186 results about "Skin preparation" patented technology

Disclosed are a stretchable microneedle adhesive patch (SNAP) capable of performing high-quality electrophysiological (EP) signal measurement without skin preparation, such as exfoliating the skin or removing sweat, a SNAP system, and an operating method thereof. The disclosed SNAP capable of performing skin preparation-free high-quality EP signal measurement includes an electrically conductive adhesive (ECA) layer configured to attach to a user's skin to obtain an EP signal regardless of the user's skin condition; a microneedle sensor including a microneedle array configured to penetrate the stratum corneum by passing through the ECA layer and to directly contact the skin epidermis of the user; and conductive wire-based stretchable interconnects having a serpentine structure that is electrically and mechanically connected to the microneedle sensor to dynamically adapt to skin deformation of the user.

To provide a topical skin preparation that effectively promotes collagen production within the skin, exhibits excellent usability, and effectively enhances post-use stratum corneum moisture content.SOLUTION: A topical skin preparation comprises niacinamide, a heparin-like substance, dipotassium glycyrrhizinate, a collagen peptide, a yeast extract, and glycylglycine. It is preferable that the topical skin preparation further contains hydrogenated soybean phospholipids and phytosterols. It is more preferable that the topical skin preparation has a niacinamide content of 5 mass% or more. It is also preferable that the topical skin preparation further contains at least one plant extract selected from Arnica montana and Plantago major.SELECTED DRAWING: Figure 1

The invention provides a conformal skin preparation process key parameter optimization and rapid prediction database construction method, equipment and a medium. According to the method, key characteristics such as global temperature distribution, curing degree distribution, internal stress distribution, resin / fiber volume distribution and surface displacement distribution are calculated through a multi-physics field intensity coupling simulation model under different process parameter conditions, and the curing deformation mechanism in the conformal skin curing process is disclosed. Different curing process conditions are determined to cover various possible operating conditions. And for each working condition, numerical simulation of the curing process is carried out, and data such as temperature distribution, curing degree distribution, internal stress distribution, resin / fiber volume distribution and surface displacement distribution under each working condition are recorded. Simulation results under different working conditions are systematically stored in a database, and a multi-working-condition simulation database is obtained. Based on the constructed database, the process can be effectively optimized, the product quality is improved, and the technology development is promoted.

The invention belongs to the technical field of cosmetics, and discloses a plant extract with instant and long-acting whitening and relieving anti-inflammatory effects as well as a preparation method and application thereof. The plant extract comprises a liquorice extract, a tea leaf extract, a scutellaria baicalensis root extract and a mulberry root bark extract; the plant extract is prepared from licorice roots, tea leaves, radix scutellariae roots and mulberry root barks according to the mass ratio of (1-5): (1-5): (1-3): (1-3), various plant extracts are compounded, a semi-bionic method is adopted for assisting a deep-eutectic solvent for extraction, all the components play a synergistic effect, the whitening and skin care effects and the efficient soothing and anti-inflammatory effects can be achieved, and the plant extract is free of toxic and side effects. The traditional Chinese medicine composition has the advantages that the traditional Chinese medicine composition takes effect quickly, is strong in instantaneity, can whiten skin for a long time, has certain acne-removing and oil-controlling effects, has diversified effects and safe, reliable and effective components, can be applied to preparation of skin care products or skin preparations, and is very suitable for being used by crowds of 18-30 years old.

This invention belongs to the field of cosmetic technology and discloses a plant extract with immediate and long-lasting whitening, soothing, and anti-inflammatory effects, as well as its preparation method and application. The plant extract includes licorice extract, tea extract, scutellaria root extract, and mulberry root bark extract. Using licorice, tea, scutellaria root, and mulberry root bark in a mass ratio of 1-5:1-5:1-3:1-3 as raw materials, the extract is obtained by compounding multiple plant extracts and using a semi-bionic method with an assisted eutectic solvent for extraction. This allows the components to exert a synergistic effect, achieving whitening and skin care while also providing highly effective soothing and anti-inflammatory effects. It is fast-acting, has strong immediate effects, and provides long-lasting whitening. It also has certain acne-reducing and oil-controlling effects, offering diverse efficacy. The ingredients are safe, reliable, and effective, and can be applied to the preparation of skin care products or skin preparations. It is very suitable for people aged 18-30.

The invention provides a cosmetic application of nervonic acid. The cosmetic application is selected from the group consisting of anti-saccharification, energy metabolism, DNA damage repair, soothing and / or repair efficacy. The invention also relates to application of nervonic acid in preparation of an external skin preparation with anti-saccharification, energy metabolism, DNA damage repair, soothing and / or repair effects.

