Traditional Chinese medicine ointment for rapid bone setting and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine ointment for rapid bone setting. The traditional Chinese medicine ointment is prepared from the following raw materials in parts by weight: 1 to 10 parts of semen strychni, 1 to 20 parts of herba lycopodii, 1 to 7 parts of catechu, 1 to 10 parts of myrrh, 1 to 5 parts of dragon's blood, 1 to 20 parts of garden balsam stem, 1 to 5 parts of radix aconiti agrestis, 1 to 8 parts of indigo naturalis, 1 to 5 parts of rhizoma kaempferiae, 1 to 10 parts of borneol, 1 to 8 parts of radix aconiti, 1 to 15 parts of frankincense, 1 to 25 parts of radix saposhnikoviae, 1 to 18 parts of radix dipsaci, 1 to 15 parts of rhizoma smilacis glabrae, 10 to 25 parts of rhizoma drynariae, 1 to 10 parts of musk and 2 to 5 parts of achyranthes aspera. The raw materials are processed and prepared into mixed medicine powder, sesame oil and minium are taken, the mass ratio of the sesame oil to the minium to the mixed medicine powder is 1: 1: 1, firstly, the sesame oil is put into a container to be heated, then the obtained mixed medicine powder is added, after uniform stirring, decoction is conducted for 30 seconds, flameout is conducted for natural cooling, then minium is put into the container, uniform stirring is conducted again, and the mixture in the container is oxidized to be dark. The ointment is suitable for traumatic injury and fracture swelling and pain, and can accelerate fracture healing and relieve local pain and swelling when being externally applied.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine, and specifically refers to a traditional Chinese medicine ointment for rapid bone fracture healing and its preparation method. Background Art

[0002] Fracture, as a common traumatic disease, not only brings physical pain to patients, but also affects their daily life and work. Traditional fracture treatment methods mainly include surgical reduction, fixation and rehabilitation exercises, but the recovery process is usually long, and patients often suffer from pain, swelling and inconvenience.

[0003] In traditional Chinese medicine theory, fractures belong to the category of "injuring tendons and bones", and its treatment principles include promoting blood circulation to remove blood stasis, reconnecting fractured bones, and regulating qi and blood. Traditional Chinese medicine has a long history and rich experience in fracture treatment. Many Chinese herbal medicines such as Strychnos nux-vomica, Lycopodium clavatum, Drynaria fortunei, etc. have the effects of promoting bone healing and relieving pain.

[0004] However, existing traditional Chinese medicine bone fracture ointments still have deficiencies in the preparation process, drug ratio and curative effect. For example, the preparation process of some ointments is cumbersome and not easy for large-scale production; the drug ratio of some ointments is unreasonable, resulting in insignificant curative effects.

[0005] In view of the problems existing in the prior art, the present invention proposes a traditional Chinese medicine ointment for rapid bone fracture healing and its preparation method. Summary of the Invention

[0006] The technical problem to be solved by the present invention is to overcome the above-mentioned technical defects and provide a traditional Chinese medicine ointment for rapid bone fracture healing and its preparation method.

[0007] To solve the above technical problems, the technical solution provided by the present invention is a preparation method of a traditional Chinese medicine ointment for rapid bone fracture healing, including the following steps:

[0008] Step 1) Preparation of mixed medicinal powder:

[0009] Take 1-10 parts by weight of Strychnos nux-vomica, 1-20 parts by weight of Lycopodium clavatum, 1-7 parts by weight of Acacia catechu, 1-10 parts by weight of Myrrh, 1-5 parts by weight of Sanguis draxonis, 1-20 parts by weight of Speranskia tuberculata, 1-5 parts by weight of Aconitum kusnezoffii Reichb., 1-8 parts by weight of Indigo naturalis, 1-5 parts by weight of Kaempferia galanga L., 1-10 parts by weight of Borneol, 1-8 parts by weight of Aconitum carmichaelii Debx., 1-15 parts by weight of Olibanum, 1-25 parts by weight of Saposhnikovia divaricata (Turcz.) Schischk., 1-18 parts by weight of Dipsacus asperoides C. Y. Cheng & T. M. Ai, 1-15 parts by weight of Smilax glabra Roxb., 10-25 parts by weight of Drynaria fortunei, 1-10 parts by weight of Moschus, 2-5 parts by weight of Achyranthes aspera L. respectively, then dry them to a water content of less than 7%, then pulverize and sieve them, and finally mix the obtained substances evenly to obtain the mixed medicinal powder;

[0010] Step 2) Boiling of the ointment:

[0011] Take sesame oil and litharge. The mass ratio of sesame oil, litharge to the mixed medicinal powder is 1:1:1. First, put the sesame oil into a container and heat it, then add the obtained mixed medicinal powder into it. After stirring evenly, boil for 30 seconds, turn off the heat and let it cool naturally. Then put in the litharge and stir evenly again, so that the mixture in the container oxidizes to a dark color and cools naturally to room temperature to obtain the medicinal ointment.

