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59 results about "Miconazole Nitrate" patented technology
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The nitrate salt form of miconazole, an antifungal synthetic derivative of imidazole and used in the treatment of candidal skin infections, Miconazole selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes. (NCI04)
Microbial limit detection method of miconazole nitrate suppository
InactiveCN102586393AGood antibacterial effectPromote stratificationMicrobiological testing/measurementMicroorganism based processesFiltrationStaphyloccocus aureus
The invention discloses a microbial limit detection method of miconazole nitrate suppository. The method comprises dissolving sample with sodium chloride-peptone buffer solution (pH 7.0) containing 10 vol% polysorbate 80 (Tween 80), adding 20ml of isopropyl myristate, and washing with aqueous solution containing 0.1 vol% polysorbate 80 and 0.1 wt% peptone. Membrane filtration method is adopted for bacteria, mildew, yeast, Staphyloccocus aureus and Monilia albican, with recovery rate all above 70%. Culture medium dilution method is adopted to detect Pseudomonas Aeruginosa. The addition of isopropyl myristate can accelerate fat / water layer separation, shorten experiment time, stabilize flow rate, reduce test cost, and achieve strong operability.
Owner:SHAANXI INST FOR FOOD & DRUG CONTROL
Anti-infective hygiene products based on cellulose acetate phthalate
InactiveUS20070082035A1Hinders its propagationOrganic active ingredientsBiocideCellulose acetate phthalateCellulose acetate
Owner:NEW YORK BLOOD CENT
Medicinal composition for viganitis
InactiveCN1712003AAvoid side effects such as disordersOrganic active ingredientsEconazole NitrateTraditional medicine
A composite medicine for treating vaginitis is prepared from fossyol, econazole nitrate or miconazole nitrate, and medicinal auxiliary.
Owner:毛友昌
Antifungal medicine composition and its preparing method and use
ActiveCN1985883AEliminate side effectsImprove the problem of unstable curative effectAntimycoticsHydroxy compound active ingredientsAntifungalWestern medicine
The antifungal medicine composition is medicine prepared with the materials including snake oil 50-100 weight portions, Miconazole nitrate 25-50 weight portions, flavescent sophora root 20-50 weight portions, pearl powder 1-10 weight portions, menthol 1-5 weight portions, and borneol 1-5 weight portions. The antifungal medicine composition as one compound Chinese and Western medicine preparation contains effective antifungal components, and components for clearing away heat and toxic material, eliminating swelling, relieving pain, astringing and promoting granulation. It is used in treating tinea corporis, tinea cruris, tinea manuum, tinea pedis, etc caused by mycotic infection, and has stable treating effect and little side effect.
Owner:JIANGSU KANION PHARMA CO LTD
Nano-silver spray for treating skin diseases, and preparation method thereof
InactiveCN102198153AEasy to useSignificant effectOrganic active ingredientsAntimycoticsDiseaseSide effect
The invention discloses a nano-silver spray for treating skin diseases, and a preparation method thereof, aiming at providing a medicament prepared from nano-silver as a raw material for treating skin disease. The nano-silver spray comprises the following components in mass percent: 0.05-0.1% of nano-silver solution, 0.5-5% of miconazole nitrate, 0.5-1% of azone, 50-80% of alcohol, 0.01-0.05% of essence and purified water. The preparation method comprises the following steps of: adding the miconazole nitrate into a reaction kettle, then adding the alcohol, heating and stirring for reacting for 1-2 hours; adding the azone and the nano-silver solution, stirring for reacting for 1-2 hours; and adding the purified water and the essence, diluting and stirring for 0.5-1 hour, filtering and filling to obtain finished products. The nano-silver spray disclosed by the invention is applied to skin diseases such as tinea pedis, tinea manuum, tinea corporis, tinea cruris, psoriasis, dermatitis and the like, is especially suitable for patients with psoriasis inveterata, and has notable curative effects, convenience in use, safety and no side effects proven by clinical practice.
