114 results about "Skin impedance" patented technology

The invention provides a multi-source biological signal fusion moxibustion electric control method and system. In the moxibustion applying process, a multi-source biological signal flow is formed by obtaining an epidermal impedance dynamic waveform and a heart rate variability signal, a skin impedance baseline map of a physiological feature parameter library and a heart rate variability association rule are dynamically matched, and an acupoint sensitivity index and a heat tolerance threshold value are generated; triggering an infrared thermal imaging device to scan a moxibustion application area based on the sensitivity index, reconstructing a heat conduction model in combination with the epidermal layer thickness and the acupoint distribution density, comparing an epidermal impedance dynamic waveform with a skin impedance baseline map through a phase offset, and calculating a targeted thermal field compensation gradient of the acupoint area; and finally, coupling the thermal tolerance threshold and the space-time parameters of the target thermal field compensation gradient to generate a control instruction set. According to the technical scheme, accurate regulation and control of thermal field distribution and optimization of the motion path of the mechanical arm in the moxibustion applying process are achieved.

The invention relates to the field of medical instruments, and discloses an anesthesia injury monitoring evaluation and management system for pain monitoring and rehabilitation acceleration. Comprising a sensor module configured to collect acupuncture point skin temperature data in a percutaneous acupuncture point electrical stimulation process, current parameter data output by an electrical stimulation device and skin impedance change data in real time; the control module is used for inputting the temperature data, the current parameter data and the skin impedance data which are acquired in real time into a multi-parameter risk assessment model, calculating a real-time risk value and generating a parameter change curve containing a time sequence; when the real-time risk value exceeds a preset safety threshold value, or any single parameter in the parameter change curve reaches a temperature change rate threshold value, an accumulated electrical stimulation energy threshold value or a skin impedance abnormal fluctuation threshold value, triggering a multi-stage early warning signal; according to the early warning level of the early warning module, the output power, the pulse frequency or the action time of the electrical stimulation device is automatically adjusted, or electrical stimulation is forcibly terminated when early warning is performed at the highest level.

The invention relates to the technical field of electric acupuncture apparatuses, and discloses a method and a system for automatically adjusting stimulation parameters of an electric acupuncture apparatus. According to the method, body surface electromyographic signals, skin impedance and capillary hemodynamic parameters of a user are collected in real time through a sensor set, feature extraction and analysis are conducted through a time sequence prediction model of a Transform architecture, and physiological feature data are generated. And then, constructing a user physiological state characterization model by adopting a multi-modal neural perception fusion algorithm, and carrying out collaborative optimization on the electrical stimulation parameters through an adaptive quantum particle swarm optimization algorithm to generate a stimulation parameter combination matched with the real-time neuromuscular response characteristics of the user. The system drives electrical stimulation output according to the parameter combination, monitors physiological data changes in real time, realizes closed-loop dynamic balance of stimulation parameters and biological feedback signals through the dynamic parameter compensation module, and improves the treatment effect and safety.

A system of fibers, filaments, and / or other electrically conductive materials forms an electrically conductive-to-semi-conductive yarn that can be assembled into a textile for measurement of voltage, current, resistance, capacitance, inductance, RF, and / or EM signals. Textiles are formed through weaving, knitting, lacing, and / or non-woven mechanical methods of yarn-making into 2D / 3D structures. Textile-based electrodes can be formed via folding, cutting, layering, sewing, and / or embroidering patterns to control signal transmission within / through the electrode. Multiple electrodes are positioned on a surface (e.g., a body) to sequentially or simultaneously perform multiple diagnostic modalities (e.g., electrocardiography, electromyography, electrooculography, electroencephalogram, bioelectrical impedance analysis, skin impedance analysis, and / or electrodermal activity). These modalities are multiplexed using an optimized electrode set through amplitude and frequency deconvolution and filtering algorithms to minimize the quantity of electrodes and connections on the surface while maximizing signal-to-noise ratio, differential and common mode noise rejection, and elimination of external signals (e.g., RF and EM noise).

