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50 results about "Cream preparation" patented technology

Cheese ice cream capable of being cryopreserved and preparation method thereof

The invention discloses cheese ice cream capable of being frozen and preserved and a preparation method thereof, and the preparation method comprises the following steps: filtering raw milk, standardizing the milk, sterilizing, fermenting and removing whey to obtain cheese curd; placing the cheese curd in a steam engine for treatment to obtain a pretreated cheese material; preparing a mixed material from the pretreated cheese material, milk powder, cane sugar, glucose powder, malt syrup, a compound stabilizer, water, cream cheese, condensed milk, iced yolk and cream; and performing sterilization, ultrasonic homogenization and aging on the mixture, and performing freezing treatment under the condition that an alternating static magnetic field and an alternating electric field are alternated during stirring and air inflation, thereby obtaining the product. By adding the compound stabilizer, the cheese ice cream is more stable in structure and easy to maintain taste; ice crystals are fine and uniform in texture under the combined action of the alternating magnetic field and the electric field, so that the soft and glutinous feeling and aftertaste effect of the ice cream are improved.
Owner:BEIJING CARIO FOOD SCI & TECH CO LTD

Novel freckle-removing and tissue-regeneration-promoting cream preparation based on micro-emulsion technology and preparation method thereof

The invention relates to the technical field of freckle removing and tissue regeneration promoting cream preparations, in particular to a novel freckle removing and tissue regeneration promoting cream preparation based on a microemulsion technology and a preparation method of the novel freckle removing and tissue regeneration promoting cream preparation. 10 to 30 parts of an oil phase; 40 to 70 parts of a water phase; 7 to 23 parts of a surfactant; 5 to 18 parts of a cosurfactant; 0.7-3 parts of a stabilizer; 0.1 to 0.5 part of a preservative; due to the application of the microemulsion system, the problem of stability of a traditional emulsion is solved, the preparation keeps good physicochemical properties in the long-term storage process, the transdermal infiltration capacity of active ingredients is remarkably improved due to the nanoscale microemulsion droplet size, and the defect of low bioavailability of a traditional preparation is overcome; the unique traditional Chinese medicine compound design realizes the synergistic interaction of multiple effects of removing freckles, promoting tissue regeneration, resisting oxidation and the like, and provides comprehensive protection and repair for skin health.
Owner:SOUTHERN MEDICAL UNIVERSITY

Preparation method of sea-buckthorn ointment

The invention discloses a preparation method of sea-buckthorn ointment, and relates to the technical field of massage cream preparation, the preparation method of the sea-buckthorn ointment is realized through sea-buckthorn ointment preparation equipment, the sea-buckthorn ointment preparation equipment comprises an equipment shell, the top of the inner side of the equipment shell is provided with a driving mechanism, and the driving mechanism is connected with the equipment shell. An inner stirring mechanism is arranged at the bottom end of the driving mechanism, a separated containing mechanism is arranged at the bottom of the inner side of the equipment shell, and an annular inner partition plate in the separated containing mechanism divides an inner cavity of the heating container into an outer cavity used for containing a component A and an inner cavity used for containing a component C; and an outer stirring mechanism is arranged in the separated accommodating mechanism. According to the invention, not only can proportioning ratio imbalance caused by excessive residues during component A transfer be avoided, but also overlarge mixing temperature error caused by temperature loss of the component A in the transfer process can be avoided, the quality of the finished product of the sea-buckthorn ointment is ensured, and the method is more suitable for industrial production of the sea-buckthorn ointment.
Owner:JIANGXI MISJIE BIOTECHNOLOGY CO LTD

