Cream for treating eczema and dermatitis (seborrheic dermatitis) and preparation method thereof

Abstract

The invention discloses emulsifiable paste for treating eczema and dermatitis (seborrheic dermatitis) and a preparation method thereof, and belongs to the technical field of eczema and dermatitis (seborrheic dermatitis) medicines, the emulsifiable paste is prepared from the following raw materials in parts by weight: 6-10 parts of rhinacanthus nasutus, 6-10 parts of jatropha curcas, 6-10 parts of catechu, 6-10 parts of breynia fruticosa, 15-20 parts of coal tar, 40-80 parts of water, 40-50 parts of an emulsifier and 0.05-0.1 part of a preservative. The preparation method comprises the following steps: decocting the rhinacanthus nasutus, the jatropha curcas, the catechu and the breynia fruticosa with water, and then fishing out the medicinal materials to obtain medicine slurry; and mixing the medicine slurry, coal tar, an emulsifier and a preservative, adding into an emulsifying machine, and emulsifying to obtain the product. The external emulsifiable paste for eczema and dermatitis (seborrheic dermatitis) has the effects of astringing ulcers, astringing wounds and stopping bleeding, resisting viruses, dissipating blood stasis and diminishing swelling, relieving pain and itching, controlling pathogenic organisms on skin, promoting skin repair, inhibiting reproduction of viruses and fungi and the like.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of eczema and dermatitis (seborrheic dermatitis) drugs, and relates to a cream for treating eczema and dermatitis (seborrheic dermatitis) and a preparation method thereof. BACKGROUND

[0002] Eczema is a chronic inflammatory pruritic skin disease with polymorphic rash, symmetrical distribution, exudation tendency and self-conscious itching. The eczema population is extensive, regardless of age, gender and region, is prone to recurrence and needs long-term treatment. The acute stage is characterized by redness, edema, millet-sized papules, papulovesicles, blisters, erosion and exudation. The subacute stage is characterized by reduced redness and exudation, scabbed erosion, desquamation and chronic stage is mainly characterized by roughness, hypertrophy and lichenoid change. Eczema is prone to recurrence and seriously affects the quality of life of patients.

[0003] Dermatitis (seborrheic dermatitis) is a chronic inflammatory skin disease occurring in the site of sebum excretion, commonly seen in the head, face, chest and back, and is prone to occur in adults and infants. The cause is not clear, which may be related to heredity, sebum metabolism and the like. There may be symptoms such as erythematous rash, greasy, desquamation and itching. Dermatitis (seborrheic dermatitis) often occurs in sites with more sebaceous glands and abundant sebum secretion, such as scalp, face, chest and back. The typical skin lesions are yellow-red patches with oily scales attached, which may be accompanied by itching.

[0004] With the attention to eczema and dermatitis (seborrheic dermatitis) health diseases, there are numerous eczema and dermatitis (seborrheic dermatitis) drugs on the market.

[0005] At present, there are different forms of products related to eczema and dermatitis (seborrheic dermatitis) drugs, with different effects, and there may be hormone substances, which may cause dependence and other side effects in the use process.

[0006] The existing eczema and dermatitis (seborrheic dermatitis) drugs contain hormone substances which have side effects on the human body. Therefore, how to provide a safe and side-effect-free cream for treating eczema and dermatitis (seborrheic dermatitis) and a preparation method thereof is an urgent problem to be solved by the related personnel in the field. SUMMARY

[0007] Therefore, the present application provides a cream for treating eczema and dermatitis (seborrheic dermatitis) and a preparation method thereof.

[0008] In order to achieve the above-mentioned purpose, the present application adopts the following technical solutions:

[0009] A cream for treating eczema, dermatitis (seborrheic dermatitis) is prepared from the following raw materials in mass percentage: Ganoderma lucidum 6-10 parts, Aleurites fordii 6-10 parts, catechu 6-10 parts, black face god 6-10 parts, coal tar 15-20 parts, water 40-80 parts, emulsifier 40-50 parts, preservative 0.05-0.1 parts.

