Liquid gel and preparation method thereof
A gel and liquid technology, which is applied in liquid delivery, pharmaceutical formula, emulsion delivery, etc., can solve the problems of vaginal flora imbalance, inability to effectively alleviate, and large component content, so as to reduce vaginal pH and improve vaginal cleanliness , Strong bactericidal effect
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Embodiment 1
[0017] The composition of the gel comprises: 2 parts by weight of chitosan, 2 parts by weight of hypromellose, 2 parts by weight of polyethylene glycol 6000, 0.2 part by weight of chlorhexidine acetate, 0.15 parts by weight of carbomer, and 0.15 parts by weight of propylene glycol 2 parts by weight of hawthorn core, 1.5 parts by weight of hyaluronic acid, 0.02 part by weight of miconazole nitrate, 55 parts by weight of purified water, and a pH value of 6.5.
[0018] Specific steps include:
[0019] (1) Dissolve chitosan in purified water according to the formula ratio, and wait for use after fully swelling;
[0020] (2) Dissolve hyaluronic acid substances in purified water according to the formula ratio, fully swell and set aside;
[0021] (3) Mix the remaining other components in the formula ratio evenly;
[0022] (4) Add the solution obtained in steps (1)-(3) into the same container, stir and mix well, and adjust the pH value to obtain a gel product.
[0023] The sum of t...
Embodiment 2
[0025] The composition of the gel comprises: 1.5 parts by weight of chitosan, 1 part by weight of hypromellose, 1 part by weight of polyethylene glycol 6000, 0.2 parts by weight of chlorhexidine acetate, 0.3 parts by weight of carbomer, and 0.8 parts by weight of propylene glycol 1 part by weight of hawthorn core, 1 part by weight of hyaluronic acid, 0.025 part by weight of miconazole nitrate, 60 parts by weight of purified water, and a pH value of 77.
[0026] Method is with embodiment 1.
Embodiment 3
[0028] The composition of the gel comprises: 2 parts by weight of chitosan, 3 parts by weight of hypromellose, 2.5 parts by weight of polyethylene glycol 6000, 0.20 parts by weight of chlorhexidine acetate, 0.20 parts by weight of carbomer, and 0.6 parts by weight of propylene glycol Parts, 0.6 parts by weight of hawthorn core, 1.0 parts by weight of hyaluronic acid substances, 0.05 parts by weight of miconazole nitrate, 55 parts by weight of purified water, pH value 6.
[0029] Method is with embodiment 1.
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