The invention relates to the field of nano-drug delivery preparations, in particular to a traditional Chinese medicine transdermal drug delivery preparation based on a nano-coating technology and a preparation method thereof, the traditional Chinese medicine transdermal drug delivery preparation comprises a liposome-metal organic framework composite carrier, and the composite carrier comprises traditional Chinese medicine active ingredients; a meridian point targeted transdermal enhancer; an iontophoresis device for dynamically sensing skin impedance; the invention relates to an intelligent administration time sequence control system based on a traditional Chinese medicine midnight-noon ebb-flow theory. The liposome-metal organic framework composite carrier is adopted, the similar structure of liposome and skin and the high specific surface area of MOF are fully utilized, efficient encapsulation and transdermal absorption of active ingredients of traditional Chinese medicine are achieved, and compared with a traditional transdermal patch, the drug transdermal absorption rate is increased by 3-5 times.

The invention provides an acupoint positioning and electric pulse regulation and control device and method based on electrical impedance feedback, and the device comprises a bioelectrical impedance detection module which is provided with a flexible wearing hardware part, and the flexible wearing hardware part is provided with an electrode for collecting a skin electrical impedance signal, the bioelectrical impedance detection module determines a target acupuncture point area for placing an electrode according to the electrical impedance signal; the initial pulse output module is used for outputting a preset initial electric pulse signal to an electrode of the flexible wearing hardware part; the dynamic cooperative control module is used for adjusting an electric pulse parameter according to a real-time skin electrical impedance signal acquired by the electrode after the initial electric pulse signal is applied to the target acupuncture point area through the electrode; the electric pulse output module outputs electric pulse signals to an electrode according to the adjusted electric pulse parameters, acupuncture points can be accurately positioned, the electric pulse output parameters can be accurately adjusted, stimulation output is dynamically optimized through a feedback mechanism under the condition that the skin state of a patient changes or the characteristics of the acupuncture points are different, and the treatment effect and the comfort of the patient are improved.

The invention discloses an adjustable blood transfusion reaction monitoring system. The system comprises a multi-mode physiological signal acquisition module, a data processing and analysis module, a user interaction and parameter configuration interface, a wireless communication module, an alarm and feedback module and a power management module. By integrating an electrocardiogram (ECG) sensor, an oxyhemoglobin saturation (SpO2) detection probe, a non-invasive blood pressure measuring device, a body temperature sensor, a respiratory rate monitor and a skin impedance change sensor, real-time acquisition of various physical parameters is realized; a rule-based threshold judgment model and a time sequence prediction model are built in the data processing and analysis module, and the data processing and analysis module is used for identifying potential blood transfusion reaction risks; and the user interaction and parameter configuration interface provides a touch display screen and remote terminal equipment to realize information input, data display and operation recording. Continuous dynamic monitoring, intelligent early warning and graded response in the blood transfusion process are achieved, blood transfusion safety and nursing efficiency are improved, and the system has wide clinical application prospects.

The invention provides a neutral electrode heat effect test method and system, and relates to the field of neutral electrode detection. The invention relates to a neutral electrode heat effect test method, which comprises the following steps of: attaching a neutral electrode to a contact unit of one or more of a plurality of test modules; the contact units are conducted with the corresponding direct connection units; determining at least part of the plurality of test modules as initial effective test modules; acquiring an attachment safety threshold value of the neutral electrode, and selecting at least part of the initial effective test modules as final effective test modules according to the attachment safety threshold value; the contact unit of the final effective test module is conducted with the corresponding human body skin impedance unit; and after the first current is continuously applied to the neutral electrode within the first time period, temperature rise temperature data of each final effective test module is obtained, and the heat effect data comprises the temperature rise temperature data.

