103 results about "Hydrolyzed collagen" patented technology

This invention provides an anti-aging and repairing composition containing collagen and its preparation method, belonging to the technical field of medical, dental, or cosmetic products. Its components consist of hydrolyzed collagen, recombinant type III human collagen, artichoke leaf extract, and fermented blueberry seed oil. This invention uses recombinant type III human collagen and hydrolyzed collagen as its core, overcoming the limitations of traditional collagen through biotechnology, and supplementing it with double-fermented plant ingredients to solve the bottlenecks of transdermal absorption and anti-oxidation. The overall design conforms to the anti-aging triangle logic of "repair, defense, and moisturizing," and has good market prospects.

The invention discloses an Ectoin and hydrolyzed collagen silanol composition as well as a preparation method and application thereof. The preparation method comprises the following steps: preparing a hydrolyzed collagen silanol derivative: hydrolyzing a silane coupling agent in an acidic organic solvent aqueous solution to obtain silanol hydrolysate; the preparation method comprises the following steps: dissolving hydrolyzed collagen in deionized water, adjusting the pH value to 8-10, stirring, adding silanol hydrolysate for reaction, cooling to room temperature, and freeze-drying to obtain hydrolyzed collagen silanol derivative powder; the preparation method comprises the following steps: preparing an Ectoine and hydrolyzed collagen silanol composition: dissolving hydrolyzed collagen silanol derivative powder and Ectoine in pure water together, and carrying out ultrasonic treatment to obtain the Ectoine and hydrolyzed collagen silanol composition, the prepared composition can inhibit skin heat injury, inhibit skin inflammatory response, promote skin collagen regeneration and repair skin barrier, and can be applied as a raw material of skin care products or medical beauty products.

A composition is provided that includes hydrolyzed collagen, at least one biguanide, at least one vicinal diol, and at least one chelating agent. The composition exhibits at least 2-log reduction of planktonic microbes within 24 hours. Methods of using the composition are also provided.

The invention discloses a fish hydrolyzed collagen peptide-based flavor beverage and a preparation method thereof, and relates to the technical field of food beverages. The flavored beverage comprises the following raw materials: fish hydrolyzed collagen peptide, a compound flavor modification stabilizer, a compound sweetening agent, concentrated fruit and vegetable juice, casein phosphopeptides, VC magnesium phosphate, zinc lactate, a low-nucleic-acid yeast extract, sodium hyaluronate, an acidity regulator and purified water. The compound flavor modification stabilizer is matched with the low nucleic acid yeast extract to form synergistic flavor regulation and control, the hydrophobic bitter peptide fragment of the fish hydrolyzed collagen peptide and the fishy smell characteristic group are wrapped from the molecular level, and meanwhile, the soft modification on the sensory level is realized through the gamma-aminobutyric acid; the effect of debitterizing and deodorizing without adding artificial essence and a large amount of cane sugar is achieved, the product flavor is natural and harmonious, the sour and sweet taste is palatable, the beverage completely conforms to the current healthy consumption trend of low sugar and no artificial addition, and the problem that the beverage has flavor defects is solved.

The present application relates to the technical field of health care products, in particular to a pelvic floor muscle repairing composition containing supermolecular tightening Dropsordry and a preparation method thereof, which comprises the following components in mass fraction: 10-14 parts of protein composition, 20-24 parts of chitosan modified Dropsordry, 5-7 parts of freeze-dried powder of Lactobacillus bulgaricus, 10-12 parts of hyaluronic acid, 6-8 parts of glycine and 15-17 parts of proline; each part of the protein composition comprises 20-30 parts of myosin, 30-34 parts of actin, 5-10 parts of hydrolyzed collagen and 240-280 parts of deionized water. The pelvic floor muscle repairing composition can reduce drug toxicity, reduce the amount of drug administration, continuously supplement the required elements of the body during treatment, and quickly relieve the constipation problem caused by the functional damage of the pelvic floor muscle.

The object of the present invention is to provide a non-invasive agent that, in particular, exhibits a skin-improving effect and reduces the visible signs of aging. For this purpose, the invention provides a liquid oral composition as a food supplement or dietary food, comprising liquid marine hydrolyzed collagen peptides obtained from cod skin.

