246 results about "Hydrotrope" patented technology

Organic compositions, used neat or in concentrate, are effective in removing complex organic soils from wood, metal and other hard surfaces. The compositions comprise nonionic surfactants, silicone surfactants, hydrotropes and other optional functional materials including sequestrants. Substrates such as laundry and heavily soiled hard surfaces containing a substantial proportion of organic/inorganic soils such as greases, oils and other hard to remove soil materials are readily cleaned by the cleaner compositions of the invention.

The invention provides microemulsion pharmaceutical compositions comprising pharmaceutical actives which are hydrotropes that facilitate formation of microemulsions. The invention further provides methods of making the compositions and utilization of the compositions in liquid fill soft shell capsules including capsules having shells of non-animal derived materials (e.g. non-ADRM).

Improved hard surface cleaning compositions having an acidic pH, providing good removal of soap scum stains, and further feature low levels of irritability to the user. The compositions comprise about 0.1-10% by weight of an acid sequestrant constituent; about 0.1-10% by weight of a mixture of hydrophobic and hydrophilic solvents; about 0.001-1% by weight of a single constituent which exhibits both anionic surfactant and hydrotrope properties; about 0-20% by weight of one or more optional constituents; the balance to 100% by weight of water, wherein the aqueous hard surface cleaning composition exhibits a pH of 7 or less, especially a pH of about 5 or less. Although acidic, the improved hard surface cleaning compositions feature low irritability to the eyes and skin of consumers. The compositions also provide disinfecting effects.

The invention relates to a detergent for daily use, and specifically relates to an environment-friendly type hyperconcentration biological enzyme liquid laundry detergent and a preparation method thereof. The prepared product in the invention is mobile liquid with low viscosity, contains no phosphates, fluorescent brightening agents or alkylphenol polyoxyethylene, and has no pollution to environment. The production process for the product is simple; preparation and mass production of the product are easy; the product can be widely used for washing of various fabrics and clothing and is both applicable to hand wash and machine wash. The environment-friendly type hyperconcentration biological enzyme liquid laundry detergent comprises, by weight, 0.5 to 50 parts of fatty alcohol polyoxyethylene ether sodium sulfate-70, 0.5 to 50 parts of fatty alcohol polyoxyethylene ether-9, 0.5 to 30 parts of sodium alkylbenzene sulfonate-60, 0.2 to 15 parts of triethanolamine, 0.1 to 10 parts of sodium citrate, 0 to 5 parts of citric acid, 0 to 5 parts of aliphatic acid, 0.02 to 8 parts of biological enzyme, 0.1 to 20 parts of an enzyme stabilizer, 0.5 to 30 parts of a solvent, 0 to 15 parts of a hydrotropic agent, 0 to 5 parts of a bactericide, 0.001 to 5 parts of an antiseptic, 0 to 3 parts of essence and 1.0 to 40 parts of softened water.

Topically active compositions having enhanced effectiveness are disclosed. The compositions contain a topically active compound, an anionic surfactant, a hydric solvent, a hydrotrope, an optional cosurfactant, and water, wherein a percent saturation of the topical active compound of the composition is at least 25%. The compositions exhibit a rapid and effective topical effect, and effectively deposit the topically active compound for an effective residual effect.

The present invention provides novel pharmaceutical compositions comprising aminoalkyl phosphorothioate compounds in combination with surfactants, hydrotropes and chelating agents. The compositions are well-suited for subcutaneous administration.

An aqueous, alkaline cleaning composition for use on hard-to-clean soils, encountered in pharmaceutical, personal care, food and cosmetic manufacturing, comprising a source of alkalinity, a biodegradable surfactant system further comprising one or more surfactants, one or more hydrotropes, and a UV-analyzable surfactant, and a biodegradable chelating agent. The composition offers unique advantages of stability over the expected shelf life, low-foaming property, phosphate-free and biodegradable components, and unexpectedly enhanced antimicrobial, including virucidal, activity in one cleaning composition. The UV-analyzable surfactant allows for validation of cleaning processes using known techniques for manufacturers who are required or desire to do so.

