17 results about "Hydroxy derivative" patented technology

The invention belongs to the field of flame retardants, and particularly relates to a polyhydroxy DOPO derivative, a polyhydroxy DOPO derivative / organic montmorillonite composite material and a preparation method thereof. In order to further improve the flame retardance of an epoxy resin composite material and maintain better thermal performance of the composite material, DL-tyrosine, vanillin and DOPO are taken as reactants, P-H in a DOPO structure and C = N in a Schiff base intermediate generated by Schiff base reaction of the DL-tyrosine and the vanillin are subjected to addition reaction, and the hydroxyl-containing DOPO-based flame retardant is synthesized. The method is used for modifying the EP / OMMT nano composite material, and the EP / OMMT / DV-DOPO nano composite material with high flame retardance and enhanced carbon layer strength and mechanical properties is prepared.

Provided are a cyclophosphazene reactive flame retardant containing a benzocyclobutene group, and a preparation method therefor and the use thereof. In the molecular structural formula of the provided cyclophosphazene reactive flame retardant containing a benzocyclobutene group, at least one benzocyclobutene group is comprised on the phosphazene ring. The provided preparation method for the cyclophosphazene reactive flame retardant containing a benzocyclobutene group comprises: reacting a hydroxyl compound at least containing a hydroxyl BCB derivative with a halogenated cyclophosphazene under the action of an acid-binding agent, and purifying the product, so as to obtain a cyclophosphazene reactive flame retardant containing a benzocyclobutene group. Provided is a resin composition, to which the cyclophosphazene reactive flame retardant containing a benzocyclobutene group is applied; and in addition to the cyclophosphazene reactive flame retardant containing a benzocyclobutene group, the resin composition comprises at least one of an unsaturated monomer, an unsaturated resin, a benzocyclobutene monomer and a benzocyclobutene resin, which are polymerized under certain conditions so as to form a bulk flame retardant material. In the flame retardant material, nitrogen and phosphorus are synergistically flame retardant. The flame retardant material does not contain a polar group, has a low DK and Df, and has a high Tg, such that the flame retardant material is applied to a high-frequency and high-speed copper-clad laminate material.

According to the invention, a preparation is described which contains at least one calcium compound selected from the group consisting of calcium phosphates, calcium fluorides and calcium fluorophosphates and hydroxyl derivatives and carbonate derivatives of these calcium salts, calcium hydroxides and calcium oxides precipitated using at least one protein component selected from proteins and protein hydrolysates, and at least one crosslinking agent for the protein component and / or non-set cement.

Provided is an aqueous solution for producing an electronic device, which is capable of suppressing defects. Provided is an aqueous solution for producing an electronic device, which contains (A) a sulfonic acid derivative having a specific structure, (B) a water-containing solvent, and (C) a hydroxyl derivative having a specific structure.

This invention belongs to the field of pharmaceutical technology and discloses arbutin, its polyhydroxy derivatives, their compositions, and uses. Using a microbial transformation method, this invention successfully modified the structure of arbutin, obtaining three novel arbutin derivatives with polyhydroxy substitutions. In vitro neuronal inflammation assays and neuronal oxidative damage protection assays confirmed that these compounds possess good anti-neuroinflammatory and neuronal damage protective activities. Simultaneously, in vivo Alzheimer's disease mouse model experiments demonstrated that these compounds can significantly improve the learning and memory abilities of AD mice, and can serve as active ingredients in drugs for treating neurological diseases. In vitro antitumor cell assays confirmed that compounds I-III possess significant antitumor activity and can serve as active ingredients in antitumor drugs, with broad applications.

The present invention relates to a novel enzyme capable of producing multi-hydroxy derivatives from polyunsaturated fatty acids and a method for producing multi-hydroxy derivatives of polyunsaturated fatty acids using the same.

