35 results about "Bovine collagen" patented technology

The invention discloses a pressure-controlled bovine bone collagen active peptide, and belongs to the field of food. A potential ACE inhibitory peptide is rapidly screened through a bioinformatics method, the ACE inhibitory activity of the bovine bone collagen peptide is verified in combination with an in-vitro experiment, IC50 values of the screened bovine bone collagen active peptides LGALPGF, VFPGLL and AAAALGPW to ACE are 32.07 mu M, 40.41 mu M and 77.68 mu M respectively, and the peptide with the sequence is proved to have a good antihypertensive function.

The invention belongs to the field of bioactive protein peptide materials, and provides an animal-derived composite fermented skin-tendering protein peptide and a preparation method thereof. According to the invention, bovine-derived collagen and fish-derived protein are subjected to synergistic fermentation to prepare a protein peptide core, and the outer surface of the protein peptide core is coated with an edible gelatin and chondroitin sulfate composite layer; the excellent performance that a small molecule peptide core with the molecular weight being 500-1500 Da, a stable coating layer with the coating rate being 80-99%, the glycine-proline-hydroxyproline sequence collagen peptide fragment accounting for 30-60% and the pH responsive swelling ratio being 1.5-3.0 are achieved, the technical problems that traditional protein peptide is poor in stability and low in bioavailability are solved, and the protein peptide has wide application value in the field of skin care products.

The invention belongs to the technical field of food processing, and particularly relates to a product with peony peptide and ginseng peptide as main raw materials and a preparation method of the product. According to the invention, leftovers such as ginseng root hair and peony seed meal are used as raw materials, so that the production cost is greatly reduced, and the prepared product is presented in the form of a solid beverage and is convenient to carry and drink; the ginseng peptide is prepared by adopting a steam explosion and biological enzymolysis technology, the peony peptide is prepared by adopting a microbial fermentation mode, the molecular weight of the polypeptide is reduced, digestion and absorption are facilitated, meanwhile, the yield and oxidation resistance of the peptide are improved by adopting the microbial fermentation mode, the highest yield can reach 45.5%, and the highest oxidation resistance can reach 72.5%; besides, isomaltulose is also added while the bovine bone collagen peptide powder, the ginseng peptide powder and the peony peptide powder are adopted, so that the taste of the product is improved, the reconstituability of the product is improved, the fluctuation of blood sugar and insulin level is not caused after the product is taken, and the product can also be drunk by diabetics.

The present invention belongs to the technical field of medical preparations, and specifically relates to an anti-aging composition and a preparation method thereof. The anti-aging composition comprises the following raw materials in parts by weight: 5-10 parts bovine collagen tripeptide, 5-10 parts erythritol, 1-5 parts concentrated apple juice, 0.05-1 parts hydrolyzed collagen, 0.05-1 parts salmon powder, 0.05-1 parts fish maw oligopeptide, 0.05-1 parts golden bell fruit powder, 0.05-1 parts brown sugar powder, 0.05-1 parts albumin polypeptide, 0.05-1 parts sucralose, 1-5 parts anhydrous citric acid, and 55-90 parts purified water. The present invention not only supplements the collagen required by the human body, but also improves skin elasticity and scavenges free radicals.

An appetite suppressant composition may comprise at least one anorectic active ingredient; at least one of a nutritive substance, a cofactor; and optionally, an excipient. The anorectic active ingredient may comprise any one of phentermine, phendimetrazine, diethylpropion, naltrexone, and bupropion. The nutritive substance may comprise a protein source such as bovine collagen. The cofactor may comprise a chromium or selenium salt. In various embodiments, the compositions herein are provided in an oral capsule dosage form for GI-tract administration of the AAI. A method of suppressing appetite in individuals in need thereof are described.

