41 results about "Log reduction" patented technology

Sterilization methods and apparatus are effective to achieve a 6-log reduction in CFUs of industry standard bacteria and bacterial spores, i.e., B. stearothermophilus and B. subtilis spores, by subjecting sterilizable materials to a chemical additive-containing carbon dioxide sterilant fluid at or near its supercritical pressure and temperature conditions. Most preferably, the chemical additive-containing supercritical carbon dioxide sterilant fluid is agitated during sterilization, e.g., via mechanical agitation or via pressure cycling.

Methods and apparatus are provided for decreasing the bacteria count of a food commodity without affecting its overall organoleptic quality (taste, odor, and color). This is accomplished using a treatment fluid comprising ozone, which is injected into a treatment chamber containing the food commodity. Some water is preferably added to obtain better contact of the ozone with the food by forming a thin film of ozonated water on the food surface. Spices and / or other ingredients may preferably be added with the water. The food is placed in a tumbler and the tumbler is set in motion. During treatment good contact between the treatment fluid and the food commodity is obtained by reversibly oscillating the tumbler. A log reduction of 40% or more in bacteria count may be obtained as compared without the ozone.

A method of moisturizing while decolonizing mammalian tissue, the method comprising applying a multi-valent cationic antiseptic composition to the tissue, and applying a moisturizer composition to at least a portion of the same tissue; wherein the mammalian tissue is oral tissue of a subject; wherein the multi-valent cationic antiseptic is other than a metal ion; and wherein the applied compositions essentially exclude any component which causes a precipitate when combined with a multi-valent cationic antiseptic contained in the multi-valent cationic antiseptic composition when tested according to Test Method F, and / or wherein the moisturizer composition is such that a log reduction in the number of viable bacterial cells of at least 2 is provided when 106 cfu of Pseudomonas aeruginosa are combined with a mixture 1.1 g of the moisturizer composition and 1.5 g of the multi-valent cationic antiseptic composition containing 0.12 weight percent of the multi-valent cationic antiseptic according to Test Method B; an oral care kit comprising a composition comprising the multi-valent cationic antiseptic and the moisturizer composition; and a method of moisturizing oral tissue of a patient requiring intubation using the moisturizer composition and an endotracheal tube coated or impregnated with a cationic antiseptic are provided.

Sterilization methods and apparatus are effective to achieve a 6-log reduction in CFUs of industry standard bacteria and bacterial spores, i.e., B. stearothermophilus and B. subtilis spores, by subjecting sterilizable materials to a chemical additive-containing carbon dioxide sterilant fluid at or near its supercritical pressure and temperature conditions. Most preferably, the chemical additive-containing supercritical carbon dioxide sterilant fluid is agitated during sterilization, e.g., via mechanical agitation or via pressure cycling.

An absorbent wound dressing comprises a hydrophilic porous substrate and polymer-stabilized silver nanoparticles distributed throughout the porous substrate. The silver nanoparticles have a particle size d50 in the range of about 45 nm to about 85 nm and the silver nanoparticles are present in the substrate in an amount of about 0.16% to about 1.5% by weight of the total weight of the substrate. The wound dressing produces a 7-day log reduction of 4 or more for bacteria in accordance with the Modified AATCC Test Method 100. The wound dressing is also non-cytotoxic in accordance with ISO 10993-5 standard procedure for medical device cytotoxicity assessment.

A sterilization method for drugs to achieve a 6-log reduction in CFUs of industry standard bacteria and bacterial spores is effective by subjecting the drugs to a chemical additive-containing carbon dioxide sterilant fluid at or near its supercritical pressure and temperature conditions and controlling the pressurization and depressurization rates.