Liquid gel and preparation method thereof

A gel and liquid technology, which is applied in liquid delivery, pharmaceutical formula, emulsion delivery, etc., can solve the problems of vaginal flora imbalance, inability to effectively alleviate, and large component content, so as to reduce vaginal pH and improve vaginal cleanliness , Strong bactericidal effect

Active Publication Date: 2017-01-04
吉安市御美丽健康产业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, if oral medicine is used for treatment, firstly, the side effects are large, and secondly, it cannot directly act on the affected area, and the curative effect is not significant; Disadvantages: For exampl

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The composition of the gel comprises: 2 parts by weight of chitosan, 2 parts by weight of hypromellose, 2 parts by weight of polyethylene glycol 6000, 0.2 part by weight of chlorhexidine acetate, 0.15 parts by weight of carbomer, and 0.15 parts by weight of propylene glycol 2 parts by weight of hawthorn core, 1.5 parts by weight of hyaluronic acid, 0.02 part by weight of miconazole nitrate, 55 parts by weight of purified water, and a pH value of 6.5.

[0018] Specific steps include:

[0019] (1) Dissolve chitosan in purified water according to the formula ratio, and wait for use after fully swelling;

[0020] (2) Dissolve hyaluronic acid substances in purified water according to the formula ratio, fully swell and set aside;

[0021] (3) Mix the remaining other components in the formula ratio evenly;

[0022] (4) Add the solution obtained in steps (1)-(3) into the same container, stir and mix well, and adjust the pH value to obtain a gel product.

[0023] The sum of t...

Embodiment 2

[0025] The composition of the gel comprises: 1.5 parts by weight of chitosan, 1 part by weight of hypromellose, 1 part by weight of polyethylene glycol 6000, 0.2 parts by weight of chlorhexidine acetate, 0.3 parts by weight of carbomer, and 0.8 parts by weight of propylene glycol 1 part by weight of hawthorn core, 1 part by weight of hyaluronic acid, 0.025 part by weight of miconazole nitrate, 60 parts by weight of purified water, and a pH value of 77.

[0026] Method is with embodiment 1.

Embodiment 3

[0028] The composition of the gel comprises: 2 parts by weight of chitosan, 3 parts by weight of hypromellose, 2.5 parts by weight of polyethylene glycol 6000, 0.20 parts by weight of chlorhexidine acetate, 0.20 parts by weight of carbomer, and 0.6 parts by weight of propylene glycol Parts, 0.6 parts by weight of hawthorn core, 1.0 parts by weight of hyaluronic acid substances, 0.05 parts by weight of miconazole nitrate, 55 parts by weight of purified water, pH value 6.

[0029] Method is with embodiment 1.

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PUM

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Abstract

Provided are liquid gel and a preparation method thereof. The liquid gel is characterized in that the gel is prepared from 0.5-2.5 parts by weight of chitosan, 0.5-5 parts by weight of hydroxypropyl methylcellulose, 0.5-6 parts by weight of polyethylene glycol 6000, 0.1-0.3 part by weight of chlorhexidine acetate, 0.1-3 parts by weight of carbomer, 0.1-2 parts by weight of propylene glycol, 0.1-3 parts by weight of Chinese hawthorn seeds, 0.2-2 parts by weight of hyaluronic acid matter, 0.01-0.5 part by weight of miconazole nitrate and 50-70 parts by weight of purified water, and the pH ranges from 5 to 7.5. The liquid gel has the advantages of being small in side effect, good in treatment effect, not likely to cause genital tract flora unbalance and capable of effectively relieving or curing the disease.

Description

technical field [0001] The invention relates to the technical field of gel materials, in particular to a liquid gel and a preparation method thereof. Background technique [0002] With the change of life concept and the deterioration of the surrounding environment, reproductive tract infection has become more and more common and frequently-occurring diseases among women. It is mainly a kind of infectious disease that occurs in the female reproductive system, and is mainly transmitted through sexual channels, among which vaginitis is the most common. However, if oral medicine is used for treatment, firstly, the side effects are large, and secondly, it cannot directly act on the affected area, and the curative effect is not significant; Disadvantages: For example, the content of chemical reagents is large, and there are still relatively large side effects. In addition, it is easy to cause an imbalance of vaginal flora, which cannot effectively alleviate or cure the condition....

Claims

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Application Information

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IPC IPC(8): A61K36/734A61K9/06A61P31/10A61P31/04A61P15/02A61P15/00A61K31/722A61K31/4174A61K31/78
CPCA61K9/0034A61K9/06A61K31/4174A61K31/722A61K31/78A61K36/734A61K47/36A61K2300/00
Inventor 尹志明刘动勤
Owner 吉安市御美丽健康产业股份有限公司
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