The invention relates to a bovine bone collagen concentration prediction method and device based on spectral data, and belongs to the technical field of artificial intelligence. The method comprises the following steps: collecting near infrared spectrum data of a bovine bone sample, and constructing a training data set; processing the near infrared spectrum data of the bovine bone sample to obtain smooth spectrum data; carrying out local differential enhancement on a characteristic peak edge on the spectral data by adopting a dual-channel characteristic enhancement mechanism, and carrying out global transformation to obtain a global transformation characteristic value; constructing a bovine bone collagen concentration prediction model which comprises a cross-layer spectrum section attention residual module, a spectrum-concentration correlation gating module, a bovine bone collagen concentration prediction module and a loss function; inputting the global transformation characteristic value into a bovine bone collagen concentration prediction model, and training and optimizing the model; and processing to-be-detected data, and inputting the processed to-be-detected data into the trained model to obtain a prediction result of the concentration of the bovine bone collagen. According to the method, the accuracy of predicting the concentration of the bovine bone collagen can be improved.

The present invention discloses a glucosamine chondroitin composition and a preparation method thereof, belonging to the field of health care products. The composition comprises a turmeric extract, a drynaria extract, an eucommia extract, a rehmannia extract, vitamin K, bovine collagen peptides, chondroitin sulfate, glucosamine hydrochloride, and lactic acid calcium. The present invention achieves an excellent bone density-enhancing effect by compounding the turmeric extract, the drynaria extract, the eucommia extract, the rehmannia extract, vitamin K, bovine collagen peptides, chondroitin sulfate, glucosamine hydrochloride, and lactic acid calcium.

The application provides a preparation method and application of bovine collagen peptide, and belongs to the technical field of collagen peptide; the preparation method comprises the steps of freeze-thaw-microwave treatment, alkaline hydrolysis, enzyme hydrolysis 1, enzyme hydrolysis 2, enzyme hydrolysis 3, enzyme hydrolysis 4 and antiseptic filtration; in the freeze-thaw-microwave treatment step, bovine skin powder is added into a mixed solution, stirred uniformly, and then soaked for 15-20 min; the mixed solution is placed in a sealed container for freeze-thaw treatment, frozen at-24 to-20 DEG C for 5-6 h, naturally thawed, and then the freeze-thaw treatment is repeated for 1-2 times; the water content is controlled to be 50-52 wt %, and wet material is obtained; the wet material is placed into a microwave device for microwave treatment, and the temperature of the wet material is controlled to be lower than 55 DEG C, so that freeze-thaw-microwave treated bovine skin powder is obtained; the product obtained by the method has high polypeptide content, and when the product is applied to soybeans, potatoes and lettuce, the yield and quality can be effectively improved.

The present application relates to the field of food processing and biotechnology, and in particular to a glycosylated bovine bone collagen antioxidant peptide, a preparation method and application thereof. The glycosylated bovine bone collagen antioxidant peptide is prepared by enzymolysis and Maillard reaction using Yanbian yellow cattle bone as raw material, and the core antioxidant peptide sequence is shown as SEQ ID NO: 1-7. The present application uses Maillard reaction to endow the Yanbian yellow cattle bone collagen peptide with excellent caramel aroma, meat aroma and salty and fresh characteristics, and the antioxidant mechanism of the antioxidant peptide is jointly confirmed through multiscale simulation and in vitro experiment. Therefore, the present application integrates a set of high-value utilization route of bovine bone by using enzymolysis and Maillard modification, realizes the transformation of waste into treasure of slaughter by-products, and meets the green and sustainable development concept.

The invention relates to the technical field of nutritional supplements, and particularly discloses nutritional peptide powder based on exercise recovery, endurance improvement and energy control and a production process thereof.The nutritional peptide powder mainly comprises bovine bone collagen peptide powder, amino acid, crystalline fructose, crystalline trehalose, pure coconut powder, whole milk powder, oat powder and flaxseed powder. The formula is adjusted according to different requirements of exercise recovery, endurance improvement and energy control, crystalline fructose and crystalline trehalose are used as low glycemic index sugar sources, energy can be stably released, exercise performance can be improved, rapid exhaustion after short-time consumption of energy is avoided, medium-chain fatty acid is provided by adding pure coconut powder, and the effect of improving exercise performance is achieved. Stable energy support is provided for long-time exercise, and energy intake is effectively controlled through the combination of the whole milk powder, the oat powder and the flaxseed powder. The whole formula ensures exercise recovery and endurance improvement, realizes energy control, is suitable for different exercise crowds, and provides multifunctional, efficient and healthy nutrition support.