The invention discloses a sleep-aiding linkage system based on ankle recovery monitoring, and relates to the technical field of medical health and intelligent monitoring. According to the sleep-aiding linkage system based on ankle recovery monitoring, rich biomechanical parameters of an ankle area are collected in real time through a multi-mode sensor; the method comprises the steps that plantar pressure distribution, ankle joint motion trails, foot temperature and skin impedance are covered, the data are subjected to multi-dimensional fusion analysis, calculation is conducted in combination with a built-in neural network model, the ankle fatigue state and the recovery stage can be accurately analyzed, the method is different from a traditional fixed threshold value judgment mode, and the system can be dynamically adjusted according to individual differences of users and historical data; and furthermore, the sleep-aiding equipment linkage control module is used for finely adjusting operation parameters of mattress hardness, environment illumination intensity and sound wave frequency for sleep monitoring equipment and environment temperature control equipment according to an analysis result, so that an exclusive sleep environment matched with an ankle recovery process is created for a user.

The invention relates to a multichannel neuromuscular electrical stimulation device and a control method thereof. The device comprises a multi-stage power supply generator which is provided with a booster circuit for generating N-stage voltage; a plurality of electrical stimulation channels; the digital control circuit comprises a controller and a plurality of channel control registers respectively corresponding to the plurality of electrical stimulation channels; the skin impedance detection circuit is configured to detect the skin impedance value of the stimulation part corresponding to the output electrode of each electrical stimulation channel; the multi-stage power generator further comprises a voltage selection unit for switchably connecting each electrical stimulation channel to the N voltage outputs, and the voltage selection unit is configured to select and / or switch a supply voltage for each electrical stimulation channel from the N voltage outputs according to a skin impedance value detected by the skin impedance detection circuit. According to the multi-channel neuromuscular electrical stimulation device and the control method thereof, flexible cooperative control among multiple channels and self-adaptive adjustment based on impedance are realized, and the system energy efficiency and the treatment accuracy are improved.

The invention discloses a cognitive state monitoring and intervention device and method. The cognitive state monitoring and intervention device comprises a microelectrode drug delivery array module, a wireless transceiving and control circuit module and a power supply module, a microcontroller is embedded in the wireless transceiving and control circuit module; the microelectrode drug delivery array module comprises a hollow drug delivery microneedle, a sensing electrode and a controlled drug delivery electrode; the hollow drug delivery microneedle comprises a hollow microneedle array and a drug storage chamber; the sensing electrode is coupled and fixed on a substrate of the hollow microneedle array, and is attached to the body surface to monitor skin impedance signals when in use, liquid medicine is stored in the medicine storage chamber, and a controlled administration electrode is mounted in the medicine storage chamber; when the wireless transceiving and control circuit module applies current to the controlled dosing electrode, the controlled dosing electrode and the liquid medicine generate electrochemical reaction, and the liquid medicine is pumped into the body surface through the microneedle. According to the invention, the cognitive function state of the body can be continuously monitored, and accurate administration can be automatically realized.

The invention relates to the field of intelligent medical treatment, in particular to a percutaneous lung channel acupoint electrical stimulation optimization system based on artificial intelligence, which comprises a multi-source data acquisition module (M1), a dynamic modeling module (M2) and a self-adaptive electrical stimulation module (M3). M1, collecting lung channel acupoint skin impedance, infrared thermal imaging, respiratory rhythm and cough frequency data in real time, and generating multi-source fusion features through space-time alignment; m2, based on a deep learning model, combining with a preset database to dynamically generate an electrical stimulation parameter combination, and ensuring parameter safety through impedance calibration and constraint optimization; and M3, adjusting the stimulation intensity according to the parameters, and setting an impedance threshold to trigger power-off protection. The traditional Chinese medicine meridian theory and the AI algorithm are fused, accurate acupoint positioning, personalized electrical stimulation and dynamic safety regulation are achieved, and the respiratory system disease treatment effect is improved.