Provided in the present application are a gel composition containing a hydrolyzed collagen and use thereof. The gel composition comprises a collagen peptide, a hydrolyzed collagen, and a sugar alcohol. According to the mass ratio, hydrolyzed collagen:sugar alcohol = 4-12:3-94. The number of hydroxyl groups in sugar alcohol repeating units is not less than 3. The molecular weight of the collagen peptide is 500-10000 Da. The molecular weight of the hydrolyzed collagen is 10000-20000 Da. In the gel composition, according to the mass ratio, hydrolyzed collagen:collagen peptide = 4-12:2-25.

The present invention relates to a pharmaceutical composition and method for treating skin conditions. The composition comprises a hydrogel film containing an effective amount of at least one active ingredient selected from hydrolyzed collagen, sodium hyaluronate, aloe barbadensis leaf extract, tocopheryl acetate, and rosa rugosa flower oil, along with one or more gelling agents capable of forming a co-polymer network. The hydrogel film is configured to adhere to the skin and deliver the active ingredient in a targeted and prolonged manner. The method involves applying the film to an affected area of the skin for a period sufficient to treat conditions such as sunburn, dryness, and eczema. The invention provides a convenient and effective means of delivering active ingredients directly to the skin while maintaining the structural integrity of the film during use.

The present invention relates to a method for producing a collagen peptide preparation containing recombinant collagen peptides. The method is characterized in that it comprises the following steps: a) providing an in vitro expression system including at least one expression cassette, the expression cassette including at least one nucleotide sequence encoding a collagen peptide having a molecular weight in the range of 8 to 100 kDa; b) incubating the expression system under conditions that allow expression of the collagen peptide; c) obtaining the collagen peptide; d) hydrolyzing the collagen peptide under conditions that result in the production of a collagen peptide preparation including collagen peptides having an average molecular weight of 1 to 5 kDa and a molecular weight in the range of 0.1 to 12 kDa; wherein no more than 5.5% by weight of the hydrolyzed collagen peptides have a molecular weight of less than 500 Da, no more than 2.8% by weight of the hydrolyzed collagen peptides have a molecular weight between 7500 Da and 13500 Da, and between 35% and 60% by weight of the hydrolyzed collagen peptides have a molecular weight between 1500 Da and 3500 Da; e) obtain the collagen peptide preparation.

The invention discloses novel efficient nourishing leather oil and a preparation method thereof. The novel efficient nourishing leather oil is prepared from a natural vegetable oil matrix, hydrolyzed collagen, nano silicon dioxide aerogel, a vegetable wax compound, an antioxidant system and a bioactive penetrant. The preparation method adopts a low-temperature gradient mixing and high-pressure homogenizing process to realize stable dispersion of active components. Tests show that the penetration depth of the product reaches 2.3 times that of a traditional product, the wear resistance is improved by 40%, the biodegradation rate is larger than 90%, and the product is suitable for long-acting maintenance of high-grade leatherware.

The invention discloses a method for improving the binding force of an electrolytic copper foil and a base material under low roughness and the electrolytic copper foil. The method comprises the following steps: 1) carrying out smooth acid pickling on a 9-35 [mu] m raw foil; (2) performing picosecond laser selective ablation on bulges of more than 100nm on the surface of the pickled raw foil to enable Ra to be less than or equal to 0.1 mu m; (3) depositing a compact copper layer of 0.1-0.4 mu m to fill the micro pits; 4) coarsening in a coarsening solution containing copper ions, sulfuric acid, sodium tungstate and sodium molybdate; 5) curing in a curing liquid containing copper ions, sulfuric acid, MPS, HEC, PEG and hydrolyzed collagen; (6) heat-resisting treatment and passivating treatment are conducted in sequence; 7) spraying an organic silane coupling agent; and (8) drying at 130-140 DEG C for 5-10 seconds, and then rolling at the speed of 4-6 m / min. According to the method, the formation of a high-roughness structure is avoided through laser leveling, the compact copper layer reinforces the substrate to improve the uniformity of copper nodules, the lamination surface Rz of a final product is smaller than or equal to 1.5 microns, Ra is smaller than or equal to 0.2 microns, the peel strength is larger than or equal to 0.7 N / mm, no copper powder falls off during lamination, and the method is suitable for preparing the high-precision copper foil.

