61 results about "Light activated" patented technology

The application provides a function gradient doped slab laser device, and relates to the technical field of solid-state lasers.The device comprises a pump source, a pump light shaping element and a laser material.The pump light output by the pump source is guided into the laser material through the pump light shaping element, so that the pump light activates the active ions in the laser material to generate laser light.The doping concentration of the laser material satisfies a pre-set doping concentration function, which is used to represent that the materials at different positions in the laser material correspond to different doping concentrations.The technical scheme provided by the application precisely controls the doping concentration of the laser material.Under the condition that the total heat power is unchanged, the temperature distribution of the laser material along the thickness direction is closer to a uniform distribution state, the thermal gradient and thermal effect of the laser material can be reduced, the thermal deformation and thermal stress of the laser material caused by the temperature gradient can be reduced, and the stability and reliability of the function gradient doped slab laser device in operation can be improved.

The invention relates to a method and a system (10) for displaying a viewing direction-dependent view for a predetermined location. The predetermined location, including its surroundings, is captured from one or more viewing directions (15), with or without one or more objects (12) at the location. One or more objects (12) at the predetermined location are then obscured by a three-dimensional display device (20). Based on the images captured in the preparation phase (200), a display model is calculated. This model allows the predetermined location, including its surroundings, to be displayed using the light-activated elements (22) of the display device (20) for each of the one or more predetermined viewing directions (15) or for each viewing direction (15) within the one or more predetermined solid angles. In the absence of one or more objects (12), the location can be displayed from the respective viewing direction (15). In an application phase (206) a momentary viewing direction (15) is determined, a representation of the predetermined location together with its surroundings in the absence of one or more objects (12) is determined from the momentary viewing direction (15) by means of the display model and is displayed by means of the light-active elements (22) of the display device (20) in relation to the momentary viewing direction.

This medical system comprises: a balloon catheter having an elongate first shaft and a balloon attached to the first shaft, the balloon catheter being for delivering, to the blood vessel wall of a blood vessel, a drug that can be activated by light emitted from a light irradiation body inserted into a lumen extending through the first shaft; an ultrasonic probe having an elongate second shaft and ultrasonic elements attached to the second shaft, the ultrasonic probe being insertable into the lumen and for transmitting ultrasonic waves toward the blood vessel wall from a plurality of positions on the first shaft along the longitudinal direction thereof and receiving reflected waves of the ultrasonic waves using the ultrasonic elements; and a controller that acquires ultrasonic information relating to the reflected waves received by the ultrasonic elements, calculates the vascular stiffness of the blood vessel corresponding to each of the plurality of positions on the basis of the acquired ultrasonic information, and outputs the calculated vascular stiffness in association with each of the plurality of positions.

Provided herein are various examples of a method of coupling oligonucleotides to a polymer. The method may include selectively irradiating first inactive moieties in a one or more first region of a polymer with light, while not irradiating second inactive moieties in a one or more second region of the polymer, to generate first active moieties in the one or more first region of the polymer. The method may also include coupling the first active moieties to first oligonucleotides. The method may further include irradiating the second inactive moieties in the one or more second region of the polymer with light to generate second active moieties in the one or more second region of the polymer. The method may also include coupling the second active moieties to second oligonucleotides.

The invention relates to a preparation method of a heavy-atom-free photosensitizer based on a BODIPY dye, the photosensitizer comprises a thiocarbamate light cage, not only can generate singlet oxygen (1O2) under red light irradiation, but also can release carbonyl sulfide (COS), and generates hydrogen sulfide (H2S) under physiological conditions through carbonic anhydrase catalysis. By reasonably adjusting the molecular structure, the singlet oxygen quantum yield and hydrogen sulfide release efficiency of the photosensitizer are remarkably improved. The method is the first case which is reported at present and can simultaneously activate and release the organic optical functional micromolecules of H2S and 1O2 through a single beam of red light. The strategy effectively solves the problem of dependence on oxygen in type II photodynamic therapy (PDT), and further effectively improves the effect of PDT hypoxic tumors. In in-vitro and in-vivo experiments, hydrogen sulfide gas and photodynamic synergic treatment trigger pyroptosis of cells, promote maturation of dendritic cells and stimulate antitumor immune response. Therefore, the invention provides a synergistic treatment strategy combining gas, photodynamic and immunotherapy, and has a remarkable effect in the aspect of hypoxic tumor treatment. The photosensitizer material disclosed by the invention is simple to prepare and low in cost, has a wide application prospect, and particularly provides a solution with huge potential for cancer treatment in the field of biomedicine.

