31 results about "Strychnos" patented technology

The invention discloses nux vomica for intervening in rheumatoid arthritis and a processing method and application thereof, and belongs to the technical field of traditional Chinese medicinal material processing. The processing method comprises the following steps: decocting crude semen strychni with a water decoction of rhizoma atractylodis macrocephalae, filtering, and drying filter residues to obtain the processed semen strychni. According to the processing method, the medicine effect and safety of the semen strychni are remarkably improved through the unique processing technology that the rhizoma atractylodis macrocephalae water decoction is adopted to decoct the semen strychni crude product, the original anti-inflammatory, analgesic and immunoregulation activity of the rhizoma atractylodis macrocephalae and the semen strychni crude product are reserved, the synergistic interaction effect is generated, the toxicity of the semen strychni is systematically reduced, and the effect is remarkable. The pharmaceutical safety is greatly improved while the treatment effect is enhanced, and the pharmaceutical composition has important clinical application value and market prospect.

The application belongs to the field of traditional Chinese medicines, and particularly relates to a more low-irritation analgesic ancient prescription microemulsion gel and application thereof in anti-arthritis drugs. The application finds that after water-soluble and fat-soluble components of black plaster prepared from raw frankincense, myrrh, eaglewood, dragon's blood, Strychnos nux-vomica, Panax notoginseng, Oldenlandia diffusa, Venenum Bufonis, bovine bezoar, Stachys jamaicensis, Platycodon grandiflorum, Hirudo nipponia, Tinea, Solenopsis geminata, Scorpio, scorpio, red lead and sesame oil are extracted, a more low-irritation analgesic ancient prescription microemulsion gel is prepared; compared with the black plaster itself, the analgesic effect of the microemulsion gel is significantly improved, and the microemulsion gel has good anti-inflammatory effect and can be used for preparing anti-arthritis drugs; and the microemulsion gel has reduced toxicity and is more convenient to use.

The invention belongs to the technical field of external traditional Chinese medicine ointment, and particularly relates to traditional Chinese medicine ointment for treating arthralgia. The traditional Chinese medicine composition specifically comprises the following raw materials: ground beetles, saline scorpions, centipedes, leeches, earthworms, silkworm larva, cantharides, rhizoma drynariae, shelled semen strychni, corydalis amabilis, peach kernels, saffron crocus, notopterygium roots, gentiana macrophylla, trogopterus dung, buttercup, cottonrose hibiscus leaves, borneol and musk. According to the invention, synergy of insect drugs and botanical drugs for dispelling wind and promoting blood circulation is taken as a core, and the composition is adapted to complex syndromes of arthralgia. The problems of component inactivation, degradation and insufficient extraction are avoided by adopting split-phase extraction; controlled-release microcapsules are separately arranged for high-risk groups such as cantharides to reduce stimulation and slow release, borneol and musk are included to increase stability, and infiltration promotion and slow release are complementary; an oil-water system is constructed by the cream matrix, and the cream has sealing performance, spreadability and residence performance and is suitable for external massage.

This invention belongs to the technical field of skin disease treatment products, specifically relating to a topical hot compress for treating scleroderma and its preparation method. The topical hot compress for treating scleroderma is made from the following raw materials in parts by weight: 20-40 parts of Artemisia argyi, 20-40 parts of Cinnamomum cassia, 10-20 parts of Sparganium stoloniferum, 10-20 parts of Curcuma zedoaria, 10-20 parts of Loranthus parasiticus, 15-30 parts of Gynostemma pentaphyllum, 10-20 parts of Spirodela polyrhiza, 15-30 parts of Spirodela polyrhiza, 15-30 parts of Ephedra sinica, 20-40 parts of Clematis chinensis, 5-15 parts of Eupolyphaga sinensis, 15-25 parts of Eriocaulon buergerianum, 5-15 parts of Carthamus tinctorius, 3-6 parts of Dracaena cochinchinensis, 3-6 parts of processed Strychnos nux-vomica, 20-40 parts of Vaccaria segetalis, 20-40 parts of Astragalus membranaceus, 10-20 parts of Magnolia officinalis, 10-20 parts of Aconitum carmichaelii, and 22-40 parts of rice wine. This invention is a topical medication that eliminates the need for oral administration, treating the disease externally and guiding the pathogenic factors to a cure. It avoids the inconvenience of bitter medications and effectively relieves symptoms and promotes the cure of localized scleroderma.