Ultrahigh-temperature single cream preparation device and method for milk tea

The invention relates to the technical field of cream preparation devices, and discloses an ultrahigh-temperature single cream preparation device and method for milk tea, the device comprises a bottom plate and a packaging machine, the packaging machine is fixedly mounted on the bottom plate, a conveying frame is fixedly mounted on the upper surface of the bottom plate, and a first conveying belt is mounted in the conveying frame; and a second conveying belt is mounted on the outer side of the conveying frame. According to the device, multiple pieces of bottled cream are distributed and conveyed one by one through the distribution disc, and the driving belt is controlled by the driving mechanism to drive the U-shaped rod and the stop lever to intermittently move, so that the U-shaped rod can intermittently push the multiple pieces of bottled cream intercepted on the first conveying belt to the second conveying belt; the multiple pieces of bottled cream are conveyed to the packaging machine to be packaged through the second conveying belt, manual arrangement of the multiple pieces of bottled cream is not needed, the labor intensity of operators can be effectively relieved, and the packaging efficiency of the bottled cream is improved.
Owner:BEI YAN RU ZHI PIN (SHAN DONG) YOU XIAN GONG SI

Paste preparation blending device and method

The invention discloses a cream preparation blending device and method, and belongs to the technical field of cream processing equipment.The cream preparation blending device comprises a driving assembly, the driving assembly comprises a heating pot, a pot cover is fixedly connected to the upper end of the heating pot, a rotating shaft is rotatably connected to the pot cover, a fixing pipe is rotatably connected to the upper end of the rotating shaft, and a first gear is fixedly connected to the rotating shaft; a conveying assembly is fixedly connected to the upper side wall of the pot cover, a motor plate is fixedly connected into the conveying assembly, a second gear is rotationally connected to the lower side wall of the motor plate and rotationally connected with the first gear, and a motor is fixedly connected to the upper side wall of the motor plate; according to the device, through the design that the stirring shaft is not in contact with the pot bottom, the high-temperature pump is matched, the flow speed of the paste at the pot bottom is increased through the impact force of fluid of the paste, and in this way, the sufficient stirring effect can be achieved; and the phenomenon that the ointment is burnt in a pot in the long-time heating process can be effectively prevented.
Owner:SHANDONG GUZHITENG BIOTECHNOLOGY GRP CO LTD

Semitransparent skin-care face cream based on medium-temperature hot pot process as well as preparation method and application of semitransparent skin-care face cream

The invention discloses a semitransparent skin-nourishing face cream based on a medium-temperature hot pot process and a preparation method and application thereof, belongs to the technical field of cosmetics, and aims at solving the problems that in the prior art, in the face cream preparation process, a high-temperature processing process can destroy the activity of natural extracts; and the technical problem of how to enable the face cream to be semitransparent through formula system combination is solved. The preparation method of the semitransparent skin-care face cream based on the medium-temperature hot pot process comprises the following steps: putting a phase A into an emulsifying pot, and stirring and heating to 80-85 DEG C; adding the phase B into the emulsifying pot, stirring and heating to 80-85 DEG C, and then cooling to 60-65 DEG C; sequentially adding the phase A, the phase B, the phase C and the phase D into an emulsifying pot to enable the materials to be uniform, and cooling the materials to 53-57 DEG C to obtain cream; and filling the cream to obtain the prepared semitransparent skin-nourishing face cream based on the medium-temperature thermal tank process. The semitransparent face cream is prepared by designing a component compounding system.
Owner:澳亚化妆品研究开发(广州)有限公司

Traditional Chinese medicine composition capable of moistening skin and relieving itching, external cream and preparation method of external cream

The invention discloses a traditional Chinese medicine composition for moistening skin and relieving itching. The traditional Chinese medicine composition for moistening skin and relieving itching is prepared from fresh radix rehmanniae, fresh herba portulacae, peach kernels, almonds, radix angelicae sinensis, rhizoma bletillae, cortex moutan, cortex phellodendri, cortex dictamni, cortex lycii radicis, folium artemisiae argyi and raw liquorice. The invention further discloses external cream based on the traditional Chinese medicine skin moistening and itching relieving composition and a preparation method of the cream. The invention solves the problem of lack of an external traditional Chinese medicine cream preparation for skin itch and dryness caused by blood heat, blood deficiency, blood dryness and the like in the prior art.
Owner:WENZHOU TRADITIONAL CHINESE AND WESTERN MEDICINE HOSPITAL

