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53 results about "Bacterial spore" patented technology

A bacterial spore is a spore or spore-like structure produced by bacteria. These include endospores, Akinetes, and spores produced by Actinobacteria and Azotobacter. Spore formation in bacteria is not a method of reproduction but simply a method of surviving unfavourable conditions. They have a number of features: They can tolerate extreme dryness. Some cannot be killed even at subzero temperatures. Some can spread poisonous chemicals, such as the Cry toxin synthesised by Bacillus thuringiensis Bacterial spores are extremely resistant. Spores of tetanus and anthrax, for example, can survive in the soil for many years. The origin of these spores was discovered in the 19th century, when a biologist noticed, under the microscope, a small, round, bright body inside bacterial cells. This survived even when the bacteria were boiled for five minutes. This killed the bacteria, but not the spores. They germinated when conditions were right. Because spores are so resistant, they are highly transmissible. This makes them a very problematic aspect of spore-forming pathogens such as Clostridium difficile.

Compositions and methods

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
Owner:SERES THERAPEUTICS INC

A hygiene composition

The present invention relates to a composition that is used to primarily disrupt and remove biofilm from surfaces. This is achieved using a composition comprising a bacteriophage capable of lysing bacteria selected from one or more of Pseudomonas aeruginosa, Acinetobacter baumanii, Staphylococcus aureus, and E.coli; and a Bacillus bacterial spore in the presence of a specific surfactant of the poloxamer type.
Owner:UNILEVER IP HLDG BV +2

Delayed release of an active ingredient preparation comprising bacterial spores

The invention relates to a device (1) for releasing water-soluble active ingredient preparations (5, 6) into a toilet bowl, comprising a receptacle (2) to be arranged in the toilet bowl, wherein the receptacle (2) can be secured to the toilet bowl, wherein the receptacle (2) comprises at least one first chamber (3) and a second chamber (4), wherein the first chamber (3) releases a first active ingredient preparation (5) into the toilet bowl when flushing water flows over it, and the second chamber (4) releases a second active ingredient preparation (6) into the toilet bowl when flushing water flows over it, and wherein the chambers (3, 4) are designed such that the first active ingredient preparation (5) and the second active ingredient preparation (6) are released into the toilet bowl at different times from one another, characterised in that either the first active ingredient preparation (5) and / or the second active ingredient preparation (6) contains bacterial spores.
Owner:HENKEL KGAA

Method for obtaining bacteria in sterile environments that develop spores resistant to high temperatures

The invention relates to a method for increasing the sporulation of bacteria such as Bacillus velezensis and Paenibacillus polymyxa using a liquid medium comprising glucose, ammonium sulfate, magnesium chloride and non-ionic surfactant polymer compounds. This method for increasing sporulation is used in a method for generating a large quantity of spores and selecting spores more resistant to higher temperatures than the spores of wild strains. The spores with higher heat resistance than those of the wild strains can be used in a method for eliminating contamination in fermentations.
Owner:ALPEK SAB DE CV

Fabric treatment using bacterial spores

A method of treating a fabric in a washing machine using a cold and / or a quick program, including contacting the fabric with a treatment liquor comprising at least 1×102 CFU / l of liquor, of bacterial spores wherein the cold program includes a wash having a bath temperature below 30° C. and / or the quick program lasts less than 40 minutes.
Owner:PROCTER & GAMBLE CO

A method for identifying, imaging, and characterizing bacterial spores using lanthanide-β-diketones

The sample was treated with the formula Ln[BD] n wherein Ln is a member of the lanthanide series of elements, BD is a β-diketone, and n is an integer, to stain one or more bacterial spores in the sample; and detecting a fluorescent signal from the one or more stained bacterial spores in the sample using a fluorescence microscope.
Owner:TEMASEK LIFE SCIENCES LABORATORY LTD

Strain tank with double sterilization methods

The invention relates to the technical field of strain tanks, and discloses a strain tank with double sterilization methods, the strain tank comprises a tank body, a cover body, a stirring motor, a stirring rod and a discharge pipe, the bottom surface of the tank body is fixedly connected with a steam pipe, the upper surface of the cover body is provided with a fixing opening in a penetrating manner, and the inner wall of the fixing opening is connected with a telescopic assembly; the other end of the telescopic assembly penetrates into the tank body and is connected with an ultraviolet lamp, the stirring rod is sleeved with the ultraviolet lamp, the top face of the inner wall of the cover body is connected with an expansion-shrinkage assembly, one end of the expansion-shrinkage assembly communicates with the end, away from the ultraviolet lamp, of the telescopic assembly, and the steam pipe communicates with the interior of the tank body. According to the strain tank with the double sterilization methods, the high-temperature steam sterilization mode and the ultraviolet sterilization mode are combined, a complementary and synergistic sterilization system is formed, and high-temperature-resistant microorganisms and bacterial spores can be effectively killed; through a linkage mechanism of the expansion and contraction assembly and the telescopic assembly, the ultraviolet lamp can automatically ascend and descend in the sterilization process, and all-directional dead-corner-free sterilization in the tank body is achieved.
Owner:XINJI WANLONG EDIBLE FUNGUS LLC