The invention discloses traditional Chinese medicine external medicinal liquor for treating bone diseases and a preparation method and application thereof. The medicinal liquor is prepared from, by weight, 30 g of ginseng under forest, 60 g of raw radix astragali, 90 g of dragon's blood, 60 g of sargentgloryvine stem, 30 g of radix clematidis, 60 g of radix angelicae, 30 g of scorpion, 60 g of lumbricus, 60 g of dried river crab, 30 g of silkworm larva, 60 g of ground beetle, 30 g of frankincense, 30 g of myrrh, 60 g of teasel root and 60 g of rhizoma drynariae. The traditional Chinese medicine is prepared from 60 g of native copper, 30 g of amber, 30 g of pericarpium zanthoxyli, 25 g of radix aconiti, 25 g of radix aconiti agrestis, 60 g of caulis spatholobi, 30 g of cortex erythrinae, 45 g of semen strychni, 15 g of musk and 30 g of borneol. The medicinal liquor achieves the effects of rapidly relieving swelling and pain, promoting bone healing, dispelling wind and eliminating dampness and the like through the synergistic effect of multiple targets, is especially suitable for arthralgia type osteoarticular diseases and traumatic injuries, and has remarkable curative effects on osteoproliferation, fracture recovery and the like and high safety according to clinical cases.

The invention discloses pine-soot ink moxibustion as well as a preparation method and a use method thereof, and relates to the technical field of traditional Chinese medicine moxibustion therapy. Comprising the following raw materials: pine-soot ink, tourmaline powder, radix aconiti preparata, semen strychni preparata, sanguisorba officinalis, rhizoma corydalis, pseudo-ginseng, angelica sinensis, safflower carthamus, ligusticum wallichii, radix saposhnikoviae, gastrodia elata, frankincense, earthworm, herba epimedii, dogwood, lucid ganoderma, astragalus membranaceus, gynostemma pentaphyllum, artificial musk, wintergreen oil, borneol and beautifying wax. According to the pine-soot ink moxibustion and the preparation method and the use method thereof, the pine-soot ink is used as a substrate, the tourmaline powder is compounded, and a raw material system of multiple traditional Chinese medicines is selected, so that the product not only has the hot compress and pharmacodynamic permeation functions of the traditional Chinese medicines, but also has the adsorption characteristic of the pine-soot ink and the physical effects of negative ion release and far infrared effect generation of tourmaline; multiple synergy of a drug therapy and a physical therapy is realized, so that better health-care effects of relaxing tendons and activating collaterals, dispelling cold and removing dampness and relieving bone and joint pain are achieved.

The present application relates to the technical field of medicine, and especially relates to a combined Chinese and western medicine composition and application thereof, wherein the combined Chinese and western medicine composition comprises Chinese patent medicine and western medicine; the raw material of the Chinese patent medicine comprises Strychnos seed powder, Earthworm, Codonopsis, Poria cocos, Atractylodes, Chuanxiong, Salvia miltiorrhiza, Panax notoginseng, Radix et Rhizoma Bovis, and Radix Glycyrrhizae; and the effective component of the western medicine is diclofenac; the application of the combined Chinese and western medicine composition in preparation of a lumbar pain medicine; the application is for preparation of intervertebral disc-derived lumbar pain medicines of different syndromes; the syndrome is preferably qi and blood deficiency syndrome; the combined Chinese and western medicine composition can effectively treat intervertebral disc-derived lumbar pain of different syndromes through mutual cooperation between the Chinese patent medicine and the western medicine, and the curative effect is more obvious for intervertebral disc-derived lumbar pain of qi and blood deficiency syndrome.

