This invention relates to the field of
biomedical technology. It provides a pharmaceutical composition comprising
fluvastatin and tanshinone as active ingredients, and further provides its application in the preparation of formulations for the prevention and / or treatment of
radiation-induced
lung injury. This invention utilizes the synergistic effect of
fluvastatin and tanshinone to intervene in the
pathogenesis of
radiation-induced
lung injury from multiple targets and pathways, significantly improving prevention and
treatment efficacy. It can alleviate the inflammatory symptoms of
radiation-induced pneumonia and
delay the progression of radiation-induced
pulmonary fibrosis, with low side effects, high safety, and wide applicability, providing a new
drug option and technical solution for the clinical prevention and treatment of radiation-induced
lung injury.