The invention relates to an anti-aging composition, a firming and glowing essence containing the anti-aging composition and a preparation method of the firming and glowing essence. The anti-aging composition is prepared from the following components in parts by weight: 1.5 to 6 parts of glyceryl polyether-26, 1.5 to 5 parts of nicotinamide, 0.25 to 1.2 parts of xylitol, 0.13 to 0.3 part of sodium hyaluronate, 0.01 to 0.3 part of carnosine, 0.01 to 0.1 part of PCA sodium, 0.005 to 0.05 part of hydrolyzed collagen, 0.006 to 0.03 part of palmitoyl tripeptide-5, 0.0008 to 0.01 part of hexapeptide-9 and 0.001 to 0.01 part of dipeptide diaminobutyryl benzyl amide diacetate. Test results show that the tightening and glowing essence developed by adopting the composition has the effects of instantly supplementing moisture for skin, promoting collagen generation, improving wrinkles and helping the skin to recover a supporting structure so as to slow down aging, and has a good market prospect.

The invention provides a freeze-drying composition capable of improving skin feeling as well as a preparation method and application of the freeze-drying composition. The freeze-drying composition comprises hydrolyzed collagen, sodium polyacrylate, sodium alginate and functional components, the functional component comprises any one or a combination of at least two of madecassoside, pentapeptide-48 or oat beta-glucan. The hydrolyzed collagen, the sodium polyacrylate and the sodium alginate in the freeze-dried composition disclosed by the invention are synergistically matched, so that the stability of a product and the use skin feeling of the product can be improved, and the activity of functional components is improved.

To provide a liquid skin detergent composition having high moisturizing power to the skin after towel drying.SOLUTION: (A) at least one selected from the group consisting of hydrolyzed collagen and hydrolyzed silk.SELECTED DRAWING: None

Hydrolyzed collagen compositions are described which are used for treatment of impaired cartilage or to prevent damage to healthy cartilage. These compositions function across multiple cartilage components and structures. Oral, topical, or cartilage-site delivery of the compositions to cartilage may be via liquid, gel, powder, or sheet form. Additionally, the hydrolyzed collagen composition may be applied as a coating on a medical device.

The invention relates to collagenase as well as a coding gene and application thereof. The collagenase provided by the invention is a protein (a) or (b), wherein (a) is a protein composed of an amino acid sequence as shown in SEQ ID No: 1; and (b) a protein which is obtained by substituting, deleting or adding one or more amino acids in the amino acid sequence in (a), has collagen hydrolysis or fat dissolving activity and is derived from (a). The collagenase provided by the invention can be applied to cell separation and tissue digestion, fat dissolution or collagen dissolution, and can also be applied to preparation of medicines for treating Doltt's contracture, Petroleum disease and lumbar disc herniation and degreasing in the field of beauty.

The invention provides an anti-aging repairing composition containing collagen and a preparation method of the anti-aging repairing composition, and belongs to the technical field of medical, dental or dressing preparations. The collagen composition is composed of hydrolyzed collagen, recombinant III-type human collagen, cynara scolymus leaf extract and fermented bilberry seed oil. Recombinant III-type human collagen and hydrolyzed collagen are taken as cores, the limitation of traditional collagen is broken through through a biotechnology, the bottleneck of transdermal penetration and oxidation resistance is solved with the assistance of double-fermentation plant components, and the overall design conforms to the anti-aging triangular logic of'repairing, defending and moisturizing '; good market prospects are realized.

The invention provides an acidic decolorizing agent. The invention relates to an adhesive which comprises the following components in parts by weight: 30-34 parts of hydrolyzed wheat starch, 28-32 parts of wheat flour, 12-16 parts of potassium persulfate, 4-8 parts of ammonium persulfate, 3.5-7.5 parts of hydroxyethyl cellulose, 1.5-5.5 parts of silicon dioxide, 1-2 parts of hydroxypropyl trimethyl ammonium chloride hydrolyzed collagen, 0.8-1.3 parts of guar gum and 0.8-1.3 parts of sodium metasilicate. The invention relates to an anti-rust agent, which is prepared from the following components in parts by weight: 0.8 to 1.3 parts of magnesium stearate, 0.8 to 1.3 parts of magnesium carbonate, 0.8 to 1.3 parts of disodium ethylene diamine tetraacetate, 0.08 to 0.12 part of hydrolyzed keratin, 0.4 to 0.8 part of sodium laureth sulfate, 0.3 to 0.5 part of titanium dioxide, 0.3 to 0.5 part of glucose and 0.1 to 0.3 part of mineral oil.

