is superhigh in effects of diminishing inflammation and killing bacteria; besides, through added super antigens, immunity can be rapidly regulated or activated by 2000-50000 times, body scent can be increased, hormone level can be balanced, the external-use liquid medicine can be quickly absorbed by skinand mucosa tissue, and the external-use liquid medicine can have the effects of repairing and treating on organs around the vagina.

A topical liquid agent for a nail and / or skin for prevention or treatment of dermatophytosis comprises a film-forming agent and a compound represented by the formula: wherein R1 represents hydrogen, C1-6 alkyl, or trifluoromethyl, R2 represents hydrogen, C1-6 alkyl, halogen, -COO(C1-6 alkyl), or (CH2)1-3COOR where R represents hydrogen or C1-6 alkyl, R3 represents hydrogen, C1-6 alkyl, amino, trifluoromethyl, or OR where R represents hydrogen or C1-6 alkyl, R4 represents hydroxyl, R5 represents hydrogen, C1-6 alkyl, hydroxyl, or halogen, R6 represents hydrogen, C1-6 alkyl, trifluoromethyl, halogen, amino, -NRaRb, nitro, hydroxy-C1-6 alkyl, -CONRaRb, -COO(C1-6 alkyl), -COOH, -(CH2)1-3COOR, or ORa where R represents hydrogen or C1-6 alkyl, Ra and Rb each represent hydrogen, C1-6 alkyl, or C1-6 acyl, R7 represents hydrogen, C1-6 alkyl, -OR where R represents hydrogen or C1-6 alkyl, or halogen, R8 represents hydrogen, C1-6 alkyl, hydroxyl, amino, or nitro, or a salt thereof.

A treatment regime for use in the treatment or prevention of dermatitis and inflammatory skin conditions, said regime comprising the administration of: a) between 50 mg and 3000 mg of a topical liquid or gel composition comprising between 1% w / w and 15% w / w cannabinoid, wherein the cannabinoid is dissolved in the liquid or gel composition.

The invention discloses an external used medicine for curing physical skin diseases and animal skin diseases, and a preparation method and application of the external used medicine. The main ingredient of the external used medicine is an NK cell stock solution, the NK cell stock solution is obtained through multiplication culture of an NK cell, and the NK cell stock solution is mixed with different pharmaceutical materials to prepare an external used liquid preparation or an external used cream preparation. Compared with the prior art, the external used medicine for curing physical skin diseases and animal skin diseases uses a cell factor excreted by the NK cell to diminish inflammation, prevents mosquito bite and infections of fungus and bacteria caused by papule, vesicle, wounds and anabrosis, has the advantages of stopping itching rapidly, curing thoroughly and having no toxic or side effects, etc., is particularly suitable for people with sensitive skin, infants, pregnant women and the like, and is also suitable for special crowds unsuitable for other medicines or hormone.

The invention provides an enconazole external liquid preparation, which is prepared by mixing enconazole, a solvent capable of dissolving enconazole and an emulsifier, and tests show that the appearance, the pH value and the purity of the enconazole external liquid preparation are basically unchanged after three months, so that the enconazole external liquid preparation can stably exist and is noteasy to degrade; the enconazole external liquid preparation disclosed by the invention can be used for effectively treating canine fungal skin diseases, and is simple in use method and good in antibacterial effect; the enconazole external liquid preparation disclosed by the invention contains menthol, and the external liquid preparation added with menthol has a relatively obvious relieving effecton discomfort, such as pruritus, of some pets when being used for treating fungal skin diseases; the enconazole external liquid preparation provided by the invention is mild to dogs and has no irritation to skin.

A topical liquid grip lotion is disclosed in multiple embodiments. The topical liquid grip lotion includes embodiments which are longer lasting that prior products and also includes embodiments which are formulated to provide relief from temporary user discomfort or pain that may associated with the underlying activity by the user in areas where the topical lotion is applied. The certain embodiments of the liquid sports grip aid / liquid hand chalk include about 1% lidocaine. In addition to increasing the amount of time of use per application, these embodiments provide a pain reducing agent which can be exceptionally useful for athletes and individuals who experience soreness in their hands, feet, and body when training. Alternative embodiments include formulations are substantially non-irritating due to the topical use of the product, and not intended for ingestion. It is unique that as not only do the embodiments immediately dry hands, feet, and body but can reduce soreness.

The invention belongs to the field of traditional Chinese medicine, and in particular relates to an external medicinal liquid for treating lymphoma and a preparation method thereof, comprising A component and B component, and the A component includes the following medicinal materials in parts by weight, Jin snake, white snake, Snake, hippocampus, sea dragon, sesame oil; component B includes gardenia, Alisma, pinellia, akebia, bupleurum, rehmannia glutinosa, kelp, astragalus, myrrh, cat's claw grass , white flower snake, belly snake, hippocampus, and sea dragon are put together into sesame oil, sealed and soaked, and then filtered to obtain liquid A; Kelp, Astragalus, Myrrh, Cat's Claw first put the above-mentioned herbal medicines in the pot, add water and boil until 1, take out the medicinal liquid and medicinal residues, put them in a jar, add 500 parts of 95% ethanol to soak for 3‑4 days , filter high-temperature sterilization to obtain liquid B, and mix the above-mentioned liquid A and liquid B according to liquid A: liquid B=0.5:1.0-1.5. The cost of treating lymphoma of the present invention is relatively low, the cycle is short, and the curative effect is good. Simple.