Owner:李平
Anti-inflammatory and antibacterial onychomycosis treating gel agent and preparation method thereof
ActiveCN107496792ARecovery functionSignificant effect on the treatment of onychomycosisAntimycoticsAerosol deliveryEthyl parabenInflammation
The invention provides an anti-inflammatory and antibacterial onychomycosis treating gel agent and a preparation method thereof. The gel agent contains the following substances: hydroxypropylmethyl cellulose, sodium carboxymethyl cellulose, glycerin, azone, miconazole nitrate, aloe oil, sea buckthorn fruit oil, white vinegar, a garlic extract, a sophora flavescens extract, a phryma leptostachya extract, a pepper extract, a stemona japonica extract, a folium artemisiae argyi extract, a kochia scoparia fruit extract, an impatiens balsamina extract, distilled water, ethanol with the concentration of 75%, urea, methylparaben and ethylparaben. Compared with the prior art, the gel agent provided by the invention has the advantages of quick absorption, good compliance, an exact effect of preventing and treating onychomycosis, efficacies of eliminating inflammation, resisting bacteria, improving the textures and colors of nails, treating beriberi and the like, and capabilities of significantly improving the onychomycosis of a patient and effectively improving the immunity.
Owner:WANNAN MEDICAL COLLEGE
Preparation method of miconazole nitrate
The invention discloses a preparation method of miconazole nitrate. The method comprises steps as follows: 2,4-dichloro-2'-chlorinated phenethyl alcohol, imidazole and 2,4-dichlorobenzyl are used as raw materials, an ionic liquid is used as a reaction medium, a reaction is conducted at the temperature 10-100 DEG C, a reaction liquid is cooled to the room temperature after the reaction is finished, the pH value of the reaction liquid is adjusted to range from 1 to 3 by the aid of a nitrate aqueous solution with the volume concentration of 15-50%, the reaction liquid is left to stand for layering, the lower layer is taken for recovery of the ionic liquid, the upper layer is taken for pressure reduced concentration until a solid is separated out, a concentrate is taken and cooled to the room temperature, then a recrystallization solvent is added to the concentrate for recrystallization, crystals are taken and dried, and the miconazole nitrate is obtained. According to the method, the ionic liquid is used as the reaction medium, and a one-pot reaction technology is combined; the method has the technical characteristics that the operation is simple and convenient, the reactions are safe, the yield is high, the ionic liquid can be reused continuously after a product is separated out, the method is environment-friendly and the like.
Owner:ZHEJIANG UNIV OF TECH
Miconazole nitrate expandable vaginal suppository, and preparation method and detection method thereof
ActiveCN103520086AGuaranteed effective concentrationPrevent outflowOrganic active ingredientsAntimycoticsSolubilityVaginal Suppository
Owner:哈尔滨田美药业股份有限公司
Compound miconazole nitrate emulsifiable paste and preparation technology thereof
InactiveCN109820860ASignificant effectPromote transdermal absorptionOrganic active ingredientsAntimycoticsTreatment effectGlycerol
The invention discloses a compound miconazole nitrate emulsifiable paste and a preparation technology thereof. According to the compound emulsifiable paste, miconazole nitrate and clobetasol propionate are adopted as main drug ingredients, a surface active agent and chondroitin sulfate are adopted as functional auxiliary additives, sodium alga acid is adopted as a thickening agent, glycerol is adopted as a lubricating moisture absorption agent, and on the basis of an absorption enhancer, the paste is prepared by grinding, smashing, vacuum mixing, vacuum stirring and refrigeration; the main drugs, the auxiliary additives and the enhancer are good in compatibility, and the external use treatment effect on tinea corporis, tine cruris, tine manuum, tine pedis, tinea versicolor, mycotic paronychia and monilial vaginitis caused by dermatophytes, saccharomycetes and other fungi is good.