This invention discloses a topical ointment for treating lumbar disc herniation and vertebral joint pain, and its preparation method. The ointment is prepared from Strychnos nux-vomica, Spatholobus suberectus, Polygonum cuspidatum, Acorus tatarinowii, Clematis chinensis, white wine, Asarum heterotropoides, frankincense, myrrh, cinnamon twig, Achyranthes bidentata, Pueraria lobata, Lycopodium clavatum, and excipients honey and petrolatum. The preparation method is as follows: Strychnos nux-vomica, Spatholobus suberectus, Polygonum cuspidatum, Acorus tatarinowii, and Clematis chinensis are soaked in white wine for one year to obtain a medicinal wine concentrate; Asarum heterotropoides, frankincense, myrrh, cinnamon twig, Achyranthes bidentata, Pueraria lobata, and Lycopodium clavatum are ground into a fine powder and mixed evenly to obtain a medicinal powder; the obtained medicinal powder is moistened with the medicinal wine concentrate, and honey and petrolatum are added and mixed evenly. Existing typical clinical cases show that the ointment of this invention has no side effects, can effectively relieve the symptoms of lumbar disc herniation, and the pain disappears after use with no long-term recurrence, demonstrating significant efficacy and ease of use.

The invention provides Chinese herbal medicine oil for improving body immunity, and relates to the technical field of traditional Chinese medicine preparation. The Chinese herbal medicine oil for improving body immunity comprises mint, girald daphne bark, centella asiatica, berchemia sinica, saffron crocus, flos rhododendri mollis, semen strychni, radix aconiti agrestis, vernonia graveolens, ginger, caulis spatholobi, rhizoma drynariae, angelica sinensis, radix aconiti, frankincense, myrrh, gastrodia elata, ligusticum wallichii, radix angelicae pubescentis, cortex acanthopanacis, codonopsis pilosula, radix clematidis, asarum, elecampane, rhizoma atractylodis macrocephalae and teasel. By following the compatibility principle of monarch, minister, assistant and guide in traditional Chinese medicine, the formula contains multiple medicinal materials capable of strongly expelling wind and removing cold and activating meridians to stop pain, and also contains medicinal materials capable of promoting blood circulation to remove blood stasis and tonifying liver and kidney, purgation and tonification are combined, both symptoms and root causes are treated, the pathogenesis of arthralgia is very accurate, the immunity of a human body can be improved, and by using the whole links of soaking, frying, filtering, squeezing and aging, the arthralgia treatment effect is improved. About 15%-20% of medicinal oil adsorbed in the medicinal materials can be recycled, the overall quality is improved, the properties of the medicinal materials can be fused through curing, the medicinal materials become mellow, and irritation is reduced.

The invention discloses a traditional Chinese medicine composition which comprises the following medicinal materials in terms of 50 preparation units: 60-100 parts of pseudo-ginseng, 60-100 parts of vinegar-processed rhizoma corydalis, 20-60 parts of starfish, 20-60 parts of ground beeltle, 5-15 parts of processed semen strychni, 10-30 parts of safflower, 1-20 parts of vinegar-processed frankincense, 1-20 parts of vinegar-processed myrrh, 1-10 parts of borneol and 0.1-1 part of artificial musk. The invention further discloses a preparation method of a tincture of the traditional Chinese medicine composition and application of the traditional Chinese medicine composition in preparation of medicines for treating acute and chronic falling trauma, neck, shoulder, waist and knee pain or arthralgia. The traditional Chinese medicine composition disclosed by the invention has the effects of relaxing muscles and tendons, promoting blood circulation, dredging collaterals, dissipating blood stasis, diminishing swelling and relieving pain. Pharmacodynamic studies show that the traditional Chinese medicine composition disclosed by the invention takes effect quickly and has a good curative effect when being used for treating symptoms such as traumatic injuries, blood stasis swelling and swelling and red and swollen injuries. The traditional Chinese medicine composition disclosed by the invention effectively relieves the injury condition of a tested animal, and is free of irritation and sensitization to the tested animal in a skin medication toxicity test.

The invention relates to the technical field of plasters, and discloses a black plaster containing far infrared ceramic powder and a preparation method thereof, the black plaster comprises sesame oil, pangolin and turtle shell; the traditional Chinese medicine is prepared from radix aconiti, radix aconiti lateralis preparata, semen strychni, fructus amomi rotundus, radix aconiti kusnezoffii, semen persicae, cassia twig, honeycomb, flos carthami, herba lycopodii, garden balsam stem, radix rehmanniae, herba aristolochiae mollissimae, root placenta, radix saposhnikoviae, cortex phellodendri, radix angelicae, radix puerariae, radix angelicae sinensis, radix achyranthis bidentatae and rhizoma chuanxiong. According to the black plaster containing the far infrared ceramic powder and the preparation method of the black plaster containing the far infrared ceramic powder, the far infrared ceramic powder is added, so that the plaster has a disinfection function in actual use, and in addition, in the process of adding the minium, the fragrant oil is fried, so that the black plaster containing the far infrared ceramic powder has a good effect. Pharmacological components of the traditional Chinese medicinal materials can be better reflected in the plaster, the absorption effect of an actual product is improved, and the treatment effect on cervical spondylosis and lumbocrural pain of a patient can be improved.

