156 results about "Hydrolyzed collagen" patented technology

This invention provides an anti-aging and repairing composition containing collagen and its preparation method, belonging to the technical field of medical, dental, or cosmetic products. Its components consist of hydrolyzed collagen, recombinant type III human collagen, artichoke leaf extract, and fermented blueberry seed oil. This invention uses recombinant type III human collagen and hydrolyzed collagen as its core, overcoming the limitations of traditional collagen through biotechnology, and supplementing it with double-fermented plant ingredients to solve the bottlenecks of transdermal absorption and anti-oxidation. The overall design conforms to the anti-aging triangle logic of "repair, defense, and moisturizing," and has good market prospects.

The present application relates to the technical field of daily chemical products, and specifically discloses a shampoo for improving scalp sensitivity, soothing and repairing, and a preparation method thereof. A shampoo for improving scalp sensitivity, soothing and repairing, the raw materials of the shampoo include sodium laureth sulfate, guar hydroxypropyltrimethylammonium chloride, polyquaternium-47, cocamide MEA, sodium citrate, citric acid, sodium chloride, glycyrrhizic acid and its derivatives, salicylic acid and its derivatives, cocamidopropyl betaine, styrene acrylate copolymer, polydimethylsiloxane, bis-aminopropyl polydimethylsiloxane, hydroxypropyltrimethylammonium chloride hydrolyzed collagen, gliadin, hydrolyzed keratin, and plant-derived ingredients that can help improve scalp sensitivity, and the balance is deionized water.

The present invention describes a biomaterial comprising (a) a collagen composition comprising (i) partially hydrolyzed collagen and (ii) collagen and / or fully hydrolyzed collagen and (b) a polymer. The biomaterial is useful in producing a processed biomaterial which may be a leather-like material.

The invention discloses a planting method of selenium-rich cherries. The planting method comprises the following steps that selenium-containing fertilizer is applied to soil in a flushing mode when tree bodies germinate at the end stage of a dormancy period; in the flowering stage, nitrogen-phosphorus-potassium balanced fertilizer is applied, and the synergist composition and the selenium-enriched nutritional agent are sprayed on leaf surfaces at intervals; and spraying the synergist composition and the selenium-rich nutritional agent on leaf surfaces at intervals for multiple times in a fruit swelling period. The synergist composition disclosed by the invention is prepared from the following components: polyoxyethylene fatty alcohol ether, polyether modified organic silicon, natural plant saponin, chitosan oligosaccharide, alginic acid, hydrolyzed collagen and the like. The selenium content of the cherry fruits cultivated by the method can reach 0.078-0.082 mg / kg, after the cherry fruits are stored for 15 days, the hardness of the fruits is maintained at 65-68.5 N / cm < 2 >, the weight loss rate is controlled at 4.0-4.5%, the rotting rate is controlled at 3.2-3.8%, the retention rate of vitamin C reaches 83-86%, and the storage period is prolonged by 3-4 days compared with that of conventional cultivation. The method is easy to operate, low in cost and high in applicability, and the quality and storage performance of the cherry fruits can be remarkably improved.

The invention provides a preparation method of a hydrolyzed collagen product with surface amphipathicity as well as the product and application thereof, and the preparation method comprises the following steps: (1) taking hydrolyzed collagen enzymatic hydrolysate as a substrate, then preparing a fermentation culture medium with vegetable oil and sugar, and fermenting by adopting candida bumblebee; (2) after fermentation, adding lysozyme into the fermentation liquor for activating treatment, and then sterilizing, centrifuging and filtering; and (3) carrying out freeze-drying treatment on the filtered fermentation liquor to obtain the hydrolyzed collagen product with surface amphipathicity. The hydrolyzed collagen product prepared by the invention not only has low molecular weight and high permeability to skin, but also has water locking and moistening effects on the skin surface due to the amphiphilic sophorolipid on the surface, so that the moisture retention of the skin is better improved, and the product has excellent product characteristics and has wide market prospects.

The invention discloses an Ectoin and hydrolyzed collagen silanol composition as well as a preparation method and application thereof. The preparation method comprises the following steps: preparing a hydrolyzed collagen silanol derivative: hydrolyzing a silane coupling agent in an acidic organic solvent aqueous solution to obtain silanol hydrolysate; the preparation method comprises the following steps: dissolving hydrolyzed collagen in deionized water, adjusting the pH value to 8-10, stirring, adding silanol hydrolysate for reaction, cooling to room temperature, and freeze-drying to obtain hydrolyzed collagen silanol derivative powder; the preparation method comprises the following steps: preparing an Ectoine and hydrolyzed collagen silanol composition: dissolving hydrolyzed collagen silanol derivative powder and Ectoine in pure water together, and carrying out ultrasonic treatment to obtain the Ectoine and hydrolyzed collagen silanol composition, the prepared composition can inhibit skin heat injury, inhibit skin inflammatory response, promote skin collagen regeneration and repair skin barrier, and can be applied as a raw material of skin care products or medical beauty products.