Owner:JIANGSU YUANHENG PHARMA +1
Medicine composition for treating vaginitis and preparation method and application thereof
InactiveCN105535939AShort treatment timeGood treatment effectAntibacterial agentsOrganic active ingredientsCompound aFiltration
The invention discloses a medicine composition for treating vaginitis. The medicine composition is prepared from transdermal EGF and antibacterial drugs which serve as raw materials and carbomer and glycerol which serve as auxiliary materials. The invention further discloses a preparation method of the medicine composition. The preparation method comprises the following steps of preparing the raw materials and the auxiliary materials; compounding a solution matrix; dissolving nano-silver or miconazole nitrate in glycerol; adding triethanolamine to the matrix, and stirring the mixture slowly till the matrix becomes gel; conducting filtration and sterilization on the transdermal EGF; adding a transdermal EGF solution obtained after filtration to the gel matrix, adding deionized water, and conducting sub packaging. The medicine composition obtained through the method can be widely applied to externalia infection such as bacterial vaginitis and acroposthitis, restoration and healing of skin mucous membranes are accelerated in the inflammation treatment process, bacterial superinfection is prevented, and a certain auxiliary effect is achieved for vaginal contraction.
Owner:FUJIAN LONGSHENG BIOLOGICAL TECH CO LTD
Miconazole nitrate compound lotion and preparing method
InactiveCN105079405AOvercome the defects of simple sterilization and anti-inflammationEasy to useOrganic active ingredientsAntimycoticsAdditive ingredientTherapeutic effect
The invention discloses miconazole nitrate compound lotion and a preparing method. The lotion comprises miconazole nitrate, corydalis tuber, tricyrtis roots, radix sophorae flavescentis, wadalee-gum-tree, passiflora wilsonii, Jiu tou cao, cortex dictamni, polygonum multiflorum and folium artemisiae argyi. The preparing method includes the steps that materials are prepared, effective ingredients of traditional Chinese medicine are extracted, and the lotion is prepared. The miconazole nitrate compound lotion is a Chinese and western medicine mixture, effectively overcomes the defect that the miconazole nitrate only has the bactericidal anti-inflammatory function, is good in the synergistic effect of all medicine, directly acts on the infected part, high in the speed of taking effect, good in treatment effect and convenient to use. A method for conducting antisepsis and anti-inflammation, promoting granulation and draining toxin, removing pain, reliving itching and clearing away heat and toxic materials is adopted, manifestations and root causes of kysthitis are treated, the symptoms of pain and itching of a patient are relieved quickly, the vaginal secretion returns to normal, and the compliance of the patient is improved.
Owner:QINGDAO HAIZHIYUAN INTELLIGENT TECH
Nursing medicine liquid for treating burns and scalds and method for preparing nursing medicine liquid
InactiveCN105267676AEasy to applyShort course of treatmentHydroxy compound active ingredientsDermatological disorderChlorhexidine AcetateSide effect
The invention discloses nursing medicine liquid for treating burns and scalds and a method for preparing the nursing medicine liquid. The nursing medicine liquid comprises Chinese and western medicine components including, by weight, 50-80 parts of white sesame oil, 4-10 parts of nacre mother of pearl, 2-12 parts of lithospermum purpurocaeruleum, 2-9 parts of borneol, 5-10 parts of common bletilla pseudobulb, 10-15 parts of sanguisorba officinalis, 20-25 parts of rhubarb, 5-15 parts of angelica sinensis, 8-12 parts of radix sophorae subprostratae, 10-15 parts of rhizoma paridis, 15-20 parts of fructus cnidii, 5-10 parts of fructus kochiae, 12-15 parts of honeysuckle, 5-10 parts of white cinnamon, 5-8 parts of peppermint, 5-10 parts of radix ampelopsis, 5-8 parts of panax notoginseng, 5-8 parts of pearl powder, 0.3-0.5 part of honey, 0.1-0.2 part of chlorhexidine acetate, 0.1-0.2 part of miconazole nitrate, 0.2-0.5 part of amoxicillin, 0.1-0.2 part of cefalexin and 0.2-0.5 part of furazolidone powder. The nursing medicine liquid and the method have the advantages that the nursing medicine liquid can be easily and feasibly prepared and is low in cost; the nursing medicine liquid has few side effects and is inexpensive, and the burns and scalds can be effectively treated by the aid of the nursing medicine liquid.