The present application provides a kind of determination wine Jumu and ginkgo leaf content in Yining Tongmai Jian Nao Granules, adopts liquid chromatography to determine the content of monorin, strychnos seed, kaempferol, isorhamnetin, including being analyzed by liquid chromatograph, with the mixed solution of monorin control product, strychnos seed control product being prepared as a mixed control product solution, with the mixed solution of kaempferol control product, isorhamnetin control product being prepared as another mixed control product solution, with the solution of Yining Tongmai Jian Nao Granules sample being prepared as test product solution, corresponding chromatographic conditions are set respectively, are precisely sucked respectively, then are injected into liquid chromatograph respectively, and content is determined.The quality of Yining Tongmai Jian Nao Granules is evaluated by the detection of the present application by liquid chromatography, which can better reflect the internal quality of the compound granules and better control the quality of Yining Tongmai Jian Nao Granules.

The invention discloses a medicine composition for treating qi stagnation and blood stasis type closed fracture. The medicine composition is prepared from aspongopus, gaultheria yunnanensis, radix angelicae sinensis, sambucus williamsii, radix hedysari, actinidia chinensis root, root of sambucus chinensis, pseudo-ginseng, peach kernel, safflower, processed semen strychni, hematoxylon, native copper, akebiaquinata, fructus aurantii and rhizoma drynariae root. Aiming at the qi stagnation and blood stasis type closed fracture, the medicine composition with the effects of searching for toxins, removing qi, dissipating blood, stopping blockage, setting bones, promoting tissue regeneration and activating meridians to stop pain is adopted, both symptoms and root causes can be treated, the symptoms such as swelling and pain can be rapidly relieved, fracture healing can be promoted, local qi and blood circulation can be improved, and the recurrence risk can be reduced. The traditional Chinese medicine composition is suitable for qi stagnation and blood stasis type closed fracture patients, and is especially suitable for people needing overall conditioning and avoiding repeated attack.

The invention belongs to the technical field of traditional Chinese medicine, and discloses a formula and a preparation method of an external orthopedic plaster, the external orthopedic plaster comprises the following raw materials: scorpio, long-noded pit viper, radix clematidis, safflower, ground beetle, frankincense, myrrh, curcuma zedoary, lindera aggregata, lycopodium clavatum, garden balsam stem, angelica sinensis, eucommia ulmoides, ligusticum wallichii, semen strychni, borneol, camphor, dragon's blood, yellow lead, sesame oil, radix rehmanniae and radix rehmanniae preparata. Various medicinal materials are compatible with one another, both symptoms and root causes are treated according to etiology and pathogenesis of orthopedic diseases, and the traditional Chinese medicine composition has a remarkable curative effect on various orthopedic diseases such as traumatic injury, rheumatism ostalgia and hyperostosis; according to the preparation method, technological parameters such as soaking, frying and mixing are strictly controlled, so that effective components of the medicinal materials are fully extracted and converted, meanwhile, harmful substances are removed, irritation of the plaster to skin is reduced, and safety is improved; the plaster substrate is moderate in viscosity and easy to paste and uncover, and the hardness of the substrate is adjusted by seasons, so that the plaster can adapt to different environments and seasons, and practical application and operation are facilitated.

The invention provides a traditional Chinese medicine composition for treating vitiligo and a preparation method thereof, and relates to the technical field of preparation of traditional Chinese medicines for treating vitiligo. The traditional Chinese medicine composition is divided into an external composition and an internal composition, the external composition is prepared from nux vomica, cantharides, walnut skin, green persimmon, green fig, plant soot and red garlic according to a specific weight ratio, and the internal composition is prepared from rye, black beans, black sesame, polygonum multiflorum and fructus psoraleae according to a specific weight ratio. The external composition is fermented in a dark place and then decocted into paste, and the oral composition is fried and then ground into powder. Through the combination of external use and oral administration, the synergistic effect of the traditional Chinese medicinal materials is fully exerted, the leucoderma symptom of a leucoderma patient can be effectively improved, the medicinal materials are wide in source, the preparation process is simple, and the traditional Chinese medicine composition is suitable for being popularized and applied in clinical and daily treatment.