Laundry additive including perfume, bacterial spores and enzymes

Particulate laundry additive composition having a plurality of particles wherein each of said particles has a mass between about 1 mg to about 5000 mg, the composition including:i) at least about 60% by weight of the composition of particle A, wherein particle A includes at least 40% by weight of the particle of a carrier, from about 0.1% to about 10% by weight of the particle of perfume and the particle is substantially free of Bacillus spores and enzymes; andii) at least about 2% by weight of the composition of particle B, wherein particle B includes at least about 40% by weight of the particle of a carrier, from about 0.0001% to about 5% by weight of the particle of Bacillus spores and enzymes and less than about 0.01% by weight of the particle of perfume.
Owner:PROCTER & GAMBLE CO

Laundry additive comprising perfume, bacterial spores and enzyme

The present disclosure relates to laundry additives comprising a perfume, bacterial spores, and an enzyme. A particulate laundry additive composition having a plurality of particles wherein each of the particles has a mass of between about 1 mg to about 5000 mg, the composition comprising: i) at least about 60% by weight of the composition of particles A, wherein particle A comprises at least 40% of a carrier by weight of the particle, from about 0.1% to about 10% of a perfume by weight of the particle, and the particle is substantially free of Bacillus (Bacillus) spores and enzymes; and ii) at least about 2%, by weight of the composition, of a particle B, wherein the particle B comprises at least about 40%, by weight of the particle, of a carrier, about 0.0001% to about 5%, by weight of the particle, of bacillus spores and enzymes, and less than about 0.01%, by weight of the particle, of a perfume.
Owner:PROCTER & GAMBLE CO

Fusion protein of flounder netshell virus nucleocapsid protein, bacillus subtilis expressing fusion protein and oral vaccine

PendingCN121717916ABacteriaViral antigen ingredientsFusion Protein ExpressionTGE VACCINE
The invention provides a fusion protein of flounder netshell virus nucleocapsid protein, bacillus subtilis for expressing the fusion protein and an oral vaccine, and relates to the technical field of biology. According to the present invention, the sequence of the bacillus subtilis anchoring protein CotC is obtained through sequencing, the bacillus subtilis anchoring protein CotC and the flounder nested virus are fused, and after the fusion protein is introduced into the bacillus subtilis, the fusion protein can be anchored on the surface of the bacterial spore, and can be used for preparing the recombinant oral vaccine capable of being stably stored and directly fed, and a new method is developed for preventing the flounder netlike virus CSBV.
Owner:BEIDAIHE CENT EXPERIMENTAL STATION OF CHINESE ACAD OF FISHERY SCI

Duck liver preservation technology based on low-temperature heat treatment and processing device

The invention discloses a duck liver fresh-keeping process based on low-temperature heat treatment and a processing device. The duck liver fresh-keeping process comprises the following steps: cleaning and sorting duck livers; performing low-temperature heat treatment on the cleaned and sorted duck liver in a low-temperature heat treatment device; placing the duck liver subjected to low-temperature heat treatment in a high-pressure treatment device for high-pressure treatment; placing the duck liver subjected to high-pressure treatment in a radiation sterilization device, and performing radiation sterilization treatment; and packaging the duck liver subjected to radiation sterilization treatment. According to the method, bacteria, molds, saccharomycetes and bacterial spores can be thoroughly inactivated at a deeper level by combining high-pressure treatment and radiation sterilization technologies, the quality of microorganisms inside and outside the product is ensured to meet the standard, so that the shelf life of the product is effectively prolonged, the survival possibility of the microorganisms can be effectively eliminated by comprehensively applying multiple sterilization technologies, and the product quality is improved. The existence of pathogenic microorganisms in the food is reduced, the safety of the food is improved, and the risk of food-borne diseases caused by bacterial infection is reduced.
Owner:HUOQIU MINNONG POULTRY CO LTD