Owner:鞠进英
Anti-infectious medical silicon rubber material and preparation method thereof
InactiveCN104927357AGood anti-infection effectStrong antibacterial functionHydrogen phosphatePolymer science
The invention discloses an anti-infectious medical silicon rubber material and a preparation method thereof. The anti-infectious medical silicon rubber material comprises the following components by mass: 56-73 parts of solid silicone rubber particles, 3-14 parts of butyl oleate, 11-19 parts of polyethylene wax, 2-8 parts of polyvinylpyrrolidone, 5-17 parts of miconazole nitrate, 13-24 parts of tridodecylamine, 5-22 parts of diammonium hydrogen phosphate, and 3-17 parts of an antioxygen. The silicon rubber material, prepared according to the preparation method, has an excellent antibacterial effect, can prevent infection, and has an important function in clinic treatment.
Owner:SUZHOU JONATHAN NEW MATERIALS TECH
A kind of gel containing antifungal drug and preparation method thereof
InactiveCN102258456AFully absorbedImprove bioavailabilityOrganic active ingredientsAntimycoticsAntifungal drugsRetention time
The invention relates to a gel containing antifungal drugs for treating fungal infections in different parts of the body and related skin ringworm and inflammation and a preparation method thereof. The gel is composed of 0.1%-20% by weight of fenticonazole nitrate, 0.1%-30% of polymer, 5%-95% of solvent, and 0%-30% of other pharmaceutically acceptable auxiliary materials . The gel agent of the present invention has the advantages of good visual effect, simple preparation process, convenient application, easy cleaning after use, full contact with the epidermis or mucous membrane of the drug administration site, long retention time, and the advantages of being convenient for fully exerting the drug effect and the like.
Owner:邹巧根
Production technology of miconazole nitrate vaginal tablets
InactiveCN110237042AIncrease profitImprove production efficiencyOrganic active ingredientsAntimycoticsPharmacyDry mixing
The invention provides a production technology of miconazole nitrate vaginal tablets, and relates to the technical field of a medicine making technology. The production technology of miconazole nitrate vaginal tablets comprises the following steps of performing weighing and blending, performing dry mixing to obtain wet granules, performing drying, performing granule trimming, performing total mixing, performing tabletting, performing packaging, and performing warehousing: performing packaging, performing total inspection, and performing warehousing. The miconazole nitrate vaginal tablets are produced through an assembly line of whole automated equipment, so that the making efficiency of the whole products can be improved, the yield of unit time can be increased, enterprise profits are increased, quality control is performed for products produced through multiple working procedures, the quality of products produced through a single working procedure can be guaranteed, control on the quality of finished products is realized, the content of defectives in the pharmacy process is reduced, and the whole rate of finished products in the whole pharmacy technological process is increased.
Owner:JINAN LIMIN PHARMA
External medicinal composition for treating dermatosis and preparation method for external medicinal composition
ActiveCN103520206AGood treatment effectOrganic active ingredientsDermatological disorderAllergic dermatitisContact dermatitis
The invention discloses an external medicinal composition for treating dermatosis. The external medicinal composition consists of the following components in percentage by weight: 5 to 12 percent of metronidazole powder, 1 to 4 percent of sulphur powder, 1 to 5 percent of camphor, 25 to 33 percent of clotrimazole cream, 26 to 35 percent of compound miconazole nitrate cream or compound ketoconazole cream and 20 to 40 percent of glycerine for medical purposes. A preparation process comprises the following steps of (1) adding the metronidazole powder, the sulphur powder and the camphor into the glycerine for medical purposes, heating the components to 80 to 100 DEG C, and uniformly mixing the components; (2) sequentially adding the clotrimazole cream and the compound miconazole nitrate cream or the compound ketoconazole cream after the components in the step (1) are cooled to room temperature, and completely and uniformly stirring the components to obtain the external medicinal composition. The external medicinal composition for treating dermatosis is prepared from a plurality of components with sterilization and antibacterial effects, has the effects of resisting fungi and anaerobic bacteria and killing mites, and has remarkable curative effects on allergic dermatitis, contact dermatitis and skin disorder caused by various germs.
