45 results about "Bovine collagen" patented technology

The invention discloses a pressure-controlled bovine bone collagen active peptide, and belongs to the field of food. A potential ACE inhibitory peptide is rapidly screened through a bioinformatics method, the ACE inhibitory activity of the bovine bone collagen peptide is verified in combination with an in-vitro experiment, IC50 values of the screened bovine bone collagen active peptides LGALPGF, VFPGLL and AAAALGPW to ACE are 32.07 mu M, 40.41 mu M and 77.68 mu M respectively, and the peptide with the sequence is proved to have a good antihypertensive function.

The invention belongs to the field of bioactive protein peptide materials, and provides an animal-derived composite fermented skin-tendering protein peptide and a preparation method thereof. According to the invention, bovine-derived collagen and fish-derived protein are subjected to synergistic fermentation to prepare a protein peptide core, and the outer surface of the protein peptide core is coated with an edible gelatin and chondroitin sulfate composite layer; the excellent performance that a small molecule peptide core with the molecular weight being 500-1500 Da, a stable coating layer with the coating rate being 80-99%, the glycine-proline-hydroxyproline sequence collagen peptide fragment accounting for 30-60% and the pH responsive swelling ratio being 1.5-3.0 are achieved, the technical problems that traditional protein peptide is poor in stability and low in bioavailability are solved, and the protein peptide has wide application value in the field of skin care products.

The invention belongs to the technical field of food processing, and particularly relates to a product with peony peptide and ginseng peptide as main raw materials and a preparation method of the product. According to the invention, leftovers such as ginseng root hair and peony seed meal are used as raw materials, so that the production cost is greatly reduced, and the prepared product is presented in the form of a solid beverage and is convenient to carry and drink; the ginseng peptide is prepared by adopting a steam explosion and biological enzymolysis technology, the peony peptide is prepared by adopting a microbial fermentation mode, the molecular weight of the polypeptide is reduced, digestion and absorption are facilitated, meanwhile, the yield and oxidation resistance of the peptide are improved by adopting the microbial fermentation mode, the highest yield can reach 45.5%, and the highest oxidation resistance can reach 72.5%; besides, isomaltulose is also added while the bovine bone collagen peptide powder, the ginseng peptide powder and the peony peptide powder are adopted, so that the taste of the product is improved, the reconstituability of the product is improved, the fluctuation of blood sugar and insulin level is not caused after the product is taken, and the product can also be drunk by diabetics.

The present invention belongs to the technical field of medical preparations, and specifically relates to an anti-aging composition and a preparation method thereof. The anti-aging composition comprises the following raw materials in parts by weight: 5-10 parts bovine collagen tripeptide, 5-10 parts erythritol, 1-5 parts concentrated apple juice, 0.05-1 parts hydrolyzed collagen, 0.05-1 parts salmon powder, 0.05-1 parts fish maw oligopeptide, 0.05-1 parts golden bell fruit powder, 0.05-1 parts brown sugar powder, 0.05-1 parts albumin polypeptide, 0.05-1 parts sucralose, 1-5 parts anhydrous citric acid, and 55-90 parts purified water. The present invention not only supplements the collagen required by the human body, but also improves skin elasticity and scavenges free radicals.

An appetite suppressant composition may comprise at least one anorectic active ingredient; at least one of a nutritive substance, a cofactor; and optionally, an excipient. The anorectic active ingredient may comprise any one of phentermine, phendimetrazine, diethylpropion, naltrexone, and bupropion. The nutritive substance may comprise a protein source such as bovine collagen. The cofactor may comprise a chromium or selenium salt. In various embodiments, the compositions herein are provided in an oral capsule dosage form for GI-tract administration of the AAI. A method of suppressing appetite in individuals in need thereof are described.