In some aspects, the disclosure relates to a composition including niacinamide and polypodium leucotomos extract, optionally with additional photoprotective ingredients including ascorbic acid, optionally biotin, astaxanthin, bovine collagen peptides, L-glutathione, hyaluronic acid, and inositol. The composition provides rapid and measurable photoprotection, reducing UV-induced erythema by approximately 60-68% when administered 1-2 hours prior to UV exposure. Clinical studies demonstrate significant increases in minimal erythema dose (MED) with effects persisting for at least 24 hours following a single oral administration. The composition exhibits excellent formulation characteristics including superior mixability, clarity, and palatability when formulated as a beverage powder.

Provided herein is an exercise supporting nutritional supplement with an associated delivery platform, method, and system. As disclosed the exercise supporting nutritional supplement may comprise some or all of Agmatine Sulfate, Betaine Anhydrous, Choline (as Choline Bitartrate), Citrulline, Creatine Monohydrate, Beta Alanine, L-Tyrosine, Choline Bitartrate, Bovine Collagen, Caffeine Anhydrous, Pink Himalayan Salt, and Black Pepper Extract.

The present application belongs to the technical field of biological medicine, and particularly relates to a composition for improving cognitive function, a preparation method, products and applications thereof. The composition is prepared from soybean meal powder, whey protein peptide powder and bovine collagen peptide powder in a mass ratio of 1:3:2 as a peptide source raw material, in combination with AMY001, Lactobacillus plantarum LP-90 and Clostridium butyricum (3:1:1) composite strains, through Bacillus amyloliquefaciens enzyme production self-digestion, peptide-bacteria anaerobic synergistic fermentation and sodium alginate-HPMC-CPP composite carrier embedding. The composition can work synergistically through multiple mechanisms such as clearing hippocampal Aβ1-42 protein, increasing BDNF content and inhibiting IL-6 expression, has high memory improvement rate and Aβ1-42 clearance rate, and can significantly repair cognitive impairment. The composition has high stability and bioavailability, the preparation process is controllable, and is suitable for the development of drugs for preventing or assisting in improving cognitive impairment related diseases.

The invention relates to the technical field of fibers, and provides a high-strength bio-based milk protein fiber and a preparation method thereof.The high-strength bio-based milk protein fiber is prepared from, by weight, 70-80 parts of cow cheese protein, 6-10 parts of bovine bone collagen, 1-5 parts of polyvinyl alcohol, 2-5 parts of modified cellulose nanofiber, 1-2.5 parts of cross-linking agent, 1.5-3 parts of defoaming agent and 210-250 parts of water; wherein the modified cellulose nanofibers are obtained by modifying cellulose nanofibers with an aromatic substituted oxygen-containing compound.

The application discloses a kind of Bose factor shampoo and preparation method thereof, wherein Bose factor shampoo includes the following components: water 60-80 parts, surfactant component 15-40 parts, thickening stabilizer 1-8 parts, functional ingredient component 5-20 parts, wherein, the functional ingredient component includes: tea extract 1-5 parts, hydrolyzed silk 0.1-1 part, malt oligosaccharide glucoside 0.5-2 parts, hydroxyethyl urea 0.01-0.1 part, hydroxypropyl tetrahydro pyran triol 0.1-1 part, the surfactant component includes sodium laureth sulfate, cocamide MEA, sodium lauroamphoacetate, sodium lauroylsarcosinate, sodium cocamidopropylate, cocamidopropyl betaine, the application realizes multiple care effect on hair by scientific compounding and synergistic effect of specific component, excellent technical effect is obtained in cleaning power, mildness, nourishing repair, enhanced elasticity and oil control relief, with remarkable creativity and industrial application value.

The present application relates to the technical field of traditional Chinese medicine, and provides a traditional Chinese medicine composition capable of promoting bone fracture healing, which comprises the following components in parts by weight: Cordyceps militaris 25-35 parts, raspberry 20-25 parts, cucumber seed 15-22 parts, perilla seed 12-18 parts, radish seed 10-15 parts, bovine collagen peptide powder 8-12 parts, angelica 5-10 parts, and safflower 1-5 parts. The technical scheme solves the problem of poor effect of traditional Chinese medicine composition in promoting bone fracture healing.

