608 results about "Hydrolyzed collagen" patented technology

The composition and method for healing tissues is a medicinal composition for facilitating the growth, protection and healing of tissues and cells in animals and humans. The composition is formulated as a either a powder, gel, paste, film, fluid injectable, rehydratable freeze-dried paste or sponge, sprayable solution, topically applied patch with adhesive and reservoir system, an intermediate for coatables such as films and bandages, a matrix for membranes, or as a matrix of flexible polymer(s), or delivered as either an orally ingestible liquid, tablet or capsule. The main ingredient of the formulated compositions is hydrolyzed collagen, which can be combined with polysulfated glycosaminoglycans, hyaluronic acid or salts thereof, or a glucosamine salt, and mixtures thereof. The composition may be formulated as an aqueous eye drop solution.

The composition and method for healing tissues is a medicinal composition for facilitating the growth, protection and healing of tissues and cells in animals and humans. The composition is formulated as a either a powder, gel, paste, film, fluid injectable, rehydratable freeze-dried paste or sponge, sprayable solution, topically applied patch with adhesive and reservoir system, an intermediate for coatables such as films and bandages, a matrix for membranes, or as a matrix of flexible polymer(s), or delivered as either an orally ingestible liquid, tablet or capsule. The main ingredient of the formulated compositions is hydrolyzed collagen, which can be combined with polysulfated glycosaminoglycans, hyaluronic acid or salts thereof, or a glucosamine salt, and mixtures thereof. The composition may be formulated with differing concentrations of PSGAG.

The present invention discloses a method for extracting collagen and method for preparing collagen protein by using said collagen. Said method for extracting collagen includes the following steps: using Java tilapia skin as raw material, cutting said Java tilapia skin, adding n-hexane, defatting, using NaOH solution to remove heteroprotein, using acetic acid solution to extract collagen protein, concentrating and freeze-drying so as to obtain collagen. The method for preparing collagen protein by using extracted collagen includes the following steps: adding water to dissolve the collagen, then utilizing proteinase to make zymolysis, concentrating and spray-drying so as to obtain hydrolytic collagen protein.

The invention provides a method for extracting hydrolyzed collagen from bovine cartilage. The method sequentially comprises the following steps of: processing fresh bovine cartilage which is obtained from a Muslim slaughter house and serves as a raw material with solution of sodium hydroxide; adding papain and alkali protease into the obtained product by stages and simultaneously adding a composite enzymolysis protecting agent into the obtained product; raising temperature for inactivating enzyme after two enzymolysis processes; decoloring by oxidation; filtering and performing ultra-filtering; collecting retained solution; and performing spray-drying on the solution to obtain the hydrolyzed collagen. In the method, the bovine cartilage of the Muslim slaughter house is used as a basic rawmaterial, and other animal derived enzyme preparations are not added during the entire process, so that the Muslim property and no pollution of the product can be ensured.

The invention discloses a cosmetic composition favorable for keeping the biological activity of an epidermal growth factor (EGF). The composition mainly comprises the EGF, hydrolyzed collagen powder, sodium hyaluronate, silk peptide powder, palmitoyl pentapeptide and carnosine. The cosmetic composition disclosed by the invention has the characteristics that polypeptides with different structures and molecules are used as main raw materials, polysaccharides are compounded, and various components are similar to the EGF in structure, thereby protecting the EGF; and under the protective action of multiple components which are reasonably combined and matched, the biological activity of the EGF in a cosmetic formula is kept.

The invention relates to a micromolecular donkey-hide gelatin essence anti-aging facial mask, which contains the following components: glycerin, methylpropanediol, glyceryl polyether-26, 1,2-hexanediol, p-hydroxyacetophenone, butanediol, PEG-60 hydrogenated castor oil, panthenol, xanthan gum, allantoin, carbomer, glycerin polyacrylate, tromethamine, sodium hyaluronate, EDTA disodium, glycerin acrylate / acrylic copolymer, phenoxyethanol, propylene glycol, proplis extract, a PVM / MA copolymer, dipotassium glycyrrhizinate, essence, silk amino acids, beta-glucan, BAMBUSA VULGARIS WATER bambusa vulgaris water, hydrolyzed collagen, rice extract, glycine ussuriensis seed extract, sesame seed extract, chondrus crispus extract, ethylhexylglycerin, polysorbates-20, potassium chloride, locust bean gum,dipotassium phosphate, sodium citrate, hydrolyzed hyaluronic acid, glucose, calcium lactate, glucomannan, sodium acetylated hyaluronate and acetyl hexapeptide-8. The micromolecular donkey-hide gelatin essence anti-aging facial mask has the efficacies of supplementing skin nutrition, moisturizing, removing wrinkles and resisting senility.