The invention discloses a gynecological antibacterial nursing gel containing hydrolyzed collagen and a preparation method thereof. Comprising the following raw materials in parts by weight: 4 to 12 parts of hydrolyzed collagen, 1 to 3 parts of glutathione, 2 to 4 parts of sophocarpidine, 0.2 to 0.5 part of resveratrol, 1 to 3 parts of hydroxybutyl chitosan, 15 to 20 parts of a traditional Chinese medicine extract, 0.5 to 1.5 parts of sodium hyaluronate, 0.1 to 0.25 part of plant essential oil, 1 to 3 parts of triethanolamine, 0.8 to 1.5 parts of lactic acid, 1 to 2 parts of carboxymethylcellulose, 1 to 1.5 parts of glycerol, 1 to 2 parts of carbomer and 0.5 to 1.5 parts of an emulsifier, 1-3 parts of a pH regulator, 10-15 parts of an irradiation improver, and the balance of purified water, totaling 100 parts; the invention relates to the technical field of gynecological gel. According to the gynecological antibacterial nursing gel containing the hydrolyzed collagen and the preparation method, the antibacterial effect of the gel is enhanced by adding the hydrolyzed collagen, so that the antibacterial effect is more durable, and the hydrolyzed collagen has relatively small molecular weight, is easily absorbed by skin, and can quickly permeate into vaginal mucosa to play nourishing and repairing roles.

The invention discloses a self-crystallization type amino acid cleansing cream composition and a preparation method thereof. Comprising the following components in percentage by weight: 20%-40% of glycerol, 15%-25% of cocoyl glycinate, 1%-10% of cocoyl hydrolyzed collagen potassium, 0.1%-5% of sodium lauroamphoacetate, 0.1%-3% of citric acid, 0.1%-3% of sodium methyl cocoyl taurate, 0.1%-3% of sodium chloride, 0.1%-3% of sodium lauroyl glutamate, 0.1%-3% of ethyoxyl diethylene glycol, 0.1%-3% of propylene glycol laurate, 0.1%-3% of PEG-150 stearate, 0.1%-3% of ethylene glycol distearate, 0.0%-2% of 1, 3-propylene glycol distearate, 0.0%-2% of 1, 3-propylene glycol distearate and the balance of water. The cleaning agent is prepared from the following components in percentage by weight: 0.0 to 2 percent of 1, 2-hexanediol, 0.0 to 2 percent of p-hydroxyacetophenone and The self-crystallization type cleansing cream composition disclosed by the invention is high in crystallization point, good in thermal stability, mild and low in irritation, and has the effects of moisturizing and promoting cell proliferation, and the overall performance is improved.

To provide a topical skin agent which exhibits a synergistically enhanced moisturizing effect through the combined use of specific components.SOLUTION: The present invention provides a topical skin agent comprising the following components (A) to (C): (A) bakuchiol, (B) glyceryl glucoside, and (C) one or more selected from rice fermentation liquid, niacinamide, and hydrolyzed collagen.SELECTED DRAWING: None

A composition is provided that includes hydrolyzed collagen, at least one biguanide, at least one vicinal diol, and at least one chelating agent. The composition exhibits at least 2-log reduction of planktonic microbes within 24 hours. Methods of using the composition are also provided.

The invention discloses a fish hydrolyzed collagen peptide-based flavor beverage and a preparation method thereof, and relates to the technical field of food beverages. The flavored beverage comprises the following raw materials: fish hydrolyzed collagen peptide, a compound flavor modification stabilizer, a compound sweetening agent, concentrated fruit and vegetable juice, casein phosphopeptides, VC magnesium phosphate, zinc lactate, a low-nucleic-acid yeast extract, sodium hyaluronate, an acidity regulator and purified water. The compound flavor modification stabilizer is matched with the low nucleic acid yeast extract to form synergistic flavor regulation and control, the hydrophobic bitter peptide fragment of the fish hydrolyzed collagen peptide and the fishy smell characteristic group are wrapped from the molecular level, and meanwhile, the soft modification on the sensory level is realized through the gamma-aminobutyric acid; the effect of debitterizing and deodorizing without adding artificial essence and a large amount of cane sugar is achieved, the product flavor is natural and harmonious, the sour and sweet taste is palatable, the beverage completely conforms to the current healthy consumption trend of low sugar and no artificial addition, and the problem that the beverage has flavor defects is solved.