The invention relates to a bovine bone collagen concentration prediction method and device based on spectral data, and belongs to the technical field of artificial intelligence. The method comprises the following steps: collecting near infrared spectrum data of a bovine bone sample, and constructing a training data set; processing the near infrared spectrum data of the bovine bone sample to obtain smooth spectrum data; carrying out local differential enhancement on a characteristic peak edge on the spectral data by adopting a dual-channel characteristic enhancement mechanism, and carrying out global transformation to obtain a global transformation characteristic value; constructing a bovine bone collagen concentration prediction model which comprises a cross-layer spectrum section attention residual module, a spectrum-concentration correlation gating module, a bovine bone collagen concentration prediction module and a loss function; inputting the global transformation characteristic value into a bovine bone collagen concentration prediction model, and training and optimizing the model; and processing to-be-detected data, and inputting the processed to-be-detected data into the trained model to obtain a prediction result of the concentration of the bovine bone collagen. According to the method, the accuracy of predicting the concentration of the bovine bone collagen can be improved.

The invention provides an anti-freezing polypeptide derived from Yanbian cattle collagen, the polypeptide has obvious protection and improvement effects on cattle embryo freezing quality, and the amino acid sequence of the polypeptide is shown as SEQ ID NO.1 or 2. On the basis, the invention provides a bovine embryo vitrification freezing kit using the polypeptide and a freezing method of the bovine embryo vitrification freezing kit. The kit can effectively protect the embryo, so that the embryo to be preserved is put into liquid nitrogen for cryopreservation, the operation is simple, and expensive instruments and equipment are not needed.

The present invention discloses a glucosamine chondroitin composition and a preparation method thereof, belonging to the field of health care products. The composition comprises a turmeric extract, a drynaria extract, an eucommia extract, a rehmannia extract, vitamin K, bovine collagen peptides, chondroitin sulfate, glucosamine hydrochloride, and lactic acid calcium. The present invention achieves an excellent bone density-enhancing effect by compounding the turmeric extract, the drynaria extract, the eucommia extract, the rehmannia extract, vitamin K, bovine collagen peptides, chondroitin sulfate, glucosamine hydrochloride, and lactic acid calcium.

The application provides a preparation method and application of bovine collagen peptide, and belongs to the technical field of collagen peptide; the preparation method comprises the steps of freeze-thaw-microwave treatment, alkaline hydrolysis, enzyme hydrolysis 1, enzyme hydrolysis 2, enzyme hydrolysis 3, enzyme hydrolysis 4 and antiseptic filtration; in the freeze-thaw-microwave treatment step, bovine skin powder is added into a mixed solution, stirred uniformly, and then soaked for 15-20 min; the mixed solution is placed in a sealed container for freeze-thaw treatment, frozen at-24 to-20 DEG C for 5-6 h, naturally thawed, and then the freeze-thaw treatment is repeated for 1-2 times; the water content is controlled to be 50-52 wt %, and wet material is obtained; the wet material is placed into a microwave device for microwave treatment, and the temperature of the wet material is controlled to be lower than 55 DEG C, so that freeze-thaw-microwave treated bovine skin powder is obtained; the product obtained by the method has high polypeptide content, and when the product is applied to soybeans, potatoes and lettuce, the yield and quality can be effectively improved.

An appetite suppressant composition may comprise at least one anorectic active ingredient; at least one of a nutritive substance, a cofactor; and optionally, an excipient. The anorectic active ingredient may comprise any one of phentermine, phendimetrazine, diethylpropion, naltrexone, and bupropion. The nutritive substance may comprise a protein source such as bovine collagen. The cofactor may comprise a chromium or selenium salt. In various embodiments, the compositions herein are provided in an oral capsule dosage form for GI-tract administration of the AAI. A method of suppressing appetite in individuals in need thereof are described.

The invention belongs to the technical field of medical preparations, and particularly relates to an anti-aging composition and a preparation method thereof. The anti-aging composition is prepared from the following raw materials in parts by weight: 5 to 10 parts of bovine collagen tripeptide, 5 to 10 parts of erythritol, 1 to 5 parts of concentrated apple juice, 0.05 to 1 part of hydrolyzed collagen, 0.05 to 1 part of trout essence powder, 0.05 to 1 part of fish maw oligopeptide, 0.05 to 1 part of szechwan chinaberry fruit powder, 0.05 to 1 part of brown sugar powder, 0.05 to 1 part of albumin polypeptide, 0.01 to 0.05 part of sucralose, 1 to 5 parts of anhydrous citric acid and 55 to 90 parts of purified water. According to the present invention, the collagen required by the human body can be supplemented, the skin elasticity can be improved, and the free radical can be removed.