The invention relates to the technical field of physiotherapy, in particular to a multi-mode physiotherapy system integrating ion release and electromagnetic stimulation. The system comprises a biological feedback sensing module, an intelligent control module, a space-time cooperative control module, a multi-channel ion release module, a multi-band electromagnetic generation module and a self-adaptive optimization module. Firstly, skin impedance, blood flow and temperature parameters are collected by the system, and a collaborative strategy is generated through multi-parameter analysis of an intelligent control module; the time-space cooperative control module synchronously adjusts the ion release and electromagnetic field excitation time sequence; the multi-channel ion release module realizes quantitative release of multiple types of ions by utilizing microfluidics; the multi-band electromagnetic generation module outputs low-frequency, medium-frequency and high-frequency programmable electromagnetic fields; the adaptive optimization module dynamically corrects treatment parameters based on the electrophysiological feedback. According to the system, multi-modal fusion of iontophoresis and electromagnetic stimulation is realized, and the accuracy and individualization level of treatment are improved.

The invention discloses a biological gel electrode based on polyvinyl alcohol and gelatin double-network crosslinking as well as a preparation method and application of the biological gel electrode, and belongs to the technical field of conductive hydrogel. According to the method, polyvinyl alcohol, gelatin, liquid metal, poly (3, 4-ethylenedioxythiophene)-polystyrolsulfon acid (PEDOT: PSS) and the like are used as main raw materials. Wherein the liquid metal gallium indium alloy is a conductive filler, sodium tetraborate is used as a cross-linking agent, and the biological double-network structure gel electrode with excellent conductivity, relatively low skin impedance and relatively good self-healing is obtained. As a biological electrode patch, the hydrogel prepared by the invention can be used for long-time and high-fidelity electrophysiological electrical signal acquisition, such as electrocardiosignals, electromyographic signals, electroencephalogram signals and the like. In addition, the biogel electrode provided by the invention is simple in preparation process, low in cost and good in biocompatibility, and has huge potential in the aspects of large-scale production, popularization and application of electrode patches.

The utility model discloses an ultrasonic beauty instrument based on multi-feedback automatic adjustment. The ultrasonic beauty instrument comprises a transducer, a drive circuit, a single chip microcomputer, an alternating current impedance detection unit, a temperature detection unit and a voltage and current detection unit. The skin impedance is detected through the alternating current impedance detection unit, the output of the driving circuit is adjusted, and then the ultrasonic intensity of the transducer is adjusted; the skin surface temperature is detected through the temperature detection unit, when it is detected that the skin temperature reaches a threshold value, output of ultrasonic waves is stopped, and a user is protected from being scalded; an output ultrasonic signal is monitored in real time through the voltage and current detection unit to adjust the frequency of an ultrasonic excitation signal output by the driving circuit, so that the transducer works on a resonance point all the time, automatic frequency tracking is achieved, and the accuracy of the output ultrasonic power is improved. Therefore, frequency tracking is carried out through multiple feedback modes of voltage and current detection, temperature detection and alternating current impedance detection, and the ultrasonic output intensity is automatically adjusted, so that a better use effect is achieved, and the use experience of a user is improved.

The invention discloses an electrical stimulation control method and device based on impedance feedback and a medium, and relates to the technical field of electrical stimulation. According to the scheme, a target electrical stimulation output mode set by a user is collected through a man-machine interaction module, and an initial impedance value of a detected target is detected through an impedance and voltage detection module; the main control module generates an initial output parameter according to the target electrical stimulation output mode and the initial impedance value, and the electrical stimulation module executes electrical stimulation output; the dynamic impedance value of the measured target is continuously monitored in the output process, and when the impedance of the measured target changes, the initial output parameter is adjusted so as to correct the electrical stimulation output. That is, according to the scheme, the impedance change of the measured target is continuously monitored in the electrical stimulation output process, and when the difference between the dynamic impedance value and the initial impedance value is found, the initial output parameter is adjusted to correct the electrical stimulation output so as to adapt to the dynamic change of the human skin impedance and maintain the stability of the current; and the safety and the reliability of electrical stimulation output are ensured.