An Energy Reducing Maintenance Switch (ERMS) connected to an electrical circuit includes: a switch that activates the ERMS upon being closed or turned-on; a normally-open first contact that closes to activate an instantaneous trip setting of a relay upon activation of the ERMS; and a second contact. The instantaneous trip controls an arc flash in the electrical circuit, and the activated instantaneous trip setting of the relay reduces time of the arc flash in the electrical circuit. Upon activation of the ERMS, the second contact closes to initiate ERMS activation alert in two or more forms.

This invention discloses a photoactivated nanoparticle-based drug delivery material for immunoadjuvants, its preparation method, and its applications. The drug delivery material is constructed from photosensitizer monomers, crosslinking monomers, and immunoadjuvant prodrug monomers within a confined space of a nanoemulsion via a copper-free click polymerization reaction to form crosslinked polymer nanoparticles. The nanoparticle size is controllable, and the composition is precisely defined. Under physiological conditions, the drug delivery material exhibits good colloidal stability and high drug loading. Upon near-infrared light irradiation, the generated ROS can cleave the thioketone bonds, causing the nanoparticles to depolymerize and achieving photo-triggered, controllable release of the immunoadjuvant. Under photodynamic action, this drug delivery material efficiently generates reactive oxygen species to induce immunogenic cell death in tumor cells. Simultaneously, the released immunoadjuvant activates the TLR7 / 8 pathway, promotes dendritic cell maturation, and enhances the systemic anti-tumor immune response, thereby inhibiting the growth of tumors in situ and at distant sites, and reducing the risk of metastasis and recurrence.

The invention belongs to the technical field of phosphorescent materials and information encryption materials, and discloses a light activation time dependent afterglow carbon dot polymer film and a preparation method and application thereof.The preparation method comprises the following steps that o-phenylenediamine serves as a carbon source precursor, isopropanol serves as a solvent, a reaction is conducted for 6-8 h at the temperature of 180-250 DEG C under the closed high-pressure condition, and a CDs solution is obtained; and adding the CDs solution into the ABS resin, uniformly mixing to prepare a polymer film, and curing to obtain the ABS / CDs composite film. The obtained polymer film shows double light activated delayed luminescence, emission is generated at 521 nm and 652 nm respectively, the reversible afterglow discoloration process from red to orange to yellow to green is achieved, and the optical memory effect as long as 40 minutes is shown under the environmental condition. The method is a first carbon dot-based system which realizes a photo-activated TEAC behavior and has a reversible optical memory characteristic. Compared with inorganic and organic materials, the carbon dot polymer film has the advantages of simplicity, convenience, rapidness, no metal, long service life, economy, effectiveness, low toxicity and the like.

The application discloses a kind of photoactivation manganese ion bridging type deoxyribozyme probe preparation and its application in Cistanche inhibiting acetylcholinesterase activity.The probe is pSD@MnO2 Composite structure, which is composed of manganese dioxide nanosheet and functional nucleic acid assembly adsorbed on its surface, the assembly includes S chain labeled with fluorescence / quenching group and containing deoxyribozyme cleavage site, and pD chain partially hybridized with S chain and containing photocleavage site.Its preparation includes nucleic acid probe assembly, MnO2 Nanosheet complexing and purification steps.When applied, AChE catalytic product decomposes MnO2, releases Mn 2+ And nucleic acid chain; after centrifugation, pD chain is cut by ultraviolet light activation trigger, and released DNAzyme is cut under the assistance of Mn 2+ It produces amplified fluorescence signal; by comparing signal change before and after adding inhibitor, inhibition activity can be quantitatively evaluated.The application combines photocontrol activation with enzyme cascade amplification, realizes high sensitivity and operation synchronism of detection process, and is especially suitable for high-throughput rapid screening of AChE inhibitor in Cistanche and other natural products.

This invention discloses a two-dimensional hydrogen germanene nanosheet, its preparation method, and its applications. The two-dimensional hydrogen germanene nanosheet has an ultrathin layered structure, with covalently modified hydrogen atoms on its surface, a lateral dimension of 100–300 nm, and a thickness of 5–10 nm. When activated by a specific wavelength laser, the two-dimensional hydrogen germanene nanosheet can photoexcite and generate singlet oxygen to destroy bacterial biofilms and kill bacteria. Simultaneously, it consumes local oxygen to create a staged hypoxic microenvironment, thereby inhibiting excessive inflammatory responses. After the light exposure ends, as the local oxygen level naturally recovers, it can further enhance the infection clearance function of immune cells, achieving continuous clearance of residual infection. This invention, through staged dynamic regulation of oxygen partial pressure, synergistically integrates direct bactericidal and immune clearance processes, ensuring antibacterial strength while reducing the risk of tissue damage and infection recurrence. It is suitable for the safe and effective treatment of implant-related biofilm infections.

