6 results about "Topical ointment" patented technology

This application relates to the field of pharmaceutical technology, and in particular to a topical ointment formulation and its preparation method. The formulation uses Sonicate as the active ingredient, combined with petrolatum, liquid paraffin, a solubilizing and penetration-enhancing system, and emulsifiers as excipients, to form an O / W type cream, an oil-based or water-soluble ointment. The preparation process employs a low-temperature dosing method at 40°C to ensure drug activity and inhibit crystallization. This application achieves high-concentration retention in local skin tissue through topical administration, significantly reducing radiation damage scores and pathological damage, while resulting in extremely low systemic plasma exposure, avoiding the systemic toxicity of oral administration, and providing a safe and efficient means for the clinical prevention and treatment of radiation-induced skin damage.

This invention discloses a topical ointment for treating lumbar disc herniation and vertebral joint pain, and its preparation method. The ointment is prepared from Strychnos nux-vomica, Spatholobus suberectus, Polygonum cuspidatum, Acorus tatarinowii, Clematis chinensis, white wine, Asarum heterotropoides, frankincense, myrrh, cinnamon twig, Achyranthes bidentata, Pueraria lobata, Lycopodium clavatum, and excipients honey and petrolatum. The preparation method is as follows: Strychnos nux-vomica, Spatholobus suberectus, Polygonum cuspidatum, Acorus tatarinowii, and Clematis chinensis are soaked in white wine for one year to obtain a medicinal wine concentrate; Asarum heterotropoides, frankincense, myrrh, cinnamon twig, Achyranthes bidentata, Pueraria lobata, and Lycopodium clavatum are ground into a fine powder and mixed evenly to obtain a medicinal powder; the obtained medicinal powder is moistened with the medicinal wine concentrate, and honey and petrolatum are added and mixed evenly. Existing typical clinical cases show that the ointment of this invention has no side effects, can effectively relieve the symptoms of lumbar disc herniation, and the pain disappears after use with no long-term recurrence, demonstrating significant efficacy and ease of use.

This invention belongs to the field of medical and nursing care products technology, specifically relating to a traditional Chinese medicine composition for chronic wounds that promotes antibacterial and tissue regeneration, and its application. The raw materials for this composition include Paris polyphylla, dragon's blood, frankincense, myrrh, rhubarb, Phellodendron bark, calamine, pearl powder, Oroxylum indicum, sappanwood, and Rosa laevigata leaves. When this traditional Chinese medicine combination is prepared into a topical ointment and applied to the wound, it possesses potent antibacterial, blood-activating, and tissue-regenerating effects, achieving simultaneous intervention at multiple stages. This improves wound healing and treatment outcomes, addressing issues such as bacterial resistance, insufficient regenerative capacity of modern dressings, and insufficient early-stage antibacterial and anti-inflammatory effects in existing chronic wound treatments. This provides a safe, effective, and economical new treatment option for clinical practice.

The application discloses a kind of external formula for bacteriostatic anti-inflammatory and treating scald and preparation device thereof, including yellow wax 31.2 parts, camphor oil 40.2 parts, pearl powder 14 parts, sanqi powder 14 parts, phenol 0.3 parts, chloramine acid 0.3 parts, the yellow wax is royal jelly wax, the camphor oil is refined sesame oil, the pearl powder is nanoscale pearl powder, the sanqi powder is superfine sanqi powder, the phenol and chloramine acid are all medicinal grade raw materials;The bacteriostatic anti-inflammatory effect of external ointment prepared by the present formula is remarkable, the bacteriostatic rate of staphylococcus aureus, escherichia coli, pseudomonas aeruginosa and candida albicans is all ≥99.5%, and the bacteriostatic ring diameter is better than existing sulfadiazine silver ointment, while having good quick anti-inflammatory effect, accelerates the healing time of Ⅱ degree scald wound, reduces scar formation rate, while greatly reducing local irritation and allergic reaction, far lower than existing western medicine, with good wound healing and safety advantage.

This invention provides a topical ointment containing Yunnan white pearl powder, its preparation method, and its application, belonging to the field of traditional Chinese medicine. By incorporating myrrh extract, scutellaria baicalensis extract, and ceramides, the synergistic effect of these active ingredients not only achieves the basic effects of anti-inflammatory, antibacterial, and skin barrier repair, but also unexpectedly enhances the transdermal absorption rate of Yunnan white pearl powder essential oil, strengthens its anti-inflammatory effect, reduces irritation, and extends its shelf life. Furthermore, it can inhibit post-inflammatory hyperpigmentation, with effects far exceeding the combined efficacy of individual ingredients and conventional compound formulations.

Described herein are ointment formulations for delivering active pharmaceutical agents to skin and particularly to hair follicles in skin. Methods of using the described ointment formulation for inhibiting the activity of epidermal growth factor receptor (EGFR) inhibitors, such as but not limited to treatments for EGFR-associated cancers, are also described.