Water-soluble unit dose article

To provide a detergent article providing improved malodor removal even when used in a short cycle at a low water temperature.SOLUTION: A water-soluble unit dose detergent article comprising a water-soluble film and a detergent composition, wherein the water-soluble film comprises bacterial spores.SELECTED DRAWING: None
Owner:PROCTER & GAMBLE CO

Liquid food sterilization method based on cooperation of magnetic induction electric field and composite bacteriostatic agent

The invention provides a liquid food sterilization method based on synergy of a magnetic induction electric field and a compound bacteriostatic agent, which comprises the following steps: firstly, adding the prepared compound bacteriostatic agent into liquid food, standing, and triggering citric acid release by utilizing glucose oxidase in the compound bacteriostatic agent to catalyze acid production so as to realize primary bacteriostasis; then, a magnetic induction electric field is started, L-alanine and alanyl-glycine are induced to be synergistically released, bacterial spores are efficiently promoted to be converted from a dormant state to a nutritional state, meanwhile, the magnetic field drives magnetic particles to move, thyme essential oil nano-emulsion is released through mechanical extrusion, and the germinated spores are killed immediately; and long-term bacteriostasis is realized through slow release of the essential oil subsequently. According to the scheme, the industrial problems that an existing low-temperature sterilization technology is low in spore inactivation efficiency, and an efficient natural bacteriostatic agent is unstable, difficult to dissolve or affects flavor are effectively solved, the commercial sterile requirement is met under the mild condition, and the shelf life of liquid food is remarkably prolonged.
Owner:HENAN UNIV OF ANIMAL HUSBANDRY & ECONOMY

8-fluoro-4-alkylumbelliferyl alpha-d-glucopyranoside, biological sterilization indicator including the same and its use in a method of determining efficacy of a sterilization process

A self-contained biological sterilization indicator comprises: a housing; bacterial spores comprising, and / or capable of producing, an enzyme capable of catalyzing cleavage of an enzyme substrate; and a frangible container containing a composition, wherein the composition comprises the enzyme substrate, wherein if the frangible container is broken the composition will contact the bacterial spores to form a mixture having an initial pH in the range from 6.0 to 9.0. The enzyme substrate comprises a fluorinated 4′-alkylumbelliferyl α-D-glucopyranoside represented by the structural formulawherein R is an alkyl group having from 1 to 12 carbon atoms. A biological sterilization indicator comprising a kit containing isolated components comprising (i) bacterial spores comprising, and / or capable of producing, an enzyme capable of catalyzing cleavage of the enzyme substrate and a method of assessing efficacy of a sterilization process are also disclosed.
Owner:SOLVENTUM INTELLECTUAL PROPERTIES CO

Pressure cooker float valve locking device for prolonging preservation time of food at normal temperature and pressure cooker

The utility model discloses a pressure cooker float valve locking device for prolonging the preservation time of food at normal temperature and a pressure cooker, and belongs to the technical field of pressure cookers. An existing pressure cooker cannot guarantee that food in the pressure cooker cannot deteriorate after being stored for a long time at normal temperature, and the reason is that although the temperature in the pressure cooker is up to more than 120 DEG C during high-pressure cooking, all bacteria and bacterial spores in the pressure cooker are killed, but after the pressure cooker stops high-pressure cooking, the bacteria and bacterial spores cannot deteriorate along with the reduction of the air pressure in the pressure cooker. The float valve on the pot cover can automatically fall, at the moment, various bacteria and molds outside the pot can enter the pot through the ventilation hole channel of the float valve, and a large amount of bacteria and molds can be rapidly propagated in cooked food in the pot. The float valve which floats upwards on the pot cover is locked through the float valve locking device; after the pressure cooker stops heating and the air pressure in the cooker is reduced, the sealing state in the cooker is continuously kept, so that bacteria and molds outside the cooker are prevented from entering the cooker through the ventilation hole channel of the float-controlled valve, and the preservation time of food in the pressure cooker at normal temperature is prolonged.
Owner:钟保国

Composition

A laundry liquid composition comprising a surfactant, a polyamine and bacterial spores and a method for treating textiles.
Owner:UNILEVER IP HLDG BV

Compositions for modulating gut microflora populations, for treating dysbiosis, and for disease prevention, and methods for making and using same