A hydrolyzed collagen-based composition comprising hydrolyzed collagen and 0.01 to 50 wt% of polylysine based on the percent solids of the hydrolyzed collagen-based composition is provided. Methods of treating tissue (e.g., impaired tissue) are also provided.

The invention relates to the technical field of wash supplies, in particular to a volcanic mud-containing composition with color fixing and locking effects and a preparation method of the volcanic mud-containing composition. The composition prepared by the invention is widely applicable to damaged, coarse or ironed and dyed hair, not only can solve the problem that the hair color is easy to change, but also can improve the problem of frizzy and dry hair, and realizes the combination of color holding and hair care, so that the hair color is lasting and beautiful, and the hair is easier to care. Specifically, through combined use of the hydroxyferriheme, the volcanic mud, the myrtle wood oil and the hydroxyethyl ethylenediamine triacetic acid, the obvious color fixing and locking effects can be jointly achieved from multiple aspects of delaying fading, reducing pigment molecule escape and enhancing light aging protection and color fixing; besides, hydrolyzed conchiolin protein, hydroxypropyl trimethyl ammonium chloride hydrolyzed collagen and behentrimethylammonium chloride are combined for use, so that the hair conditioner can be progressive layer by layer from the three layers of internal repair, charge neutralization and external lubrication, the hair combing resistance is jointly reduced, and the smoothness and combing property of the hair are improved.

According to the composition, hydrolyzed collagen, soluble collagen and elastin serve as core repairing components, active components such as a bifidus yeast fermentation product lysate, rosa damascena flower water and a centella asiatica extract are compounded, and auxiliary components such as 1, 2-hexanediol are matched, so that the collagen repairing composition is prepared. And a synergistic effect is realized through scientific proportioning. The composition disclosed by the invention can be quickly absorbed by skin, effectively replenishes skin moisture, locks moisture, improves skin dryness, cares skin barrier and makes skin soft, moist and glossy; the preparation method is simple in process, high in stability and suitable for industrial production.

A hydrolyzed collagen-based composition is provided. The composition includes 25 wt % to 99.9995 wt % of hydrolyzed collagen; and 0.0005 wt % to 50 wt % of an antibiotic component, wherein the percentages are based on the percent solids of the composition. Methods of using the composition are also provided.

The embodiment of the invention provides anti-hair-loss, plump and dense hair essence, and relates to the field of hair care essence. The essence is prepared from water, ethyl alcohol, butanediol, PPG-26-butanol polyether-26, PEG-40 hydrogenated castor oil, tetrahydromethylpyrimidine carboxylic acid, 1, 2-hexanediol, caprylyl glycol, a ginseng root extract, palmitoyl tetrapeptide-7, a cacumen biotae extract, 1, 2-hexanediol, 1, 3-pentanediol, 1, 3-pentanediol, 1, 3-pentanediol, 1, 3-pentanediol, 1, 3-pentanediol and the like. The preparation method comprises the following steps: adding 1, 3-propylene glycol, phenoxyethanol, p-hydroxyacetophenone, carbomer, triethanolamine, adenosine, hydrolyzed sodium hyaluronate, hydrolyzed collagen, hydrolyzed elastin, caramel color, a scutellaria baicalensis root extract, a ginger root extract, copper tripeptide-1, a chamomilla recutita flower extract, glycerin, polysorbate-20, lactic acid, ethylhexylglycerin, carnosine, acetyl hexapeptide-8, palmitoyl pentapeptide-4, 2, 4-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1 The composition is prepared from the following raw materials: palmitoyl tripeptide-1, rosemary leaf extract, acetyl hexapeptide-8, arginine / lysine polypeptide, acetyl tetrapeptide-2 and acetyl tetrapeptide-5.

The invention provides an emulsion for removing eye wrinkles and a preparation method thereof.According to the emulsion, core raw materials such as hydrolyzed collagen, multiple active polypeptides, glaine and retinol are matched according to the specific mass percent, moisturizing and repairing components and permeation promoting and relieving components are matched, and a full-link wrinkle removing system is formed; the preparation process adopts the processes of whole-course light shielding, gradient cooling step-by-step loading and low-temperature nano homogenization, so that the activity of active ingredients is effectively reserved, and the transdermal absorption rate is improved. In-vitro cell experiments and human body trial verification show that the emulsion can significantly promote collagen regeneration and inhibit expression of aging-related factors, is mild and non-irritant, can effectively improve dynamic lines, static lines and dry lines around eyes, and solves the problems of single effect, strong irritation and low activity utilization rate of existing products.