The invention provides product compositions and a preparation method of neutral liquid high calcium milk. Every 100 weight portions of the neutral liquid high calcium milk comprises the following compositions in portion by weight: 97.50 to 99.05 portions of milk, 0.40 to 0.80 portion of milk calcium, 0.10 to 0.50 portion of hydrolyzed collagen, 0.05 to 0.30 portion of casein phosphopeptides (CPP), 0.20 to 0.60 portion of stabilizing agent and 0.10 to 1.00 portion of dietary fiber. The neutral liquid high calcium milk has high safety and nutrition, good taste, high calcium content and balanced calcium-phosphor proportion, and is easy to be digested and absorbed by human body; moreover, the high calcium milk can meet the requirements of consumers of different age groups on calcium supplementation and is favorable for strengthening bone and articular cartilage.

The invention relates to a facial mask, and particularly relates to a black wolfberry facial mask. The black wolfberry facial mask is prepared by the following steps: preparing anti-wrinkle concentrate from black wolfberry as a main raw material; stirring the concentrate evenly, sterilizing, and soaking facial mask towel made of spunlace nonwoven into the concentrate for 20-30 minutes; and encapsulating in vacuum, wherein the concentrate is prepared from the following raw materials in parts by weight: 10-25 parts of deionized water, 10-25 parts of black wolfberry powder, 2-3 parts of hydrolyzed collagen, 2-7 parts of ethanol, 10-20 parts of a whitening agent and 10-20 parts of a moisturizer. The black wolfberry facial mask disclosed by the invention contains a plurality of anti-wrinkle components, so that the black wolfberry facial mask has the efficacies of delaying skin aging, restoring the skin elasticity, representing tough and compact skin, and reducing sagging, smooth fine lines and wrinkles; and meanwhile, the black wolfberry facial mask contains whitening, nourishing and moisturizing components, so that the skin can be whitened; the moisture of the skin can be locked; dry skin can be restored or improved; and most of raw materials for the product are purely natural raw materials, so that the black wolfberry facial mask is safe and free of thrill.

The invention discloses a method for preparing a sheep placenta extract and a sheep placenta hydrolyzed collagen concentrated solution, which belong to the technical field of utilization of sheep placentas. The method comprises the following steps of: preparing sheep placenta powder from commercially-available freeze-dried sheep placentas serving as a raw material; preparing a crude sheep placenta extract extracting solution; and preparing a sheep placenta extract and a sheep placenta hydrolyzed collagen concentrated solution product. The method has the advantages of easiness, easiness and convenience for operating, simple equipment, mild reaction conditions and saving in energy; by adopting the method, a plurality of products such as the sheep placenta hydrolyzed collagen concentrated solution, a feed additive and the like are prepared simultaneously while the sheep placenta extract is prepared, and comprehensive utilization of the sheep placentas is realized; in a production process, substance resources can be fully utilized, 'three wastes' are not discharged, and the environment is protected; and the production cost is low, and popularization and application are facilitated. The method can be widely used for preparing sheep placenta extract and the sheep placenta hydrolyzed collagen concentrated solution, and a product prepared by using the method can be widely applied in the industries of makeups, health-care products and the like.

The invention discloses a method for recovering collagen and chromium salts from chromium-containing scrap leather residues, which comprises the following steps: carrying out alkaline hydrolysis on chromium-containing scrap leather residues with strong alkali assisted by metal oxide and surfactant, recovering collagen from the filtrate, hydrolyzing the filter residues with strong acid, and sequentially carry out redox reaction to obtain a chrome tanning solution or drying to obtain a powdery chrome tanning agent. The invention has the advantages of fewer steps, short period, high efficiency and low production cost, is simple to operate, and can implement effective separation of chromium and hydrolyzed collagen; the recovered industrial collagen has low chromium content and high added value, and thus, can be used as a raw material for producing other fine industrial chemicals; the recovered chromium salts are free of calcium salts, and thus, can be used as a tanning agent for leather tanning again; and the invention does not generate tailings or wastewater, thereby avoiding secondary pollution.