The invention discloses tightening and anti-aging massage cream and a preparation method thereof, and belongs to the technical field of cosmetics. The massage cream comprises butanediol, glycerin, allantoin, carbomer, sodium hyaluronate, hydrolyzed collagen, a moistening agent, an emulsifier, a pH regulator, a penetration enhancer, a skin conditioner and an antioxidant. Through scientific and reasonable proportioning, various active ingredients with different effects are compounded, so that the massage cream can directly permeate skin tissues, increase cell viability, promote blood circulation, deeply nourish the skin, comprehensively improve the skin state and remarkably improve the skin compactness; through synergistic cooperation of natural active ingredients such as tetrahydromethylpyrimidinecarboxylic acid, bakuchiol, polypeptide, a plant extract aqueous solution, hydroxypropyl tetrahydropyrantriol and a helichrysum extract, the activity of collagenase can be effectively inhibited, fibroblasts are stimulated to generate collagen, and therefore the skin elasticity is remarkably improved, and meanwhile the purposes of tightening and resisting aging are achieved.

The present invention belongs to the technical field of medical preparations, and specifically relates to an anti-aging composition and a preparation method thereof. The anti-aging composition comprises the following raw materials in parts by weight: 5-10 parts bovine collagen tripeptide, 5-10 parts erythritol, 1-5 parts concentrated apple juice, 0.05-1 parts hydrolyzed collagen, 0.05-1 parts salmon powder, 0.05-1 parts fish maw oligopeptide, 0.05-1 parts golden bell fruit powder, 0.05-1 parts brown sugar powder, 0.05-1 parts albumin polypeptide, 0.05-1 parts sucralose, 1-5 parts anhydrous citric acid, and 55-90 parts purified water. The present invention not only supplements the collagen required by the human body, but also improves skin elasticity and scavenges free radicals.

The present application relates to the technical field of health care products, in particular to a pelvic floor muscle repairing composition containing supermolecular tightening Dropsordry and a preparation method thereof, which comprises the following components in mass fraction: 10-14 parts of protein composition, 20-24 parts of chitosan modified Dropsordry, 5-7 parts of freeze-dried powder of Lactobacillus bulgaricus, 10-12 parts of hyaluronic acid, 6-8 parts of glycine and 15-17 parts of proline; each part of the protein composition comprises 20-30 parts of myosin, 30-34 parts of actin, 5-10 parts of hydrolyzed collagen and 240-280 parts of deionized water. The pelvic floor muscle repairing composition can reduce drug toxicity, reduce the amount of drug administration, continuously supplement the required elements of the body during treatment, and quickly relieve the constipation problem caused by the functional damage of the pelvic floor muscle.

The object of the present invention is to provide a non-invasive agent that, in particular, exhibits a skin-improving effect and reduces the visible signs of aging. For this purpose, the invention provides a liquid oral composition as a food supplement or dietary food, comprising liquid marine hydrolyzed collagen peptides obtained from cod skin.

Provided in the present application are a gel composition containing a hydrolyzed collagen and use thereof. The gel composition comprises a collagen peptide, a hydrolyzed collagen, and a sugar alcohol. According to the mass ratio, hydrolyzed collagen:sugar alcohol = 4-12:3-94. The number of hydroxyl groups in sugar alcohol repeating units is not less than 3. The molecular weight of the collagen peptide is 500-10000 Da. The molecular weight of the hydrolyzed collagen is 10000-20000 Da. In the gel composition, according to the mass ratio, hydrolyzed collagen:collagen peptide = 4-12:2-25.

The invention relates to giant salamander peptide and a preparation method and application thereof, the giant salamander peptide can be obtained by hydrolyzing collagen by neutral protease, pepsin, alkaline protease or trypsin, the average molecular weight is 200-5000 Da, and the polydispersity index is 1.2-1.5. The preparation method comprises the following steps: raw material treatment: obtaining giant salamander skin tissues, degreasing and decolorizing the giant salamander skin tissues with ethanol and deionized water, and air-drying; preliminary enzymolysis and separation: performing preliminary hydrolysis by using pepsin, adjusting the pH value, performing salting-out precipitation, and performing centrifugal collection; purification and preparation of a collagen solution: dialyzing to remove impurities and freeze-drying to prepare collagen, and dissolving to form the collagen solution; enzymolysis, separation and purification: adding protease for hydrolysis, centrifuging after enzyme deactivation, filtering, carrying out molecular weight grading purification, and freeze-drying to obtain the giant salamander peptide. The invention provides the method for efficiently extracting the giant salamander collagen peptide, the purity and uniformity of the giant salamander peptide are improved, the dispersity index is reduced, and the method is suitable for the fields of functional health care products, medicines and cosmetics.