[0010] The present application has the following advantages: The present application is used as an external cream for treating eczema, dermatitis (seborrheic dermatitis), scabies, wound bleeding, skin itching, chronic ulcer, joint contusion, athlete's foot, ulcer non-convergence, aphtha, and has the effects of killing insects and relieving itching, resisting viruses, resisting fungi, dispersing stasis, relieving swelling, stopping bleeding, relieving itching and pain, killing insects and diuresis, collecting moisture and promoting tissue regeneration, converging and stopping bleeding, resisting diseases and microorganisms, clearing heat and removing dampness, promoting blood circulation and detoxification, resisting oxidation, inhibiting fungi, resisting bacteria, relieving inflammation, controlling pathogenic organisms on the skin, relieving swelling, promoting skin repair, inhibiting the reproduction of viruses and fungi, etc.

[0011] The combination of Ganoderma lucidum, Aleurites fordii, catechu, black face god and coal tar has very good effects on treating eczema, dermatitis (seborrheic dermatitis), and the main effects on eczema, dermatitis (seborrheic dermatitis) are killing insects and relieving itching, resisting viruses, resisting fungi, dispersing stasis, relieving swelling, stopping bleeding, relieving itching and pain, killing insects and diuresis, collecting moisture and promoting tissue regeneration, converging and stopping bleeding, resisting diseases and microorganisms, clearing heat and removing dampness, promoting blood circulation and detoxification, resisting oxidation, inhibiting fungi, resisting bacteria, relieving inflammation, controlling pathogenic organisms on the skin, relieving swelling, promoting skin repair, and inhibiting the reproduction of viruses and fungi, etc.

[0012] Ganoderma lucidum has the effects of killing insects and relieving itching, resisting viruses and fungi, and is used for treating eczema and scabies.

[0013] Aleurites fordii has the effects of dispersing stasis, relieving swelling, stopping bleeding, relieving itching and pain, killing insects and diuresis, and is used for treating wound bleeding, skin itching, chronic ulcer, joint contusion, eczema and athlete's foot.

[0014] Catechu has the effects of collecting moisture and promoting tissue regeneration, converging and stopping bleeding, resisting diseases and microorganisms, and is used for treating ulcer non-convergence, eczema and aphtha.

[0015] Black face god has the effects of clearing heat and removing dampness, promoting blood circulation and detoxification, resisting oxidation, relieving pain, and inhibiting fungi, and is used for treating eczema and dermatitis.

[0016] Coal tar has the effects of resisting bacteria, relieving inflammation, controlling pathogenic organisms on the skin, relieving pain, relieving itching, relieving swelling, promoting skin repair, resisting viruses, resisting fungi, and inhibiting the reproduction of viruses and fungi, and is used for treating eczema and seborrheic dermatitis.

[0017] This formula can treat eczema and dermatitis (seborrheic dermatitis), and eczema and dermatitis (seborrheic dermatitis) can occur anywhere on the body, are prone to recurrence, and require long-term treatment.

[0018] Further, the above-mentioned emulsifier is glycerol monostearate.

[0019] The beneficial effect of the further technical solution is that the skin can better absorb the cream.

[0020] Further, the preservative is nipagin.

[0021] The beneficial effect of the further technical solution is that the addition of 0.05-0.1 parts of the preservative ensures that the shelf life of the eczema and dermatitis (seborrheic dermatitis) is 24 months.

[0022] The present application also provides a preparation method of the cream for treating eczema and dermatitis (seborrheic dermatitis), comprising the following steps:

[0023] (1) The raw materials of the cream for treating eczema and dermatitis (seborrheic dermatitis) are weighed according to the above.

[0024] (2) The white Ganoderma lucidum, Aleurites fordii, catechu and black face spirit are boiled with water, and then the medicinal materials are taken out to obtain medicinal paste.