This invention relates to a swelling-reducing and analgesic spray, made from 22 pure Chinese medicinal herbs, including processed aconite and strychnos nux-vomica, and baijiu (Chinese white liquor). It is an external spray with the functions of dispelling wind, promoting blood circulation, removing blood stasis, reducing swelling, and relieving pain. The invention selects 22 medicinal herbs from the prescription, grinds them into coarse powder, and brews them using traditional methods. The powder is placed in a sealed glass or ceramic container, submerged in 60-proof baijiu, and then sealed for brewing. The 60-proof baijiu solvent combines the medicinal components extracted from both tinctures and aqueous solutions, resulting in a long soaking and brewing time. During the process, appropriate stirring ensures the full extraction of the effective components of the herbs. This spray is convenient and quick to use clinically, with rapid onset of action, good efficacy, and no side effects. It is an effective remedy for treating rheumatic pain and pain caused by injuries.

The invention provides a 4 '-O-glucose glycosyl transferase AcUGT87AZ3 protein in an aesculus chinensis triterpene synthesis pathway, an AcUGT87AZ3 gene and application of the AcUGT87AZ3 protein and the AcUGT87AZ3 gene, and belongs to the technical field of biology. The method is combined with transcriptome data analysis; the UGT gene capable of catalyzing the 4 '-O-glucose glycosylation of 3 beta-O-{beta-D-glucopyranoglucuronic acid}-protoaescin, geligillaceae saponin IC or 21 beta-O-tigillaceae acyl-22 alpha-O-acetyl-geligillaceae saponin IC is obtained through screening, and the UGT gene can be used for catalyzing the 4'-O-glucose glycosylation of the geligillaceae saponin IC. An escherichia coli in-vitro enzyme activity experiment and a tobacco transient expression system verify that the AcUGT87AZ3 can catalyze the synthesis of 3 beta-O-{[beta-D-glucopyranose-(1-4)]-beta-D-glucopyranuronic acid}-proaescin, aescin B and aescin A. The AcUGT87AZ3 can catalyze the synthesis of 3 beta-O-{[beta-D-glucopyranose-(1-4)]-beta-D-glucopyranuronic acid}-proaescin.

This is a traditional Chinese medicine fumigation and washing compound preparation for treating rheumatoid arthritis of the wind-cold obstruction type, belonging to the field of traditional Chinese medicine preparations for the treatment of rheumatoid arthritis. It is made from 10-25 parts of Morinda officinalis, 5-15 parts of Angelica sinensis (tail), 8-12 parts of raw licorice root, 5-12 parts of Schizonepeta tenuifolia, 5-15 parts of Atractylodes macrocephala, 8-15 parts of Clerodendrum trichotomum, 10-20 parts of Tripterygium wilfordii, 5-12 parts of Agkistrodon halys, 5-12 parts of Curcuma longa, 8-15 parts of Eucommia ulmoides powder, 8-15 parts of processed Strychnos nux-vomica, 8-15 parts of Caesalpinia sappan, and 5-15 parts of Cnidium monnieri. The traditional Chinese medicine fumigation and washing compound preparation proposed in this invention for treating rheumatoid arthritis of the wind-cold obstruction type is composed of Morinda officinalis, Angelica sinensis tail, raw licorice, Schizonepeta tenuifolia, Atractylodes macrocephala, Clerodendrum trichotomum, Tripterygium wilfordii, Agkistrodon halys, Curcuma longa, Eucommia ulmoides powder, processed Strychnos nux-vomica, Caesalpinia sappan, and Cnidium monnieri. Through heating, the effective components of the traditional Chinese medicine are extracted to achieve the effects of dispelling cold and dampness, and promoting blood circulation.

