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Solution formulations of sirolimus and its analogs for CAD treatment

Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.
Owner:WYETH LLC

Fault comprehensive processing platform and method of distribution network

The invention relates to a fault comprehensive processing platform and method of a distribution network, belonging to the technical field of power grid management. The fault comprehensive processing platform comprises a fault information acquisition system, a fault information judgment system and a fault repair power failure information pushing system. The fault comprehensive processing method comprises the steps of: acquiring information of repair faults, line faults and consumption faults in a distribution automatic management system and a power utilization information acquisition system, receiving and checking the information; carrying out equipment location, fault information screening, line topology analysis, equipment operation information analysis and line switch analysis; determining fault types, places and affected regions and showing in the traditional GIS (Geographic Information System); and guiding fault repair according to a determined fault result, and pushing fault power failure information and power supply recovering information to a user. The platform and the method realize concentrated acquisition and automatic pre-judgment on the traditional fault information, can also be used for actively pushing power failure and power supply recovering information to the user, and interact with the user.
Owner:JIANGSU ELECTRIC POWER CO +2
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