In alternative embodiments, compositions, e.g., articles of manufacture and kits, and methods are provided that include combinations or formulations of microorganisms, e.g., live non-pathogenic bacteria and / or bacterial spores, e.g., as probiotics, for the control, amelioration, prevention, and treatment of diseases or conditions, e.g., dysbiosis, or to increase the health or developmental capacity of an individual. In alternative embodiments, compositions or formulations, e.g., articles of manufacture and kits, and methods are provided that include at least one live non-pathogenic bacteria and / or bacterial spore and at least one probiotic or synbiotic. In alternative embodiments, these live non-pathogenic bacteria and / or bacterial spores (and optionally probiotics) are administered to an individual in need thereof, thereby resulting in the alteration or modulation of the individual's intestinal microflora population.
Owner:ペルセフォネ バイオサイエンシーズ インコーポレイテッド

Aqueous agrochemical formulations comprising bacterial spores

Process for making liquid dispersion formulations comprisinga) at least one type of bacterium spores,b) an aqueous continuous phase comprising at least one glycol, wherein said glycol is comprised in the formulation in a weight amount that exceeds the weight amount of water,c) optionally at least one surface active compound S, andd) optionally further auxiliaries,A. providing a solid powder of Bacterium spores,B1. dispersing said spores in a continuous phase comprising at least one glycol, wherein the weight ratio of said at least one glycol to water is below or equal to 1:1,B2. adding further glycol to the dispersion obtained in step B1. to obtain a ratio of said at least one glycol to water from 4:1 to 1.2:1,C. adding at least one surfactant S,D. optionally adding at least one thickener,E. optionally adding further auxiliaries,wherein steps C, D and E can be carried out at any time during the process.
Owner:BASF CORPORATON

Pyridinedicarboxylic acid electrochemical sensor based on intramolecular DNA nano-machine

The invention discloses a construction method, a construction structure and application of a picolinic acid electrochemical sensor based on an intramolecular DNA nano machine. The construction method comprises the following steps: preparing an X-type DNA nano structure, constructing a sandwich composite probe SSC, constructing an electrochemical sensing interface for detecting picolinic acid, and quantitatively detecting picolinic acid in a bacterial sample. According to the electrochemical sensor for detecting the dipicolinic acid, the reaction probe is immobilized by using an X-type nano bracket XSP, an intramolecular DNA nano machine is constructed, efficient signal output is performed through catalytic oxidation reduction cycle amplification, sensitive detection of the dipicolinic acid released by bacterial spores is realized, and the detection limit is as low as 7.4 pM. The research has important application value in the aspects of prevention, diagnosis and treatment of diseases such as anthrax.
Owner:XUZHOU NORMAL UNIVERSITY

Compositions for modulating gut microflora populations, enhancing drug potency and treating cancer, and methods for making and using same

ActiveUS12714730B2Spore germinationUrolithin
In alternative embodiments, provided are compositions, including products of manufacture and kits, and methods, for or comprising administering to an individual in need thereof an inhibitor of an inhibitory immune checkpoint molecule and / or a stimulatory immune checkpoint molecule and a formulation, wherein the formulation comprises at least two different species or genera of non-pathogenic, live bacteria, and each of the non-pathogenic, live bacteria comprise non-pathogenic colony forming live bacteria, a plurality of non-pathogenic germinable bacterial spores, or a combination thereof, and optionally the non-pathogenic bacteria or non-pathogenic bacteria arising from germination of the germinable spores can individually or together metabolize urolithin A from ellagic acid, or can individually or together synthesize urolithin A.
Owner:PERSEPHONE BIOSCIENCES INC

Cleaning composition containing nonionic surfactants and bacterial spores

The invention relates to a cleaning composition comprising a nonionic surfactant; and bacterial spores of the genus Bacillus. The invention further relates to the use of the composition for cleaning toilets or hard surfaces.
Owner:HENKEL KGAA

Compositions for modulating gut microflora populations, enhancing drug potency and treating cancer, and methods for making and using same

Provided are compositions, including products of manufacture and kits, and methods, comprising combinations of microbes, such as non-pathogenic, live bacteria and / or bacterial spores, for the control, amelioration, prevention, and treatment of a disease or condition, for example, a cancer. In alternative embodiment, these non-pathogenic, live bacteria and / or bacterial spores are administered to an individual in need thereof, thereby resulting in a modification or modulation of the individual's gut microfloral population(s). In alternative embodiments, by modulating or modifying the individual's gut microbial population(s) using compositions, products of manufacture and methods as provided herein, the pharmacodynamics of a drug administered to the individual is altered, thereby controlling, ameliorating, preventing and / or treating of that cancer. Combinations of microbes are administered with chemotherapy, radiation therapy, an immune checkpoint inhibitor, a Chimeric Antigen Receptor T-cell therapy or other immunotherapy or cancer treatment.
Owner:PERSEPHONE BIOSCIENCES INC