The present invention relates to a composition used as a dietary supplement to produce short-chain peptides related to skin appearance in the digestive tract, which comprises at least the following components: bovine collagen peptides with an average molecular weight of 2000Da, characterized by high sequence homology with human type I collagen α-1, human type I collagen α-2 and human type III collagen α-1, and a total sequence coverage of more than 90% for human type I collagen α-1 and human type I collagen α-2, and an aqueous extract of acerola fruit (Malpighia punicifolia), characterized by the presence of soluble dietary fiber and high uronic acid content in addition to standardized vitamin C content. The present invention is particularly suitable as a dietary supplement for maintaining healthy skin.

The present application relates to the field of food processing and biotechnology, and in particular to a glycosylated bovine bone collagen antioxidant peptide, a preparation method and application thereof. The glycosylated bovine bone collagen antioxidant peptide is prepared by enzymolysis and Maillard reaction using Yanbian yellow cattle bone as raw material, and the core antioxidant peptide sequence is shown as SEQ ID NO: 1-7. The present application uses Maillard reaction to endow the Yanbian yellow cattle bone collagen peptide with excellent caramel aroma, meat aroma and salty and fresh characteristics, and the antioxidant mechanism of the antioxidant peptide is jointly confirmed through multiscale simulation and in vitro experiment. Therefore, the present application integrates a set of high-value utilization route of bovine bone by using enzymolysis and Maillard modification, realizes the transformation of waste into treasure of slaughter by-products, and meets the green and sustainable development concept.

The invention discloses a programmed controllable slow-release bionic spinal cord graft and a preparation method and application thereof, and belongs to the field of medical biomaterials.The preparation method comprises the steps that a micro-nano oriented fiber scaffold with a groove is synthesized on the basis of recombinant NT3, silk fibroin, bovine collagen and a neurotrophic factor NGF; the programmed controllable slow-release bionic spinal cord graft is jointly constructed by combining an acellular matrix and an exosome derived from human umbilical cord mesenchymal stem cells with a programmed slow-release system of GelMA drug-loaded microspheres containing cyclosporine a; multiple technologies such as bionic tissue engineering, a micro-fluidic technology, a drug-loaded microsphere controllable slow-release technology, an acellular matrix and exosome are combined, spinal cord injury repair is facilitated, good biocompatibility is achieved, nerve axons are promoted to grow in an oriented mode, immune regulation can be given in the early stage of spinal cord injury, the nerve regeneration microenvironment after spinal cord injury is improved, and the nerve regeneration effect is improved. The method is beneficial to nerve regeneration and functional reconstruction after spinal cord injury.

The invention relates to the technical field of nutritional supplements, and particularly discloses nutritional peptide powder based on exercise recovery, endurance improvement and energy control and a production process thereof.The nutritional peptide powder mainly comprises bovine bone collagen peptide powder, amino acid, crystalline fructose, crystalline trehalose, pure coconut powder, whole milk powder, oat powder and flaxseed powder. The formula is adjusted according to different requirements of exercise recovery, endurance improvement and energy control, crystalline fructose and crystalline trehalose are used as low glycemic index sugar sources, energy can be stably released, exercise performance can be improved, rapid exhaustion after short-time consumption of energy is avoided, medium-chain fatty acid is provided by adding pure coconut powder, and the effect of improving exercise performance is achieved. Stable energy support is provided for long-time exercise, and energy intake is effectively controlled through the combination of the whole milk powder, the oat powder and the flaxseed powder. The whole formula ensures exercise recovery and endurance improvement, realizes energy control, is suitable for different exercise crowds, and provides multifunctional, efficient and healthy nutrition support.