The object of the present invention is to provide a novel ascorbic acid derivative with excellent stability, and its applications. [Solution] A compound (compound of general formula (1) below) is used, in which a phosphocholine group is introduced to the hydroxyl group at the 2 position of ascorbic acid via a phosphate ester bond. The ascorbic acid derivative of the present invention has excellent whitening and antioxidant properties, and is also highly stable. Therefore, the ascorbic acid derivative of the present invention can be preferably used as an active ingredient in cosmetics and topical skin preparations. TIFF2026055124000012.tif39101

The present invention provides topical and internal skin preparations containing an extract of soapwort cultivated under artificial light with a specific wavelength range. [Solution] The soapwort of the present invention is cultivated by irradiating it with artificial light having a specific wavelength range, and the extract exhibits excellent collagen production promoting effect, MMP inhibitory effect, hyaluronic acid production promoting effect, cell proliferation promoting effect, and antioxidant effect. Furthermore, topical or internal skin preparations containing these effects are particularly effective and also exhibit excellent safety and stability. The soapwort extract of the present invention can be used not only in the field of beauty, such as preventing skin aging, but also in the field of medicine, such as suppressing functional decline due to aging, and is expected to be applied to cosmetics, foods, quasi-drugs, and pharmaceuticals.

The electric hair removing knife comprises a shell, a hair removing motor is fixed in the shell, the outer side wall of an output shaft of the hair removing motor is connected with a movable cylinder in a sliding mode, a spring is fixed at the left end of the output shaft of the hair removing motor, and the movable cylinder is connected with the movable cylinder in a sliding mode. And the other end of the spring is fixedly connected with the left side of the interior of the moving cylinder, a hair removing tool bit is arranged on the outer side of the moving cylinder, and two blocking strips are fixed to the outer side wall of the moving cylinder. According to the electric hair removal knife suitable for preoperative skin preparation, by arranging an adsorption motor, a round pipe, fan blades and air outlet holes, the adsorption motor is started to drive the fan blades to rotate, and the fan blades rotate to exhaust air in the round holes through the air outlet holes, so that negative pressure is generated in the round holes, and hair suction holes suck broken hair removed by a knife head; the broken wool enters the round pipe and then enters the collecting bin, so that the collection of the removed broken wool is completed, and the round pipe can prevent the broken wool from leaking downwards.

The present application relates to the field of model construction, in particular to a kind of construction method of vertebral artery compression rat model, the inner diameter and blood flow velocity of normal rat vertebral artery are obtained by ultrasonic detection;Anesthetize rat, skin preparation, disinfection, incision, expose vertebral artery;According to the required compression degree, select the tissue clip of corresponding specification, fix on vertebral artery, keep vertebral artery in compression state;Suture incision, disinfection, bandage;After rat awakens, daily care, feed, until incision healing;Ultrasonic detection is carried out, the inner diameter and blood flow velocity of the vertebral artery of rat model are obtained, compared with the inner diameter and blood flow velocity of the vertebral artery of the same age healthy rat or rat before modeling, whether it meets the standard of successful modeling is judged.

To develop a novel plant extract having an excellent skin-conditioning effect.SOLUTION: Provided are a caspase-14 activator or an anti-oxidizing agent containing a Japanese apricot extract, and an external preparation for skin containing the caspase-14 activator or the anti-oxidizing agent.EFFECT OF THE INVENTION: According to the present invention, skin is protected from dryness, ultraviolet light and active oxygen which are harmful to skin by increasing the enzymatic activity of caspase-14 and deleting active oxygen, and a skin-conditioning effect that the external preparation for skin should include can be realized.SELECTED DRAWING: Figure 1

The invention belongs to the technical field of medical instruments, and discloses a head operation skin preparation device which comprises an electric shaver, a razor is fixedly mounted at the end of the electric shaver, and an adsorption head located over the razor is fixedly connected to the outer surface of the electric shaver. By arranging the adsorption head, the connecting hose, the movable pipe, the air suction pipe and the fan, after the electric shaver is started, a medical worker holds the electric shaver by hand to be attached to the head of a patient, hair in an operation area is accurately shaved with the help of a shaver, the fan is synchronously started to construct a negative pressure adsorption passage, and under the continuous negative pressure acting force, the electric shaver is driven to rotate. The adsorption head, the connecting hose, the movable pipe and the air suction pipe are cooperatively matched to capture shaved broken hair in real time, the hair is attached to the plate face after being filtered and intercepted by the filter screen plate, purified air is smoothly discharged through the exhaust pipe, the situation that the shaved hair drifts around to pollute the operation environment is avoided from the source, and the risk that the hair falls into a wound to cause infection is avoided.