A flexible ultrasonic transducer capable of detecting skin impedance, driving device and control method, the ultrasonic transducer includes coupling, electrode, array element and backing layers, and coupling layer includes a non-conductive and conductive flexible material; electrode layer is located below coupling layer, and second metal layer for connecting conductive flexible material and driving device, and fourth metal layer for connecting ground are arranged in electrode layer; array element layer is fit together with electrode layer and includes N transducer array elements, array element drive wires and flexible material, and flexible material fills among transducer array elements; backing layer is located below array element layer. The flexible transducer in conjunction with the driving device and control method can realize detection of skin impedance. Based on skin impedance, fit degree of transducer can be detected, and real-time evaluation and feedback control of ultrasonic emission effect can be realized in emission process.

The invention provides a flexible wearable ultrasonic probe based on a low-acoustic-impedance backing layer and a gradient matching layer and a preparation method of the flexible wearable ultrasonic probe. The flexible wearable ultrasonic probe comprises a probe body and an elastic body for packaging the probe body, wherein the probe body sequentially comprises a low-acoustic-impedance backing layer, a top electrode, a piezoelectric plate, a bottom electrode and a gradient matching layer from one side to the other side; the low-acoustic-impedance backing layer is a porous polymer, aerogel, cloth or air; the gradient matching layer comprises a plurality of matching layers which are arranged in a stacked mode, and the acoustic impedance of the matching layers is sequentially reduced in the direction from the position close to the bottom electrode to the position away from the bottom electrode; and the elastomer is a coupling material matched with the skin impedance. The flexible wearable ultrasonic probe has the advantages of high bandwidth, low insertion loss and excellent mechanical tensile property, and can be widely adapted to ultrasonic application scenes of various different principles such as A-type ultrasonic, B-type ultrasonic and Doppler ultrasonic.

The skin treatment device of the present invention comprises: a radio frequency (RF) generator for generating RF energy; an electrode for transmitting the RF energy to a skin tissue of a user; a measurement unit for measuring a forward RF voltage caused by the RF energy and a reverse RF voltage caused by the RF energy reflected to the RF generator; and a controller for calculating a skin impedance and an RF energy efficiency of the user based on the measured forward RF voltage and the reverse RF voltage, and controlling an output of the RF generator based on the calculated skin impedance and the RF energy efficiency.

The invention relates to a multi-modal information feedback regulation and control electrical stimulation method and system, and the system comprises an electrical stimulation device, a multi-modal information feedback regulation and control upper computer, and a data collection device. According to the method, inertia information, hand distributed pressure data and skin impedance data in the muscle action process are fully considered, and features are extracted from the data to determine initial stimulation parameters such as channels, frequencies, pulse widths and amplitudes. In addition, when stimulation is carried out according to the initial electrical stimulation parameters, distributed pressure data and multi-channel inertial data of the hand are collected in real time, then an actual muscle activation graph is obtained in combination with a machine learning model, and the actual muscle activation graph is fused with the ideal muscle activation graph and first spatial data extracted from skin impedance data respectively, so that the actual muscle activation graph is obtained. And the electrical stimulation parameters are dynamically adjusted. And multi-modal information feedback regulation and control electrical stimulation is realized.

The present invention provides a skin impedance acquisition device, method and a negative pressure monitoring system in a cupping device. The skin impedance acquisition device includes: an impedance acquisition sheet and an acquisition component; the impedance acquisition sheet includes a substrate and at least two conductive electrodes, the conductive electrodes are arranged on the front of the substrate, and the at least two conductive electrodes are parallel to each other and extend from the first end of the substrate to the second end of the substrate; the back of the substrate is adhered to the inner wall of the cupping device through a back adhesive, the first end of the substrate is flush with the cupping mouth of the cupping device, and the second end of the substrate is connected to the acquisition component to fix the acquisition component in the cupping device and connect the conductive electrode to the impedance detection circuit; when the cupping device is adsorbed on the user's skin, the user's skin contacts the at least two conductive electrodes, and the acquisition component detects the user's skin impedance value and sends the skin impedance value to the monitoring host in a wireless communication mode. This solution can determine whether the negative pressure in the cupping device is safe and effective according to the impedance of the skin in the cupping device.