The present invention is directed to a dual phase mouth wash composition comprising a hydrophilic phase, a hydrophobic phase, and a hydrotrope, and methods of use thereof. The hydrophilic and hydrophobic phases remain separated and form a temporary emulsion when mixed. The emulsion spontaneously reverts back to the two original phases after rest, without the formation of a emulsion.

The present invention relates to compositions comprising: (a) at least two phenolic compounds (one flavoid and one non-flavoid); (b) at least one hydrotrope; (c) at least one emulsifier; (d) a lipid-soluble antioxidant; and (e) water. The at least one hydrotrope should be present in an amount that is effective to solubilize said at least two phenolic compounds in the water phase of the composition. The at least one emulsifier should be present in an amount sufficient to create a water-in-oil or oil-in-water emulsion that is effective to solubilize the lipid-soluble antioxidant. The compositions are useful for cosmetic purposes and other uses.

A biodegradable concentrated neutral detergent composition comprises various chelate compounds, various corrosion inhibitors, an alkaline compound, at least one sequestrant, various surfactants and hydrotropes, and water. The detergent can be highly concentrated, has a good long term shelf life, and when diluted is very effective in cleaning metals such as surgical instruments and prevents corrosion resistance of the metal even in a hard water environment.

Pharmaceutical formulations comprising docetaxel, solubilizer, and α-lipoic acid, wherein the formulation is substantially free of polysorbates and polyethoxylated castor oil. The solubilizer may comprise glycofurol, acetic acid, benzyl alcohol, or ethanol. The α-lipoic acid, at certain concentrations, may impart stability and prevent degradation of docetaxel while the formulations are in storage. The formulations may be combined with a diluent, which comprises one or more hydrotropes such as tocopherol polyethylene glycol succinate and polyethylene glycol. The formulations combined with the diluent also exhibit stability after storage. Methods of administering docetaxel comprise preparing the formulation comprising docetaxel, solubilizer, and α-lipoic acid; mixing the formulation with a diluent; diluting the resulting formulation in saline, water for injection, or the like; and then injecting the formulations into patients in need thereof.

Pharmaceutical formulations comprising cabazitaxel, solubilizer, tocopherol polyethylene glycol succinate (TPGS), one or more hydrotropes, optionally one or more agents having a pK_a of about 3 to about 6, and optionally one or more antioxidizing agents, wherein the formulations are substantially free of polysorbates and polyethoxylated castor oil. The solubilizer may comprise glycofurol or ethanol. Pharmaceutical formulations may alternatively comprise cabazitaxel, solubilizer, optionally one or more agents having a pK_a of about 3 to about 6, and optionally one or more antioxidizing agents, wherein the formulations are substantially free of polysorbates and polyethoxylated castor oil. These formulations may be combined with a diluent, which comprises TPGS and one or more hydrotropes. Methods of administering the cabazitaxel formulations include combining the formulations with an infusion solution.

The invention relates to a aerosol compact hair care composition comprising: from about 23 weight % to about 45 weight % total surfactant; from about 15 weight % to about 40 weight % anionic surfactant; less than about 12 wt % of zwitterionic surfactant; from about 0.5 wt % to about 50 wt % of a viscosity reducing agent selected from the group consisting of a water-miscible solvent, hydrotrope and mixtures thereof; from about 3 wt % to about 15 wt % hydrocarbon foaming agent; wherein the ratio of zwitterionic surfactant to viscosity reducing agent is less than about 1.5.

A process for forming a low density detergent granule has the steps of providing from about 0.1% to about 6% of a hydrotrope, providing from about 22% to about 50% crutcher mix moisture, providing from about 0.2% to about 8% of a water-soluble polymer with a molecular weight of at least about 10,000 g/mol, providing from about 2% to about 20% sodium silicate having a SiO₂:NaO ratio of at least about 2r, and the balance of adjunct crutcher ingredients, mixing the hydrotrope, crutcher mix moisture, polymer, silicate, and adjunct crutcher ingredients in a crutcher to form a slurry, injecting a gas into the slurry at a pressure of from about 6,000 kPa to about 13,000 kPa, and at a rate of from about 0.01% to about 0.25% and forming the slurry into a detergent granule. The slurry is substantially free of zeolite builder and phosphate builder and the crutcher temperature is maintained at from about 40° C. to about 95° C.