Fusidic acid cream and preparation method thereof

The present invention provides a fusidic acid cream preparation, comprising an active ingredient fusidic acid, an aqueous phase part and an oil phase part, wherein the aqueous phase part comprises glycerol, a preservative and purified water; the oil phase part comprises an oily base and an emulsifier; further, in order to avoid the increase of impurities caused by the addition of antioxidants to the excipients due to their thermal instability, the cream does not contain antioxidants. After testing, the stability of the fusidic acid cream of the present application is better than that of the commercially available reference preparation, and it can maintain the stability of the paste properties and active ingredients under high temperature, high humidity, low temperature, freeze-thaw and light conditions. The maximum single impurity and total impurity content in the product do not increase significantly, and the quality is controllable. At the same time, the preparation process of the fusidic acid cream disclosed in the present application is simple and easy to industrialize.
Owner:FRONT PHARM PLC

Feeding device for cream preparation small materials

The invention relates to the technical field of cream production, in particular to a cream preparation small material feeding device which comprises a base, a feeding barrel is fixedly arranged above the base, a second material taking mechanism is arranged in the middle of the feeding barrel, a plurality of feeding grooves are evenly formed in the front portion of the top face of the feeding barrel, and first discharging openings are formed in the lower ends of the inner side walls of the feeding grooves. And the second material taking mechanism comprises a material taking barrel slidably connected with the middle of the feeding barrel, a first material taking mechanism is arranged on the lower portion of the material taking barrel and comprises a bearing ring located below the first discharging port, and the inner side wall and the outer side wall of the bearing ring are slidably connected with the inner wall of the feeding barrel and the outer wall of the material taking barrel correspondingly. The first material taking mechanism is arranged, the preparation amount of small cream materials in each round can be reduced through the first material taking mechanism, workers do not need to manually weigh and proportion raw materials, manpower and material resources needed by cream production are effectively reduced, and meanwhile controllability and flexibility of the total production amount are improved.
Owner:QINGDAO KESONG FOOD CO LTD

Preparation method of micro-capsule wrapped high-stability active face cream based on digital simulation driving

The invention discloses a micro-capsule wrapped high-stability active face cream preparation method based on digital simulation driving, and relates to the technical field of face cream preparation, the micro-capsule wrapped high-stability active face cream preparation method comprises the following steps: constructing a multi-physical field coupling simulation model, and importing skin microenvironment parameters, micro-capsule structure parameters and active component parameters; shell degradation, active molecule diffusion and stratum corneum permeation full-chain dynamic behaviors of the microcapsules on the skin surface are simulated through the model, and a release rate-absorption rate matching curve is output; reversely adjusting the capsule material components and the shell crosslinking degree of the microcapsules according to the curve; constructing a capsule material molecular dynamics simulation model, analyzing capsule material molecular chain degradation paths and key sites in different environments, and designing a capsule material molecular structure; and constructing a digital twinborn body, simulating and predicting raw material fluctuation influence, and adjusting preparation parameters. According to the method, the micro-capsule parameters, the capsule material molecular structure and the preparation parameters are regulated and controlled by combining multi-dimensional parameters through the synergistic effect of a multi-physical field coupling simulation system, a capsule material molecular dynamics simulation system and a digital twin three-stage simulation system.
Owner:GUANGDONG QUANXIN PHARMACEUTICAL TECHNOLOGY CO LTD

A compound essential oil for relieving primary dysmenorrhea and preparation method thereof

The invention discloses a compound essential oil for relieving primary dysmenorrhea and a preparation method thereof. The compound essential oil for relieving primary dysmenorrhea includes limonene, gingerol, α-terpinene acetate, β-sesquiphellandrene, eucalyptol, p-cymene, β-phellandrene, γ-terpinene, α-pinene, β-bisabolene, α-curcumene, trans-caryophyllene, camphene, β-pinene, myrcene, linalool, cis-11-eicosenoic acid, 3-thujacene, α-farnesene, sabinene, 3-carene, nonanoic acid, α-copaene, β-elemene. The present invention has a significant effect of relieving primary dysmenorrhea, and has good safety. In addition, essential oil preparations are easier to penetrate into the skin than cream preparations, and are more likely to activate cells after being absorbed by the skin.
Owner:POLI AROMATIC PHARMACEUTICAL TECHNOLOGY (SHANGHAI) CO LTD ROOM

