14 results about "Topical ointment" patented technology

This application relates to the field of pharmaceutical technology, and in particular to a topical ointment formulation and its preparation method. The formulation uses Sonicate as the active ingredient, combined with petrolatum, liquid paraffin, a solubilizing and penetration-enhancing system, and emulsifiers as excipients, to form an O / W type cream, an oil-based or water-soluble ointment. The preparation process employs a low-temperature dosing method at 40°C to ensure drug activity and inhibit crystallization. This application achieves high-concentration retention in local skin tissue through topical administration, significantly reducing radiation damage scores and pathological damage, while resulting in extremely low systemic plasma exposure, avoiding the systemic toxicity of oral administration, and providing a safe and efficient means for the clinical prevention and treatment of radiation-induced skin damage.

The invention belongs to the technical field of external-use ointment, and particularly relates to external-use antibacterial ointment for skin and a preparation method of the external-use antibacterial ointment. The external antibacterial cream for the skin is prepared from the following raw materials in parts by weight: 120 to 210 parts of plant extract and 500 to 550 parts of base component. The plant extract comprises a xanthoceras sorbifolia extract, a cacumen biotae extract, a herba schizonepetae extract, a clove extract, a centella asiatica extract, a cortex phellodendri extract, a fructus chebulae extract, a fructus gardeniae extract, a liquorice extract and an aloe extract. Plant extracts are selected as main effective components, and the product is high in bacteriostasis rate, high in long-term storage stability, free of skin irritation and heavy metal residues and suitable for being used by people with various skin types, especially sensitive skin for a long time.

This invention discloses a topical ointment for treating lumbar disc herniation and vertebral joint pain, and its preparation method. The ointment is prepared from Strychnos nux-vomica, Spatholobus suberectus, Polygonum cuspidatum, Acorus tatarinowii, Clematis chinensis, white wine, Asarum heterotropoides, frankincense, myrrh, cinnamon twig, Achyranthes bidentata, Pueraria lobata, Lycopodium clavatum, and excipients honey and petrolatum. The preparation method is as follows: Strychnos nux-vomica, Spatholobus suberectus, Polygonum cuspidatum, Acorus tatarinowii, and Clematis chinensis are soaked in white wine for one year to obtain a medicinal wine concentrate; Asarum heterotropoides, frankincense, myrrh, cinnamon twig, Achyranthes bidentata, Pueraria lobata, and Lycopodium clavatum are ground into a fine powder and mixed evenly to obtain a medicinal powder; the obtained medicinal powder is moistened with the medicinal wine concentrate, and honey and petrolatum are added and mixed evenly. Existing typical clinical cases show that the ointment of this invention has no side effects, can effectively relieve the symptoms of lumbar disc herniation, and the pain disappears after use with no long-term recurrence, demonstrating significant efficacy and ease of use.

This invention belongs to the field of medical and nursing care products technology, specifically relating to a traditional Chinese medicine composition for chronic wounds that promotes antibacterial and tissue regeneration, and its application. The raw materials for this composition include Paris polyphylla, dragon's blood, frankincense, myrrh, rhubarb, Phellodendron bark, calamine, pearl powder, Oroxylum indicum, sappanwood, and Rosa laevigata leaves. When this traditional Chinese medicine combination is prepared into a topical ointment and applied to the wound, it possesses potent antibacterial, blood-activating, and tissue-regenerating effects, achieving simultaneous intervention at multiple stages. This improves wound healing and treatment outcomes, addressing issues such as bacterial resistance, insufficient regenerative capacity of modern dressings, and insufficient early-stage antibacterial and anti-inflammatory effects in existing chronic wound treatments. This provides a safe, effective, and economical new treatment option for clinical practice.

The invention discloses a skin lesion repairing ointment and a preparation method thereof, and belongs to the technical field of medicines, and the skin lesion repairing ointment is prepared from the following raw materials: periplaneta americana, purslane, golden cypress, scutellaria baicalensis and radix sophorae flavescentis. Tests show that the skin lesion repairing ointment has the same curative effect as the compound dexamethasone acetate cream and the recombinant bovine basic fibroblast growth factor gel on skin lesion treatment, and the curative effect is more lasting. However, the specific action mechanism is still unclear, and further research is needed. In the aspect of safety, the skin lesion repairing ointment group and the compound dexamethasone acetate cream and recombinant bovine basic fibroblast growth factor gel group do not have adverse reaction, so that the external ointment and the compound dexamethasone acetate cream and recombinant bovine basic fibroblast growth factor gel group are relatively safe.

The application discloses a kind of external formula for bacteriostatic anti-inflammatory and treating scald and preparation device thereof, including yellow wax 31.2 parts, camphor oil 40.2 parts, pearl powder 14 parts, sanqi powder 14 parts, phenol 0.3 parts, chloramine acid 0.3 parts, the yellow wax is royal jelly wax, the camphor oil is refined sesame oil, the pearl powder is nanoscale pearl powder, the sanqi powder is superfine sanqi powder, the phenol and chloramine acid are all medicinal grade raw materials;The bacteriostatic anti-inflammatory effect of external ointment prepared by the present formula is remarkable, the bacteriostatic rate of staphylococcus aureus, escherichia coli, pseudomonas aeruginosa and candida albicans is all ≥99.5%, and the bacteriostatic ring diameter is better than existing sulfadiazine silver ointment, while having good quick anti-inflammatory effect, accelerates the healing time of Ⅱ degree scald wound, reduces scar formation rate, while greatly reducing local irritation and allergic reaction, far lower than existing western medicine, with good wound healing and safety advantage.