The invention relates to the technical field of cosmetics, in particular to a brightening and firming mask which comprises mask base cloth and essence, and the essence is composed of functional components and the balance of matrix. Wherein the functional components comprise fine euglena polysaccharide, hydrolyzed collagen, tranexamic acid, hydroxyethyl piperazine ethanesulfonic acid, glutathione and copper peptide. According to the mask provided by the invention, firstly, the euglena gracilis polysaccharide and the hydrolyzed collagen are used for rapidly and synergistically tightening and smoothing the skin from the aspect of physical tightening, and meanwhile, the hydrolyzed collagen can stay in the deep part of the epidermal layer for a long time to promote the synthesis of the collagen so as to bring an endogenous skin tightening effect; then tranexamic acid, glutathione and copper peptide are compounded according to a specific proportion and have a synergistic effect, the activity of tyrosinase is inhibited, and then cutin is mildly stripped through hydroxyethyl piperazine ethanesulfonic acid, so that the functional components rapidly whiten and brighten the skin.

A Pharmaceutical composition for treating bacterial skin infections, burns and wounds is disclosed. It comprises an active ingredient, preferably Mupirocin, a biopolymer, preferably Chitosan, with molecular weight ranging from 250,000 Da to 600,000 Da, and a degree of deacetylation of not less than 80%, hydrolyzed Collagen, preferably of type I, with molecular weight ranging from 3 kDa to 6 kDa, and an ointment base comprising emulsifying agents, glycols and solubilizers. The invention has improved stability than the existing ointments, it heals skin and re-epithelializes faster than existing treatments thereby reducing hospitalisation period.

The invention provides a composition capable of tightening vagina and recovering elasticity and a preparation method thereof, and the composition comprises the following components in parts by mass: 75-130 parts of a collagen structure repairing unit, 25-55 parts of a composite cross-linking agent, 8-35 parts of a fibroblast activating factor and 12-38 parts of a plant tannin delivery body. The problem of membrane permeation is solved through high-activity hydrolyzed collagen peptide, a difunctional cross-linking system is formed by chemical grafting of dermatan sulfate and carboxymethyl beta-glucan, the fibroblast activation efficiency is enhanced by means of a zinc ion mediated polypeptide complexing structure, and the bottleneck in the prior art is remarkably broken through on key indexes.

The invention discloses a special diet for improving cardiovascular and cerebrovascular diseases and microcirculation disturbance and a preparation method thereof, and the special diet comprises the following components in parts by weight: 2-4 parts of bone collagen peptide, 1-2 parts of taurine, 2-3 parts of hydrolyzed collagen peptide, 1-2 parts of marine fish oligopeptide, 1-2 parts of inulin, 1-2 parts of erythritol, 2-3 parts of acerola cherry fruit powder and 2-3 parts of guarana extract. 1-2 parts of N-acetylneuraminic acid, 1-2 parts of vitamin C, 1-2 parts of vitamin B6, 1-2 parts of vitamin B1 and 1-2 parts of vitamin B2; the traditional Chinese medicine composition can improve cardiovascular functions and microcirculation disturbance, and has remarkable effects in the aspects of inhibiting cardiovascular diseases, promoting microcirculation and enhancing immunity.

A PEGylated composition including a PEGylated protein-containing microgel and a hydrolyzed collagen component is provided. The PEGylated protein-containing microgel includes a protein component crosslinked by a PEGylating component. Methods of making the PEGylated composition, and methods of treatment using the PEGylated composition are also provided.

The present invention relates to the technical field of fibronectin preparations, and particularly discloses a fibronectin preparation, which comprises 1-5 mg / ml of hydrolyzed collagen, 0.5-5 mg / ml of pullulan, and 0.4 mg / ml of a fibronectin stock solution. The pullulan and the hydrolyzed collagen are added into the fibronectin stock solution, the pullulan and the hydrolyzed collagen play a synergistic role, and a protective net is constructed through a barrier and a hydration layer, so that denaturation of the fibronectin can be reduced, and turbidity or precipitation formed by protein agglomeration can be avoided; the stability, the biocompatibility and the effect of the fibronectin preparation are obviously improved.