The present invention relates to a pharmaceutical composition and method for treating skin conditions. The composition comprises a hydrogel film containing an effective amount of at least one active ingredient selected from hydrolyzed collagen, sodium hyaluronate, aloe barbadensis leaf extract, tocopheryl acetate, and rosa rugosa flower oil, along with one or more gelling agents capable of forming a co-polymer network. The hydrogel film is configured to adhere to the skin and deliver the active ingredient in a targeted and prolonged manner. The method involves applying the film to an affected area of the skin for a period sufficient to treat conditions such as sunburn, dryness, and eczema. The invention provides a convenient and effective means of delivering active ingredients directly to the skin while maintaining the structural integrity of the film during use.

The present invention relates to a method for producing a collagen peptide preparation containing recombinant collagen peptides. The method is characterized in that it comprises the following steps: a) providing an in vitro expression system including at least one expression cassette, the expression cassette including at least one nucleotide sequence encoding a collagen peptide having a molecular weight in the range of 8 to 100 kDa; b) incubating the expression system under conditions that allow expression of the collagen peptide; c) obtaining the collagen peptide; d) hydrolyzing the collagen peptide under conditions that result in the production of a collagen peptide preparation including collagen peptides having an average molecular weight of 1 to 5 kDa and a molecular weight in the range of 0.1 to 12 kDa; wherein no more than 5.5% by weight of the hydrolyzed collagen peptides have a molecular weight of less than 500 Da, no more than 2.8% by weight of the hydrolyzed collagen peptides have a molecular weight between 7500 Da and 13500 Da, and between 35% and 60% by weight of the hydrolyzed collagen peptides have a molecular weight between 1500 Da and 3500 Da; e) obtain the collagen peptide preparation.

The invention discloses novel efficient nourishing leather oil and a preparation method thereof. The novel efficient nourishing leather oil is prepared from a natural vegetable oil matrix, hydrolyzed collagen, nano silicon dioxide aerogel, a vegetable wax compound, an antioxidant system and a bioactive penetrant. The preparation method adopts a low-temperature gradient mixing and high-pressure homogenizing process to realize stable dispersion of active components. Tests show that the penetration depth of the product reaches 2.3 times that of a traditional product, the wear resistance is improved by 40%, the biodegradation rate is larger than 90%, and the product is suitable for long-acting maintenance of high-grade leatherware.

The invention discloses an instant giant salamander collagen freeze-dried ball and a preparation method thereof. The freeze-dried ball comprises 10-20 parts of giant salamander hydrolyzed collagen, 10-15 parts of mannitol and 30-50 parts of sodium polyglutamate. The freeze-dried ball can be combined with the giant salamander hydrolyzed collagen through electrostatic interaction or hydrogen-bond interaction by utilizing the compounding effect of the sodium polyglutamate and the mannitol, so that the giant salamander hydrolyzed collagen is prevented from being gathered, the giant salamander hydrolyzed collagen can be helped to be better dispersed in water, and meanwhile, the sodium polyglutamate has good moisture retention, water absorption and biocompatibility, so that the freeze-dried ball can be used for preparing the giant salamander hydrolyzed collagen. The mannitol can form a stable supporting structure in the freeze-drying process, so that the giant salamander hydrolyzed collagen is prevented from shrinking or deforming in the freezing and drying processes, the activity of the giant salamander hydrolyzed collagen is protected, and the mannitol can be matched with the sodium polyglutamate in the dissolving process, so that the giant salamander hydrolyzed collagen can be dissolved in the freeze-drying process; the giant salamander hydrolyzed collagen is quickly released, and the dissolving speed is increased.

The present invention relates to a hydrolyzed collagen formulation for use in decreasing blood glucose. The hydrolyzed collagen is obtained by enzymatic hydrolysis of a collagen-containing material with a combination of enzymes comprising two or more enzymes selected from the group consisting of a neutral protease, a carboxypeptidase, and an aminopeptidase. The hydrolyzed collagen formulation is particularly suitable as a food supplement, such as for use in ameliorating hyperglycemia and / or a risk factor hyperglycemia.