The invention provides a compound Chinese blister beetle capsule traditional Chinese medicine composition as well as a preparation method and a detection method thereof, and belongs to the field of traditional Chinese medicine preparation, the compound Chinese blister beetle capsule traditional Chinese medicine composition as well as the preparation method and the detection method thereof comprise the specific steps of medicinal material preparation, medicinal material cleaning, medicinal material treatment, capsule preparation, capsule sampling and chromatographic monitoring. The reasonable preparation technology is provided, the qualified rate of the prepared capsules can be increased, medicinal material cleaning work is carried out through the step 2 in the preparation process, impurities on the surfaces of medicinal materials are prevented from influencing the quality of the prepared capsules, meanwhile, in cooperation with the step 4, the capsule skin cleaning work is carried out in the capsule preparation process, and the quality of the prepared capsules is improved. Impurities generated during capsule skin preparation are prevented from being mixed into medicinal materials to influence the quality of the medicinal materials; meanwhile, the capsule detection effect is improved.

The application relates to the technical field of basketball preparation, and discloses a rubber basketball outer skin preparation device, which comprises a bottom plate, a rubber forming bin is connected to one side of the top end of the bottom plate, a feeding guide plate is connected to one side of the inner wall of the rubber forming bin, a primary forming mechanism and a transfer conveying unit are connected between the two sides of the inner wall of the rubber forming bin, a heat insulation cover is connected to one side of the inner wall of the rubber forming bin, an electric heating wire is connected to one side of the inner wall of the heat insulation cover, a secondary forming mechanism is connected to one side of the inner wall of the rubber forming bin, a guide roller is rotationally arranged on one side of the inner wall of the rubber forming bin, a connecting frame is connected to one side of the rubber forming bin, a discharging conveying unit is connected to one side of the connecting frame which is close to each other, and a cooling frame is connected to the top end of the connecting frame. The application effectively reduces the preparation procedures, reduces the production cost, guarantees the processing effect, effectively improves the preparation efficiency of the basketball outer skin, and reduces the labor consumption.

To provide a kit for obtaining a foaming topical skin preparation that improves skin condition and has a pleasant feel. [Solution] The present invention provides a kit for obtaining a foaming topical skin preparation, which is obtained by mixing an acidic substance, a carbon dioxide generating substance that reacts with the acidic substance to generate carbon dioxide, a thickener, and water, and is characterized by the incorporation of two or more thickeners in combination.

The utility model relates to the field of medical skin preparation knives, in particular to a disposable medical armpit skin preparation knife. Comprising a hollow spherical tool bit attached to the armpit curve, a plurality of rows of arc-shaped blades matched with the tool bit in outline are installed on the outer surface of the tool bit, and a plurality of liquid outlet holes are formed between the blades. The cutter head and the cutter handle with the cavity are integrally formed; a piston push rod is arranged in the cutter handle; and the arc-shaped blade faces downwards and forms a certain inclined angle with the tangent line of the hollow spherical cutter head. The shaver is simple in structure and convenient to use, the blade can go deep into the armpit, hair difficult to touch is better removed, and the shaver handle comprises the bent section, so that the convenience during shaving operation is improved. The design of the spherical cutter head accords with the armpit physiological curvature of a human body, and the infection risk of an operative incision can be reduced.

This invention relates to a whitening extract from geranium, its preparation method, and its application, belonging to the field of plant extract preparation and cosmetic technology. The extraction method includes: preparing a eutectic solvent by mixing choline chloride and citric acid in a molar ratio of 2:1 to 4:1, and adjusting the water content to 30-70%; mixing geranium raw material powder with the eutectic solvent at a material-liquid ratio of 1:5-15 (g / mL), and performing ultrasonic-assisted extraction; concentrating the extract under reduced pressure and then freeze-drying to obtain a geranium whitening extract with a total flavonoid content of 1-4 mg / g, a total polyphenol content of 3-6 mg / g, and anthocyanin content of 1-3 mg / g. This extract can be used to prepare cosmetics or topical skin preparations with whitening, brightening, antioxidant, or pigmentation-improving effects, as well as a tyrosinase activity inhibitor. This invention provides a green and efficient method for extracting the whitening active ingredients from geranium.

