80 results about "Topical skin agent" patented technology

To provide a composition for external use on the skin for reducing skin wrinkles containing polyvinyl alcohol, and more particularly, a composition excellent in reducing skin wrinkles by sustainably contracting the skin only by drying after application to the skin without a separate film, by containing a high molecular weight polyvinyl alcohol.SOLUTION: The composition according to the present disclosure can reduce skin wrinkles without side effects and at a lower cost compared to conventional wrinkle-improving treatments.SELECTED DRAWING: Figure 1

The invention discloses a composition for improving the stability of 4-butylresorcinol, application of the composition and an external skin preparation, and belongs to the technical field of cosmetics. The composition is prepared from the following components in parts by weight: 0.01 to 5 parts of 4-butyl resorcinol, 0.005 to 0.195 part of sodium pyrosulfite, 0.005 to 0.195 part of sodium hydrogen sulfite, 0.005 to 3 parts of ergothioneine and 0.003 to 0.2 part of troxerutin. The composition can maintain the 4-butylresorcinol not to change color for a long time, and especially can maintain the original color under the conditions of ultraviolet irradiation and light irradiation for 3 months. The composition is used for preparing the external skin preparation, so that the external skin preparation also has better color stability, and the product quality of the external skin preparation is improved.

To provide a topical skin preparation that effectively promotes collagen production within the skin, exhibits excellent usability, and effectively enhances post-use stratum corneum moisture content.SOLUTION: A topical skin preparation comprises niacinamide, a heparin-like substance, dipotassium glycyrrhizinate, a collagen peptide, a yeast extract, and glycylglycine. It is preferable that the topical skin preparation further contains hydrogenated soybean phospholipids and phytosterols. It is more preferable that the topical skin preparation has a niacinamide content of 5 mass% or more. It is also preferable that the topical skin preparation further contains at least one plant extract selected from Arnica montana and Plantago major.SELECTED DRAWING: Figure 1

To provide an external preparation for skin containing a plant-derived lactic acid bacterium and a specified plant extract.SOLUTION: An external preparation for skin comprises bacterial cells of Lactobacillus casei subsp. casei strain 327 and a specified plant extract.SELECTED DRAWING: None

The invention provides a novel fungus strain Inonotus obliquus HHKJ415 with the preservation number of CGMCC (China General Microbiological Culture Collection Center) No.41664, and further provides an Inonotus obliquus fermentation-poria cocos extract for relieving retinoic acid stimulation, a preparation method of the Inonotus obliquus fermentation-poria cocos extract and an application of the Inonotus obliquus fermentation-poria cocos extract in the aspect of preparing a skin external preparation. The preparation method comprises the following steps: inoculating a fermentation substrate with an inonotus obliquus HHKJ415 bacterial solution for fermentation; the fermentation substrate is prepared from poria cocos powder, potato glucose water powder and water in a mass ratio of (0.8-1.5): (2.0-3.0): 10; and sterilizing and separating the fermentation product to obtain the inonotus obliquus-poria cocos fermentation supernatant and mycelium. The inonotus obliquus HHKJ415 is inoculated to a culture medium added with poria cocos and potato glucose water to be fermented to obtain mycelium, and the mycelium is subjected to hot water extraction to obtain an active matter which is safe and non-irritant, has good antioxidant and anti-inflammatory effects and can relieve retinoic acid stimulation.

To provide a topical skin agent which exhibits a synergistically enhanced moisturizing effect through the combined use of specific components.SOLUTION: The present invention provides a topical skin agent comprising the following components (A) to (C): (A) bakuchiol, (B) glyceryl glucoside, and (C) one or more selected from rice fermentation liquid, niacinamide, and hydrolyzed collagen.SELECTED DRAWING: None

This invention provides novel stem cell activators, topical skin agents containing the aforementioned stem cell activators, and skin cosmetics containing the aforementioned stem cell activators. The stem cell activator of this invention comprises at least one compound selected from compounds (including optically active agents) shown in formula (1), salts of the aforementioned compounds, and hydrates thereof as active ingredients. In the following formula, R... 1 R 2 Represents a hydrogen atom or a hydrocarbon group. R 3 Represents a hydrogen atom or an organic group. n represents an integer greater than or equal to 1. The above hydrocarbon groups may have substituents. [Chemical Formula 1]

To develop a novel plant extract having an excellent skin-conditioning effect.SOLUTION: Provided are a caspase-14 activator or an anti-oxidizing agent containing a Japanese apricot extract, and an external preparation for skin containing the caspase-14 activator or the anti-oxidizing agent.EFFECT OF THE INVENTION: According to the present invention, skin is protected from dryness, ultraviolet light and active oxygen which are harmful to skin by increasing the enzymatic activity of caspase-14 and deleting active oxygen, and a skin-conditioning effect that the external preparation for skin should include can be realized.SELECTED DRAWING: Figure 1

To provide a kit for obtaining a foaming topical skin preparation that improves skin condition and has a pleasant feel. [Solution] The present invention provides a kit for obtaining a foaming topical skin preparation, which is obtained by mixing an acidic substance, a carbon dioxide generating substance that reacts with the acidic substance to generate carbon dioxide, a thickener, and water, and is characterized by the incorporation of two or more thickeners in combination.

