23 results about "Antimicrobial efficacy" patented technology

The disclosure relates to compositions, including ready-to-use spray or wipe compositions, that are non-toxic, non-corrosive, biodegradable acidic antimicrobial compositions that exhibit broad-spectrum antimicrobial efficacy, wherein the compositions comprise an amine oxide, such as an alkyl amine oxide, in combination with an acidulant. Beneficially, the acidic antimicrobial compositions are capable of achieving at least a 3-log microbial reduction within 5 minutes under relatively mild pH conditions. The compositions provide cleaning and sanitizing.

The present invention relates to ophthalmic formulations in which a synergistic combination of three different types of disinfectants (a polybiguanide compound, a quaternary ammonium compound and an antifungal / anti-acanthamoeba compound), in particular a combination of polyhexamethylene biguanide, polyquaternium-1 and myristoylaminopropyl dimethylamine, high concentrations of hyaluronates are enabled to provide better comfort and support for corneal health without compromising antimicrobial efficacy. The novel ophthalmic formulations support the use of hyaluronates at concentrations greater than 7.5 times as high as currently commercially available multi-purpose disinfectants.

The present invention relates to ophthalmic formulations wherein a synergistic combination of three different classes of disinfectants (a multimeric biguanide compound, a quaternary ammonium compound and an antifungal / anti-acanthamoeba compound, in particular a combination of polyhexamethylene biguanide, Polyquaternium-1 and myristamidopropyl dimethylamine) enables the use of high concentrations of hyaluronate for providing better comfort and support of corneal health without compromising antimicrobial efficacy. The novel ophthalmic formulations support the use of more than 7.5 times higher concentrations of hyaluronate than are present in currently marketed multi-purpose disinfection solutions.

The present application discloses an antimicrobial nylon material, along with its preparation method and application. The present application relates to the technical field of antimicrobial polymer materials and addresses the limitations of existing antimicrobial nylon 6, particularly its insufficient antimicrobial efficacy and challenges in scalability for industrial production. In the present application, a seven-membered cyclic lysine-derived monomer is copolymerized with a lactam via hydrolytic copolymerization using water as an initiator, yielding a copolyamide. The resulting copolyamide is then subjected to a protonation reaction through heating and stirring in an acidic solution, followed by purification to obtain the final antimicrobial nylon material. The seven-membered cyclic lysine-derived monomer may be an unprotected cyclic lysine monomer, a mono-protected cyclic lysine monomer, or a salt form cyclic lysine monomer. The present invention exhibits broad applicability in antimicrobial-sensitive fields such as textiles, plates, pipes, packages or panels.

Cleaning and disinfecting compositions capable of providing antimicrobial efficacy to inanimate surfaces are disclosed. The cleaning and disinfecting composition employs a mixture of an organic acid and a hydrotrope. The cleaning and disinfecting composition is substantially free of alcohol or glycol ether non-aqueous solvents.

The present invention relates to kits, methods and systems for modulating free iodine in PVP-I, facilitating antimicrobial action while also ensuring compatibility with diagnostic assays.

The disclosure relates to compositions, including ready-to-use spray or wipe compositions, that are non-toxic, non-corrosive, biodegradable acidic antimicrobial compositions that exhibit broad-spectrum antimicrobial efficacy, wherein the compositions comprise an amine oxide, such as an alkyl amine oxide, in combination with an acidulant. Beneficially, the acidic antimicrobial compositions are capable of achieving at least a 3-log microbial reduction within 5 minutes under relatively mild pH conditions. The compositions provide cleaning and sanitizing.

There is provided a biocidal composition comprising: a carrier comprising a polyurethane, a polyurethane precursor, an epoxy resin, an epoxy resin precursor, a melamine resin, or any combination thereof; a copper (I) salt; and a copper auxiliary additive different from the carrier, the copper auxiliary additive comprising a phosphite, a phosphine, or a combination thereof; and wherein the biocidal composition or the film thereof exhibits an antimicrobial efficacy of at least 3 logarithm killing after storage of the biocidal composition or the film thereof at ambient temperature and ambient relative humidity for 90 days. Further provided is a biocidal additive formulation comprising a copper (I) salt and a copper auxiliary additive wherein a biocidal composition comprising the biocidal additive formulation and a carrier or a film of the biocidal composition exhibits an antimicrobial efficacy of at least 3 logarithm killing, as measured by the EPA test.