The invention relates to a soluble micro-pin patch and a preparation method thereof. The pin point of the micro-pin patch is prepared from, by weight, 7-14 parts of hyaluronic acid or salts thereof, 0.05-0.2 part of functional active ingredients, and 6-11 parts of shaped materials; the hyaluronic acid or salts thereof are mixtures of low molecular weight hyaluronic acid or salts thereof and high molecular weight hyaluronic acid or salts thereof, wherein the molecular weight of the small molecular weight hyaluronic acid or salts thereof is less than 10 kDa, the molecular weight of the high molecular weight hyaluronic acid or salts thereof is not less than 1800 kDa; the functional active ingredients are selected from oligo-peptide-1, oligopeptide-3, hydrolyzed collagen, and at least one of the hyaluronic acid or salts thereof; the shaped materials are selected from polyvinyl alcohol and derivatives thereof, polyvinyl pyrrolidone and derivatives thereof, and at least one of lactose, sorbitol, dextran, trehalose and sucrose. The soluble micro-pin patch has the properties of good rigidity and strength.

The invention aims to provide a reproducible heavy metal complexing agent and an application method thereof. In the method, hydrolyzed collagen serving as a complexing agent is applied to a membrane separating process, and heavy metal copper-containing waste water is integrally treated by performing membrane separation-electrolysis. The method mainly comprises the following steps of: enriching; filtering; concentrating; decomplexing; electrodepositing; refluxing and the like to realize efficient recovery of heavy metal copper-containing waste water.

The invention relates to a Chinese medicine preparation, particularly a Chinese medicine preparation capable of increasing bone density and improving osteoporosis and arthralgia. The Chinese medicine preparation contains epimedium extract, radix salviae miltiorrhizae extract, D-glucosamine hydrochloride, biological calcium carbonate (oyster calcium), collagen hydrolysate, chondroitin sulfate and other active ingredients, wherein the D-glucosamine hydrochloride can obviously promote the proliferation and differentiation actions of the epimedium extract and radix salviae miltiorrhizae extract on osteoblasts. By combining the traditional Chinese medicine theory and the modern medicine research, the preparation tonifies the liver and kidney, strengthens the kidney and bone, promotes the bloodcirculation, dredges the collaterals and directly supplements calcium and collagen in a biological way, so that the kidney-qi is sufficient, and the bone is tonified, thereby improving ostealgia and arthralgia, enhancing the quality of life in the turn of life, and further performing the functions of increasing bone density and improving osteoporosis and arthralgia.

The invention discloses a high-quality collagen mask. The high-quality collagen mask is prepared from, by weight, water, glycerin, dipropylene glycol, methylpropanediol, SC glucan, super repair peptide, carnosine, fucogel-1, milk skin conditioner, dipotassium glycyrrhizinate, hydrolyzed collagen, allantoin, preservative, citric acid, methylparaben, sodium hyaluronate, EDTA disodium, PEG-hydrogenated castor oil and essence. The adopted raw materials are free of toxicity, irritation or side effect. The high-quality collagen mask has higher permeability, trophism, repairability, moisture retention property and compatibility and better whitening and wrinkle removing functions than masks available in the market at present, and can improve skin elasticity, shrink pores, remove facial wrinkles, improve dark and oily skin, deeply permeate into skin to provide nutrients and water for skin constantly, and repair aged and damaged cells, so as to realize a long-term skin nourishing effect.

The invention provides a hydrolyzed collagen liposome solution mainly used for repairing skin damages caused by various factors. According to the invention, the hydrolyzed collagen liposome solution is prepared from a phospholipid, a ceramide and cholesterol, a percutaneous stratum corneum of hydrolyzed collagen is promoted to enter the skin, and the retention of the hydrolyzed collagen in the skin is improved, so that the recovery of the skin damages is effectively promoted. Furthermore, the solution contains hyaluronic acid to improve the stability of the liposome and delay leakage.