A sensor has a radiation emitter, a plurality of electrodes, a sensing material (transducer), and a recognition element (receptor, bioreceptor). The radiation element irradiates the sensing material, the plurality of electrodes are in electrical contact with the sensing material, and the recognition element is in contact, either directly or through an interface, with the sensing material. The sensing material receives radiation from the radiation source and interacts with the target material largely through the receptor. Further, the sensing material generates a measurable electrical signal upon interaction with a target molecule, when a potential is applied to the electrodes.

The invention discloses an antibody targeting light activated fluorescent protein Dronpa and related application thereof.The amino acid sequences of CDR-H1, CDR-H2 and CDR-H3 in a heavy chain variable region of the antibody are shown as SEQ ID NO.4-6 respectively, and the amino acid sequences of CDR-L1, CDR-L2 and CDR-L3 in a light chain variable region of the antibody are shown as SEQ ID NO.7-9 respectively. According to the antibody and the application thereof, accurate tool support is provided for detection and analysis of Dronpa protein, and the antibody can be applied to detection of Dronpa protein. Meanwhile, a key technical guarantee is provided for life science experiments (such as living cell imaging and molecular mechanism research) and potential clinical application based on the Dronpa protein.

The present disclosure provides an enhanced windshield display for a vehicle. An autonomous vehicle includes a window having a first polymeric material layer and a second polymeric material layer between an inner glass layer and an outer glass layer. The first polymer material layer includes perovskite crystals that are activated by UV light and emit visible light. The second polymer material layer is disposed between the outer glass layer and the first polymer material layer. The second polymer material layer blocks UV sunlight to prevent activation of the perovskite crystals. The vehicle also includes a projector configured to project UV light onto the inner side of the window to form a luminescent image on the window.

The application provides a novel light-activated channel protein VR3.0 and uses thereof. The light-activated channel protein VR3.0 series provided in this application has a wide range of photosensitive wavelengths, higher sensitivity to light response, faster photoresponse kinetics, maintaining stable photocurrent signals under high-frequency stimulation while exhibiting good response amplitude and frequency under light stimulation of various wavelengths (especially white light, natural light). The light-activated channel protein VR3.0 series provided in this application has a clear therapeutic effect on retinal photoreceptor cell degenerative diseases, and can be used to prepare drugs for restoring the photoreceptor function of the retina, restoring the visual or photosensitive ability of subjects, and treating retinal degenerative diseases.

This invention discloses an intelligent defect detection system and self-healing method for RFID tags on flexible substrates, belonging to the field of IoT electronic device manufacturing technology. The system integrates a high-resolution image acquisition module, a multispectral sensor array, and a robotic arm motion platform to construct a three-dimensional dynamic scanning system, capturing the surface and internal structural features of the flexible substrate in real time. A deep learning-based defect recognition algorithm, combined with multi-scale convolutional neural networks and transfer learning techniques, achieves accurate classification of 12 types of defects, including microcracks, conductive layer fractures, and substrate deformation, with a detection accuracy of 99.2%. A dual-mode self-healing mechanism is proposed: for conductive layer defects, nano-silver conductive colloid is injected through microfluidic channels, and 3D structural reconstruction is achieved using a controllable temperature field; for substrate damage, a photoresponsive shape memory polymer patch is used, which achieves molecular-level bonding repair after activation by ultraviolet light. This solution improves detection efficiency by more than 5 times, and the RF performance of the tag recovers to 98.7% of its initial value after self-healing.

The invention discloses a carborane fluorescent material as well as preparation and application thereof, and belongs to the technical field of photoelectric functional materials. The structural formula of the carborane fluorescent material is shown in the specification, and R comprises a fused ring aromatic group. The carborane fluorescent material provided by the invention has the characteristic of excitation dependence, the fluorescence emission spectrum of the carborane fluorescent material is remarkably changed along with the change of the wavelength of incident excitation light, and the carborane fluorescent material forms a distinct contrast with a traditional fluorescent material with a single emission wavelength; in addition, the carborane fluorescent material shows high fluorescence quantum yield, the technical defect that the fluorescence quantum yield of a traditional organic excitation dependent material is low is effectively overcome, and the fluorescence performance and the practical value are improved. Meanwhile, the material can be used for preparing carborane excitation dependent crystals and carborane excitation dependent fluorescent films with light activation characteristics, and the application range of the material in the field of photoelectric information is expanded.