Polycationic ingredients and organic acid chelators for use in improving the antimicrobial efficacy of known organic acid compositions at neutral to basic pH, and / or reducing the amount of organic acids needed for antimicrobial activity. Methods of boosting antimicrobial activity of organic acid compositions is achieved through adding polycationic compound(s) and organic acid chelator(s). Use of the antimicrobial compositions in products is also described.

An apparatus for coating a substrate, comprising: an antimicrobial film, comprising: a partially protonated polyethylenimine in a range of 0.1 to 5 mg per square inch; a polydiallyldimethylammonium salt; chloride counterions; first conjugate base counterions of a first organic acid, the first conjugate base counterions comprising a first mass of 0.001 to 0.1 mg per square inch; second conjugate base counterions of a second organic acid, the second conjugate base counterions comprising a second mass of 0.05 to 1 mg per square inch; and a total cationic charge of the antimicrobial film in a range of 200 to 3000 C / m2, the total cationic charge countered by anions in the antimicrobial film, the antimicrobial film comprising an antimicrobial efficacy of greater than ninety percent according to PAS 2424:1024.

The present invention pertains to a method for producing an antimicrobial composition preferably comprising piceol. Moreover, the invention relates to an antimicrobial composition comprising or consisting of piceol, preferably in an excess amount compared to picein, further plant-derived substances and optionally picein. The invention further relates to a cosmetic, personal care, household, home care, pet care or pharmaceutical product comprising said antimicrobial composition. Moreover, the invention relates to the use of a microorganism, preferably a lactobacillus species, for producing an antimicrobial composition comprising piceol from a composition, preferably a plant-extract, comprising picein. In addition, the invention relates to the use of shikimic acid for increasing the antimicrobial efficacy of piceol and / or to the use of piceol for increasing the antimicrobial efficacy of shikimic acid. Further embodiments and aspects of the invention are presented in the attached claims as well as in the description and examples below.

The present invention relates to a hard surface cleaning composition. There is a need for improved cleaning compositions for providing antimicrobial benefit in addition to cleaning benefit. The inventors have found that an aqueous composition comprising 0.01 to 20% by weight alkene amide; 0.01 to 20% by weight glycol ether of formula (I): R1O(R2O)nR3; where: —R1 is a linear or branched alkyl or phenyl group having 1 to 8 carbon atoms; —R2 is ethyl or isopropyl; -n is 1, 2, 3; —R3 is hydrogen or a linear or branched alkyl or phenyl group having 1 to 10 carbon atoms; 0.1 to 50% by weight surfactant; and at least 10% by weight water, provides significant antimicrobial benefit.

There is a very good linear relationship between the absorptivity (A) of a fabric sample to UV-Vis light and the surface concentration C of an antimicrobial agent on the fabric sample. On this basis, provided in the present invention is a method for estimating antimicrobial efficacy of a fabric sample, the method comprising: preparing antimicrobial agents of different concentrations (C), and respectively applying the antimicrobial agents to different fabric sheets to obtain fabric samples; measuring the absorptivity (A) of the fabric samples to radiation of a certain wavelength; measuring antimicrobial rates (y) of the fabric samples, to which the antimicrobial agents of different concentrations (C) are applied, against a certain microorganism; and fitting the antimicrobial rates (y) of the fabric samples and the absorptivity (A) of the fabric samples to radiation of a certain wavelength, so as to obtain a relationship between the antimicrobial rates (y) and the absorptivity (A) of the fabric samples to radiation of the wavelength, wherein the antimicrobial rate (y) of the fabric sample to be tested can be calculated by using the relationship between the antimicrobial rates (y) and the absorptivity (A) of the fabric samples to radiation of the wavelength and on the basis of the absorptivity (A1) of the fabric sample to be tested to radiation of the wavelength.

The present invention aims to provide an antimicrobial product, particularly an antimicrobial composition comprising antimicrobial active agents and solvent and preservative activity, which has antimicrobial efficacy against bacteria, fungi and yeasts at low concentrations, exhibiting broad spectrum effectiveness for gram-positive and gram-negative bacteria and high compatibility with different types of surfactants in formulations of personal hygiene, cleaning and household care products.

A thermoplastic article includes: (a) recycled thermoplastic resin, (b) antimicrobial additive, and (c) acid scavenger. The thermoplastic article has: (i) an antimicrobial efficacy characterized by a percent reduction of greater than or equal to about 99% against both S. aureus (ATCC 6538P) and E. coli (ATCC 8739), as determined according to ISO 22196; and (ii) a percent clarity of greater than or equal to about 98%, as measured at 0.060 inch (1.524 mm) thickness and according to ASTM D1003.