The invention discloses a skin impedance self-adaptive intermediate frequency physiotherapy instrument control system and a skin impedance self-adaptive intermediate frequency physiotherapy instrument control method.The control system comprises an electrode output unit, a main control unit, a current and voltage real-time sampling unit and an impedance value calculation unit, and the current and voltage real-time sampling unit is used for sampling real-time current and voltage when the electrode output unit works; the collected real-time current and voltage are sent to an impedance value calculation unit; the impedance value calculation unit is used for receiving the current and the voltage sent by the electrode output unit and calculating an impedance value generated by the skin of the user to the current pulse signal according to the current and the voltage values; the main control unit is used for receiving the impedance values calculated by the impedance value calculation unit, taking the impedance value received for the first time as a standard value, taking each impedance value received after the first time as a current real-time impedance value, comparing the standard value with the current real-time impedance value, and finally, according to a comparison result, determining the impedance value of the current real-time impedance value. And an instruction for increasing, maintaining or reducing the voltage output related parameters is sent to the electrode output unit.

The present application discloses a skin impedance acquisition method, storage medium and electronic device for a beauty instrument, which acquires the real-time movement acceleration of the beauty instrument according to a preset acquisition time interval, determines the movement distance data of the beauty instrument on the skin plane coordinate system within the preset acquisition time, and acquires the skin impedance data when the movement distance data meets the preset distance condition. The present application determines the movement distance data of the beauty instrument on the skin plane by acquiring the real-time movement acceleration of the beauty instrument, and acquires the current skin impedance data when the movement distance data meets the preset distance condition, ensuring that the impedance data at different positions on the skin can be acquired, improving the accuracy of the impedance data, and also constructing a skin impedance map through the impedance data at different positions, thereby providing more accurate reference data for the radio frequency output of the beauty instrument.

The invention provides a micro-current control method, a corneal iontophoresis system, electronic equipment and a medium, the micro-current control method is applied to a riboflavin iontophoresis device in corneal crosslinking, and the riboflavin iontophoresis device comprises a micro-current controller; the micro-current controller is electrically connected with the direct-current power supply and is used for converting constant current provided by the direct-current power supply into micro-current; the micro-current control method comprises the following steps: monitoring the current change of the output end of a micro-current controller in real time; monitoring the skin impedance change of the patient when the micro-current flows through the treatment area in real time; based on the current change and / or the skin impedance change, performing standard evaluation on the magnitude of the micro-current acting on the treatment area; and dynamically adjusting the micro-current which does not meet the standard so as to realize standard output of the micro-current. According to the application, by dynamically adjusting the magnitude of the micro-current, stable control of the current in the process of introducing riboflavin ions into the cornea is realized, and the safety and effectiveness of epithelial administration of riboflavin are improved.

The application discloses a starfish-imitated tube foot array hydrogel electrode and a preparation method thereof. The bottom of the conductive hydrogel electrode is provided with a starfish-imitated tube foot array. A single starfish-imitated tube foot comprises a stem and a terminal biomimetic sucker. The outer side of the sucker is a circular table structure, and the inner side is a cavity composed of a hemisphere. The integrated tube foot microstructure of the electrode is obtained by laser cutting of the hydrogel. First, the inner cavity structure is cut. Then, the outer side of the biomimetic tube foot shape is cut. Finally, the single biomimetic tube foot is inserted into the block-shaped hydrogel to form an array. The preparation method of the conductive hydrogel electrode comprises the following steps: first, a prepolymer is synthesized; then, the prepolymer, cationic monomers and anionic monomers are polymerized to obtain a hydrogel with anti-swelling and stable and excellent conductive performance. The conductive hydrogel electrode has the self-adhesion and anti-swelling ability when working underwater, can be closely combined with human skin, reduces the electrode-skin impedance, and improves the quality of underwater electromyographic signal collection.

