5 results about "Nitrendipine" patented technology

The invention discloses a waste recovery processing device for nitrendipine raw material medicine production, and relates to the technical field of raw material medicine production equipment.The waste recovery processing device comprises a recovery box and a plurality of conveying belts, the interior of the recovery box is hollow, and a collection box is arranged at the bottom of the recovery box; all the conveying belts are horizontally arranged in the recycling box, and the multiple conveying belts are arranged in an up-down spaced and staggered mode so that the material conveying path can be in an S shape; a liquid removing box is arranged in the recycling box, the bottom of the liquid removing box is rotationally connected with a liquid suction roller with the horizontal axis, a roller body, located below the rotating axis of the liquid suction roller, of the liquid suction roller is arranged outside the liquid removing box, and a gap is reserved between the liquid suction roller and the upper belt face of the corresponding conveying belt. A plurality of rows of microgrooves are formed in the surface of each liquid absorption roller, each row of microgrooves comprises a plurality of liquid absorption grooves which are distributed at intervals, the liquid absorption rollers are provided with solvent-philic coatings on the inner surfaces of the liquid absorption grooves, and the solvent-philic coatings are configured to be coatings with hydrophilic or alcohol-philic functions. The recovery device has the effect of improving the recovery efficiency of the raw material medicine production waste.

The application relates to application of a dihydropyridine compound or a salt thereof in preparation of a medicine for preventing and / or treating HPV infection, and belongs to the technical field of medicines and pharmaceutical preparations. The application provides application of the dihydropyridine compound or the salt thereof in preparation of the medicine for preventing and / or treating HPV infection, wherein the dihydropyridine compound is selected from one or more of nifedipine, amlodipine, lercanidipine, nimodipine, nitrendipine, nisoldipine, felodipine, benidipine, lacidipine and azelnidipine. The application scheme first reports the application of the dihydropyridine compound or the salt thereof in prevention and / or treatment of HPV, and in-vitro cell experiments are carried out through azelnidipine in the dihydropyridine compound, and further, the inhibiting effect of the dihydropyridine compound on HPV virus is verified through medicine administration of a mouse intradermal virus inoculation model and medicine administration of a mouse vaginal virus inoculation model.

The invention provides a candidate medicine for promoting the embryo implantation efficiency of an endometritis type RIF patient, and belongs to the technical field of embryo implantation. In order to solve the problem of how to discover potential intervention drugs aiming at the endometritis type RIF pathological mechanism, a five-step efficient drug screening strategy based on an in-vitro implantation model of the endometritis type RIF is adopted, so that the reliability and function correlation of a screening result are ensured. According to the invention, a candidate drug screened by adopting a five-step method efficient drug screening strategy comprises any one of the following drugs: evocamide, choline, nitrendipine, megestrol acetate, pranoprofen, oxaliplatin, adenine, ensorizole, baicalin and diacerein. Evocamide, choline and nitrendipine in the candidate drugs are three drugs with the best implantation promotion efficiency for patients with endometritis type RIF.

The invention relates to a production device for preparing nitrendipine through a three-step method, and relates to the technical field of medical product production equipment.The production device comprises a kettle body erected on the ground, a feeding port is formed in the top of the kettle body, a discharging pipe is arranged at the bottom of the kettle body, a stirring motor is installed at the top of the kettle body, and a stirring rod is installed on an output shaft of the stirring motor; the stirring rod extends into the kettle body, stirring blades are mounted at one end, extending into the kettle body, of the stirring rod, the kettle body comprises a lower kettle part, an upper kettle part and a dismounting and mounting part, the lower kettle part is erected on the ground, the upper kettle part is mounted on the lower kettle part in a clearance manner, the dismounting and mounting part is detachably mounted between the lower kettle part and the upper kettle part, and a filter screen is mounted at a position, close to the lower kettle part, of the dismounting and mounting part. The method has the effect of reducing the probability of residual refined nitrendipine crystals in the reaction kettle.

The invention relates to a nitrendipine tablet and a preparation method thereof. The nitrendipine tablet is prepared from the following components in parts by weight: 1 part of nitrendipine, 7.5 to 8.5 parts of lactose, 1.8 to 2.2 parts of sodium carboxymethyl starch, 2.6 to 3.4 parts of microcrystalline cellulose, 1.8 to 2.2 parts of povidone K30 and 0.1 to 0.2 part of magnesium stearate. The tablet provided by the invention is beneficial to uniform distribution of the content of nitrendipine by adjusting the components and the proportion. According to the method provided by the invention, the dissolution rate of the nitrendipine tablet meets the requirement by designing the charging sequence and mode of each auxiliary material.