Quantitative analysis of four anions in cream preparations

The present invention provides a method for simultaneously determining the content of four or more anions in a cream preparation by using a liquid chromatography coupled to a charged aerosol detector (CAD), wherein the four or more anions include chloride ions, nitrate ions, phosphate ions and sulfate ions, and the liquid chromatography conditions include: a chromatographic column: a C18 column, a mobile phase A: a 10 mM n-octylamine aqueous solution, the pH value is adjusted to 4.5 ± 0.5, a mobile phase B: acetonitrile, gradient elution is adopted, and the detector is a charged aerosol detector (CAD). The determination method of the present invention can accurately quantify the four anions in the cream preparation, has low detection cost, simple sample preparation, short total detection time, high specificity and accuracy.
Owner:CUTIA THERAPEUTICS (WUXI) CO LTD

Glycyrrhizinic acid monoammonium cream preparation, method for preparing the same, and use thereof

PendingCN122624365AOil phaseAntibacterial agent
This invention discloses a glycyrrhizic acid monoammonium cream formulation, its preparation method, and its applications. The glycyrrhizic acid monoammonium cream formulation of this invention comprises glycyrrhizic acid monoammonium salt, oil phase raw materials, emulsifiers, and antibacterial agents. The preparation process is simple and easy to operate. The resulting glycyrrhizic acid monoammonium cream exhibits good stability, strong moisturizing properties, and anti-inflammatory and antioxidant effects. The glycyrrhizic acid monoammonium cream of this invention can be used externally in cosmetics or pharmaceuticals, providing excellent skin care and therapeutic effects.
Owner:JIANGSU QIRUI MEDICINE TECH CO LTD

Photo-thermal stable fluticasone propionate emulsifiable paste preparation and preparation process thereof

PendingCN121818513AOrganic active ingredientsAntipyreticFluticasone propionatePropanoic acid
The invention discloses a photothermal stable fluticasone propionate emulsifiable paste preparation and a preparation process thereof, and relates to the technical field of external emulsifiable paste. Comprising the following steps: step 1, (1) adding isopropyl myristate and cetostearyl alcohol into liquid paraffin, mixing, heating and stirring to obtain an oil phase; (2) adding citric acid, sodium citrate, imidazolidinyl urea, a photo-thermal stabilizer and polyethylene glycol hexadecyl-octadecyl ether into deionized water, mixing, heating and stirring to obtain a water phase; (3) adding fluticasone propionate and propylene glycol into deionized water, heating and stirring to obtain a fluticasone propionate solution; and 2, adding the water phase into the oil phase, stirring, adding a fluticasone propionate solution, uniformly mixing, adding propyl hydroxybenzoate and methyl hydroxybenzoate, and standing at room temperature to obtain the fluticasone propionate emulsifiable paste preparation. The fluticasone propionate emulsifiable paste preparation prepared by the invention has good photo-thermal stability and meets the requirements of external emulsifiable paste.
Owner:JIANGSU SEMPOLL PHARMA

Nadifloxacin emulsifiable paste and preparation method thereof

The invention relates to a nadifloxacin emulsifiable paste and a preparation method thereof, the nadifloxacin emulsifiable paste comprises an active component nadifloxacin and pharmaceutic adjuvants, and is a water-in-oil or oil-in-water external emulsifiable paste preparation. The chemical and physical stability of the product is remarkably improved by adopting a buffer type alkaline hydrotropy system formed by sodium hydroxide and diethanol amine in a synergistic manner, an edetate disodium metal chelating agent and a specifically-formed composite oil phase matrix and combining a vacuum emulsification and double homogenization process; and the preparation process parameters are clear, the industrial amplification can be realized, and the technical problems of poor stability, large quality fluctuation, limited curative effect and the like of the existing nadifloxacin external preparation are solved.
Owner:JIANGSU YABANG QIANGSHENG PHARMA