The invention discloses vegetable protein peptide wrinkle reducing and resilience restoring eye cream. The eye cream is mainly prepared from, by mass, 0.1% to 0.3% of carnosine, 0.3% to 0.7% of hexapeptide-9 / butanediol and 0.3% to 0.8% of tiny euglena polysaccharide / hydrolyzed collagen. According to the prepared vegetable protein peptide wrinkle reducing and resilience restoring eye cream, multiple aging delaying ways are comprehensively applied, carnosine, hexapeptide-9 / butanediol and tiny euglena polysaccharide / hydrolyzed collagen with the specific ratio are adopted and cooperate with one another, and the remarkable effects of skin tightening, restoring, wrinkle resisting and skin improving are achieved. Therefore, the eye cream has the effects of whitening, skin tendering, skin tightening and wrinkle reducing.

The invention discloses a process for preparing hydrolyzed collagen protein using jellyfishes as the raw material, and belongs to the natural resource processing as well as utilizing technical field. The invention uses a novel natural marine biological resource, i.e. jellyfishes, as the raw material for preparing hydrolyzed collagen protein, and realizes the conversion of the role of the jellyfishes from a marine ecological disaster species to a novel natural marine biological collagen protein resource. By operating according to the invention, 2 percent of hydrolyzed collagen protein with more than 95 percent of purity, less than 3000 molecular weight and more than 85 percent of peptides can be obtained. The hydrolyzed collagen protein is known as an important healthy food and cosmetic raw material, and has wide range of application in the clinical medicine, the textile industry and the fine chemical industry, etc. Developing and utilizing the jellyfishes used as the natural marine biological resource has great significance to the fast growing of the jellyfishes, in order to the effective protection of marine ecologic environment of China and to the rapid recovery of the marine fishery.

The invention discloses a preparation method of low-molecular weight collagen. The preparation method of the low-molecular weight collagen comprises pre-treatment, molecular sieve chromatography and ion exchange column separation. Collagen is an important functional factor in a health product, sources, technology and molecular weight become main factors for influencing collagen effects, and molecular weight distribution is directly related to technology. Relative molecular weight is an important index of hydrolyzed collagen and needs to be researched deeply so that a relationship between the relative molecular weight of hydrolyzed collagen and activity of hydrolyzed collagen is ensured. Leftover of fish skin such as cod skin and tilapia skin is orderly subjected to fish-skin impurity protein removal, fish-skin fat removal and fish-skin collagen enzymolysis, and the obtained sample collagen zymolytic polypeptide liquid is subjected to molecular sieve chromatographic separation purification and ion exchange chromatographic separation purification so that high-purity collagen samples having different molecular weights are obtained.

The invention relates to wrinkle-free repair cream. The wrinkle-free repair cream is prepared from the following raw materials in parts by weight: 40 to 80 parts of water, 2.5 to 4 parts of glycerol, 4 to 7 parts of butanediol, 0.8 to 1.2 parts of hydrolyzed collagen, 0.1 to 0.5 part of hyaluronic acid, 0.5 to 1 part of panthenol, 0.8 to 1.2 parts of evening primrose seed extracts, 0.8 to 1.2 parts of oligopeptide-1, 0.8 to 1.2 parts of oligopeptide-2, 1.6 to 2.4 parts of mycose, 4 to 6 parts of horse fat, 0.7 to 1.3 parts of centella asiatica root extracts, 1.3 to 1.8 parts of syringa vulgaris extracts, 1.7 to 2.3 parts of ceteareth-10, 1.3 to 1.8 parts of cetearyl alcohol, 1.7 to 2.3 parts of Shea butter oil and the like. According to the wrinkle-free repair cream and a preparation method of the wrinkle-free repair cream disclosed by the invention, the wrinkle-free repair cream is convenient to use, good in permeability, mild in skin and free of stimulation and harms to skin, and capable of stimulating growth factors to play a role based on the activity of resina draconis.