Polymer composites and polymer nanocomposites are designed and manufactured by choosing surface-modified fillers having a solid surface energy matching the solid surface energy of the polymer, wherein the advancing contact angle of the polymer on the surface-modified filler is less than about 5 degrees. The fillers are surface-modified by adsorption of amorphous polymeric surfactants, consisting of either mono-modal, bimodal, or multi-modal size distribution. The surface-modified fillers of this invention display a measurable yield stress and a viscosity of about 30.000 Pa·s or less at room temperature, and comprise one or more materials selected from the group consisting of minerals, plant material, animal material, carbon fiber, graphite, amorphous carbon, carbon nanotubes, and glass fiber. This invention also provides a method for manufacturing a polymer nanocomposite which includes exfoliating an amorphous organoclay in a crystalline or semi-crystalline polymer by melt compounding the constituents in the absence of added solvents, activators, edge-modifiers, compatibilizers, or hydrotropes.

The present invention relates to detergent compositions, especially liquid, granular and tablet forms of laundry detergent compositions, that comprise improved hydrotropes, wherein the hydrotropes are organic molecules in which two polar groups are separated from each other by at least 5 aliphatic carbon atoms; liquid compositions that contain such hydrotropes have a viscosity, dilution profile and dissolution behavior that render the product effective and convenient for use as a liquid laundry detergent composition.

The invention provides a method for increasing the brightness retention of a laundered fabric after numerous washing cycles by adding to an aqueous wash liquor a quantity of a commercial laundry detergent which delivers at least 0.1 g of an optical brightener into said wash liquor, said optical brightener exhibiting instability in the presence of hypochlorite; and prior to, concurrent with, or after the commercial laundry detergent, adding a bleaching composition in an amount of at least about 0.5 g/L. The bleaching composition contains about 2.5-10% alkali metal hypochlorite; about 0.05-5% of a bleach stable surfactant bearing at least one nitrogen atom; a bleach stable anionic surfactant or a hydrotrope, wherein the ratio of (ii) to (iii) is between about 10:1 to about 1:10; and an effective amount of a source of alkalinity. The fabric is repeatedly washed and the optical brightener is enabled to deposit on the fabric to increase versus a control a Stensby whiteness measure of at least about DELTAW=4.

The invention relates to a aerosol compact hair care composition comprising: from about 23 weight % to about 45 weight % total surfactant; from about 15 weight % to about 40 weight % anionic surfactant; less than about 0.5 wt % of zwitterionic surfactant; from about 0.5 wt % to about 6 wt % of a material selected from the group consisting of a water-miscible solvent, hydrotrope and mixtures thereof; from about 3 wt % to about 15 wt % hydrocarbon foaming agent; wherein the ratio of zwitterionic surfactant to water-miscible solvent or hydrotrope is less than about 2.

Low dosage naphthenate inhibitors, such as a surfactant or hydrotrope, delivered into production fluids for contact with mixtures of oil and water, such as in a hydrocarbon producing formation, production equipment, or processing systems. Inhibitor compounds such as monophosphate esters and diphosphate esters exhibit surface-active properties that cause the inhibitors to self-associate at oil-water interfaces and inhibit interactions between organic acids in the oil with cations or cation complexes in the water. These compounds also inhibit aggregation of organic acid carboxylate salts that form when pH and pressure conditions are amenable to organic acid ionization. Preferred inhibitors do not form emulsions due to the formation of unstable mixed interface structures that result in coalescence of dispersed droplets. Naphthenate inhibitor compound dosages of less than 100 ppm can effectively inhibit naphthenate salts or other organic acid salts that can form precipitates or emulsions during crude oil production or processing.