[0025] (3) The medicinal paste, coal tar, emulsifier and preservative are mixed and added to an emulsifier to emulsify to obtain the cream for treating eczema and dermatitis (seborrheic dermatitis).

[0026] Further, in step (2), the boiling process is as follows: first boiling at 110-120℃, and then changing to 80-90℃ for 20-30 minutes.

[0027] The beneficial effect of the further technical solution is that the success rate of the medicine is ensured and the medicine will not be boiled into paste.

[0028] Further, in step (3), the rotation speed of the emulsifier is 30-60 revolutions per minute, and the emulsification time is 30-60 minutes.

[0029] The beneficial effect of the further technical solution is that the emulsification effect is best at this rotation speed and time. DETAILED DESCRIPTION

[0030] The technical solutions in the embodiments of the present application will be described below in a clear and complete manner. Obviously, the described embodiments are only a part of the embodiments of the present application, but not all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.

[0031] Embodiment 1

[0032] The preparation method of the cream for treating eczema and dermatitis (seborrheic dermatitis) comprises the following steps:

[0033] (1) Take white crane Ganoderma 6 kg, euphorbia 6 kg, catechu 6 kg, black face god 6 kg, coal tar 12 kg, water 40 kg, glycerin monostearate 40 kg, propyl paraben 0.05 kg;

[0034] (2) White crane Ganoderma, euphorbia, catechu, black face god plus water decoction, first 110 ℃ boiling, then change to 80 ℃ decoction 20 minutes, then the medicine, get medicine paste;

[0035] (3) The medicine paste, coal tar, emulsifying agent and preservative mixed into emulsifying machine for emulsification, the speed of emulsifying machine is 30 revolutions per minute, emulsification time is 30 minutes, get the treatment of eczema, dermatitis (seborrheic dermatitis) cream.

[0036] Example 2

[0037] The preparation method of the cream for treating eczema and dermatitis (seborrheic dermatitis) comprises the following steps:

[0038] (1) Take white crane Ganoderma 8 kg, euphorbia 8 kg, catechu 8 kg, black face god 8 kg, coal tar 16 kg, water 60 kg, glycerin monostearate 45 kg, propyl paraben 0.07 kg;

[0039] (2) White crane Ganoderma, euphorbia, catechu, black face god plus water decoction, first 115 ℃ boiling, then change to 85 ℃ decoction 25 minutes, then the medicine, get medicine paste;

[0040] (3) The medicine paste, coal tar, emulsifying agent and preservative mixed into emulsifying machine for emulsification, the speed of emulsifying machine is 40 revolutions per minute, emulsification time is 40 minutes, get the treatment of eczema, dermatitis (seborrheic dermatitis) cream.

[0041] Example 3

[0042] The preparation method of the cream for treating eczema and dermatitis (seborrheic dermatitis) comprises the following steps:

[0043] (1) Take white crane Ganoderma 10 kg, euphorbia 10 kg, catechu 10 kg, black face god 10 kg, coal tar 20 kg, water 80 kg, glycerin monostearate 45 kg, propyl paraben 0.1 kg;

[0044] (2) White crane Ganoderma, euphorbia, catechu, black face god plus water decoction, first 120 ℃ boiling, then change to 90 ℃ decoction 30 minutes, then the medicine, get medicine paste;

[0045] (3) The medicine paste, coal tar, emulsifying agent and preservative mixed into emulsifying machine for emulsification, the speed of emulsifying machine is 60 revolutions per minute, emulsification time is 60 minutes, get the treatment of eczema, dermatitis (seborrheic dermatitis) cream.

[0046] Effect test

[0047] 1. Typical case

[0048] Method of administration: apply at any time, twice a day, the longer the cream is on the body, the better the effect is absorbed. During the medication period, avoid eating certain foods, do not take any traditional Chinese medicine, and keep clean and hygienic.