The invention relates to a method for the extrinsic calibration of an interior camera in a vehicle, wherein the interior camera is first calibrated with respect to a reference coordinate system and the position of an interior light in the vehicle relative to the reference coordinate system is known. According to the invention, it is provided that: - a three-dimensional environmental model is created with respect to the vehicle based on signals acquired from an environmental sensor; - the interior light in a section is activated corresponding to a position of a three-dimensional object acquired in the environmental model; - a projection vector between a light point of the activated section of the interior light and the position of the acquired object is determined; - a corneal reflection image is determined based on acquired image data from the interior camera to be calibrated.- the determined projection vector is projected onto the corneal reflection image and a reference vector is determined, - a reflected light point of the ambient light activated relative to the object is detected in the corneal reflection image, - a deviation between the reflected light point and the reference vector is determined, - the deviation is evaluated with respect to a threshold value, and - if it is determined that the deviation exceeds the threshold value, extrinsic calibration parameters of the indoor camera are recalibrated.

The application discloses a kind of photoactivation biotin-biological orthogonal prodrug system and its anti-tumor application.The system integrates biotin targeting ligand, photo-caged tetrazine (TZ) group into one molecule through connecting chain, and can release activated TZ under specific wavelength light, then, TZ and trans-cyclooctene (TCO) modified prodrug or probe occur biological orthogonal reaction, realize the accurate release of tumor site.The system has the functions of active targeting, light-controlled rapid release and diagnosis and treatment integration, and has high tumor inhibition rate, which is significantly better than traditional chemotherapy, and has no obvious systemic toxicity, providing a new strategy for precise treatment of malignant tumors.

The invention provides a pollutant purification system and method based on an ultraviolet photocatalytic fuel cell. The purification system comprises a light focusing device and a photocatalytic fuel cell device, the photocatalytic fuel cell device comprises an anode chamber and a cathode chamber, and the anode chamber and the cathode chamber are connected through a liquid channel; an anode plate with a catalyst is arranged on one side, far away from the cathode chamber, of the anode chamber, a cathode electrode is arranged in the cathode chamber, and the anode plate is connected with the cathode electrode in the cathode chamber through a wire. By focusing sunlight, ultraviolet light activates the catalyst to generate holes and electrons; the wastewater in the anode chamber is oxidized by holes, electrons generate current, and the cathode electrode discharges and interacts with the wastewater with the oxidant in the cathode chamber to generate a purification effect.

A composite pane includes an outer pane having outer and inner surfaces, a first thermoplastic intermediate layer, a hologram element including a first set of holograms produced in one or more layers of a holographic material, wherein the first set of holograms includes a blue hologram that is activatable by blue light having a wavelength in a first range and is not responsive to light of other wavelengths, a green hologram that is activatable by green light having a wavelength in a second range and is not responsive to light of other wavelengths, and a red hologram that is activatable by red light having a wavelength in a third range and is not responsive to light of other wavelengths, an inner pane, and a color-selective optical filter for selective absorption of light.

A stroboscopic device to use a camera and a light source with software that generates synthetic and real video frames, compares the frames via a discriminator, repeat until a convergenc point is achieved where the discriminator can't reliably tell the real video frames from the synthetic video frames, analyzes a dense optical flow field between a first and second frame in a sequence of video frames to detect a motion, and controls a light activation to achieve a stroboscopic effect, wherein once achieved, a system identifies an object and automatically detects movement or vibration of the idenfied object using a trained model, enabling precise visualization and analysis of fast motions in video sequences.

The application discloses a kind of imide compounds for the photoactivation fluorescent detection method of opioid, comprising the following steps: S1, 1-100 equivalent imide compound, 10-10000 equivalent opioid and 0-100000 equivalent solvent are mixed, and mixture is prepared;S2, using 200nm-500nm light source or natural light is irradiated 5s-5000s to the mixture in S1 at room temperature, fluorescence phenomenon can be detected.This application will amide derivative (solid or liquid), opioid (solid or liquid) and solvent are mixed, under the irradiation of specific wavelength and power light source, imide molecule and the specific structure between drug molecule form similar to exciplex photo-irradiation product, the product will produce structure-dependent fluorescence, to carry out the specific recognition of drug molecule.The method is simple in operation, and sensitivity is high, specificity is strong, so opioid can be efficiently and rapidly qualitatively detected.

Various embodiments of the present technology may provide a valve assembly that activates chemistry using UV light. The valve assembly includes a primary valve manifold connected to secondary valve manifolds. A transparent connector may be disposed between the primary valve manifold and the secondary valve manifold. A UV light may be disposed adjacent to the transparent connector.