In some aspects, the disclosure relates to a composition including niacinamide and polypodium leucotomos extract, optionally with additional photoprotective ingredients including ascorbic acid, optionally biotin, astaxanthin, bovine collagen peptides, L-glutathione, hyaluronic acid, and inositol. The composition provides rapid and measurable photoprotection, reducing UV-induced erythema by approximately 60-68% when administered 1-2 hours prior to UV exposure. Clinical studies demonstrate significant increases in minimal erythema dose (MED) with effects persisting for at least 24 hours following a single oral administration. The composition exhibits excellent formulation characteristics including superior mixability, clarity, and palatability when formulated as a beverage powder.

The invention relates to a selenium-rich organic Chinese wolfberry tablet and a preparation method thereof, belongs to the technical field of food processing, and particularly relates to the selenium-rich organic Chinese wolfberry tablet and the preparation method thereof. The invention provides a selenium-rich organic Chinese wolfberry tablet and a preparation method thereof. The selenium-rich organic Chinese wolfberry tablet is prepared from selenium-rich auricularia fuscosuccinea, selenium-rich organic Chinese wolfberry, erythritol, maltodextrin, resistant dextrin, bovine bone collagen peptide, calf thymosin peptide and magnesium stearate as raw materials. The preparation method of the selenium-rich organic Chinese wolfberry tablets comprises the following steps: taking selenium-rich auricularia fuscosuccinea, selenium-rich organic Chinese wolfberry, erythritol, maltodextrin, resistant dextrin, bovine bone collagen peptide, calf thymosin peptide and magnesium stearate as raw materials, crushing the raw materials into powder, mixing ingredients, carrying out wet mixing, drying, carrying out swing granulation, and tabletting to obtain the selenium-rich organic Chinese wolfberry tablets. The preparation method of the selenium-rich organic Chinese wolfberry tablets is simple and easy to implement, and selenium nutrients needed by human bodies can be safely and effectively supplemented.

The present invention relates to a composite solid beverage for alleviating and / or improving osteoporosis and a preparation method and application thereof, belonging to the technical field of health food. The composite solid beverage of the present invention comprises the following components: cucumber seed powder, walnut powder, kudzu root powder, elderberry powder, composite grain powder, resistant dextrin, bovine bone collagen peptide, type II collagen peptide, milk calcium, composite vitamins, composite minerals, sweeteners, edible flavors, xanthan gum, and sodium carboxymethyl cellulose; wherein the composite vitamins include VA, VB1, VB6, VB 12 , VC, VD, VE, folic acid and pantothenic acid; and composite minerals include iron and magnesium. The composite solid beverage of the present invention can inhibit bone absorption and promote the formation of normal bone mass, and has the characteristics of good absorption effect, significant relief and / or improvement effect and no side effects.

Provided herein is an exercise supporting nutritional supplement with an associated delivery platform, method, and system. As disclosed the exercise supporting nutritional supplement may comprise some or all of Agmatine Sulfate, Betaine Anhydrous, Choline (as Choline Bitartrate), Citrulline, Creatine Monohydrate, Beta Alanine, L-Tyrosine, Choline Bitartrate, Bovine Collagen, Caffeine Anhydrous, Pink Himalayan Salt, and Black Pepper Extract.

The present application belongs to the technical field of biological medicine, and particularly relates to a composition for improving cognitive function, a preparation method, products and applications thereof. The composition is prepared from soybean meal powder, whey protein peptide powder and bovine collagen peptide powder in a mass ratio of 1:3:2 as a peptide source raw material, in combination with AMY001, Lactobacillus plantarum LP-90 and Clostridium butyricum (3:1:1) composite strains, through Bacillus amyloliquefaciens enzyme production self-digestion, peptide-bacteria anaerobic synergistic fermentation and sodium alginate-HPMC-CPP composite carrier embedding. The composition can work synergistically through multiple mechanisms such as clearing hippocampal Aβ1-42 protein, increasing BDNF content and inhibiting IL-6 expression, has high memory improvement rate and Aβ1-42 clearance rate, and can significantly repair cognitive impairment. The composition has high stability and bioavailability, the preparation process is controllable, and is suitable for the development of drugs for preventing or assisting in improving cognitive impairment related diseases.