The invention provides high-refractive-index light-cured resin and a preparation method thereof. An intramolecular structure of the light-cured resin comprises a flexible block, a rigid block and an active block. The flexible block is realized by introducing a high-refractive-index dithioether derivative, the rigid block is realized by introducing an arylethene derivative, and the active block introduces a photocuring active group through a hydroxyl derivative. The light-cured resin provided by the invention is prepared through two-step reaction, the refractive index can reach 1.7 or above, and the light-cured resin has relatively high mechanical strength and good flexibility, and can be used for manufacturing products such as high-refractive-index optical cement, high-refractive-index nanoimprint adhesive, high-refractive-index adhesive, high-refractive-index lens, high-refractive-index ink and the like.

An electronic device manufacturing aqueous solution includes a sulfonic acid derivative (A) having a certain structure, an aqueous solvent (B), and a hydroxy derivative (C).

The invention discloses a design method and application of a total chemical synthesis ribonucleic acid (RNA) drug capable of translating protein, and belongs to the technical field of biological medicine. According to the method, RNA with the following characteristics is synthesized through a chemical synthesis instrument: the 5'terminal is hydroxyl or a hydroxyl derivative or a ribozyme sequence capable of generating 5 'hydroxyl through self-shearing; the 3'terminal is monophosphate or 2 '-3' cyclic phosphoric acid, or a ribozyme sequence capable of generating 3 'monophosphate or 2'-3 'cyclic phosphoric acid by self-shearing; the middle region contains a translation starting element and a target gene sequence. The RNA can be rapidly synthesized through a chemical synthesis instrument, can be applied to vaccine development, can be used for rapidly preparing individualized RNA cancer vaccines, and has the advantage of rapid response. The RNA has the advantage of low immunogenicity, and can induce an organism to establish epitope specific immune tolerance, so that the RNA can be used for treating autoimmune diseases; the polypeptide can also be used for expressing functional proteins or polypeptides and is used for protein / polypeptide replacement therapy.

The invention relates to the technical field of calcium carbonate powder modification, and discloses a modified multifunctional calcium carbonate and a preparation method thereof. The modified multifunctional calcium carbonate comprises the following components in proportion by weight: 100 parts of calcium carbonate, 0.3-0.5 parts of coupling agents, 0.4-0.7 parts of alpha-linolenic acid polyhydroxy derivatives, 0.5-1.0 parts of 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide derivatives, 0.05-0.15 parts of rosmarinic acid and derivatives thereof, 0.2-0.35 parts of chitosan / chitosan oligosaccharide derivatives, and 0.2-0.3 parts of titanium dioxide. The modified multifunctional calcium carbonate has multiple functions, a wide range of applications, and moderate costs. When used for filling different plastic materials, the modified multifunctional calcium carbonate has the advantages of improved physical and mechanical properties, reduced flame retardant costs, increased fluidity, and the like, and can also produce antibacterial, anti-aging, deodorizing, and the like functions. When used for adhesive filling, the modified multifunctional calcium carbonate has the advantages of high extrudability of the finished adhesive, high mechanical properties, low sag, and the like, and is a rare multifunctional filler.

The present invention relates to a novel enzyme capable of producing multi-hydroxy derivatives from polyunsaturated fatty acids and a method for producing multi-hydroxy derivatives of polyunsaturated fatty acids using the same.

The present application belongs to the field of new daily chemical materials and discloses a carrier based on an association network, wherein the carrier is a nano-scale or micron-scale particle in water; the carrier is a network carrier composed of arginine components and hyaluronic acid components associated by hydrogen bonds and / or ionic bonds; the carrier is based on the electrostatic binding force and hydrogen bonding force of hyaluronic acid and its derivatives, arginine and its polyhydroxy derivatives, to achieve effective binding for one or more small molecule polar active substances, and can promote the effective size reduction of hyaluronic acid and its salt derivatives in the carrier matrix material, thereby improving its own effective skin permeability; at the same time, further improving the physicochemical stability, transdermal transmissibility, sustained release and skin care effects of other active ingredients loaded by the carrier. At the same time, the present invention also provides a composition and the use and cosmetics of the carrier and the composition.