The invention relates to variants of light-sensitive ion channel protein ChRmine and application of the variants in treatment of retina neurodegenerative diseases. Compared with ChRmine, the variant has improved stability, expression efficiency and light activation characteristics in vivo, and can significantly improve the effect of treating retina neurodegenerative diseases.

The invention relates to biological application of binary system triplet-triplet annihilation up-conversion luminescence in Schiff base controllable photoisomerization based on a sleeve device, a binary up-conversion system is constructed through regulation and control of a photosensitizer and an annihilation agent, near-infrared light or long-wavelength visible light is converted into short-wavelength blue light, Trans-to-Cis isomerization of Schiff base is triggered, and reactive oxygen species are synchronously generated. An inner-outer double-layer sleeve closable structure is innovatively adopted, accurate regulation and control of the photosensitizer-annihilation agent proportion and independent separation of a substrate are achieved, the technology breaks through the biological penetration limitation of a short-wavelength light source, and a novel light-activated prodrug release strategy is provided for tumor targeted therapy.

The invention discloses a sliding texture sensor based on laser direct writing and a microstructure and a preparation method thereof, and belongs to the technical field of sliding sensing sensors. The sliding texture sensor comprises a substrate layer and a copper-plated pattern layer, wherein the substrate layer is of a three-dimensional structure with convex structures distributed on the surface; and the copper-plated pattern layer is formed on the side surface of the convex structure, is positioned in an area which is 30-80% of the height of the convex structure, and is obtained by carrying out laser etching by adopting a laser direct writing technology and then carrying out chemical copper plating growth. According to the invention, the light-activated catalyst is doped in the substrate layer, and after the light-activated catalyst is activated by laser, the light-activated catalyst and the chemical plating solution are subjected to a replacement reaction, so that the preparation of the copper layer on the substrate layer with the convex structure is realized, and the perception capability and the conductivity of the bionic skin are enhanced; protruding structures distributed in a controllable sliding sensing mode are distributed on the surface of the substrate layer, the protruding structures can be bent and deformed during sliding, then measured resistance is changed, and sliding sensing is achieved.

This invention provides a viscose spunlace nonwoven fabric finished with seaweed extract and its preparation method, belonging to the field of fiber production technology. The method includes the following steps: S1. Pre-treatment of the viscose spunlace nonwoven fabric: unwinding the finished viscose spunlace nonwoven fabric and activating surface groups with ultraviolet light for functional activation; pre-wetting the viscose spunlace nonwoven fabric with pure water atomization to eliminate static electricity and ensure uniform spraying of the seaweed extract, preventing functional agents from adhering only to the surface; after ultraviolet light activation and pre-wetting treatment, this invention uses a uniform spray finishing process to load the natural seaweed extract onto the nonwoven fabric, followed by drying and fixing to impart multiple functional properties to the substrate, including moisturizing, antibacterial, and non-irritating properties.

The application belongs to the field of nanomaterials and biotechnology, and particularly relates to preparation of photo-activated oxidase-like gold nanoclusters and application of the same in biological thiol analysis. An alkaline solution of 6-methyl-2-thiouracil is added to a chloroauric acid solution, the product is purified by ultrafiltration centrifugation after stirring reaction at room temperature to obtain photo-activated oxidase-like gold nanoclusters. The photo-activated oxidase-like gold nanoclusters have an enzyme activity "switch" caused by photo-activation, so that the reaction is controllable, the enzyme-like activity is high, excellent enzyme-like activity can be obtained for biological detection at a sample concentration of only 100 μg / mL, and the photo-activated oxidase-like gold nanoclusters have good stability, so that simple, rapid, efficient and sensitive biochemical analysis biosensing, biochemical analysis and drug treatment can be established.

Laser-emitting medical devices and techniques that may be implemented by laser-emitting medical devices to determine when an optical fiber is disposed within an endoscope are described herein. Devices and techniques for determining the position of an endoscope are based on light received by an optical fiber from an endoscope floodlight located on a distal end of the endoscope. The activation device enables the laser emission, and the computing system interrupts the laser emission procedure if the fiber enters the endoscope.

An autonomous vehicle includes a window having first and second layers of polymer material between inner and outer layers of glass. The first layer of polymer material includes perovskite crystals that are activated by UV light and emit visible light. The second layer of polymer material is disposed between the outer layer of glass and the first layer of polymer material. The second layer of polymer material blocks UV sunlight to prevent activation of the perovskite crystals. The vehicle further includes a projector that is configured to project UV light onto the inside of the window to form illuminated images on the window.