The present invention relates to a topical dermatological composition for improving the skin, comprising exosomes derived from callus of Lithospermum erythrorhizon S., which has excellent properties including cell proliferation promotion, wound healing promotion, anti-inflammation, collagen synthesis promotion, and whitening effects, and may provide a topical dermatological composition for improving the skin having excellent cell inflow characteristics of exosomes, thereby significantly improving the skin physiological activity effects.

To provide a topical skin preparation containing loxoprofen and 60% by mass or more of lower alcohol based on the total amount of the topical skin preparation, with improved storage stability. [Solution] A topical skin preparation containing loxoprofen or a salt thereof, and one or more pH adjusting agents selected from hydrochloric acid or malic acid and their salts, at a concentration of 60% by mass or more based on the total amount of the topical skin preparation.

The present invention relates to a high-viscosity or solid topical skin composition having a skin-protective function. A technology has been developed to manufacture a formulation with a texture having high viscosity without using wax or surfactants by utilizing a high-viscosity mixture composed of an ammonium salt and an ammonium salt solvent. When a UV blocking material or an antioxidant material is mixed into this and used as a topical skin preparation, an effect of alleviating light-induced skin damage can be obtained without clogging pores or irritation.

To provide a new combination of active ingredients capable of being incorporated into a topical preparation for skin, activating epidermal cells, enhancing energy metabolism of epidermal cells, normalizing skin turnover, improving skin texture, and enhancing skin translucency.SOLUTION: A topical preparation for skin comprises, as active ingredients, (a) niacinamide and (b) D-panthenyl alcohol.SELECTED DRAWING: None

According to one embodiment, a melanin production inhibitor comprising a compound represented by formula (I) or a salt thereof is provided: [In formula (I), R represents an alkyl group having 1 to 4 carbon atoms].

The present application relates to a preservative comprising caprylic hydroxamic acid, 4′-hydroxyacetophenone, and a polyol for an externally-applied skin preparation, and use thereof, and a preservative for an externally-applied skin preparation according to an aspect exhibits excellent anti-bacterial or anti-septic effect effects against bacteria and fungi. In particular, even though it includes 4′-hydroxyacetophenone and caprylyl glycol as active ingredients, a preservative for an externally-applied skin preparation according to an aspect does not show a deterioration in anti-bacterial or anti-septic effects against bacteria and fungi and maintains significantly excellent anti-bacterial or anti-septic effects, when applied to a cosmetic composition including a surfactant. Therefore, a preservative for an externally-applied skin preparation according to an aspect may be advantageously used for anti-bacterial, preservative, or anti-septic treatment of various cosmetic compositions, including cleaning products, or externally-applied skin preparations.

To provide a topical preparation for skin that exhibits moisture retention and allows reduction of stickiness.SOLUTION: A topical preparation for skin comprises (A) an aloe extract and (B) a polysaccharide, where the polysaccharide (B) includes a structural unit represented by a specific formula.SELECTED DRAWING: None

The present invention relates to a dermatological composition for external application, containing, as an active ingredient, a complex ingredient comprising betulin, a ceramide, a soybean extract, and a green tea seed extract. The dermatological composition for external application has the effects of improving the skin barrier by activating keratinocyte proliferation, enhancing the moisture retention of the skin by reducing transepidermal water loss, and improving acne by inhibiting the lipase activity of Cutibacterium acnes.

This invention provides the application of a cyclic dipeptide in inhibiting the TRPV1 protein, wherein the cyclic dipeptide is a cyclic (D-leucine-L-proline) dipeptide. This invention also relates to the application of the cyclic dipeptide in the preparation of topical skin agents or pharmaceuticals with TRPV1 protein inhibitory activity, wherein the topical skin agent is selected from: creams, lotions, gels, toners, serums, masks, eye creams, aerosol cleansing foams, sprays, shower gels, or facial cleansers.

The present invention provides a collagen production promoter and a topical skin preparation containing the same. [Solution] According to one embodiment, a collagen production promoter comprising a compound represented by formula (I) or a salt thereof is provided: TIFF2026087505000015.tif31163 [In formula (I), R represents an alkyl group having 1 to 4 carbon atoms.]

To provide a topical skin preparation that has excellent effects in preventing and improving wrinkles, anti-aging, anti-inflammatory, pore tightening, whitening, and improving firmness and elasticity, while reducing skin stickiness and being easily absorbed by the skin. [Solution] A topical skin preparation containing specific plant materials, niacin, and glycyrrhizic acid.