High-stability mometasone furoate cream and processing technology thereof

The invention discloses high-stability mometasone furoate emulsifiable paste and a processing technology thereof, and relates to the technical field of emulsifiable paste preparations. A double-emulsification-system preparation process is adopted, the stability of the cream is remarkably improved, firstly, main drug active ingredients are prepared into submicron emulsion through dispersion and homogenization to form a first emulsification system (W / O) to play a role in primary protection, secondly, dispersion is added into a water phase to form an oil-in-water particle structure, and then the dispersion and an oil phase are emulsified to form a second emulsification system (O / W / O) to play a role in secondary protection. The mometasone furoate emulsifiable paste with high stability is prepared by adding auxiliary materials such as titanium dioxide and starch aluminum octenylsuccinate, so that the bioavailability of mometasone furoate is improved; by cooperating with excellent oxidation resistance of 4-vinyl guaiacol, gallic acid and glycyrrhizic acid, the oxidation resistance of the cream is remarkably improved, and the long-acting stability of the cream is further ensured.
Owner:JIANGSU SEMPOLL PHARMA

Moisturizing hand cream and preparation method thereof

InactiveCN119327338ACosmetic preparationsToilet preparationsShea Nut ButterGlycerol
The invention relates to the technical field of production of moisturizing hand cream products, in particular to moisturizing hand cream and a preparation method thereof.The moisturizing hand cream is prepared from, by mass, 8-12 parts of glycerinum, 6-10 parts of vaseline, 3-7 parts of allantoin, 5-9 parts of shea butter and 2-6 parts of vitamin E. The preparation method includes the steps that the moisturizing hand cream is prepared, the moisturizing hand cream is prepared through the preparation device of the moisturizing hand cream, discharging of materials and water for water bath is facilitated by arranging a discharging structure, a discharging pipe and a water outlet pipe, and by means of the design of the discharging structure, a second motor is used for driving a rotating block and an extrusion wheel to alternately extrude a discharging hose forwards and backwards; the discharging speed of vaseline and shea butter with high viscosity is effectively increased, the problem that the production progress is affected due to slow discharging is solved, and the production efficiency is improved.
Owner:KUNMING YIHEWEI TECHNOLOGY CO LTD

Preparation method of environment-friendly black soldier fly oil-peptide composite system antioxidant antibacterial hand cream

The application provides an environment-friendly black soldier fly oil-peptide composite system antioxidant antibacterial hand cream preparation method, and relates to the technical field of cosmetics. The hand cream preparation method specifically comprises the following steps: S1. black soldier fly oil extraction, S2. black soldier fly oil purification, S3. black soldier fly antibacterial peptide fermentation preparation, and S4. hand cream compounding. The insect oil extraction rate reaches 87.0%, the antibacterial peptide is prepared by fermentation of insect residues without raw material waste, and the application is in line with the environmental protection concept. The constructed insect oil-antibacterial peptide composite system replaces chemical additives with natural ingredients, the DPPH free radical scavenging rate is 48.5%, and the antibacterial effect on staphylococcus aureus and escherichia coli is remarkable. The product pH is close to the physiological value of the skin, has no irritation, can continuously moisturize for more than 8 hours, and is excellent in heat resistance, cold resistance and light stability, and meets the industry standard. The enzymolysis and fermentation process is mild, there is no organic solvent residue, the process is simple and controllable, is suitable for industrialized mass production, fills the technical blank of the application of the insect oil-peptide composite system in cosmetics, and has the advantages of high safety, high efficiency, low cost, no pollution, no waste, no harm to the human body, and the like.
Owner:GANNAN NORMAL UNIV

Mannuronates, guluronates, and guluronate topical gels or creams and methods of making same