This invention provides a topical ointment containing Yunnan white pearl powder, its preparation method, and its application, belonging to the field of traditional Chinese medicine. By incorporating myrrh extract, scutellaria baicalensis extract, and ceramides, the synergistic effect of these active ingredients not only achieves the basic effects of anti-inflammatory, antibacterial, and skin barrier repair, but also unexpectedly enhances the transdermal absorption rate of Yunnan white pearl powder essential oil, strengthens its anti-inflammatory effect, reduces irritation, and extends its shelf life. Furthermore, it can inhibit post-inflammatory hyperpigmentation, with effects far exceeding the combined efficacy of individual ingredients and conventional compound formulations.

Described herein are pharmaceutical compositions comprising a bis(pyridine) antimicrobial agent, or an octenidine-based compound, formulated as a topical ointment. Also described here are methods of use of bis(pyridine) antimicrobial agents, or an octenidine-based compounds, for use in methods of wound healing and methods of reducing or preventing infection in a subject.

The invention discloses a preparation method of an abelmoschus manihot composition psoriasis external ointment, and relates to the technical field of psoriasis ointment preparation. Comprising the following steps: raw material compatibility and pretreatment: taking 10-30 parts by mass of abelmoschus manihot, 8-20 parts by mass of salvia miltiorrhiza, 5-15 parts by mass of gentiana macrophylla, 5-15 parts by mass of fried stiff silkworm, 5-15 parts by mass of ginseng, 1-5 parts by mass of prepared cantharides, 2-8 parts by mass of camphor crystals, 2-8 parts by mass of borneol, 3-10 parts by mass of mint crystals, 20-40 parts by mass of pure mutton fat and 10-30 parts by mass of olive oil. The borneol is guided into the skin, and all the medicinal materials have a synergistic effect and have a treatment effect on multiple links such as inflammation, hyperplasia and pruritus of psoriasis; a superfine grinding technology is adopted, so that the dissolution rate of effective components is greatly improved; the extraction efficiency is ensured and the loss of volatile components is avoided by adopting a segmented cooking process; the uniformity and the stability of the ointment are ensured by programmed cooling; the pure mutton fat and the olive oil are used as substrates, so that the skin affinity and the permeability are good.

The invention relates to the technical field of external ointment, in particular to turpinia arguta ointment and a preparation method thereof. The traditional Chinese medicine composition is mainly prepared from the following raw materials in parts by weight: 1-3 parts of turpinia arguta leaf extract; 8-12 parts of tea oil; 1-4 parts of camphor tree essential oil; 1-5 parts of natural beeswax; the total asiaticoside is strategically introduced into a traditional anti-inflammatory analgesic system composed of the turpinia arguta leaf extract, the tea oil, the camphor tree essential oil and the natural beewax, and the stability of active ingredients in the turpinia arguta ointment is improved through the preparation method, so that the turpinia arguta ointment has the instant effects of rapidly resisting bacteria and diminishing inflammation and relieving swelling and pain; the invention relates to a multifunctional external preparation which can be used for promoting fibroblast proliferation and collagen ordered synthesis, actively accelerating wound healing and remarkably inhibiting scar formation, so that on the premise of ensuring excellent storage stability and use safety, the function span from pure symptom control to active tissue repair is realized.

The present invention relates to ጸ herbal dietary supplement formulated to support overall well-being by promoting healthy libido, reducing inflammation and alleviating discomfort. The supplement comprises natural powders or extracts ዐ Trbulus terrestris (200-600 mg), Moringa oleifera (100-400mg), Zingiber officinale (ginger) (50-200 mg), and Salvia rosmarinus (rosemary) (50-150 mg), combined with natural shelf-life stabilizers. The preparation process involves collecting’ / harvesting, drying, milling, extracting with suitable solvents, concentrating and stabilizing the extracts to preserve bioactive constituents. The supplement can ከ6 formulated as powders, capsules, tablets, topical ointments and tea providing a natural approach to support sexual vitality, manage inflammation and promote comfort.

The health-care preparation comprises the surfactant provided by the invention and an active ingredient prepared into a solid, a liquid or an emulsion. The invention provides a preparation of a health care product, such as prescription medicine and non-prescription medicine. Mineral, herbal and / or vitamin supplements; medicaments applied in hospitals, clinics, doctor offices and nightseeing care places; vaccines, tissues, organs and cell grafts and / or substitutes and / or infusion agents; and wound care formulations including topical ointments, lotions, cleaners, wipes, bandages, and dressings. The active may be included in the formulation as a solute, solvent, particle, or oil immiscible component of the formulation. The active may be included in a tablet, capsule, tincture, liquid or emulsion. Healthcare formulations of the present invention include formulations suitable for oral, topical and / or injection administration.

Described herein are ointment formulations for delivering active pharmaceutical agents to skin and particularly to hair follicles in skin. Methods of using the described ointment formulation for inhibiting the activity of epidermal growth factor receptor (EGFR) inhibitors, such as but not limited to treatments for EGFR-associated cancers, are also described.

The invention discloses an application of a CK2 inhibitor CX4945 in preparation of medicines for treating skin inflammations such as psoriasis and the like. The CK2 inhibitor CX4945 ointment provided by the invention can be used for remarkably reducing the pathological injury of the skin of a psoriasis mouse and reducing the neutrophil infiltration of the dermis layer of the skin. The medicine can be prepared into external ointment, is locally applied for use, is convenient to use, has no obvious side effect, is high in patient compliance, and can be prepared into a psoriasis treatment medicine.