Owner:陈嘉陵
Miconazole nitrate compound composition for gynecology department
InactiveCN109432110AHigh antibacterial activityGood antibacterial effectOrganic active ingredientsAntimycoticsPreservativeGynecology department
The invention relates to a miconazole nitrate compound composition for gynecology department. The compound composition is prepared from active ingredients of miconazole nitrate and pulchinenoside B4,and at least one auxiliary material used as a vaginal administration preparation, wherein the mass ratio of the miconazole nitrate to the pulchinenoside B4 in the composition is 1:(0.6 to 1.0); the composition can be prepared into a gel; the auxiliary material is selected from one or several kinds of materials from carbomer, humectants, preservatives, surfactants and pH regulators, and the balancewater.
Owner:天津凯茵科技有限公司
Miconazole nitrate compound vaginal extended-release effervescent tablets and preparation method thereof
InactiveCN105106561AMild and non-irritatingSmall side effectsOrganic active ingredientsAntimycoticsSodium bicarbonatePatient compliance
The invention discloses miconazole nitrate compound vaginal extended-release effervescent tablets and a preparation method thereof. The effervescent tablets comprise miconazole nitrate, Corydalis tuber, Tricyrtis root, lightyellow Sophora root, cutch, Wilson's passion flower, root of Silene tenuis, root-bark of shaggy-fruited dittany, fleeceflower root, Chinese mugwort leaf, sodium alginate, polyoxyethylene, fumaric acid, sodium carbonate, sodium bicarbonate, lauryl sodium sulfate, powdered sugar, and polysorbate. The preparation method includes: preparing materials, extracting effective ingredients of herbal materials, and performing granulating and tableting. The miconazole nitrate compound vaginal extended-release effervescent tablets are a Chinese and western medicine mixture, the defect that miconazole nitrate is only capable of killing germs and diminishing inflammation is effectively overcome, and the herbs are good in synergistic effect. Hydrophilic gel extended-release material is used as a medicinal auxiliary material, acting time of the tablets and administering interval can be prolonged, and bioavailability of the tablets can be improved; the tablets directly act on an affected part, take effect fast, are good in effect, are convenient to use and allow higher patient compliance.
Owner:QINGDAO HAIZHIYUAN INTELLIGENT TECH
Western medicine combined ointment for treating manus and tinea pedis and preparation method thereof
InactiveCN106492187AGood antibacterial effectAntipruriticAntimycoticsPeptide/protein ingredientsDexamethasone acetateGlycerol
The invention discloses western medicine combined ointment for treating manus and tinea pedis. The western medicine combined ointment is prepared from the following raw materials in parts by weight: 2 to 5 parts of miconazole nitrate cream, 2 to 5 parts of compound dexamethasone acetate cream, 5 to 10 parts of glycerol, 5 to 8 parts of marine fish oligopeptide, 0.2 to 0.5 part of vitamin E, 2 to 5 parts of loratadine, 2 to 5 parts of amprenavir, 0.01 to 0.05 part of anti-inflammatory preservatives, 1 to 3 parts of glycyrrhizic acid, 0.1 to 0.5 part of borneol, 0.5 to 2 parts of snake oil, 0.01 to 0.05 part of chondroitin sulfate, 1 to 2 parts of terbinafine hydrochloride solution and 10 to 20 parts of honey. The western medicine combined ointment achieves the synergic action through raw material compounding, and has the advantages that the bacteriostasis effect is good; the itching relieving and sterilization effects are achieved; the western medicine combined ointment can be used for effectively treating the manus and tinea pedis; the recurrence cannot easily occur; the medicine dependence is low; the treatment period is short; the thorough and radical cure can be realized; the western medicine combined ointment also has the curative effects of promoting blood circulation to remove blood stasis, relieving pain and inflammation and preventing infection.