The invention discloses a preparation method of a low-fat healthy beef sausage containing bovine-derived collagen and wheat germ powder. The preparation method comprises the following steps: (1) extracting the bovine-derived collagen; (2) preparing a collagen / wheat germ powder / ice pre-emulsion; (3) making the beef sausages; and (4) determination of texture, color and sensory evaluation of the beef sausage. According to the preparation method disclosed by the invention, bovine-derived collagen in cow leather is extracted by combining enzymolysis of compound protease with an ultrasonic-assisted traditional water boiling method, and after the bovine collagen is obtained, the bovine collagen is compounded with wheat germ powder and ice cubes to prepare a pre-emulsion which is added into beef sausages to replace beef tallow which is originally added into the beef sausages; the healthy beef sausages without adding oil to strengthen dietary fibers are prepared, and the texture and color of the beef sausages are close to those of traditional beef sausages. The bovine-derived collagen is extracted from edible parts of cow leather, and the wheat germ powder is a food source rich in dietary fibers and is safe and harmless.

An appetite suppressant composition may comprise at least one anorectic active ingredient; at least one of a nutritive substance, a cofactor; and optionally, an excipient. The anorectic active ingredient may comprise any one of phentermine, phendimetrazine, diethylpropion, naltrexone, and bupropion. The nutritive substance may comprise a protein source such as bovine collagen. The cofactor may comprise a chromium or selenium salt. In various embodiments, the compositions herein are provided in an oral capsule dosage form for GI-tract administration of the AAI. A method of suppressing appetite in individuals in need thereof are described.

The present invention relates to a collagen multifilament fiber and a preparation method and application thereof. The preparation method comprises the following steps: step (1), fully swelling bovine collagen in deionized water, adding a water-soluble crosslinking agent, and stirring at room temperature for 2 to 8 hours to obtain a collagen colloid dispersion; step (2), filtering the collagen colloid dispersion through a filter screen, and performing a centrifugal degassing treatment to obtain a collagen spinning solution; step (3), squeezing the collagen spinning solution into a coagulation bath through a wet spinning device, and obtaining collagen multifilament fibers through traction, a washing bath, stretching and drying. The preparation method of the present invention can effectively prevent the occurrence of strand adhesion in the collagen multifilament fibers, realize industrial production, and the obtained collagen multifilament fibers have excellent mechanical properties and can be applied in the textile field and the medical field.

An appetite suppressant composition may comprise at least one anorectic active ingredient; at least one of a nutritive substance, a cofactor; and optionally, an excipient. The anorectic active ingredient may comprise any one of phentermine, phendimetrazine, diethylpropion, naltrexone, and bupropion. The nutritive substance may comprise a protein source such as bovine collagen. The cofactor may comprise a chromium or selenium salt. In various embodiments, the compositions herein are provided in an oral capsule dosage form for GI-tract administration of the AAI. A method of suppressing appetite in individuals in need thereof are described.

The invention belongs to the field of dietary food, and particularly discloses a dietary protein human supplement easy to absorb by human body and a preparation method thereof, the dietary protein human supplement comprises the following components by mass percentage: 30%-45% of hydrolyzed whey protein powder, 20%-25% of soybean oligopeptide, 15%-22% of bovine bone collagen peptide, and 8%-15% of composite active peptide; the composite active peptide comprises at least one first type of peptide for activating a small intestine oligopeptide transporter PEPT1 and at least one second type of peptide for inhibiting the activity of dipeptidyl peptidase-IV; according to the invention, a PEPT1 transporter is directly utilized for absorption through the small molecule peptide, the composite active peptide activates PEPT1 and inhibits DPP-IV at the same time, not only is peptide fragment transport promoted, but also degradation of the peptide fragment is reduced, and the synergistic effect of bovine bone collagen peptide high hydroxyproline and soybean peptide high branched chain amino acid is utilized, so that the muscle protein synthesis rate is increased and activated, and the protein absorption efficiency is greatly improved.