The invention relates to the technical field of cosmetics, in particular to an essence, a preparation method and application. The essence is prepared from a dosage form I and a dosage form II through mixing, wherein the dosage form I comprises the following components in percentage by mass: 1-3% of a mixture of xylitol glucoside, dehydrated xylitol and xylitol, 1-5% of a water solution of maltooligosyl glucoside and hydrogenated starch hydrolysate, 0.05-0.3% of sodium hyaluronate, 1-10% of glycerinum, 1-10% of butanediol, 0.3-0.8% of an anticorrosion synergist, 0.3-3% of 1,2-hexanediol, 0.5-5% of a stimulating inhibition factor, 0.5-3% of an anti-allergy antipruritic, 0.5-3% of oat beta-glucan solution, 0.5-5% of water-soluble ceramide and the balance of water; the dosage form II is prepared from a mixed solution A through freezing and drying, wherein the mixed solution A comprises the following components in percentage by mass: 0.3-5% of hydrolyzed collagen, 1-20% of mannitol, 0.3-10% of gelatin, 0.003-0.01% of oligopeptide-3 and the balance of water. The essence provided by the invention can be used for effectively solving the skin sensitivity problem caused by excessive skin cornification.

The present invention is crosslinked chitosan-quaternized hydrolyzed collagen preparing process and relates to antibiotic biological material preparation. The crosslinked chitosan-quaternized hydrolyzed collagen is prepared with silkworm pupa chitin and hydrolyzed collagen as material. The preparation process includes mixing two kinds of solution, adding crosslinking agent to perform crosslinking reaction, membrane concentration, regulating pH value, and volumetric or spray drying to produce powder. The present invention can prepare solution or sol product and into the product, various water soluble functional factors, such as skin growth factor, moisture maintaining factor, vitamin, etc. may be added to form multifunctional biological dressing.

The invention discloses an anti-aging and wrinkle-removing composition. The anti-aging and wrinkle-removing composition is prepared from the following components in percentage by mass: 3-10% of hydrolyzed collagen, 3-15% of polypeptide, 0.4-10% of humectant, 1-3% of compound amino acid, 0.5-1% of ceramide-3, 3-10% of polyhydric alcohol, 1-10% of antioxidant, 0.1-1% of preservative, 0.02-1% of chelating agent, 0.1-5% of anti-allergic agent and the balance deionized water. According to the anti-aging and wrinkle-removing composition, the hydrolyzed collagen, the polypeptide, the humectant, the compound amino acid, the ceramide 3, the polyhydric alcohol and the antioxidant are scientifically proportioned according to the structural characteristics of skin and the physiological function requirements of the skin, so that the anti-aging and wrinkle-removing composition can be used for removing wrinkles instantly and removing wrinkles for a long time; and after the anti-aging and wrinkle-removing composition is used for a long time, the effects of reconstructing a skin cell collagen network, deeply removing wrinkles and resisting aging, plumping the skin, improving the water content of epidermal cells, enhancing the skin barrier function, brightening the skin, increasing the skin elasticity and brightening the skin color are achieved.

The invention belongs to the field of cosmetics and particularly relates to a hexapeptide firming essence stock solution and a preparation method thereof. The hexapeptide firming essence stock solution is prepared from propanediol, butanediol, EDTA disodium, allantoin, hydroxyethyl cellulose, xanthan gum, betaine, hyaluronic acid, trehalose, carbomer, triethanolamine, panthenol, niacinamide, hexapeptide, hydrolyzed collagen, dipotassium glycyrrhizinate, phenoxyethanol and water. The hexapeptide firming essence stock solution has the effects of moisturizing and retaining heat, firming the skin, removing thin lines and brightening the skin.

The invention discloses a formaldehyde-free amino resin retanning agent. The formaldehyde-free amino resin retanning agent is characterized by being formed as follows: firstly, obtaining an intermediate containing hydroxyl and aldehyde group residue in molecule by using an amino monomer and glutaraldehyde through nucleophilic addition; then, obtaining the formaldehyde-free amino resin retanning agent by a series of reactions such as sulfonation, hydrolyzed collagen end-blocking, condensation and etherification. The formaldehyde-free amino resin retanning agent provided by the invention is an amino resin condensation product containing an aldehyde group, has retanning performance comparable with that of the conventional amino resin retanning agent, has an aldehyde group capable of performing covalent cross-linking reaction with the amino on collagenous fiber in molecule, and can be used for improving the humidity and heat-resistant stability of finished leather. Formaldehyde is not used in a preparation process of the formaldehyde-free amino resin retanning agent, so that harms of formaldehyde in the finished leather can be greatly lowered.