The invention discloses a traditional Chinese medicine composition for treating idiopathic facial paralysis, a paste rubbing agent and a preparation method, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 25 to 35 parts of processed semen strychni, 10 to 20 parts of caulis sinomenii, 10 to 20 parts of cassia twig, 8 to 15 parts of radix aconiti preparata, 8 to 15 parts of radix aconiti lateralis praeparata slice, 5 to 10 parts of croton, 5 to 10 parts of vinegar frankincense, 3 to 5 parts of loofah sponge and 3 to 5 parts of ground beeltle. The traditional Chinese medicine composition is reasonable in compatibility and rich in raw materials, the components are effectively combined, the whole formula has the effects of dispelling wind, resolving stagnation, relaxing tendons and relieving urgency, and the traditional Chinese medicine composition is effectively used for treating idiopathic facial paralysis, is convenient to use and good in effect, is an innovation of medicines for treating idiopathic facial paralysis, and has good popularization and application values and practical clinical significance.

The invention relates to an external traditional Chinese medicine ointment composition for treating lumbar disc herniation, which can effectively solve the problems of slow effect and limited effect of the existing medicine for treating lumbar disc herniation. The traditional Chinese medicine is prepared from frankincense, asarum, borneol, alangium platanifolium, radix aconiti kusnezoffii, herba chloranthi serrati, radix aconiti, short-pedicel aconite root, herba taxilli, kadsura longepedunculata, radix angelicae pubescentis, garden balsam stem, lycopodium clavatum, radix rehmanniae, prepared rehmannia root, radix dipsaci, safflower, rhizoma smilacis glabrae, cuttlebone, angelica sinensis, sappan wood, paris polyphylla, sea horse, semen momordicae, semen strychni, anisodus acutangulus, astragalus membranaceus, pseudo-ginseng, rhizoma drynariae, herba epimedii, obscured homalomena rhizome, eucommia ulmoides, kadsura pepper stem, acanthopanax, schizophragma integrifolium, the black plaster is prepared from bighead atractylodes rhizome, cinnamon, rhizoma atractylodis, codonopsis pilosula, poria cocos, gentiana macrophylla, hairyvein agrimony, radix sophorae flavescentis, fructus kochiae, common carpesium fruit, coptis chinensis, scutellaria baicalensis, golden cypress, rheum officinale, honeysuckle, radix clematidis, radix paeoniae rubra, long-noded pit viper, ground beetle, liquidambar formosana hance and bulbus fritillariae cirrhosae according to a conventional black method. The traditional Chinese medicine composition has the effects of activating blood, relieving pain, removing stasis and diminishing swelling.

The pain relieving liniment is prepared from the following raw materials in parts by weight: 5 to 15 parts of radix aconiti kusenzoffii, 5 to 15 parts of radix aconiti kusenzoffii, 5 to 20 parts of semen strychni, 4 to 13 parts of herba artemisiae rupestris, 5 to 18 parts of scorpio, 6 to 17 parts of centipede, 4 to 18 parts of long-noded pit viper, 5 to 19 parts of earthworm, 20 to 30 parts of ground beetle, 1 to 7 parts of rhizoma chuanxiong, 1 to 5 parts of radix achyranthis bidentatae and 1 to 5 parts of cortex eucommiae. The traditional Chinese medicine composition provided by the invention has the remarkable effects of dredging channels and collaterals, promoting qi to activate blood, relieving swelling and pain, dispelling wind and resolving dampness, warming yang and dispelling cold and inducing diuresis to alleviate edema, and is short in treatment course, quick in effect, high in curative effect, low in treatment cost, free of toxic and side effects and suitable for being widely applied to treatment of various diseases caused by channel obstruction and qi and blood stasis.

The invention discloses a dogwood flower extract with anti-oxidation and blood sugar and lipid reducing effects as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The invention aims to solve the technical problems of regulating blood sugar, insulin, blood fat and antioxidant level by activating a PI3K / AKT / mTOR pathway in vivo, improving liver, kidney and pancreas injuries and exerting anti-diabetic activity by reducing inflammatory factor expression. According to the key point of the technical scheme, the invention discloses a dogwood flower extract with the effects of resisting oxidation and reducing blood sugar and blood lipid. The active ingredients of the dogwood flower extract comprise morroniside, swertioside, loganin, ursolic acid, oleanolic acid, dogwood neoglycoside, gallic acid, protocatechuic acid, p-hydroxybenzoic acid, catechin, chlorogenic acid, caffeic acid, epicatechin, orientin, rutin, ferulic acid, benzoic acid, resveratrol, quercetin and cinnamic acid.

