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External medicinal composition for treating dermatosis and preparation method for external medicinal composition

A technology of external medicine and composition, applied in the field of medicine, can solve problems such as complex etiology, damage to body organs, poor treatment effect, etc., and achieve obvious therapeutic effect

Active Publication Date: 2014-01-22
陈嘉陵
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many types of skin diseases, the etiology is complex, and it is difficult to cure, which brings different degrees of distress to patients
Now on the market, there are many medicines for treating skin diseases, but most external medicines can only treat a specific skin disease, and the therapeutic effect is relatively poor for skin diseases caused by other etiology or multiple causes of disease; and Treating skin diseases by internal medicine will cause damage to body organs due to long-term medication

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] An external pharmaceutical composition for treating skin diseases, consisting of the following components by weight percentage: 5% metronidazole powder, 3% sulfur powder, 2% camphor, 25% clotrimazole cream, 35% micon Clotrimazole emulsifiable cream and 30% medical glycerin, wherein: metronidazole powder and sulfur powder pass through 80 mesh sieves, and the specification of clotrimazole emulsifiable paste is to contain 0.1g clotrimazole in every 10g clotrimazole emulsifiable paste, Manufacturer: Sinopharm Group Sanyi Pharmaceutical (Wuhu) Co., Ltd.; the specification of miconazole clobetasol cream is that every 10g of miconazole clobetasol cream contains 0.2g miconazole nitrate and 5mg chlorine propionate Betasol, manufacturer: Guangdong Taicheng Pharmaceutical Co., Ltd.

[0031] According to the above preparation process, add the metronidazole powder, sulfur powder and camphor in the above components into medical glycerin, heat to 80-100°C to fully mix the components, ...

Embodiment 2

[0036] An external pharmaceutical composition for treating skin diseases, consisting of the following components by weight percentage: 8% metronidazole powder, 2% sulfur powder, 2% camphor, 30% clotrimazole cream, 30% micon Clotrimazole emulsifiable cream and 28% medical glycerin, wherein, metronidazole powder and sulfur powder pass through 70 mesh sieves, and the specification of clotrimazole emulsifiable paste is to contain 0.1g clotrimazole in every 10g clotrimazole emulsifiable paste, Manufacturer: Harbin Pharmaceutical Group Sanjingmei Pharmaceutical Co., Ltd.; the specification of miconazole clobetasol cream is that every 10g of miconazole clobetasol cream contains 0.2g miconazole nitrate and 5mg clobetasol propionate cable, manufacturer: Zhejiang Shengji Pharmaceutical Co., Ltd. According to the preparation process of the aforementioned Example 1, the external pharmaceutical composition of the present invention was obtained.

[0037] For the external pharmaceutical com...

Embodiment 3

[0040]An external pharmaceutical composition for treating skin diseases, consisting of the following components by weight percentage: 10% metronidazole powder, 4% sulfur powder, 5% camphor, 33% clotrimazole cream, 26% micon Clotrimazole emulsifiable cream and 22% medical glycerin, wherein, metronidazole powder and sulfur powder pass through 60 mesh sieves, and the specification of clotrimazole emulsifiable paste is to contain 0.1g clotrimazole in every 10g clotrimazole emulsifiable paste, Manufacturer: Guangdong China Resources Shunfeng Pharmaceutical Co., Ltd.; the specification of miconazole clobetasol cream is that every 10g of miconazole clobetasol cream contains 0.2g miconazole nitrate and 5mg clobetasol propionate , Manufacturer: Guangzhou Dongkang Pharmaceutical Co., Ltd.; according to the preparation process of the aforementioned Example 1, the external pharmaceutical composition of the present invention was obtained.

[0041] For the external pharmaceutical compositio...

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Abstract

The invention discloses an external medicinal composition for treating dermatosis. The external medicinal composition consists of the following components in percentage by weight: 5 to 12 percent of metronidazole powder, 1 to 4 percent of sulphur powder, 1 to 5 percent of camphor, 25 to 33 percent of clotrimazole cream, 26 to 35 percent of compound miconazole nitrate cream or compound ketoconazole cream and 20 to 40 percent of glycerine for medical purposes. A preparation process comprises the following steps of (1) adding the metronidazole powder, the sulphur powder and the camphor into the glycerine for medical purposes, heating the components to 80 to 100 DEG C, and uniformly mixing the components; (2) sequentially adding the clotrimazole cream and the compound miconazole nitrate cream or the compound ketoconazole cream after the components in the step (1) are cooled to room temperature, and completely and uniformly stirring the components to obtain the external medicinal composition. The external medicinal composition for treating dermatosis is prepared from a plurality of components with sterilization and antibacterial effects, has the effects of resisting fungi and anaerobic bacteria and killing mites, and has remarkable curative effects on allergic dermatitis, contact dermatitis and skin disorder caused by various germs.

Description

technical field [0001] The invention relates to a medicine, in particular to a medicine for external use used for treating contact dermatitis, allergic dermatitis, and various skin diseases caused by fungi, anaerobic bacteria, and mite infections. The invention also relates to the medicine for external use method of preparation. Background technique [0002] Skin disease is a common multiple disease with a high incidence rate, which has seriously affected people's daily life and work. There are many kinds of skin diseases, the etiology is complicated, and it is difficult to cure them, which brings different degrees of distress to patients. Now on the market, there are many medicines for treating skin diseases, but most external medicines can only treat a specific skin disease, and the therapeutic effect is relatively poor for skin diseases caused by other etiology or multiple causes of disease; and Treat dermatosis by medicine for internal use, then can cause damage to bod...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/04A61P17/00A61K31/573A61K31/496A61K31/4174A61K31/4164A61K31/125
Inventor 陈嘉陵
Owner 陈嘉陵
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