The object of the present invention is to provide a liquid preparation for external use which shortens the lag time of transdermal absorption and has excellent percutaneous permeability, and provides a liquid preparation for external use which reduces skin irritation. A percutaneous absorption type liquid preparation that can solve the above problems, which contains: (a) propylene glycol 40-98w / w%; (b) phosphatidylcholine 0.1-5w / w%; (c) oleyl alcohol and / or isodeca Octaconol 0.1-10w / w%; (d) drug 0.1-25w / w%. Furthermore, it is preferable to contain alkanolamine. The alkanolamine is preferably triethanolamine.

An object of the present invention is to provide a liquid composition for external application and a preparation for external application which are excellent in healing effect on skin ulcers including intractable skin ulcers such as bedsore (decubitus), diabetic skin ulcer and ischemic skin ulcer. The liquid composition for external application of the present invention as means for the resolution is characterized by comprising at least G-CSF (a granulocyte colony stimulating factor) as an active ingredient and 0.001% to 5% of alginic acid. The preparation for external application for treatment of a skin ulcer of the present invention is characterized by comprising the liquid composition for external application of the present invention as a medicinal ingredient.

The present invention addresses the problem of providing a liquid preparation for external application, which has a shortened transdermal absorption lag time and has excellent transdermal absorption properties. The present invention also addresses the problem of providing a liquid preparation for external application, which is less irritative to skin. The problems can be solved by a transdermal liquid preparation comprising: (a) propylene glycol in an amount of 40 to 98% by weight; (b) phosphatidylcholine in an amount of 0.1 to 5% by weight; (c) oleyl alcohol and / or isostearyl alcohol in an amount of 0.1 to 10% by weight; and (d) a medicine in an amount of 0.1 to 25% by weight. It is preferred that the transdermal liquid preparation additionally contains an alkanol amine. The alkanol amineis preferably triethanolamine.

The present invention relates to a novel melatonin-based formulation, particularly a topical liquid composition of melatonin (or analog thereof) suitable for use in intrauterine washing performed during medically assisted reproduction (e.g. in vitro fertilisation—IVF). Melatonin is notoriously unstable, especially in solution. The compositions of the invention exhibit high stability, which allows them to be kept for prolonged periods before their eventual use in the inhibition or prevention of embryonic implantation failure.

A treatment regime for use in the treatment or prevention of acne, said regime comprising the administration of: a) between 50 mg and 3000 mg of a topical liquid or gel composition comprising between 1% w / w and 15% w / w cannabinoid, wherein the cannabinoid is dissolved in the liquid or gel composition.

Disclosed is a liquid agent for external use wherein a tocopherol, a silk powder, a phospholipid such as a hydrogenated phospholipid, a carboxyvinyl polymer and water are mixed and the water content is set at 79-99% by weight. Such a liquid agent for external use is prevented from separation of the tocopherol and sedimentation of the silk powder, thereby achieving a stable dispersion state.

The present invention provides an external-use liquid skin-conditioning composition that not only reduces the sticky and friction sensations caused by the inclusion of tranexamic acid, but also has a rich body without feeling slimy and softens the skin after use. The composition comprises (A) 0.5 to 5 mass % of at least one item selected from a group consisting of tranexamic acid and derivatives thereof and (B) 0.005 to 1.5 mass % of carboxymethylcellulose, has a viscosity of no greater than 500 mPa s at 30° C., and is transparent or semitransparent with an L value between 50 and 100 inclusive. Preferably the composition contains only carboxymethylcellulose as a thickener.

The invention relates to an externally-applied traditional Chinese medicine liquid for treating chemotherapy drug induced phlebophlogosis. The traditional Chinese medicine liquid is capable of effectively solving the problem of the chemotherapy drug induced phlebophlogosis; the traditional Chinese medicine liquid is prepared from the following medicinal raw materials in parts by weight: 10-40 parts of purslane, 10-30 parts of herba houttuyniae, 6-20 parts of radix tinosporae, 10-40 parts of selfheal, 10-30 parts of fructus forsythia, 6-15 parts of dragon blood, 10-20 parts of safflower, 6-20 parts of rhodiola rosea, 6-20 parts of sarcandra glabra and 8-20 parts of semiaquilegia adoxoides. The traditional Chinese medicine liquid has the effects of promoting blood circulation to remove blood stasis, clearing away heat and toxic materials, and diminishing swelling and removing stasis, and is applicable to treating the chemotherapy drug induced phlebophlogosis and capable of relieving the pain of a patient and guaranteeing smooth chemotherapy; the traditional Chinese medicine liquid is simple to prepare, low in price, easily available in raw materials, and convenient and safe to use, and is an innovation of medicines for treating the chemotherapy drug induced phlebophlogosis.