The invention discloses a liquid phase chromatographic sample manager. According to a greatest innovation point of the invention, two two-position six-way valves, a two-position three-way valve, a two-position T-shaped valve and a distribution proportional electromagnetic valve are adopted to be interchanged and matched with one another, so that a sample derivation function, a sample feeding analysis function, a fraction collection function and a collection nitrogen-blowing concentration function can be satisfied. By designing two injectors, a sampling injector can be used for precisely feeding a sample, transferring the sample and deriving the sample, and a solvent injector can be used for replacing and washing solvent, so that the accuracy of instruments can be greatly improved, the abrasion of the sampling injector can be reduced, and the service life can be prolonged. According to the arrangement, the solvent of a random type in four solvent bottles can be mixed in a random ratio to form a solution, the accuracy is high, the use of the solvent can be determined according to the demand, the waste of solvent is avoided, the application cost of the solvent is reduced, and the environment pollution is reduced.