[0049] Case 1, Mr. Lv, male, 29 years old, 3 years of eczema patient.

[0050] Case analysis: The back is covered with red plaques and papules. Apply twice a day with Example 1 cream, the itching disappears after 3 days of medication, and the damaged area is significantly reduced after more than a month. Three months later, it is cured. Before recovery, three red plaques reappeared on the body, and the cream was used for a period of time to consolidate. One month after recovery, there was no recurrence, and there was no need to avoid eating certain foods. A total of 75 milliliters of cream was used in three months.

[0051] Case 2, Ms. He, female, 35 years old, 5 years of dermatitis (seborrheic dermatitis) patient.

[0052] Case analysis: The scalp and back are covered with yellow-red plaques, with oily scales attached to the surface, which is dermatitis (seborrheic dermatitis). Apply twice a day with Example 2 cream, the itching is reduced after one week of medication, the damaged area is significantly reduced after two months, and the scales are significantly reduced. Four months of medication cured the patient, and a total of 100 milliliters of cream was used in four months. The scalp and back did not have a recurrence phenomenon, and there was no recurrence after recovery.

[0053] Case 3, Ms. Liu, female, 51 years old, eczema patient for more than a decade.

[0054] Case analysis: The back and limbs have red plaques, rough and thickened, and are eczematous. Apply twice a day with Example 3 cream. The itching disappeared after 10 days of medication, and the damaged area was significantly reduced after more than two months. If the medication is not timely after the effect is seen, it will take five months to recover. There was no recurrence after recovery, and a total of 150 milliliters of cream was used in five months.

[0055] 2. Conclusion: Patients with mild and moderate eczema and dermatitis (seborrheic dermatitis) mainly have lesions on the back, chest, scalp, and limbs. For mild patients, recovery is achieved in about 3 months of medication. For moderate and severe patients, recovery is achieved in about 4-5 months of medication.

[0056] The description of the disclosed embodiments enables a person skilled in the art to implement or use the present application. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present application. Therefore, the present application will not be limited to these embodiments shown herein, but will conform to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A cream for treating eczema, dermatitis (seborrheic dermatitis), characterized by, The cream is prepared from the following raw materials by weight: Ganoderma lucidum 6-10 parts, Jatropha curcas 6-10 parts, Uncaria tomentosa 6-10 parts, Uncaria gambier 6-10 parts, coal tar 15-20 parts, water 40-80 parts, emulsifier 40-50 parts, and preservative 0.05-0.1 parts.

2. The cream for treating eczema, dermatitis (seborrheic dermatitis) according to claim 1, characterized by, The emulsifier is glycerin monostearate.

3. The cream for treating eczema, dermatitis (seborrheic dermatitis) according to claim 1, characterized by, The preservative is ethylparaben.

4. A method for preparing a cream for treating eczema, dermatitis (seborrheic dermatitis), characterized by, The method comprises the following steps: (1) weighing the raw materials for preparing the cream for treating eczema and dermatitis (seborrheic dermatitis) according to any one of claims 1-3; (2) decocting Ganoderma lucidum, Jatropha curcas, Uncaria tomentosa, and Uncaria gambier with water, and then taking out the medicinal materials to obtain medicinal paste; (3) mixing the medicinal paste, coal tar, emulsifier, and preservative, and then adding them into an emulsifying machine to emulsify, so as to obtain the cream for treating eczema and dermatitis (seborrheic dermatitis).

5. The method for preparing a cream for treating eczema and dermatitis (seborrheic dermatitis) according to claim 4, characterized in that, In step (2), the decocting process is as follows: first boiling at 110-120 ℃, and then changing to decocting at 80-90 ℃ for 20-30 minutes.

6. The method for preparing a cream for treating eczema and dermatitis (seborrheic dermatitis) according to claim 4, characterized in that, In step (3), the rotating speed of the emulsifying machine is 30-60 rpm, and the emulsifying time is 30-60 minutes.