Owner:ZHENGZHOU ZHENGXIAN PHARMA CO LTD
Western medicine ointment for treating tinea of feet and hands
InactiveCN106581636AGood antibacterial effectAntipruriticAntimycoticsHydroxy compound active ingredientsGlycerolAugmented Ointment
The invention discloses a western medicine ointment for treating tinea of feet and hands. The western medicine ointment is prepared from the following raw materials in parts by weight: 2-5 parts of miconazole nitrate cream, 2-5 parts of mometasone furoate gel, 5-10 parts of glycerol, 5-8 parts of ocean fish oligopeptides, 0.2-0.5 parts of vitamin E, 2-5 parts of Loratadine, 2-5 parts of Amprenavir, 0.01-0.05 parts of an anti-inflammation preservative, 1-3 parts of radix glycyrrhizae, 0.1-0.5 parts of flavones, 0.5-2 parts of snake oil, 0.01-0.05 parts of chondroitin sulfate, 1-2 parts of a terbinafine hydrochloride solution, and 10-20 parts of honey. The western medicine ointment achieves a synergistic effect by compounding the raw materials, has good effects of inhibiting bacteria, relieving itching and killing the bacteria, and can effectively treat the tinea of feet and hands; the western medicine ointment has the advantages of difficult relapse, low drug dependence, short treatment course and radical treatment; and the western medicine ointment also has the curative effects of activating blood to remove stasis, diminishing inflammation to relieve pain, and preventing infection.
Owner:ZHENGZHOU ZHENGXIAN PHARMA CO LTD
Compound miconazole nitrate composition for gynecology
ActiveCN109498621AGood treatment effectGood antibacterial effectOrganic active ingredientsAntimycoticsSuppositoryBULK ACTIVE INGREDIENT
The invention discloses a compound miconazole nitrate composition for gynecology. The compound miconazole nitrate composition is characterized by being prepared from active ingredients of miconazole nitrate and 23-hydroxy betulinic acid as well as at least one ingredient for vaginal administration preparation; the mass ratio of the miconazole nitrate to the 23-hydroxy betulinic acid in the composition is 1 to (0.3 to 0.5). The composition is prepared into gel or suppository.
Owner:THE AFFILIATED HOSPITAL OF QINGDAO UNIV
Miconazole nitrate compound vaginal effervescent tablets and preparation method thereof
InactiveCN105106560AMild and non-irritatingOvercome the defects of simple sterilization and anti-inflammationOrganic active ingredientsAntipyreticSodium bicarbonatePatient compliance
The invention discloses miconazole nitrate compound vaginal effervescent tablets and a preparation method thereof. The effervescent tablets comprise miconazole nitrate, Corydalis tuber, Tricyrtis root, lightyellow Sophora root, cutch, herb of Wilson Passionflower, radix Silene tenuis, root-bark of shaggy-fruited dittany, fleeceflower root, Chinese mugwort leaf, tartaric acid, sodium carbonate, sodium bicarbonate, lauryl sodium sulfate, dextrin, and polysorbate. The preparation method includes: preparing materials, extracting effective ingredients of herbal materials, and performing granulating and tableting. The miconazole nitrate compound vaginal effervescent tablets are a Chinese and western medicine mixture, the defect that miconazole nitrate is only capable of killing germs and diminishing inflammation is effectively overcome, and the herbs are good in synergistic effect. The tablets directly act on an affected part, take effect fast, are good in effect and are convenient to use; after the effervescent tablets effervesce, a larger contact area between medicine and the human body is provided; drug effect is improved. The tablets are capable of treating both symptoms and root causes of vaginitis, quickly relieving pain and pruritus symptoms of a patient, restoring vaginal secretion and improving patient compliance.