The present invention relates to a gel or cream formulation for topical use, the formulation comprising beta-D-mannuronic acid or alpha-L-guluronic acid or a mixture of beta-D-mannuronic acid and alpha-L-guluronic acid, their oligomers or their pharmaceutically acceptable salts, where, based on 100 g of the gel or cream formulation, the content of the beta-D-mannuronic acid or alpha-L-guluronic acid or the mixture of beta-D-mannuronic acid and alpha-L-guluronic acid or alpha-L-guluronic acid or alpha-L-guluronic acid or alpha-L-guluronic acid or alpha- the total amount of beta-D-mannuronic acid or alpha-L-guluronic acid or a mixture of beta-D-mannuronic acid and alpha-L-guluronic acid, their oligomers or their pharmaceutically acceptable salts is from 0.5 g to 40 g, said formulation further comprising caffeic acid. Furthermore, the present invention relates to a gel or cream formulation for topical use in a method of treating inflammation and / or any inflammatory response and / or pain, as well as a method of preparing the gel or cream formulation.
Owner:FLOATING KNIGHT BIOTECH PTE LTD

Ketoconazole cream and preparation method thereof

The ketoconazole emulsifiable paste comprises ketoconazole, an emulsifier, a buffer pair, a stabilizer, an antibacterial agent and an oily matrix which are used as active ingredients, the invention provides a preparation method of the ketoconazole emulsifiable paste, overcomes the problem of poor stability of a ketoconazole emulsifiable paste preparation, and obtains the ketoconazole emulsifiable paste which can be stored for a long time, can keep the paste uniform and stable, has low ketoconazole D impurity content, and can be used for preparing the ketoconazole emulsifiable paste. And the characteristics of the paste and the stability of the active ingredients can still be kept in different environments (including temperature, humidity and illumination).
Owner:NANJING YISHU PHARMACEUTICAL INFORMATION TECHNOLOGY CO LTD

Preparation method of pollen itching-relieving and pain-relieving preparation

The invention discloses a preparation method of a pollen itching-relieving and pain-relieving preparation. The medicine formula of the pollen itching-relieving and pain-relieving preparation consists of a radix angelicae extract, a short-pedicel aconite root extract, a radix trichosanthis extract, a frankincense and myrrh mixed extract, frankincense and myrrh mixed volatile oil, borneol, camphor, peppermint oil and eucalyptus oil, methyl cellulose and dipolyglycerol dioleate are used as water-phase emulsifiers, and ascorbic acid is used as an antioxidant. The preparation is cream, is uniform and fine in texture, fine and smooth in appearance and good in flowability, is free of layering and foaming phenomena after centrifugation, and is free of layering and foaming phenomena after heat-resistant and cold-resistant stability tests.
Owner:GUIZHOU HONGKANG PHARMA

Medicinal composition for treating dermatitis as well as preparation method and application thereof

PendingCN121731322AOrganic active ingredientsAerosol deliveryInfantile atopic dermatitisVitamin
The invention discloses a medicinal composition for treating dermatitis and a preparation method and application thereof, and relates to the technical field of medicines.The medicinal composition is cream, the medicinal composition comprises vitamin E and desonide, based on the total weight of the cream, the content of the desonide is 0.0025%-0.045%, preferably 0.025%, and the content of the vitamin E is 0.025%-0.045%, preferably 0.025%. The invention aims to solve the technical problem that a desonide vitamin E compound emulsifiable paste preparation which is specially designed for infant atopic dermatitis and is low in concentration, fixed in proportion and stable in quality is lacked in the prior art.
Owner:WUHAN CHILDRENS HOSPITAL

Lindera reflexa hemsl essential oil liposome emulsifiable paste as well as preparation method and application thereof