The invention relates to the field of collagen peptides, in particular to a bovine collagen composition with antioxidant activity and a preparation method of the bovine collagen composition, and solves the problems that collagen is easily affected by the environment in the process of being prepared into dry powder and is reduced, oxidative substances are broken, disulfide bonds are mistakenly connected, and the stability of the collagen is poor. According to the present invention, the problems that the three-helix structure of the collagen is damaged due to the disruption of the collagen and the biological activity of the collagen is reduced in the prior art are solved, and the collagen composition comprises the following components in parts by weight: 100-200 parts of a collagen precipitation body, 10-20 parts of trehalose, 5-10 parts of oxidized glutathione, and 20-40 parts of an iodoacetamide sustained-release body, the iodoacetamide sustained-release body comprises iodoacetamide and a sustained-release carrier, and the weight ratio of the iodoacetamide to the sustained-release carrier is (1-2): 10; the slow-release carrier is one of chitosan, lipidosome or sodium alginate. The collagen with high biological activity can be obtained, has extremely high oxidation resistance, and is few in misfolding and high in activity in an unsuitable environment.

The invention discloses a method for extracting bovine bone collagen and its application, belonging to the technical field of collagen extraction. The extraction method comprises 7 steps of pretreatment, defatting, decalcification, acid treatment, enzymolysis, crude product preparation and purification, wherein the best test conditions and reagents are selected for each step, and the bovine bone is pretreated by defatting and decalcifying in a specific method, effectively removing fat and inorganic mineral calcium salts, and protecting the activity of collagen components to the maximum extent, improving the extraction rate of collagen and product quality; in addition, the method of combining enzymolysis and acid treatment is adopted to adjust the best reaction conditions, and obtain highly active collagen to the maximum extent, and the prepared high-purity and high-quality bovine bone collagen can be further applied to the fields of health food and cosmetics.

The utility model discloses a drying device for producing bovine collagen peptide, which belongs to the technical field of bovine collagen peptide production, and comprises a drying machine body, a drying component and a telescopic component; the drying machine body comprises a machine body, a feeding cover, a discharge pipe and a heating block; the feeding cover is hingedly matched with the machine body; the discharge pipe is fixedly arranged on the circumferential surface of the machine body; a plurality of heating blocks are fixedly arranged on the inner wall of the machine body in an annular array; the drying component is arranged on the machine body; the drying component comprises a supporting frame, a driving motor, a fixed cylinder, a movable cylinder, a limiting groove, a limiting block, a stirring rod and a stirring piece; the supporting frame is fixedly arranged on the machine body; the driving motor is fixedly arranged on the supporting frame; the fixed cylinder is fixedly arranged on the machine body; the movable cylinder is arranged in the fixed cylinder; the limiting groove is provided on the movable cylinder; the limiting block is arranged in the limiting groove; the stirring rod is fixedly arranged on the movable cylinder; a plurality of stirring pieces are evenly fixedly arranged on the stirring rod; the drying device for producing bovine collagen peptide has a compact structure, high drying efficiency and long service life.

The invention relates to the technical field of fibers, and provides a high-strength bio-based milk protein fiber and a preparation method thereof.The high-strength bio-based milk protein fiber is prepared from, by weight, 70-80 parts of cow cheese protein, 6-10 parts of bovine bone collagen, 1-5 parts of polyvinyl alcohol, 2-5 parts of modified cellulose nanofiber, 1-2.5 parts of cross-linking agent, 1.5-3 parts of defoaming agent and 210-250 parts of water; wherein the modified cellulose nanofibers are obtained by modifying cellulose nanofibers with an aromatic substituted oxygen-containing compound.

