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External medicine for treating skin diseases and preparation method thereof

A technology for external medicine and skin diseases, applied in the field of medicine, can solve the problems of no drugs, low actual cure rate of skin diseases, and difficulty in achieving a cure effect, etc., and achieves the effect of good healing and improved cure rate.

Inactive Publication Date: 2012-05-16
马开龙 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] But, the contriver finds in the process of implementing the present invention: take miconazole nitrate as main raw material and the actual cure rate of the dermatosis such as tinea pedis class is very low, and the patient is often trying to use miconazole nitrate etc. Conazole is the main raw material for external use and various other drugs for the treatment of skin diseases, but it is still difficult to achieve a curative effect, making it difficult for such patients to find effective cure drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0037] Add the dissolved coenzyme Q10 and miconazole nitrate solution and medicinal vaseline according to the weight of each of the following components dissolved in the homogenizer, and homogenize for 2 hours to obtain the external medicine (ointment) of the present invention Example 1:

[0038] Coenzyme Q10: 0.1g

[0039] Miconazole Nitrate 0.1g

[0040] Medicinal petroleum jelly 100g

example 2

[0042] Add the dissolved coenzyme Q10 and miconazole nitrate solution and medicinal vaseline according to the weight of each of the following components dissolved in the homogenizer, and homogenize for 2 hours to obtain the external medicine (ointment) of the present invention Example 2:

[0043] Coenzyme Q10: 2g

[0044] Miconazole Nitrate 2g

[0045] Medicinal Vaseline 96g

example 3

[0047] According to the weight after the dissolution of each of the following components, the dissolved coenzyme Q10 and miconazole nitrate solution and vaseline for medicine are added in the homogenizer, and after homogenization for 2 hours, the composition of the external medicine (ointment) of the present invention is obtained. Example 3.

[0048] Coenzyme Q10: 20g

[0049] Miconazole Nitrate 20g

[0050] Medicinal petroleum jelly 60g

[0051] Test method and dosage:

[0052] The external medicine (ointment) of the composition containing coenzyme Q10 prepared by the present invention for the treatment of dermatosis, gets appropriate amount and is applied to the diseased part of skin disease, and massages to make the ointment penetrate into the skin of the affected part, and the dosage is 2 to 5 ointments per day. Second-rate. After the symptoms of the diseased part disappear, you can continue to use it for 5 to 10 days to consolidate the effect of use.

[0053] The afo...

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PUM

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Abstract

The invention discloses an external medicine for treating skin diseases, which contains coenzyme Q10 and miconazole nitrate as active components, wherein the coenzyme Q10 accounts for 0.01 to 79 percent of the weight of the external medicine, and the miconazole nitrate accounts for 0.01 to 45 percent of the weight of the external medicine. The invention also discloses a corresponding preparation method for the external medicine for treating skin diseases. The implementation of the invention can greatly increase the rate of curing various skin diseases, particularly, for the ringworm of the foot, the cure rate can reach more than 95 percent, and the recurrence rate is less than 10 percent in a year; and moreover, the external medicine also has an excellent effect in treating skin fester caused by burn, scald, cut and the like and promoting the healing of the skin fester.

Description

technical field [0001] The invention relates to the field of medicine, in particular to an external medicine for treating skin diseases, especially tinea pedis and a preparation method thereof. Background technique [0002] Coenzyme Q10 is a fat-soluble quinone compound widely present in the human body. It plays an important role in proton translocation and electron transfer in the respiratory chain in the human body. It is an activator of cell respiration and cell metabolism, and is also an important antioxidant and non-specific immune enhancer. Coenzyme Q10 is mainly used in the auxiliary treatment of diseases such as heart disease and hepatitis. [0003] Patent document 08109347.7 discloses the use of coenzyme Q10 as a skin preparation, and points out that oxidized coenzyme Q10 can produce excellent therapeutic effects on atopic dermatitis. However, the inventor found in the process of implementing the present invention that after many clinical trials, the composition c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4174A61K31/122A61P17/00A61P17/02A61P31/10
Inventor 马开龙厉庚乐
Owner 马开龙
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