The invention discloses meridian activating stone needle warming and dredging medicinal oil and a preparation method thereof, the meridian activating stone needle warming and dredging medicinal oil comprises medicinal components and natural vegetable oil, and the ratio of the medicinal components to the natural vegetable oil is 1g: 1-5mL; the medicine components comprise the following components in parts by weight: 25-35 parts of processed semen strychni, 40-50 parts of flos carthami, 40-50 parts of ginger processed cortex magnoliae officinalis, 55-65 parts of bran-fried fructus aurantii immaturus, 25-35 parts of processed fructus evodiae, 85-95 parts of raw semen coicis, 25-35 parts of peach kernels, 25-35 parts of radix angelicae sinensis, 25-35 parts of cortex cinnamomi, 10-20 parts of herba ephedrae and 25-35 parts of rhizoma chuanxiong. The cure rate of an intervention group adopting the medicinal oil disclosed by the invention is 42.9%, the total effective rate is 100%, and after intervention, the clinical curative effect and gastrointestinal symptom score of a patient in a test group are obviously superior to those of a control group (Plt; therefore, the medicinal oil combined with stone needle therapy can relieve clinical symptoms of patients, reduce the score of gastrointestinal symptoms and improve the clinical curative effect.

The invention discloses a preparation method of an external traditional Chinese medicine liquid for treating synovitis osteoarthrosis, and relates to the technical field of external traditional Chinese medicine preparations, and the preparation method comprises the following steps: raw material pretreatment: taking zaocys dhumnade, radix aconiti preparata, radix aconiti kusnezoffii preparata, radix angelicae pubescentis, rhizoma pinelliae preparata, eucommia ulmoides, radix achyranthis bidentatae, salvia miltiorrhiza, safflower carthamus, lumbricus, centipede, herba portulacae, lycopodium clavatum, phryma leptostachya, semen strychni preparata, radix et rhizoma rhei preparata, borneol and mint; according to the formula disclosed by the invention, aiming at the core pathogenesis of wind-cold-dampness arthralgia and blood stasis blocking collaterals, insect medicines capable of strongly activating meridians to stop pain and medicinal materials such as aconite and semen strychni capable of expelling wind and removing cold are selected, and blood activating and transdermal components are combined, so that the pain can be quickly relieved, the joint function can be improved, and the curative effect is good. The radix aconiti, the radix aconiti agrestis, the semen strychni and the rhizoma pinelliae in the formula are processed products (processed), toxic components (such as aconitine and strychnine) of the radix aconiti, the radix aconiti agrestis, the semen strychni and the rhizoma pinelliae are partially converted or reduced in the processing process, and the medication safety is greatly improved on the premise of strictly controlling the external dosage and range.

The invention discloses a processing method for reducing toxicity of nux vomica, and belongs to the technical field of traditional Chinese medicine treatment. The method comprises the following steps: S1, decocting semen strychni in a liquorice decoction for 3-7 hours, and fishing out the semen strychni; s2, drying at the temperature of 80 DEG C or below until the temperature is 50-60% dry; and S3, preheating the corn popper to 150-250 DEG C, adding the nux vomica in the step S2, continuously heating until the barometer reaches 2-4 barometric pressures, releasing the pressure, taking out the nux vomica, cooling, and sealing and storing. The popcorn machine is used for processing the semen strychni, and the semen strychni can be uniformly heated and the temperature can be controlled through rotation, so that the purpose of processing is achieved; the inside of the popcorn machine is sealed, and the popcorn machine can reach a higher temperature through pressurization, so that toxic substances in the semen strychni can be further reduced. After processing, the content of strychnine is less than 1.5%, the content of strychnine is less than 1%, and the toxicity of semen strychni can be obviously reduced.