The present invention relates to: a cosmetic composition and topical preparation for skin containing an oat ferment filtrate and having skin whitening, elasticity and pore improvement, skin inflammation relief, and hair improvement activities; and use thereof. In particular, the present invention is characterized by a ferment filtrate produced by a proprietary oat koji production with full koji infiltration and multi-stage continuous fermentation method, and uses a composite fermentation technique that combines main fermentation and post-fermentation unlike conventional single fermentation methods. The cosmetic composition of the present invention was proven to be highly effective in skin moisturization, whitening, wrinkle improvement, pore reduction, and the like in clinical trials, and in particular, exhibited greater improvement in all evaluated areas compared to existing fermented cosmetics.

The invention provides a composition containing plant seed grease and a preparation method thereof. The plant seed oil is selected from simmondsia chinensis seed oil, safflower seed oil, meadowfoam seed oil, sunflower seed oil, macadamia nut seed oil, castor seed oil, peony seed oil, grape seed oil, grapefruit seed oil, apple seed oil, pomegranate seed oil, watermelon seed oil, zucchini seed oil, linseed oil, rapeseed oil, sesame seed oil and the like or a combination thereof. Based on the total weight of the composition, the composition comprises at least 0.5 wt% of plant seed grease. The invention also relates to an application of the composition containing the plant seed grease in enhancing the skin barrier function and / or in preparing a medicine for enhancing the skin barrier function and / or an external preparation for the skin.

This skin barrier function improving agent contains cytidylic acid or a precursor thereof as an active ingredient.

To provide a topical skin composition that has moderate viscosity while exhibiting excellent stability over time. [Solution] A composition for topical use on the skin, comprising the following components (A) to (F): (A) a polyglycerin fatty acid ester in which R in the fatty acid-derived group R-COO- is an alkyl group having 13 to 23 carbon atoms or an alkenyl group having 13 to 23 carbon atoms; (B) a polyhydric alcohol of trivalent or higher; (C) a polyhydric alcohol of divalent value; (D) an oily component that is liquid at 25°C; (E) a compound represented by formula (I), its salts and mixtures thereof; and (F) a nonionic surfactant other than component (A) and component (E) with an HLB of 4.5 to 12.0, and substantially free of water.

It suppresses the expression of matrix metalloproteinase 1. [Solution] The disclosed matrix metalloproteinase 1 expression inhibitor contains as an active ingredient at least one selected from the group consisting of Saxifraga stolonifera, Saxifraga stolonifera extract, Rosemary, Rosemary extract, Licorice, Licorice extract, Melissa, Melissa extract, Wild thyme, Wild thyme extract, Hops, and Hops extract.

To provide a composition that enables simple preparation of liposomes having positively charged surfaces without raising safety concerns when used in cosmetics or topical skin preparations.SOLUTION: The present invention provides a composition for preparing liposomes having positively charged surfaces, the composition containing the following components (A) and (B), with the content of component (A) being 1 to 30 mass% and the content of component (B) being 70 to 99 mass%. The inventive composition for preparing liposomes enables simple preparation of liposomes having positively charged surfaces through dispersion in water. Component (A) is a liposome membrane component containing the following components (A1) and (A2): (A1) phospholipid; and (A2) sphingosine compound. Component (B) is a polyhydric alcohol.SELECTED DRAWING: None

The objective is to provide an active ingredient for topical skin preparations or food and beverages that is derived from natural products, has excellent biocompatibility and stability, and further possesses excellent skin penetration and metabolic properties. [Solution] A topical skin preparation or food / beverage containing a fish scale extract solution or a fermented product of fish scales by microorganisms as an active ingredient, characterized in that the microorganisms have protease activity or aminopeptidase activity.

To provide a novel agent for regulating skin-resident microbiota, not being limited in use form to topical skin agents and enabling adjustment of the balance of skin resident microbiota in other forms.SOLUTION: Provided is an agent comprising essential oil and / or extract of tea tree.SELECTED DRAWING: Figure 1

The present invention relates to an oil-in-water type topical skin agent composition which uses a gel of crosslinked hyaluronic acid or its salt, thereby having a special texture and feel like ice cream, and the composition of the present invention contains gel particles and emulsified particles of crosslinked hyaluronic acid or its salt with a D(0.5) of particle size distribution in a specific range in the aqueous phase and the oil phase respectively, so that the composition has a granular feel like ice cream, mashed potatoes or meringue, and also has a soft appearance and texture, can provide a refreshing feel when applied, and is easy to clean because the outer phase is an aqueous phase.

To provide a skin external preparation containing hydrolyzed gardenia extract that allows suppression of discoloration of the hydrolyzed gardenia extract and enables application to a broad range of formulations.SOLUTION: A skin external preparation contains (A) hydrolyzed gardenia extract and (B) nicotinamide. By containing (A) hydrolyzed gardenia extract and (B) nicotinamide, the skin external preparation prevents discoloration of the hydrolyzed gardenia extract while enabling application to a broad range of formulations.SELECTED DRAWING: None