The invention discloses a bovine collagen peptide for promoting bone health as well as a production method and application thereof, and belongs to the technical field of collagen production. The preparation method comprises the following steps: adding water, neutral protease and alkaline protease into degreased cattle bone powder, heating to 50-60 DEG C to obtain an enzymolysis sample solution, applying low-voltage alternating current to the enzymolysis sample solution, carrying out auxiliary enzymolysis at 50-60 DEG C, carrying out enzyme deactivation treatment after enzymolysis, centrifuging the treated enzymolysis solution to remove precipitates, filtering supernate by adopting an ultrafiltration membrane, concentrating, and freeze-drying to obtain the cattle bone meal. The bovine collagen peptide capable of promoting bone health is obtained. According to the preparation method disclosed by the invention, the low-voltage alternating current is cooperated with the enzymolysis step, so that acidic amino acids containing glutamic acid (Glu) and aspartic acid (Asp) can be promoted to be separated from macromolecular collagen, the high-content micromolecular bovine collagen peptide containing glutamic acid and aspartic acid is obtained, and the bovine collagen peptide can better promote proliferation of MC3T3-E1 cells and promote bone repair.

The invention belongs to the technical field of collagen extraction, and particularly relates to bovine collagen peptide, an enzymolysis method and application in the field of bone repair product preparation. The invention provides an enzymolysis method of collagen peptide in cowhide, which comprises the following steps: degreasing fresh cowhide, removing impurities, fully crushing, firstly adding a deep eutectic solvent to assist extraction, then introducing a microbial fermentation enzyme to carry out enzymolysis, and carrying out ultrafiltration on an enzymolysis product to retain the part with the molecular weight of less than 3kDa, thereby obtaining the collagen peptide in the cowhide. Through verification, the collagen peptide prepared by the extraction process has good antioxidant activity and ACE inhibitory activity, has stem cell osteogenic differentiation induction activity, and is expected to be applied to bone repair activity research and product development.

This invention belongs to the field of composite material technology, and particularly relates to a porous gel material based on bovine collagen for the catalytic adsorption of low-concentration radionuclide resources in seawater, and its preparation method. The porous gel material comprises: bovine collagen powder, graphene oxide, montmorillonite, and a zirconium-based metal-organic framework; the porous gel material has a three-dimensional porous network structure with a pore size distribution of 80–800 nm and a specific surface area ≥300 m². 2 / g, porosity ≥75%. The preparation method includes preparing dispersions of montmorillonite, graphene oxide, bovine collagen solution, and zirconium-based metal-organic framework material; obtaining a composite precursor solution and an initial gel through crosslinking and dispersing agents; and then subjecting the initial gel to freeze-thaw cycles and vacuum freeze-drying. The target product of this invention possesses high adsorption capacity, excellent catalytic activity, good mechanical stability, and good dispersibility.

The invention belongs to the technical field of nutrients, and discloses an immune steady-state regulation type cartilage repair compound nutrient and a preparation process thereof. The nutrient comprises 150 parts of calcium L-aspartate, 100 parts of purified konjac powder, 80 parts of marine fish oligopeptide, 70 parts of roxburgh rose powder, 10 parts of taurine, 30 parts of angelica sinensis extract, 20 parts of turmeric extract, 20 parts of rhizoma polygonati extract, 15 parts of selenium-enriched barley malt powder, 10 parts of yeast B-glucan, 50 parts of bovine bone collagen peptide powder, 5 parts of sodium hyaluronate, 25 parts of 2-oxoglutaric acid and 30 parts of earthworm protein. The formula comprises the following components in parts by weight: 20 parts of colostrum basic protein powder, 40 parts of non-denatured II-type bone collagen, 0.01 part of vitamin D3, 50 parts of soluble soybean polysaccharide, 5 parts of citric acid, 0.5 part of nisin, 0.5 part of B-carotene and 1 part of sucralose. The product can scavenge free radicals, clean intestinal tracts, regulate immunity, regulate clogging and qi and blood, supplement calcium ions and high-quality multi-layer nutrient substances, and repair damaged cartilage tissues and skeletal systems.