The invention belongs to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine composition for conditioning sub-health and a preparation method thereof. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 20-30 parts of eucommia ulmoides, 10-20 parts of dipsacus root, 10-20 parts of radix achyranthis bidentatae, 8-15 parts of frankincense processed with vinegar, 8-15 parts of myrrh processed with vinegar, 5-12 parts of asarum, 5-12 parts of ligusticum wallichii, 5-12 parts of radix angelicae, 5-12 parts of angelica sinensis, 3-5 parts of semen strychni, 5-15 parts of prepared kusnezoff monkshood root, 5-15 parts of radix aconiti preparata, 10-20 parts of radix clematidis, 5-12 parts of common fenugreek seed, 5-12 parts of cassia twig, 5-12 parts of rosin, 5-12 parts of vitex negundo, 5-12 parts of fructus evodiae and 5- 5-12 parts of notopterygium root and 5-12 parts of radix angelicae pubescentis; a multi-target mechanism is formed through cooperation of multiple medicinal materials, and the purposes of efficiently improving sub-health symptoms, effectively guaranteeing medication safety and improving the drug effect stability are achieved.

The invention discloses a gentiana rigescens stem and leaf fermented feed additive with anti-inflammatory and immunomodulatory effects, the optimal gentiana rigescens stem and leaf and lactobacillus plantarum fermentation catalysis process are screened out through an orthogonal process, a fermentation product is obtained, swertiamarin, caffeic acid and loganic acid with higher anti-inflammatory activity are newly generated, and the anti-inflammatory and immunomodulatory effects of the gentiana rigescens stem and leaf fermented feed additive are improved. And the content of active ingredients such as gentiopicroside is increased. By establishing a DSS-induced mouse ulcerative colitis model and determining related indexes, the feed additive can significantly improve mouse colitis symptoms, reduce DAI score, reduce weight loss, inhibit colon shortening and reduce expression of inflammatory factors IL-1beta and IL-6 through intragastric administration, and has significant anti-inflammatory and immunomodulatory effects. According to the invention, innovative application of non-medicinal parts of traditional Chinese medicinal materials in the field of feed can be promoted, efficient utilization of agricultural by-products is realized, and a wide application prospect is provided for sustainable development of green animal husbandry.

This invention relates to a traditional Chinese medicine composition comprising active ingredients extracted and purified from Artemisia annua, Lonicera japonica, and Gardenia jasminoides. The active ingredients include: neochlorogenic acid (≥2‰), chlorogenic acid (≥5‰), cryptochlorogenic acid (≥2‰), caffeic acid (≥0.07‰), isochlorogenic acid B (≥0.35‰), isochlorogenic acid A (≥0.17‰), isochlorogenic acid C (≥0.19‰), geniposide (≥5.97‰), strychnos nux-oxidase (≥0.07‰), geniposide (≥0.17‰), genipin (≥0.22‰), genipin gentiopicroside (≥0.76‰), and 7-hydroxyswert (≥2.44‰). The composition contains ≥10.3‰ total acid and ≥21.58‰ total glycosides. Based on the experimental content of this invention, traditional Chinese medicine compositions with specific active ingredient content characteristics were screened out, which have stable and excellent therapeutic effects. The above-mentioned active ingredient content characteristics can be used for the quality control of the traditional Chinese medicine composition, thereby ensuring the quality stability and reliable efficacy of the traditional Chinese medicine preparation.

This invention belongs to the field of antibacterial product technology, specifically relating to the application of strychnine essential oil and caraway essential oil in the preparation of an antibacterial agent against Staphylococcus aureus. In the antibacterial agent, the concentration ratio of strychnine essential oil to caraway essential oil is 38-63:9-28. The combination of caraway essential oil and strychnine essential oil in this ratio exhibits superior antibacterial effects against Staphylococcus aureus.

The invention provides a facial paralysis nerve and muscle effect plaster and a preparation method thereof, and belongs to the technical field of plasters. The nerve and muscle effect plaster for facial paralysis comprises a plaster medicament and a medicine carrying layer, wherein the plaster medicament comprises the following raw materials: raw stiff silkworm, centipede, scorpion, arisaema cum bile, divaricate saposhnikovia root, cassia twig, ligusticum wallichii, rhizoma typhonii, safflower, myrrh, asarum, semen strychni, borneol and vaseline; and the medicine carrying layer is a medical pressure-sensitive adhesive. The medicine carrying layer is of a claw-shaped structure and comprises one round bottom and four branches, facial nerves can be accurately covered, the directions of the four branch structures can be adjusted at will, lifting in the opposite direction is conducted according to the muscle sagging direction of facial paralysis, and the effect is improved.