Owner:QINGDAO HAIZHIYUAN INTELLIGENT TECH
Antibacterial film-forming high-molecule liquid and preparation method thereof
ActiveCN108685886AImprove adhesionImprove efficiencyAntimycoticsInorganic active ingredientsCelluloseSodium Pyrithione
The invention provides antibacterial film-forming high-molecule liquid and a preparation method thereof. The antibacterial film-forming high-molecule liquid comprises solvents, high-molecule film-forming materials, antibacterial components, plasticizers, penetration enhancers and pH (potential of hydrogen) conditioning agents. The high-molecule film-forming materials are selected from one or moreof acrylic copolymers, Carbomer, polyvinyl alcohol, polyvinyl butyral, cellulose and chitosan derivatives. The antibacterial components are selected from one or more of chlorhexidine acetate, ZPT (zinc pyrithione), Casson, miconazole nitrate, terbinafine hydrochloride, Ketoconazole and amorolfine hydrochloride. Compared with traditional cream or baste, the antibacterial film-forming high-moleculeliquid is more convenient to use, antibacterial molecules do not easily lose when the liquid touches water or a user sweats after an affected part is coated with the antibacterial film-forming high-molecule liquid, and antibacterial effects are good.
Owner:武汉市贝斯特新材料有限责任公司
External medicine for treating skin diseases and preparation method thereof
InactiveCN102451180AHigh cure ratePromote healingOrganic active ingredientsAntimycoticsDiseaseCure rate
The invention discloses an external medicine for treating skin diseases, which contains coenzyme Q10 and miconazole nitrate as active components, wherein the coenzyme Q10 accounts for 0.01 to 79 percent of the weight of the external medicine, and the miconazole nitrate accounts for 0.01 to 45 percent of the weight of the external medicine. The invention also discloses a corresponding preparation method for the external medicine for treating skin diseases. The implementation of the invention can greatly increase the rate of curing various skin diseases, particularly, for the ringworm of the foot, the cure rate can reach more than 95 percent, and the recurrence rate is less than 10 percent in a year; and moreover, the external medicine also has an excellent effect in treating skin fester caused by burn, scald, cut and the like and promoting the healing of the skin fester.
Owner:马开龙 +1
Liquid gel and preparation method thereof
ActiveCN106266037ANo drug resistanceImprove the bactericidal effectAntibacterial agentsAntimycoticsSide effectTreatment effect
Provided are liquid gel and a preparation method thereof. The liquid gel is characterized in that the gel is prepared from 0.5-2.5 parts by weight of chitosan, 0.5-5 parts by weight of hydroxypropyl methylcellulose, 0.5-6 parts by weight of polyethylene glycol 6000, 0.1-0.3 part by weight of chlorhexidine acetate, 0.1-3 parts by weight of carbomer, 0.1-2 parts by weight of propylene glycol, 0.1-3 parts by weight of Chinese hawthorn seeds, 0.2-2 parts by weight of hyaluronic acid matter, 0.01-0.5 part by weight of miconazole nitrate and 50-70 parts by weight of purified water, and the pH ranges from 5 to 7.5. The liquid gel has the advantages of being small in side effect, good in treatment effect, not likely to cause genital tract flora unbalance and capable of effectively relieving or curing the disease.
Owner:吉安市御美丽健康产业股份有限公司
External medicinal composition for treating dermatosis and preparation method for external medicinal composition
ActiveCN103520206BGood treatment effectOrganic active ingredientsDermatological disorderAllergic dermatitisContact dermatitis
Owner:陈嘉陵
Metronidazole and miconazole nitrate compound vaginal effervescent tablet and method for preparing same
InactiveCN105106329AEasy to useNo drug dependenceOrganic active ingredientsAntimycoticsSodium bicarbonateAlysicarpus vaginalis
The invention discloses a metronidazole and miconazole nitrate compound vaginal effervescent tablet and a method for preparing the same. The effervescent tablet comprises metronidazole, miconazole nitrate, rhizoma corydalis, acacia catechu, Asian butteflybush roots and leaves, dicliptera chinensis, polygonum multiflorum, herba portulacae, alysicarpus vaginalis, prepared licorice, angelica dahurica, cicada slough, citric acid, sodium bicarbonate, potassium carbonate, polypropylene glycol 6000, dextrin, tween-80 and low-substituted hydroxypropyl cellulose. The method includes preparing materials; extracting effective components of crude traditional Chinese medicines; granulating the effective components; compressing the effective components to obtain the tablet. The metronidazole and miconazole nitrate compound vaginal effervescent tablet and the method have the advantages that the effervescent tablet is a Chinese-western medicine mixture, antibacterial / inhibition spectra can be broadened, shortcomings of pure western medicine and the shortcoming of inconvenience in carrying and storing washing liquor can be overcome, the metronidazole and miconazole nitrate compound vaginal effervescent tablet can directly act on affected parts of patients by the aid of a process for locally treating vaginitis in an external application manner, obvious synergistic effects can be realized by the medicines, the metronidazole and miconazole nitrate compound vaginal effervescent tablet can become effective fast, and good curative effects can be realized.