Substantive, biodegradable, antimicrobial—diamidoquats of Formula I, comprising a quaternary ammonium center and amide functionality and having conditioning properties along with good antimicrobial efficacy wherein, R and R1 are selected from C6 to C24. Home care, fabric care composition comprising novel compounds are effective even at lower dosage compared to other traditional conditioning compounds.wherein, R and R1 may or may not be same and are selected from C6 to C24 straight or branched chain alkyl or alkenyl residue.

The invention discloses a fish skin source antibacterial peptide, a composition and application of the fish skin source antibacterial peptide, the fish skin source antibacterial peptide is selected from FSP-1, FSP-2, FSP-3 or FSP-4, and the amino acid sequences of the FSP-1, the FSP-2, the FSP-3 and the FSP-4 are shown as SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 and SEQ ID NO: 4 in sequence. Compared with the prior art, the novel antibacterial peptide with excellent antibacterial activity is screened out by combining a fish skin proteolysis technology with an artificial intelligence prediction model. In addition, the invention further provides a composition containing the antibacterial peptide, the antibacterial peptide is combined and optimized, the antibacterial peptide has a remarkable synergistic interaction effect, and the antibacterial effect of the antibacterial peptide can be remarkably improved. The obtained antibacterial peptide and the composition have good application potential.

Disclosed herein are antimicrobial compositions having improved antimicrobial efficacy and aesthetic properties, wherein these compositions comprise at least one polyquaternium polymer, an antimicrobial agent, and an aesthetic enhancer. In particular embodiments, an antimicrobial composition comprises a quaternary ammonium salt comprising benzalkonium chloride, a first polyquaternium species, polyquaternium-6, an aesthetic enhancer selected from the group consisting of isocetyl alcohol, hexyldecanol, lauryl lactate, disodium cocoamphodiacetate, disodium cocoamphodiacetate in combination with propylene glycol, and water.

A method of making a clear, homogeneous aqueous antimicrobial composition, the method including: (a) mixing an anionic surfactant with a water-soluble cationic quaternary ammonium (QAC) surfactant in an aqueous medium under conditions effective to form an anionic-rich catanionic mixture that is clear and free of visible precipitate and retains antimicrobial efficacy, wherein: (i) total surfactant concentration is greater than 0.1 wt. %; (ii) weight or molar ratio of anionic to cationic surfactant is greater than 1; and (iii) pH of the medium is greater than or equal to 7 and adjusted with a pH-adjusting agent; and (b) adding an aqueous medium carrier comprising water and, optionally, one or more antimicrobial materials.

The present invention relates to an antimicrobial composition that not only cleans hard and soft inanimate surfaces, but also provides antimicrobial efficacy against both gram-positive and gram-negative bacteria. This is achieved by a combination of a rhamnolipid surfactant, an amino acid surfactant and a selected chelating agent.

Biocidal compositions are provided comprising a carrier, a copper (I) salt, and a copper auxiliary additive different from the carrier, which biocidal compositions have improved antimicrobial efficacy and / or total chromatic aberration in some aspects. Also provided are biocidal compositions or UV curable films thereof that exhibit a high transmittance similar to that of an otherwise identical composition or film thereof that does not contain the copper (I) salt or the copper auxiliary additive. Also provided are biocidal additive formulations wherein the molar concentration of the copper (I) salt is at least 20 mM.

A clear, homogeneous aqueous antimicrobial composition, including: (a) an anionic surfactant; (b) a water-soluble cationic quaternary ammonium (QAC) surfactant; and (c) an aqueous carrier; wherein the composition is clear and free of visible precipitate and retains antimicrobial efficacy, and wherein: (i) a total concentration of the anionic and cationic surfactants is greater than 0.1% by weight; (ii) a weight or molar ratio of the anionic surfactant to the cationic surfactant is greater than 1; and (iii) a pH of the composition is greater than or equal to 7.

Disclosed herein are antimicrobial compositions having improved antimicrobial efficacy and aesthetic properties, wherein these compositions comprise at least two polyquaternium polymers and an antimicrobial agent. In a specific embodiment, the antimicrobial composition comprises a quaternary ammonium salt in an amount of less than 1.0 wt%, a first polyquaternary ammonium salt species, namely polyquaternium-6, a second polyquaternary ammonium salt species, namely polyquaternium-22, and water.