[0012] Further, the drying temperature in step 1 is 45 - 55 °C.

[0013] Further, the sieve mesh in step 1 is 80 - 100 meshes.

[0014] Further, the heating temperature of the sesame oil in step 2 is 115 - 125 °C.

[0015] The second object of the present invention is to provide a traditional Chinese medicine medicinal ointment for rapid bone fracture healing prepared by the above preparation method.

[0016] The raw materials used in the present invention are as follows:

[0017] Strychnos nux-vomica: Bitter in taste and cold in nature, highly poisonous, can dredge collaterals to relieve pain, disperse stasis and reduce swelling, is a powerful and drastic ingredient in the formula, with a strong power to expel pathogenic factors.

[0018] Lycopodium clavatum L. and Speranskia tuberculata: Both can soothe tendons and activate collaterals, dispel wind and dampness, promote qi and blood circulation, and assist bone healing.

[0019] Acacia catechu, Myrrh, Sanguis draxonis, Olibanum: These four ingredients can promote blood circulation to remove blood stasis, reduce swelling and relieve pain, and are important drugs for treating traumatic injuries.

[0020] Aconitum kusnezoffii Reichb. and Aconitum carmichaelii Debx.: Pungent, hot and poisonous, can dispel wind and dampness, warm the channels and relieve pain, applicable to pain syndromes caused by cold congealing and blood stasis.

[0021] Indigo naturalis: Cold in nature and salty in taste, can clear heat and detoxify, cool blood and eliminate macules, and reconcile the hot-natured drugs in the formula.

[0022] Kaempferia galanga L. and Saposhnikovia divaricata (Turcz.) Schischk.: The former warms the middle-jiao to transform dampness, and the latter dispels wind and relieves the exterior. The combination of the two can not only disperse exogenous wind-cold, but also regulate qi and blood internally.

[0023] Dipsacus asperoides C. Y. Cheng & T. M. Ai, Smilax glabra Roxb., Drynaria fortunei (Kunze) J. Sm.: Dipsacus asperoides C. Y. Cheng & T. M. Ai can tonify the kidney and strengthen bones, Smilax glabra Roxb. can promote diuresis and detoxify, and Drynaria fortunei (Kunze) J. Sm. can tonify the kidney, promote blood circulation, and connect bones and tendons, jointly building the foundation for strengthening tendons and bones.

[0024] Moschus: Pungent, warm, fragrant and spreading, can open the orifices and restore consciousness, promote blood circulation and disperse stasis, and is the guiding drug in the formula to lead the drugs upward and penetrate to the affected area.

[0025] Achyranthes aspera L.: Promote blood circulation to remove blood stasis, lead blood downward, and also can clear heat and detoxify, reconcile the properties of drugs.

[0026] Borneol: Pungent and cool, can open the orifices and restore consciousness, clear heat and relieve pain, and can assist the drugs to penetrate through the skin and reach the affected area directly.

[0027] Zhang Dan: Topically, it can draw out toxins to promote granulation and generate flesh, and astringe to stop bleeding. Here, it is used perhaps for its effect of astringing to stop bleeding and promoting wound healing.

[0028] For the traditional Chinese medicine ointment provided by the present invention, Drynaria rhizome is used to tonify the kidney and strengthen bones, and relieve pain from injuries, being the main medicine for mending bones and sinews; Dipsacus asper is used to tonify the liver and kidney, strengthen tendons and bones, and mend fractures. The two together serve as the monarch drugs, leading the effects of mending bones and sinews, and strengthening tendons and bones;

[0029] Olibanum and Myrrh are used to activate blood circulation to relieve pain, disperse swelling and generate flesh; Dragon's blood is used to promote blood circulation to remove stasis, stop bleeding and generate flesh; Strychnos nux-vomica is used to disperse stasis and reduce swelling, dredge collaterals and relieve pain. The four together serve as the ministerial drugs, assisting the monarch drugs to promote blood circulation to remove stasis, disperse swelling and relieve pain, and promote fracture healing;

[0030] Among them, Lycopodium clavatum and Speranskia tuberculata are used to relax tendons and activate collaterals, dispel wind and dampness; Aconitum kusnezoffii and Aconitum carmichaelii are used to warm the channels and dispel cold, dispel wind and relieve pain; Saposhnikovia divaricata is used to dispel wind and relieve the exterior, dispel dampness and relieve pain; Smilax glabra is used to detoxify dampness, dredge joints; Achyranthes aspera is used to promote blood circulation to remove stasis, strengthen tendons and bones. All these drugs together serve as the adjuvant drugs, assisting the monarch and ministerial drugs to dispel wind and dampness, dredge collaterals and relieve pain, and relieve local swelling and pain after fracture;

[0031] Borneol and Moschus are used to resuscitate the mind with aroma, promote blood circulation through the channels, disperse swelling and relieve pain; Indigo Naturalis is used to clear heat and detoxify, cool blood and reduce swelling; Kaempferia galanga is used to promote qi circulation to relieve pain, warm the middle-jiao and dispel cold; Catechu is used to astringe to stop bleeding, disperse swelling and generate flesh. All these drugs together serve as the messenger drugs, guiding the drugs directly to the affected area, and enhancing the effects of the whole formula in dispersing swelling and relieving pain, and promoting blood circulation to remove stasis.