This invention discloses a control method and control system for pulses in a physiotherapy device. The method includes: acquiring detection data collected by the patch during its operation; wherein the detection data includes: electromyography (EMG) data, skin impedance, skin temperature, and pressure distribution; identifying the patch's fit degree based on the skin impedance and pressure distribution; after the fit degree meets the standard, determining the current operating state category of the physiotherapy device based on the EMG data and skin temperature; obtaining electrode current compensation and heating power compensation for the patch based on the operating state category; and controlling the patch to adjust the current pulse and temperature based on the electrode current compensation and heating power compensation. This invention solves the technical problem in the prior art where physiotherapy devices cannot adaptively adjust different pulse controls for output, and can automatically adjust the current pulse and temperature parameters to suit the user when using the physiotherapy device, improving the user experience and ease of use.

The present disclosure provides a temperature detection method, system, and radio frequency beauty device based on skin impedance. The electrode head of the radio frequency beauty device includes multiple electrodes arranged in an array, and the multiple electrodes include at least two groups of electrode pairs. The method includes: determining N sub-regions of the dot matrix formed by the multiple electrodes, wherein the N sub-regions include a first sub-region; obtaining the skin impedance value detected in each sub-region; determining difference information, wherein the difference information includes the difference between the skin impedance value detected in the first sub-region and the skin impedance value detected in each sub-region; determining a target sub-region within the N sub-regions based on the temperature value of the first sub-region and the difference information; the temperature value of the target sub-region is greater than or equal to a first threshold value, and the first threshold value is greater than or equal to the temperature value of the first sub-region. The temperature detection method provided by the present application can improve the flexibility of temperature detection in the beauty device.

The present invention provides a skin impedance measurement method, system and bone conduction headset, including the following steps: Step S1. Generate an excitation signal U1 for exciting an external complex impedance, and transmit the excitation signal U1 to an electrode sheet in contact with the user's skin; Step S2. Collect the response signal U2 returned by the electrode sheet, perform gain amplification on the response signal U2 and then perform discrete Fourier transform processing to obtain the skin impedance Z of the response signal U2; Step S3. Calibrate the skin impedance Z with a gain coefficient G, where the gain coefficient G is obtained by looking up a mapping table, and this mapping is the correspondence between the measurement frequency corresponding to the collected response signal U2 and the set frequency, so as to obtain the calibrated skin impedance Z of the user. The present invention can quickly and accurately measure the skin permeability of the current user.

The invention relates to a control method and device of electrical stimulation equipment, computer equipment, a computer readable storage medium and a computer program product. The method comprises the steps of determining a target electrical stimulation mode in response to selection of an object on an electrical stimulation mode on target electrical stimulation equipment, and determining a correction relation corresponding to the target electrical stimulation mode; the target electrical stimulation equipment comprises electrodes arranged in pairs; performing electrical stimulation output based on the target electrical stimulation mode, and obtaining real-time skin impedance between the electrodes and a skin impedance change rate; when the skin impedance change rate exceeds a preset change rate, determining an expected current and an expected period according to the real-time skin impedance and a correction relation; and outputting current matched with the expected current according to the expected period, so that the electrode outputs corresponding electrical stimulation. By adopting the method, the use comfort of the electrical stimulation equipment can be improved.

The invention relates to the technical field of microneedle transdermal drug delivery, in particular to a puncture depth self-adaptive microneedle system. The microneedle system comprises a microneedle array used for puncturing skin, providing a sampling point for detecting skin impedance at a skin layer touched by a needle tip of the microneedle array, and releasing drugs; the detection unit is connected with the microneedle array and is configured to acquire skin impedance at the sampling point in a short pulse mode and output a control signal when it is judged that the needle tip of the microneedle array penetrates through the cuticle according to the skin impedance; the execution unit is respectively connected with the microneedle array and the detection unit and is configured to receive a control signal from the detection unit to stop the microneedle array from continuously puncturing into the skin after the detection unit judges the penetration, so that the penetration depth of the microneedle can be actively limited based on the electrical characteristic change of the skin in the penetration process of the microneedle; the problem of skin individual difference is effectively solved, and the active recognition capability and the automatic adjustment capability of the real-time penetration state are achieved.