7 results about "Hydroxy derivative" patented technology

The invention belongs to the field of flame retardants, and particularly relates to a polyhydroxy DOPO derivative, a polyhydroxy DOPO derivative / organic montmorillonite composite material and a preparation method thereof. In order to further improve the flame retardance of an epoxy resin composite material and maintain better thermal performance of the composite material, DL-tyrosine, vanillin and DOPO are taken as reactants, P-H in a DOPO structure and C = N in a Schiff base intermediate generated by Schiff base reaction of the DL-tyrosine and the vanillin are subjected to addition reaction, and the hydroxyl-containing DOPO-based flame retardant is synthesized. The method is used for modifying the EP / OMMT nano composite material, and the EP / OMMT / DV-DOPO nano composite material with high flame retardance and enhanced carbon layer strength and mechanical properties is prepared.

Provided are a cyclophosphazene reactive flame retardant containing a benzocyclobutene group, and a preparation method therefor and the use thereof. In the molecular structural formula of the provided cyclophosphazene reactive flame retardant containing a benzocyclobutene group, at least one benzocyclobutene group is comprised on the phosphazene ring. The provided preparation method for the cyclophosphazene reactive flame retardant containing a benzocyclobutene group comprises: reacting a hydroxyl compound at least containing a hydroxyl BCB derivative with a halogenated cyclophosphazene under the action of an acid-binding agent, and purifying the product, so as to obtain a cyclophosphazene reactive flame retardant containing a benzocyclobutene group. Provided is a resin composition, to which the cyclophosphazene reactive flame retardant containing a benzocyclobutene group is applied; and in addition to the cyclophosphazene reactive flame retardant containing a benzocyclobutene group, the resin composition comprises at least one of an unsaturated monomer, an unsaturated resin, a benzocyclobutene monomer and a benzocyclobutene resin, which are polymerized under certain conditions so as to form a bulk flame retardant material. In the flame retardant material, nitrogen and phosphorus are synergistically flame retardant. The flame retardant material does not contain a polar group, has a low DK and Df, and has a high Tg, such that the flame retardant material is applied to a high-frequency and high-speed copper-clad laminate material.

According to the invention, a preparation is described which contains at least one calcium compound selected from the group consisting of calcium phosphates, calcium fluorides and calcium fluorophosphates and hydroxyl derivatives and carbonate derivatives of these calcium salts, calcium hydroxides and calcium oxides precipitated using at least one protein component selected from proteins and protein hydrolysates, and at least one crosslinking agent for the protein component and / or non-set cement.

This invention belongs to the field of pharmaceutical technology and discloses arbutin, its polyhydroxy derivatives, their compositions, and uses. Using a microbial transformation method, this invention successfully modified the structure of arbutin, obtaining three novel arbutin derivatives with polyhydroxy substitutions. In vitro neuronal inflammation assays and neuronal oxidative damage protection assays confirmed that these compounds possess good anti-neuroinflammatory and neuronal damage protective activities. Simultaneously, in vivo Alzheimer's disease mouse model experiments demonstrated that these compounds can significantly improve the learning and memory abilities of AD mice, and can serve as active ingredients in drugs for treating neurological diseases. In vitro antitumor cell assays confirmed that compounds I-III possess significant antitumor activity and can serve as active ingredients in antitumor drugs, with broad applications.

The invention relates to the field of flame retardants, in particular to a reactive flame retardant containing benzocyclobutene cyclophosphazene as well as a preparation method and application of the reactive flame retardant. The invention provides a reactive flame retardant containing benzocyclobutene group cyclophosphazene. In the molecular structural formula of the reactive flame retardant, a phosphazene ring at least comprises one benzocyclobutene group. The invention provides a preparation method of a reactive flame retardant containing benzocyclobutene group cyclophosphazene, which comprises the following steps: reacting a hydroxyl compound at least containing a hydroxyl BCB derivative with halogenated cyclophosphazene under the action of an acid-binding agent, and purifying to obtain the reactive flame retardant containing benzocyclobutene group cyclophosphazene. The resin composition applied to the reactive flame retardant containing the benzocyclobutene group cyclophosphazene, provided by the invention, comprises the reactive flame retardant containing the benzocyclobutene group cyclophosphazene, and further comprises at least one of an unsaturated monomer, unsaturated resin, a benzocyclobutene monomer and benzocyclobutene resin, the main flame-retardant material is formed through polymerization under a certain condition, nitrogen and phosphorus achieve synergistic flame retardance, and the flame-retardant material does not contain polar groups, has low DK, Df and high Tg and is applied to a high-frequency and high-speed copper-clad plate material.

The invention relates to the preparation of estetrol of formula (I), derivatives thereof protected at positions 3,15α, 16α, 17β of general formula (III), and 3-hydroxy derivatives thereof protected at positions 15α,16α,17β of general formula (IV), and to the intermediates of general formulas (III) and (IV) applicable to the process. Another aspect of the invention is the use of estetrol of formula (I) obtained by the process of the invention for the preparation of a pharmaceutical composition.

The present invention relates to the technical field of flame retardants, in particular a reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group, and a method for its preparation and application. The present invention provides a reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group, wherein the phosphazone ring in a molecular structural formula comprises at least one benzocyclobutene group. The present invention provides a method for the preparation of a reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group. This is achieved by reacting a hydroxy compound containing at least one hydroxy BCB derivative with a halogenated cyclophosphazone under the influence of a binding acid, followed by a purification treatment to obtain the reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group.The present invention provides a resin composition for the application of a reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group, wherein the resin composition comprises the reactive flame retardant comprising a cyclophosphonitrile benzocyclobutene group. It further comprises at least one of unsaturated monomers, unsaturated resins, benzocyclobutene monomers, or benzocyclobutene resins which are polymerized under certain conditions to form flame-retardant main body materials. These exhibit synergistic nitrogen-phosphorus flame retardancy, have no polar groups, and are characterized by low Dk and Df values ​​as well as a high Tg value, making them suitable for copper-clad high-frequency and high-speed materials.