The invention relates to the field of flame retardants, in particular to a reactive flame retardant containing benzocyclobutene cyclophosphazene as well as a preparation method and application of the reactive flame retardant. The invention provides a reactive flame retardant containing benzocyclobutene group cyclophosphazene. In the molecular structural formula of the reactive flame retardant, a phosphazene ring at least comprises one benzocyclobutene group. The invention provides a preparation method of a reactive flame retardant containing benzocyclobutene group cyclophosphazene, which comprises the following steps: reacting a hydroxyl compound at least containing a hydroxyl BCB derivative with halogenated cyclophosphazene under the action of an acid-binding agent, and purifying to obtain the reactive flame retardant containing benzocyclobutene group cyclophosphazene. The resin composition applied to the reactive flame retardant containing the benzocyclobutene group cyclophosphazene, provided by the invention, comprises the reactive flame retardant containing the benzocyclobutene group cyclophosphazene, and further comprises at least one of an unsaturated monomer, unsaturated resin, a benzocyclobutene monomer and benzocyclobutene resin, the main flame-retardant material is formed through polymerization under a certain condition, nitrogen and phosphorus achieve synergistic flame retardance, and the flame-retardant material does not contain polar groups, has low DK, Df and high Tg and is applied to a high-frequency and high-speed copper-clad plate material.

The invention relates to the preparation of estetrol of formula (I), derivatives thereof protected at positions 3,15α, 16α, 17β of general formula (III), and 3-hydroxy derivatives thereof protected at positions 15α,16α,17β of general formula (IV), and to the intermediates of general formulas (III) and (IV) applicable to the process. Another aspect of the invention is the use of estetrol of formula (I) obtained by the process of the invention for the preparation of a pharmaceutical composition.

The present invention provides a UV-curable polyurethane with synergistic flame retardancy of bispirocyclic phosphate and silicone and a preparation method thereof. The preparation method comprises the following steps: adding a hydroxyl derivative of bispirocyclic pentaerythritol diphosphate and a hydroxyl-terminated polysiloxane together into a three-necked flask equipped with a mechanical stirrer and a thermometer, stirring evenly, dropping dibutyltin dilaurate and diisocyanate to react, and then adding hydroxypropyl methacrylate, continuing the reaction to obtain a polyurethane prepolymer containing bispirocyclic phosphate and silicone; then adding an ultraviolet light initiator, and UV curing to obtain the above-mentioned UV-curable polyurethane. The UV-curable material has a pencil hardness of 2B~9H, an initial thermal decomposition temperature of 246.0~298.2℃, an LOI of 26.0~33.2%, and a flame retardancy grade of V‑1~V‑0, and can be used as electronic flame retardant sealant, flame retardant three-proof paint, flame retardant industrial paint, flame retardant tent cloth coating, etc.

The present invention relates to the technical field of flame retardants, in particular a reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group, and a method for its preparation and application. The present invention provides a reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group, wherein the phosphazone ring in a molecular structural formula comprises at least one benzocyclobutene group. The present invention provides a method for the preparation of a reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group. This is achieved by reacting a hydroxy compound containing at least one hydroxy BCB derivative with a halogenated cyclophosphazone under the influence of a binding acid, followed by a purification treatment to obtain the reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group.The present invention provides a resin composition for the application of a reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group, wherein the resin composition comprises the reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group. It further comprises at least one of unsaturated monomers, unsaturated resins, benzocyclobutene monomers, or benzocyclobutene resins which are polymerized under certain conditions to form flame-retardant main body materials. These exhibit synergistic nitrogen-phosphorus flame retardancy, have no polar groups, and are characterized by low Dk and Df values ​​as well as a high Tg value, making them suitable for copper-clad high-frequency and high-speed materials.

A solvent blend including a substituted oxazolidinone and one or both of an alkylene glycol and an alkylene carbonate or hydroxy-derivative thereof. Said solvent blend for use in a variety of applications including semiconductor processing, secondary batteries, paint removers, petrochemical processing, agricultural chemical, and pharmaceuticals. A method including applying a slurry having a process solvent to a conductive substrate; and evaporating the process solvent. Another method including evaporating at least a portion of a process solvent in a slurry to produce a conductive electrode precursor; and applying the conductive electrode precursor to a conductive substrate. The slurry may include a conductive additive, an electrode active material, a binder, and a process solvent, where the process solvent comprises a substituted cyclic urethane. Such methods may be useful in producing a cathode or an anode for a secondary battery.