The application discloses a bovine collagen active peptide as well as a preparation method and application thereof. The amino acid sequence of the bovine collagen active peptide is selected from SEQ ID NO. 1 to SEQ ID NO. 5, and the bovine collagen active peptide can be used for screening and / or preparation of biomedical materials or medicines for resisting inflammation, oxidation or atherosclerosis. The bovine collagen active peptide disclosed by the application is not only non-toxic and non-sensitizing, but also has good free radical scavenging capacity, Fe 2+ chelating capacity and total antioxidant capacity, and can inhibit inflammation of Raw264.7 macrophages induced by ox-LDL.

The invention provides a sustained-release protein gel and a preparation method thereof, and belongs to the field of biological medicine, and specifically, the preparation method of the sustained-release protein gel provided by the invention comprises the following steps: S1, adding protein into cross-linked sodium hyaluronate to form a primary mixture, the protein is selected from at least one of type I bovine collagen, human serum albumin and egg white lysozyme, and the cross-linked sodium hyaluronate is sodium hyaluronate cross-linked by a terminal epoxy group cross-linking agent; s2, performing high-pressure homogenization on the primary mixture in the step S1 to obtain gel particles with uniform particle size; and S3, carrying out static adsorption equilibrium on the gel particles in the step S2 to obtain the sustained-release protein gel. The sustained-release protein gel prepared by adopting the preparation method does not generate a Tyndall effect, and has the advantages of high strength and low adverse reaction occurrence rate.

The invention belongs to the technical field of skin repair, and particularly relates to a multifunctional yak collagen hydrotherapy needle and application thereof in skin photoaging. The invention provides a multifunctional yak collagen water-light injection. The water-light injection is prepared from the following components: yak collagen, vitamin C, alpha-arbutin, sodium hyaluronate, NMN, PDRN and copper blue peptide. The water-light needle has the remarkable effects of resisting oxidation, whitening, preserving moisture, promoting tissue repair and relieving; in addition, the yak collagen has excellent biological safety, no cytotoxicity, no whole-body toxicity, no pyrogenicity and no hemolysis risk, and the yak collagen keeps a complete triple-helix structure; the water-light needle can effectively improve skin texture, improve skin density and hydration, significantly reduce transdermal moisture loss, promote skin color to recover to a healthy state, significantly promote collagen regeneration and accelerate a photoaging skin recovery process, and has important significance in the field of skin photoaging repair.

The invention discloses a composition containing cerebroprotein hydrolysate as well as a preparation method and application thereof. The composition has the main effects of improving memory, tranquilizing and allaying excitement and assisting digestion. Experiments prove that the combination of the deer brain protein hydrolysate, the pig brain protein hydrolysate and the bovine collagen peptide powder can improve the learning and memory ability of transgenic mice with Alzheimer's disease, and the combination of the deer brain protein hydrolysate, the pig brain protein hydrolysate and the bovine collagen peptide powder can further repair damaged nerve cells. The sea-buckthorn can reduce damage caused by oxygen free radicals and accelerate removal of free radicals in the body. Hawthorn and endothelium corneum gigeriae galli can improve the digestive function of a user, so that nutritional ingredients in the composition are fully absorbed by a human body. And the anti-oxidation effect of the vitamin C and the vitamin B5, the nervous system health maintaining effect of the vitamin B1, the vitamin B6 and the vitamin B12 and the carbohydrate fat protein hydrolysis accelerating effect of the vitamin B3 are supplemented, so that the whole formula composition has a certain effect of preventing the Alzheimer's disease and has a good application prospect.

The application discloses a kind of bovine collagen peptide for increasing bone density and a preparation method thereof, and relates to the technical field of enzyme processing preparation of protein peptide.The application relates to the application of bovine collagen peptide in the field of composition.The composition containing bovine collagen peptide is prepared from the following components in mass fraction:bovine collagen peptide 25-45 parts, calcium citrate 12-28 parts, vitamin D 0.0002-0.0004 parts, extract of rhizoma drynariae 6-14 parts, extract of astragalus 4-9 parts, auxiliary materials 12-38 parts, and zoledronate derivative 0.01-0.05 parts.The application breaks through the limitation of single component and poor synergistic effect in the prior art, and forms a multi-dimensional action system of "inhibiting bone resorption, promoting bone formation and supplementing matrix" by matching bovine collagen peptide, calcium citrate, traditional Chinese medicine extract and modified zoledronate derivative, so that the effect of improving bone density is improved.