The invention relates to the technical field of emulsifiable paste preparation, in particular to lindera reflexa hemsl essential oil liposome emulsifiable paste and a preparation method and application thereof. The preparation method comprises the following steps: dissolving the lindera reflexa hemsl essential oil, lecithin and cholesterol in a solvent, and evaporating the solvent to form a reaction material; performing ultrasonic mixing on the reaction material and a pH regulator to obtain lindera reflexa essential oil liposome; heating and mixing the lindera reflexa hemsl essential oil liposome and a first emulsifier to form a water phase solution; heating and melting liquid paraffin, octadecanol and a second emulsifier to form an oil-phase mixture; and mixing the oil phase mixture with the water phase solution, and emulsifying to obtain the lindera reflexa hemsl essential oil liposome emulsifiable paste. The lindera reflexa hemsl essential oil and the preparation method thereof have the advantages that the problem of poor stability of the lindera reflexa hemsl essential oil is solved, the bioavailability and the release efficiency of the lindera reflexa hemsl essential oil are improved through the controlled release effect of the lindera reflexa hemsl essential oil liposome, meanwhile, the preparation method of the emulsifiable paste is simple and easy to implement and has the potential of industrial production, and a new way is opened up for deep processing of lindera reflexa
Owner:XINYANG AGRI & FORESTRY UNIV

Composition containing sea cucumber peptide, sophocarpidine and inositol and preparation method thereof

The present invention relates to a moisturizing, itching relieving, soothing and repairing cream, the cream comprises sea cucumber peptide, sophocarpidine, inositol, a moisturizing agent, an emulsifier, an antioxidant, a preservative, an emollient, a flavoring agent and a solvent, the moisturizing agent is selected from one or more of glycerol, polydimethylsiloxane, lecithin, ceramide EOP and sodium hyaluronate, and the emulsifier is selected from one or more of glycerol, polydimethylsiloxane, lecithin, ceramide EOP and sodium hyaluronate. The emulsifier is selected from one or more of stearic acid, cetyl alcohol and sorbitan oleate. The cream disclosed by the invention takes the sea cucumber peptide, the sophocarpidine and the inositol as active substances, and synergistically exerts the effects of moisturizing, relieving itching, relieving and repairing. The cream is uniform in cream body color, free of layering, fine and smooth in texture and free of sand grain feeling, and the cream preparation technology is suitable for large-scale industrial production.
Owner:BEIJING HOSPITAL

Ophthalmic topical cream preparation and its use

PendingJP2025524100ASenses disorderPeptide/protein ingredientsTopical creamAlkane
In this specification, C 7-20 A topical cream formulation comprising an alkane, a metal chelating agent and a buffer is described.
Owner:GLAUKOS CORP

Miconazole nitrate cream and process for its preparation

ActiveCN120131535BOrganic active ingredientsOrganic chemistryWhite petrolatumMicronazole
The application provides a miconazole nitrate cream and a preparation process, and belongs to the technical field of external medicines, and is characterized in that the miconazole nitrate cream comprises the following components in terms of mass fraction: 1.8wt-2.0wt% miconazole nitrate, 0.3wt-2.0wt% allantoin eugenol amide ester penetration enhancer, 3wt%-5wt% medium-chain triglyceride, 5wt%-10wt% glycerol monostearate, 8wt%-15wt% white petrolatum, 6wt-12wt% glycerol, 0.01wt%-0.10wt% bis(hydroxymethyl)imidazole alkyl urea, 6wt%-12wt% octadecanol, 1wt%-3wt% triethanolamine, and the balance is purified water. The preparation process comprises cream preparation, miconazole nitrate emulsion homogenization and miconazole nitrate cream preparation. The application prepares a nano miconazole nitrate cream product with uniform and delicate texture from the aspects of drug particle size optimization and homogenization. The added allantoin eugenol amide ester penetration enhancer is safe and non-irritating, and the use of the miconazole nitrate cream not only promotes the penetration of the cream and accelerates the recovery of the skin, but also has certain antioxidant function and can effectively prevent the cream from yellowing and deteriorating.
Owner:GUANGZHOU BAICAOTANG PHARMA

Method for simultaneously extracting panax japonicus saponin and polysaccharide, panax japonicus saponin polysaccharide extract, cream and cream preparation method