To provide an azelaic acid derivative capable of inhibiting stimulation of skin by a skin external preparation applied thereto.SOLUTION: The azelaic acid derivative is represented by AO-C(=O)-R-C(=O)-OA (formula 1) or BO-C(=O)-R-C(=O)-OA (formula 2). The skin external preparation contains active agents, oil-based agents and water-based agents, where the azelaic acid derivative is contained as an oil-based agent. In the formulas 1 and 2, R is a C7 linear hydrocarbon group, A is represented by the general formula CnH2n+1, CnH2n+1O or CnH2n+1O2 comprising a hydrocarbon group, and B is hydrogen or the general formula CnH2n+1, CnH2n+1O or CnH2n+1O2 comprising a hydrocarbon group.SELECTED DRAWING: None

This invention relates to the field of medical device technology, specifically to a multifunctional medical skin preparation knife, comprising a gripping part and a blade head, the blade head containing a blade; a moving cavity is formed within the gripping part, and a piston rod is slidably fitted within the moving cavity; the side of the blade head away from the gripping part is spherical, and a power component is fixedly connected to one end of the gripping part near the blade head, the output shaft of the power component being coaxially and detachably connected to a central block, the central block having several slots for clamping the blade; a processing cavity is formed within the blade head, the central block being located within the processing cavity, and several contact grooves are formed on the surface of the blade head, the contact grooves communicating with the processing cavity; an air exchange mechanism for suction or pumping air is provided between the processing cavity and the moving cavity; this invention reduces the difficulty of cleaning hair in recessed and wrinkled areas and the generation of hair residue, while also reducing the risk of infection and medical costs through the detachable blade head structure.

The present invention addresses the problem of providing an external preparation for skin having improved stability in an external preparation for skin containing a heparin analogue and at least one substance selected from the group consisting of loxoprofen, salts thereof, and hydrates thereof. The present invention provides an external preparation for the skin, which contains a heparin analogue and at least one substance selected from the group consisting of loxoprofen, salts thereof, and hydrates thereof, and which has excellent stability.

A skin preparation device (7) for preparing a region of skin (8) ready for delivering a therapeutic or cosmetic substance into the body of a subject through the skin or for measuring the concentration of a substance that is extracted from the region of skin, the device comprising an array of microneedles arranged to form artificial pores in the skin. The length and sharpness of the microneedles is limited to minimise trauma to the skin to minimise an inflammatory response. A plurality of micro-protrusions (5) may extend from an apex (1) of each microneedle or the tip of each microneedle may be bent to form a single, lateral micro-protrusion (6).

To provide a topical skin preparation with improved stability in which a solid or semisolid oil solution is blended in a transparent or translucent soluble system.SOLUTION: A translucent or transparent topical skin preparation contains (A) a solid or semisolid oil solution, (B) an oil solution of hydrocarbons that is liquid at normal temperature, (C) polyoxyethylenated (1-40 E.O.) and polyoxypropylenated (1-30 P.O.) alkyl (C16-C24), (D) a C18-22 higher alcohol, (E) a polyhydric alcohol, and (F) water.SELECTED DRAWING: None

The invention relates to a skin preparation, in particular to a preparation method and application of plant compound essential oil. The plant compound essential oil is prepared from calendula officinalis infused oil, rose hip oil, sesame oil, fennelflower oil, lemon verbena oil, pelargonium graveolens oil, Damascus rose oil, clary sage oil, wormwood oil, chaste tree oil, European red pine oil and other raw materials, and the obtained compound essential oil is excellent in performance and has a good use effect.

The utility model discloses a skin preparation knife with a lubricating function, which comprises a knife head and a knife handle, the knife head is detachably connected with the lower end of the knife handle, the knife handle comprises an upper handle and a lower handle, the upper handle is in threaded connection with the lower handle, a storage part for storing lubricating liquid is arranged in the lower handle, and a driving part for pushing and extruding the lubricating liquid is arranged in the upper handle. A guide column used for guiding lubricating liquid is arranged at the joint of the tool bit and the tool handle and attached to the lower end of the storage part. The scalpel has the advantages that the scalpel handle is divided into the upper handle and the lower handle, the liquid storage cavity used for storing lubricating liquid is arranged in the lower handle, the push rod used for pushing and extruding the lubricating liquid is arranged in the upper handle, the blade and the skin of a patient can be lubricated conveniently, and operation is easy and convenient; meanwhile, the lubricating liquid flows through the cutting edge of the blade after being guided and drips at the operation position, the blade can be lubricated, the skin of a patient can also be lubricated, and the pain feeling during skin preparation is reduced.