To provide a collagen hydrolysate for improving endurance performance and / or for stimulating lipid metabolism.SOLUTION: The present invention relates to the use of a collagen hydrolysate for improving endurance performance by increasing mitochondrial activity. Further, the invention relates to the use of a collagen hydrolysate for stimulating lipid metabolism, and in particular for reducing body weight, by increasing mitochondrial activity.SELECTED DRAWING: Figure 1

The invention relates to the technical field of collagen, in particular to an enzyme for hydrolyzing collagen and application. The enzyme has an amino acid sequence having at least 90% sequence identity to SEQ ID NO: 3. The enzyme can hydrolyze collagen under the enzymolysis condition of 80 DEG C, and has higher enzyme activity and hydrolytic activity on insoluble collagen.

The invention discloses a method for improving the binding force of an electrolytic copper foil and a base material under low roughness and the electrolytic copper foil. The method comprises the following steps: 1) carrying out smooth acid pickling on a 9-35 [mu] m raw foil; (2) performing picosecond laser selective ablation on bulges of more than 100nm on the surface of the pickled raw foil to enable Ra to be less than or equal to 0.1 mu m; (3) depositing a compact copper layer of 0.1-0.4 mu m to fill the micro pits; 4) coarsening in a coarsening solution containing copper ions, sulfuric acid, sodium tungstate and sodium molybdate; 5) curing in a curing liquid containing copper ions, sulfuric acid, MPS, HEC, PEG and hydrolyzed collagen; (6) heat-resisting treatment and passivating treatment are conducted in sequence; 7) spraying an organic silane coupling agent; and (8) drying at 130-140 DEG C for 5-10 seconds, and then rolling at the speed of 4-6 m / min. According to the method, the formation of a high-roughness structure is avoided through laser leveling, the compact copper layer reinforces the substrate to improve the uniformity of copper nodules, the lamination surface Rz of a final product is smaller than or equal to 1.5 microns, Ra is smaller than or equal to 0.2 microns, the peel strength is larger than or equal to 0.7 N / mm, no copper powder falls off during lamination, and the method is suitable for preparing the high-precision copper foil.

The invention relates to an anti-aging composition, a firming and glowing essence containing the anti-aging composition and a preparation method of the firming and glowing essence. The anti-aging composition is prepared from the following components in parts by weight: 1.5 to 6 parts of glyceryl polyether-26, 1.5 to 5 parts of nicotinamide, 0.25 to 1.2 parts of xylitol, 0.13 to 0.3 part of sodium hyaluronate, 0.01 to 0.3 part of carnosine, 0.01 to 0.1 part of PCA sodium, 0.005 to 0.05 part of hydrolyzed collagen, 0.006 to 0.03 part of palmitoyl tripeptide-5, 0.0008 to 0.01 part of hexapeptide-9 and 0.001 to 0.01 part of dipeptide diaminobutyryl benzyl amide diacetate. Test results show that the tightening and glowing essence developed by adopting the composition has the effects of instantly supplementing moisture for skin, promoting collagen generation, improving wrinkles and helping the skin to recover a supporting structure so as to slow down aging, and has a good market prospect.

The invention provides a freeze-drying composition capable of improving skin feeling as well as a preparation method and application of the freeze-drying composition. The freeze-drying composition comprises hydrolyzed collagen, sodium polyacrylate, sodium alginate and functional components, the functional component comprises any one or a combination of at least two of madecassoside, pentapeptide-48 or oat beta-glucan. The hydrolyzed collagen, the sodium polyacrylate and the sodium alginate in the freeze-dried composition disclosed by the invention are synergistically matched, so that the stability of a product and the use skin feeling of the product can be improved, and the activity of functional components is improved.

To provide a liquid skin detergent composition having high moisturizing power to the skin after towel drying.SOLUTION: (A) at least one selected from the group consisting of hydrolyzed collagen and hydrolyzed silk.SELECTED DRAWING: None

Hydrolyzed collagen compositions are described which are used for treatment of impaired cartilage or to prevent damage to healthy cartilage. These compositions function across multiple cartilage components and structures. Oral, topical, or cartilage-site delivery of the compositions to cartilage may be via liquid, gel, powder, or sheet form. Additionally, the hydrolyzed collagen composition may be applied as a coating on a medical device.

The invention relates to collagenase as well as a coding gene and application thereof. The collagenase provided by the invention is a protein (a) or (b), wherein (a) is a protein composed of an amino acid sequence as shown in SEQ ID No: 1; and (b) a protein which is obtained by substituting, deleting or adding one or more amino acids in the amino acid sequence in (a), has collagen hydrolysis or fat dissolving activity and is derived from (a). The collagenase provided by the invention can be applied to cell separation and tissue digestion, fat dissolution or collagen dissolution, and can also be applied to preparation of medicines for treating Doltt's contracture, Petroleum disease and lumbar disc herniation and degreasing in the field of beauty.