The application discloses a kind of Bose factor shampoo and preparation method thereof, wherein Bose factor shampoo includes the following components: water 60-80 parts, surfactant component 15-40 parts, thickening stabilizer 1-8 parts, functional ingredient component 5-20 parts, wherein, the functional ingredient component includes: tea extract 1-5 parts, hydrolyzed silk 0.1-1 part, malt oligosaccharide glucoside 0.5-2 parts, hydroxyethyl urea 0.01-0.1 part, hydroxypropyl tetrahydro pyran triol 0.1-1 part, the surfactant component includes sodium laureth sulfate, cocamide MEA, sodium lauroamphoacetate, sodium lauroylsarcosinate, sodium cocamidopropylate, cocamidopropyl betaine, the application realizes multiple care effect on hair by scientific compounding and synergistic effect of specific component, excellent technical effect is obtained in cleaning power, mildness, nourishing repair, enhanced elasticity and oil control relief, with remarkable creativity and industrial application value.

The present application relates to the technical field of traditional Chinese medicine, and provides a traditional Chinese medicine composition capable of promoting bone fracture healing, which comprises the following components in parts by weight: Cordyceps militaris 25-35 parts, raspberry 20-25 parts, cucumber seed 15-22 parts, perilla seed 12-18 parts, radish seed 10-15 parts, bovine collagen peptide powder 8-12 parts, angelica 5-10 parts, and safflower 1-5 parts. The technical scheme solves the problem of poor effect of traditional Chinese medicine composition in promoting bone fracture healing.

The invention discloses a preparation method of a low-fat healthy beef sausage containing bovine-derived collagen and wheat germ powder. The preparation method comprises the following steps: (1) extracting the bovine-derived collagen; (2) preparing a collagen / wheat germ powder / ice pre-emulsion; (3) making the beef sausages; and (4) determination of texture, color and sensory evaluation of the beef sausage. According to the preparation method disclosed by the invention, bovine-derived collagen in cow leather is extracted by combining enzymolysis of compound protease with an ultrasonic-assisted traditional water boiling method, and after the bovine collagen is obtained, the bovine collagen is compounded with wheat germ powder and ice cubes to prepare a pre-emulsion which is added into beef sausages to replace beef tallow which is originally added into the beef sausages; the healthy beef sausages without adding oil to strengthen dietary fibers are prepared, and the texture and color of the beef sausages are close to those of traditional beef sausages. The bovine-derived collagen is extracted from edible parts of cow leather, and the wheat germ powder is a food source rich in dietary fibers and is safe and harmless.

An appetite suppressant composition may comprise at least one anorectic active ingredient; at least one of a nutritive substance, a cofactor; and optionally, an excipient. The anorectic active ingredient may comprise any one of phentermine, phendimetrazine, diethylpropion, naltrexone, and bupropion. The nutritive substance may comprise a protein source such as bovine collagen. The cofactor may comprise a chromium or selenium salt. In various embodiments, the compositions herein are provided in an oral capsule dosage form for GI-tract administration of the AAI. A method of suppressing appetite in individuals in need thereof are described.

The present invention relates to a collagen multifilament fiber and a preparation method and application thereof. The preparation method comprises the following steps: step (1), fully swelling bovine collagen in deionized water, adding a water-soluble crosslinking agent, and stirring at room temperature for 2 to 8 hours to obtain a collagen colloid dispersion; step (2), filtering the collagen colloid dispersion through a filter screen, and performing a centrifugal degassing treatment to obtain a collagen spinning solution; step (3), squeezing the collagen spinning solution into a coagulation bath through a wet spinning device, and obtaining collagen multifilament fibers through traction, a washing bath, stretching and drying. The preparation method of the present invention can effectively prevent the occurrence of strand adhesion in the collagen multifilament fibers, realize industrial production, and the obtained collagen multifilament fibers have excellent mechanical properties and can be applied in the textile field and the medical field.

An appetite suppressant composition may comprise at least one anorectic active ingredient; at least one of a nutritive substance, a cofactor; and optionally, an excipient. The anorectic active ingredient may comprise any one of phentermine, phendimetrazine, diethylpropion, naltrexone, and bupropion. The nutritive substance may comprise a protein source such as bovine collagen. The cofactor may comprise a chromium or selenium salt. In various embodiments, the compositions herein are provided in an oral capsule dosage form for GI-tract administration of the AAI. A method of suppressing appetite in individuals in need thereof are described.