The invention discloses a method for simultaneously extracting panax japonicus saponin and polysaccharide, a panax japonicus saponin and polysaccharide extract, cream and a cream preparation method, and is characterized in that the extraction is performed according to the following method: adding panax japonicus powder into a solvent according to a material ratio of 1: 15, carrying out wall breaking treatment in a wall breaking machine for 30 seconds, then carrying out ultrasonic extraction at room temperature for 30 minutes under the ultrasonic power of 120 W, filtering, washing, and drying to obtain the panax japonicus saponin and polysaccharide extract. The solvent is an ethanol aqueous solution, and the volume concentration of ethanol in the ethanol aqueous solution is 15-75%. Or the panax japonicus powder is added into a solvent, the material ratio is 1: 15, ultrasonic extraction is carried out twice at the room temperature, each time is 30 min, the ultrasonic power is 120 W, the solvent is an ethanol aqueous solution, and the volume concentration of ethanol in the ethanol aqueous solution is 15%-75%. The extraction method is simple, saponin and polysaccharide can be extracted at the same time, the free radical scavenging rate of the extract reaches 96.4%, and the in-vitro antioxidant activity of the total extract is 1.36 times that of vitamin E. The anti-oxidation cream has obvious anti-oxidation capability and can be made into cream skin care products with an anti-oxidation effect.
Owner:CHONGQING MEDICAL & PHARMA COLLEGE

Highly concentrated dermally applicable permethrin preparation with an increased drug load in the target compartment for improved treatment of ectoparasite infestation

PCT designated stage expiredWO2025088039A1BiocideAerosol deliveryDiseaseHydrocotyle bowlesioides
The present invention relates to a semi-solid cream preparation for dermal-topical application in the event of / treatment of ectoparasites, the cream preparation comprising water, one or more hydrocarbon (lipid) components selected from nonpolar, in particular aliphatic, liquid, semi-solid and / or solid hydrocarbons (HC), one or more polar excipients having emulsifying properties (EMU), and the active substance permethrin (AS) in an amount of 8% to 13% by weight, the ratio of hydrocarbon component (HC) to active ingredient permethrin (AS) being 1.5 to 2.7. The application according to the invention also relates to the control of mites such as itch mites in humans, and the areas of the body affected, and in this respect the treatment of associated diseases such as scabies.
Owner:INFECTOPHARM ARZNEIMITTEL & CONSILIUM

Preparation and application of a nourishing and anti-wrinkle facial cream

ActiveCN118267339BCosmetic preparationsToilet preparationsBiotechnologyDextranomer hyaluronic acid
The present invention relates to the technical field of cosmetics, and in particular to the preparation and application of a nourishing and anti-wrinkle facial cream. The facial cream comprises active ingredients such as a Dendrobium officinale extract, a Dendrobium officinale yeast fermentation filtrate, an Opuntia radiata stem extract, panthenol, an Amygdalus dulcis seed extract, β-glucan, sodium hyaluronate, and carnosine. The facial cream of the present invention has excellent nourishing and anti-wrinkle properties; and a human patch test shows no obvious reddening, and is mild and non-irritating.
Owner:DOCTOR PLANT GUANGDONG BIOTECHNOLOGY CO LTD

Preparation device of plant nutrient-released amino acid facial cleanser

The utility model provides a device for preparing amino acid facial cleanser from plants. The preparation device comprises a tank body, a discharging pipe is installed at the bottom of the tank body, a valve part is installed outside the discharging pipe and used for controlling the discharging pipe to discharge facial cleanser, a feeding pipe, a stirring assembly and a side door assembly are installed at the top of the tank body, and the stirring assembly is connected with the side door assembly. The stirring assembly is connected with a mounting plate, the mounting plate is connected with a cleaning assembly, and the stirring assembly is used for stirring the facial cleanser in the tank body. According to the preparation device for the plant nutrient-released amino acid facial cleanser, under the interaction of components such as a limiting plate, a limiting groove, a limiting block, a torsional spring and a check block, the scraper can be quickly mounted on the mounting plate in the tank body or the scraper can be taken down from the mounting plate and taken out of the tank body when the scraper is not required to be used; and the scraping plate with residues is prevented from staying in the tank body to influence the preparation of the facial cleanser behind the tank body.
Owner:ZHONGYUAN MEIGU YILAN (LUOYANG) BIOTECHNOLOGY CO LTD +1