Owner:QINGDAO HAIZHIYUAN INTELLIGENT TECH
Miconazole nitrate vaginal expansion suppository and its preparation method and detection method
ActiveCN103520086BImprove accuracyGood reproducibilityOrganic active ingredientsAntimycoticsSolubilityVaginal Suppository
Owner:哈尔滨田美药业股份有限公司
Tinidazole/miconazole nitrate/neomycin self-microemulsion soft capsules for vagina and preparation method thereof
InactiveCN101703517BGuaranteed stabilityRapid lysisOrganic active ingredientsCapsule deliveryOil phaseIn vivo
The invention belongs to the field of medicinal preparations, and relates to self-microemulsion soft capsules containing tinidazole / miconazole nitrate / neomycin for vagina and a preparation method thereof. The self-microemulsion soft capsules for the vagina consist of tinidazole, miconazole nitrate and neomycin sulfate in treatment effective dose, and can be used for multiple vaginitis. The methodfor preparing the self-microemulsion soft capsules comprises the following steps: heating surfactant, co-surfactant and oil phase to melt, adding the tinidazole, the miconazole nitrate and the neomycin sulfate in prescription amount into the melted mixture, and stirring the mixture till dissolving to obtain the self-microemulsion soft capsules. The self-microemulsion soft capsules prepared by themethod improve the bioavailability of the medicament in vivo, have quick response, and overcome the defect that the common vaginal tablets have lower bioavailability; and meanwhile, serving as a new composite dosage form, the formulation is scientific and novel and can provide a newer and better dosage form selection for both doctors and patients. The preparation process is simple and has no special requirement on preparation environment, the cost is low, the product quality is stable, and the preparation method is suitable for industrialized production.
Owner:SHENYANG PHARMA UNIVERSITY
Externally-used medicine for treating stubborn ringworm and preparation method thereof
InactiveCN107441082AQuick killAnti-itchAntimycoticsHydroxy compound active ingredientsNitroimidazoleDexamethasone acetate
The invention discloses an externally-used medicine for treating stubborn ringworm and a preparation method thereof. The externally-used medicine comprises 2-3% of medicament and 97-98% of emulsifiable paste. The medicament comprises 2-methyl-5-nitroimidazole-1-ethanol, dexamethasone acetate, cyproheptadine hydrochloride, fluocinonide, miconazole nitrate, ketoconazole, clobetasol propionate, borneol and medical starch. Through scientific compatibility and mutual collaboration of the contents and proportions of all the components of the externally-used medicine for treating stubborn ringworm, the dosage is small, fungi can be quickly killed, itching is relived quickly, and stubborn ringworm is subjected to radical treatment; as for slight red and swollen symptoms cause by the fungi, itching is relived in the first day, the red and swollen symptoms disappear in the second day, and the color of the skin is changed; as for stubborn ringworm, such as psoriasis, existing for ages, the red and swollen symptoms are subsided within 3-5 days, after insistent applying for a month, reappearing of stubborn ringworm is avoided, and therefore radical treatment is achieved; and toxicity and irritation are small, dependence is avoided, the reappearing probability is small, the applicable range is wide, and the externally-used medicine can be used by pregnant women and children.
Owner:王昌华
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