Health benefits manifested by consuming collagen / hydrolyzed collagen and swiftlet nest exhibit resemblance of each other. Logical instinct should have linked the duos. However, due to age-old assumptions and cultural misplacement, this relationship have been undergrounded. Swiftlet nest has been consumed by Chinese community as a premium delicacy and effective medicine as well as beauty enhancer. So much so that it has become the food of status and command very high price. Due to this reason, the culture of "if it ain't broken, dont fix it" permeated. Double steaming, sometimes called double boiling, is the only widely used cooking method till today, under the belief that over heating above 100 DEG C will destroy the nutrion value of swiftlet nest. This invention is a breakthrough from tradition. Swiftlet nest is cooked above 100 DEG C, using steam sterilization method. Amino acids analysis has been carried out on the sample of the swiftlet nest cooked using this invention. It shows the amino acids profile does fit the amino acids profile of collagen and hydrolyzed collagen. Hence, with this invention, swiftlet nest proved to be a source rich in amino acids and can be used as the raw material to produce collagen and hydrolyzed collagen.

The invention belongs to the collagen hydrolysis field, and in particular to the method for extracting low molecular weight collagen from cattle bone. According to the invention, the cattle bone after being degreased is crushed and grinded to bone meal with particle size of 0.5-1000mum; the bone meal is dispersed in water to form bone slurry, a series postprocessing technology is employed to remove enzymatic hydrolysis and enzymes inactivating is carried out to obtain solid residues and soluble inorganic salt impurity in a protein liquid, thereby the low molecular weight collagen with high purity can be obtained. According to the invention, the low molecular weight collagen product with average molecular weight of 1000-5000g / mol can be obtained, the ash content is lower than 1.5%, and the obtained low molecular weight collagen can be used in food, medicine, and cosmetic and health product.

The invention provides a fresh and cool oil-control silicon oil-free hair shampoo which is composed of lauroyl collagen amino acid, sodium cocoamphoacetate, cocamidopropyl betaine, decyl glucoside, glyceryl laurate, peg-120 methyl glucose dioleate, stearamide propyl dimethyl ammonium, guar gum hydroxypropyl trimethyl ammonium chloride, polyquaternary ammonium salt-10, peg-7 glyceryl cocoate, hydroxyethylurea, capryloyl glycine, citric acid, allantoin, triethanolamine, hydrolysis avenin, hydrolyzed collagen, ginger root oil, palmitamidopropylamine trimethyl ammonium chloride, hexamidine di(ethylenhydrin-sulfonic acid) salt and a matrix. The invention further discloses a making method of the hair shampoo. The hair shampoo is capable of adjusting hair environments, enabling hair to be at a silicon oil free of small silicon oil deposition state, controlling oil, removing dandruff, making hair fresh and cool, nutrificating scalp and hair, repairing damaged hair, preventing hair dry yellow,hair spitting or hair breakage, and making the hair soft and glary.

The invention discloses an eye cream. The eye cream is prepared from glycine soja protein, hydrolyzed rice protein, and superoxide dismutase, is capable of improving eye microcirculation, protecting collagen and elastin matrix, and preventing and reducing eyelets; silane triol and sodium hyaluronate are adopted to increase skin elasticity, and reduce wrinkles; a composition of collagen proteins including hydrolyzed wheat protein, hydrolyzed collagen, and hydrolyzed soy protein is capable of maintaining the compact states of epidermis lipid monolayer molecular membrane, promoting synthesis of collagen, and achieving synergistic anti-wrinkle effects; acetyl hexapeptide-8 is capable of inhibiting contraction of eye muscles, and reducing wrinkles; ceramide and tocopheryl acetate are capable ofmaintaining water in skin, repairing skin barrier, and moisturizing skin. The eye cream is capable of maintaining water and moisturizing skin, preventing and reducing eye dark circles, eye-bags, andfading eye winkles. The invention also discloses a preparation method of the eye cream. The preparation method is simple, and the produced eye cream is stable.