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Externally-used medicine for treating stubborn ringworm and preparation method thereof

A technology for external medicine and stubborn tinea, applied in the field of external medicine for the treatment of stubborn tinea and preparation thereof, can solve the problems of slow effect, inability to achieve radical cure, poor effect, etc., and achieves strong anti-inflammatory, good anti-inflammatory effect, and low dosage Effect

Inactive Publication Date: 2017-12-08
王昌华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Current studies have found that metronidazole and fluocinonide have good bactericidal and anti-inflammatory effects, can treat rashes, and eliminate inflammation, but for stubborn ringworm, their effects are poor, and the effect is slow, and they cannot be cured
There are also several external medicines that are obtained by mixing, such as application number 200510022273.7, which discloses a plaster for the treatment of skin diseases, wherein it is formed by mixing dexamethasone acetate ointment and acyclovir ointment. cure

Method used

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  • Externally-used medicine for treating stubborn ringworm and preparation method thereof
  • Externally-used medicine for treating stubborn ringworm and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] An external medicine for treating intractable tinea, comprising 2% medicament and 98% cream;

[0024] The medicament comprises the following components, in parts by weight: 10 parts of 2-methyl-5-nitroimidazole-1-ethanol, 20 parts of dexamethasone acetate, 10 parts of cyproheptadine hydrochloride, 10 parts of fluocinolone acetate, amidium nitrate Conazole 10 parts, ketoconazole 15 parts, clobetasol propionate 0.5 parts, borneol 20 parts, medical starch 180 parts.

[0025] The emulsifiable paste comprises distilled water and the following component raw materials, and the raw materials are calculated by weight: 40 parts of paraffin oil, 1.2 parts of cetyl alcohol, 1.2 parts of anhydrous lanolin, 5.28 parts of Tween 80, 12 parts of Span 80, 5 parts of cooling oil , 4 parts of essence, 0.3 part of preservative, and 0.5 part of anti-oxidation.

[0026] The preparation method of the external medicine for the treatment of intractable ringworm, comprises the following steps: ...

Embodiment 2

[0031] An external medicine for treating intractable tinea, comprising 2% medicament and 98% cream;

[0032] The medicament includes the following components, in parts by weight: 15 parts of 2-methyl-5-nitroimidazole-1-ethanol, 20 parts of dexamethasone acetate, 5 parts of cyproheptadine hydrochloride, 5 parts of fluocinolone acetate, ammonium nitrate Conazole 5 parts, ketoconazole 12 parts, clobetasol propionate 0.4 parts, borneol 50 parts, medical starch 200 parts.

[0033] The emulsifiable paste comprises distilled water and the following component raw materials, and the raw materials are calculated by weight: 40 parts of paraffin oil, 1.2 parts of cetyl alcohol, 1.2 parts of anhydrous lanolin, 5.28 parts of Tween 80, 12 parts of Span 80, 5 parts of cooling oil , 4 parts of essence, 0.3 part of preservative, and 0.5 part of anti-oxidation.

[0034] The preparation method of the external medicine for the treatment of intractable ringworm, comprises the following steps:

[...

Embodiment 3

[0039] An external medicine for treating intractable tinea, comprising 2% medicament and 98% cream;

[0040] The medicament includes the following components, in parts by weight: 15 parts of 2-methyl-5-nitroimidazole-1-ethanol, 22 parts of dexamethasone acetate, 3 parts of cyproheptadine hydrochloride, 3 parts of fluocinolone acetate, ammonium nitrate Conazole 3 parts, ketoconazole 10 parts, clobetasol propionate 0.2 parts, borneol 40 parts, medical starch 200 parts.

[0041]The emulsifiable paste comprises distilled water and the following component raw materials, and the raw materials are calculated by weight: 40 parts of paraffin oil, 1.2 parts of cetyl alcohol, 1.2 parts of anhydrous lanolin, 5.28 parts of Tween 80, 12 parts of Span 80, 5 parts of cooling oil , 4 parts of essence, 0.3 part of preservative, and 0.5 part of anti-oxidation.

[0042] The preparation method of the external medicine for the treatment of intractable ringworm, comprises the following steps:

[0...

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Abstract

The invention discloses an externally-used medicine for treating stubborn ringworm and a preparation method thereof. The externally-used medicine comprises 2-3% of medicament and 97-98% of emulsifiable paste. The medicament comprises 2-methyl-5-nitroimidazole-1-ethanol, dexamethasone acetate, cyproheptadine hydrochloride, fluocinonide, miconazole nitrate, ketoconazole, clobetasol propionate, borneol and medical starch. Through scientific compatibility and mutual collaboration of the contents and proportions of all the components of the externally-used medicine for treating stubborn ringworm, the dosage is small, fungi can be quickly killed, itching is relived quickly, and stubborn ringworm is subjected to radical treatment; as for slight red and swollen symptoms cause by the fungi, itching is relived in the first day, the red and swollen symptoms disappear in the second day, and the color of the skin is changed; as for stubborn ringworm, such as psoriasis, existing for ages, the red and swollen symptoms are subsided within 3-5 days, after insistent applying for a month, reappearing of stubborn ringworm is avoided, and therefore radical treatment is achieved; and toxicity and irritation are small, dependence is avoided, the reappearing probability is small, the applicable range is wide, and the externally-used medicine can be used by pregnant women and children.

Description

technical field [0001] The invention relates to medicines for skin diseases, in particular to an external medicine for treating stubborn tinea and a preparation method thereof. Background technique [0002] Intractable ringworm such as psoriasis is a common chronic, relapsing, inflammatory skin disease. It is characterized by pimples and erythema of various sizes, covered with silvery white scales on the surface, with clear boundaries, and is more likely to occur on the scalp, extensor sides of the extremities and the back. Men outnumber women. In mild cases, it may manifest as several silver coin-sized plaques on the elbow and knees, and in severe cases, the skin of the whole body may also be involved. At present, intractable ringworm is mainly caused by fungi, but there is no effective cure. Current studies have found that metronidazole, fluocinonide, etc. have good bactericidal and anti-inflammatory effects, can treat rashes, and eliminate inflammation, but for stubbor...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4164A61K31/573A61K31/4418A61K31/58A61K31/4174A61K31/496A61K31/045A61P17/06A61P17/00A61P31/10
CPCA61K31/4164A61K9/0014A61K31/045A61K31/4174A61K31/4418A61K31/496A61K31/573A61K31/58A61K47/44A61K2300/00
Inventor 王昌华
Owner 王昌华
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