The utility model relates to a disposable electric skin preparation device, which solves the problem that the existing electric skin preparation device cannot meet the requirement of disposable use and quick replacement of a cutter head, and comprises a shell, a cutter head and a cutter head driving mechanism, the cutter head comprises a cutter head shell, a blade supporting plate, a blade driving plate and a blade, and the cutter head driving mechanism comprises a motor and an eccentric wheel. The motor drives the blade driving plate and the blade to move back and forth in the direction perpendicular to the blade teeth, the electric skin preparation device further comprises a locking piece used for locking the tool bit shell and the outer shell, and during disassembly, when the locking piece is opened and the tool bit outer shell is pulled out, a push plate on the tool bit outer shell pushes a clamping table on the blade driving plate to enable the blade driving plate to be separated from the eccentric wheel shaft. When the disposable tool bit is installed, the eccentric wheel shaft is connected with the oblong hole in the blade driving plate of a new tool bit in an inserted mode, the tool bit shell and the outer shell are locked through the locking piece, and therefore the tool bit is disposable, rapid to replace and convenient to use, all parts making contact with hair are replaced, and use is sanitary and safe.

The invention relates to the technical field of medical instruments, in particular to ophthalmology clip type skin preparation scissors which comprise a first grab handle and a second grab handle which are rotatably connected through a connecting part. The cutting tool further comprises a fixed clamping part and a movable clamping part, a second blade is connected to the fixed clamping part in a sliding mode, a first blade is connected to the movable clamping part in a sliding mode, and the first blade and the second blade are oppositely arranged to form a cutting edge; when the first grab handle and the second grab handle are operated, the movable clamping part can move relative to the fixed clamping part to clamp eyelashes, and after the eyelashes are clamped in place, the first blade and the second blade move relatively to complete eyelash shearing. Clamping and shearing actions are integrated in a single tool, the movable clamping part and the fixed clamping part can be synchronously driven to clamp eyelashes, meanwhile, the first blade and the second blade are driven to move relatively to complete shearing, the problem that the eyelashes are prone to shifting or not completely sheared in a traditional tool is solved, and the eyelashes can be conveniently sheared. The high-efficiency requirement of skin preparation before ophthalmologic operation is met.

This invention discloses a PDRN ginsenoside system and its preparation method, belonging to the field of cosmetics and topical skin preparations. Addressing the shortcomings of existing skincare products containing PDRN and ginsenosides, such as easy inactivation of active ingredients, low co-encapsulation rate of the two components, poor transdermal absorption efficiency, insufficient system stability and compatibility, and lack of synergistic effects, this invention designs a ginsenoside system composed of a phase A lipid carrier, a phase B aqueous matrix, and a phase C functional adjuvant. The proportions of each component are optimized, and a corresponding preparation process is provided. This invention achieves efficient co-loading of water-soluble PDRN and lipid-soluble ginsenosides, improving system stability and transdermal bioavailability of active ingredients, while also providing synergistic repair and anti-aging effects. It is gentle and non-irritating, and the preparation process is suitable for large-scale industrial production, making it widely applicable in various skincare formulations.

An applicator device configured for delivery of at least one solution to a surface, includes an applicator body having a head portion including an opening, a distal end, and an outer wall forming an interior space, and a fluid container moveably positioned in the interior space of the applicator body, the fluid container having an interior portion for holding the at least one solution and a membrane for preventing passage of the solution out of the interior portion. The device further includes a piercing element configured to breach the membrane to allow for passage of the solution out of the interior space of the fluid container, and a distal cap coupled to the distal end of the applicator body configured such that rotation of the distal cap causes longitudinal movement of the fluid container within the interior space of the applicator body into contact with the piercing element.

To provide a topical skin preparation containing loxoprofen and 60% by mass or more of lower alcohol based on the total amount of the topical skin preparation, with improved storage stability. [Solution] A topical skin preparation containing loxoprofen or a salt thereof, and one or more pH adjusting agents selected from hydrochloric acid or malic acid and their salts, at a concentration of 60% by mass or more based on the total amount of the topical skin preparation.

The present invention relates to a high-viscosity or solid topical skin composition having a skin-protective function. A technology has been developed to manufacture a formulation with a texture having high viscosity without using wax or surfactants by utilizing a high-viscosity mixture composed of an ammonium salt and an ammonium salt solvent. When a UV blocking material or an antioxidant material is mixed into this and used as a topical skin preparation, an effect of alleviating light-induced skin damage can be obtained without clogging pores or irritation.