[0032] The advantages of the present invention compared with the prior art are as follows: For the traditional Chinese medicine ointment provided by the present invention, Drynaria rhizome and Dipsacus asper serve as the monarch drugs, Olibanum, Myrrh, Dragon's blood, and Strychnos nux-vomica serve as the ministerial drugs, Lycopodium clavatum, Speranskia tuberculata, Aconitum kusnezoffii, Aconitum carmichaelii, Saposhnikovia divaricata, Smilax glabra, and Achyranthes aspera serve as the adjuvant drugs, and Borneol, Moschus, Indigo Naturalis, Kaempferia galanga, and Catechu serve as the messenger drugs. The compatibility of monarch, ministerial, adjuvant, and messenger drugs is rigorous, and together they achieve the effects of mending bones and sinews, promoting blood circulation to remove stasis, and dispelling swelling and relieving pain. It is applicable to traumatic injuries and swelling and pain caused by fractures. Topically applied, it can effectively accelerate fracture healing and quickly relieve local pain and swelling. Detailed implementation mode

[0033] The following further elaborates on a traditional Chinese medicine ointment for rapid bone mending and its preparation method according to the present invention in conjunction with embodiments.

[0034] Embodiment 1

[0035] A traditional Chinese medicine ointment for rapid bone mending, its preparation method includes the following steps:

[0036] Preparation of mixed medicinal powder: Take 5 parts of Strychnos nux-vomica, 10 parts of Lycopodium clavatum, 3 parts of Catechu, 5 parts of Myrrh, 3 parts of Sanguis Draxonis, 10 parts of Herba Speranskiae tuberculatae, 3 parts of Aconitum kusnezoffii Reichb., 5 parts of Indigo Naturalis, 3 parts of Kaempferia galanga, 5 parts of Borneol, 5 parts of Aconitum carmichaelii Debx., 8 parts of Olibanum, 15 parts of Saposhnikovia divaricata, 10 parts of Dipsacus asperoides C. Y. Cheng et T. M. Ai, 10 parts of Smilax glabra Roxb., 15 parts of Drynaria fortunei (Kunze) J. Sm., 5 parts of Moschus, and 3 parts of Achyranthes aspera L. by weight. Dry the above raw materials at 50 °C until the water content is less than 7%, then pulverize and sieve through a 90-mesh sieve, and mix evenly to obtain the mixed medicinal powder.

[0037] Preparation of medicinal ointment: Take sesame oil and Zhangdan, where the mass ratio of sesame oil, Zhangdan to the mixed medicinal powder is 1:1:1. First, heat the sesame oil in a container, then add the obtained mixed medicinal powder into it. After stirring evenly, boil for 30 seconds and then turn off the fire for natural cooling. Then add Zhangdan and stir evenly again to oxidize the mixture in the container to a dark color, and naturally cool to room temperature to obtain the medicinal ointment.

[0038] Usage method: Change the medicinal ointment once a week and continue to use it for 2 - 4 weeks.

[0039] Example 2:

[0040] A traditional Chinese medicine ointment for rapid bone union, the preparation method of which includes the following steps:

[0041] Preparation of mixed medicinal powder: Take 8 parts of Strychnos nux-vomica, 15 parts of Lycopodium clavatum, 6 parts of Catechu, 8 parts of Myrrh, 4 parts of Sanguis Draxonis, 15 parts of Herba Speranskiae tuberculatae, 4 parts of Aconitum kusnezoffii Reichb., 7 parts of Indigo Naturalis, 4 parts of Kaempferia galanga, 8 parts of Borneol, 7 parts of Aconitum carmichaelii Debx., 12 parts of Olibanum, 20 parts of Saposhnikovia divaricata, 15 parts of Dipsacus asperoides C. Y. Cheng et T. M. Ai, 12 parts of Smilax glabra Roxb., 20 parts of Drynaria fortunei (Kunze) J. Sm., 8 parts of Moschus, and 4 parts of Achyranthes aspera L. by weight. Dry the above raw materials at 48 °C until the water content is less than 7%, then pulverize and sieve through an 85-mesh sieve, and mix evenly to obtain the mixed medicinal powder.

[0042] Preparation of medicinal ointment: Take sesame oil and Zhangdan, where the mass ratio of sesame oil, Zhangdan to the mixed medicinal powder is 1:1:1. First, heat the sesame oil in a container, then add the obtained mixed medicinal powder into it. After stirring evenly, boil for 30 seconds and then turn off the fire for natural cooling. Then add Zhangdan and stir evenly again to oxidize the mixture in the container to a dark color, and naturally cool to room temperature to obtain the medicinal ointment.

[0043] Usage method: Change the medicinal ointment once a week and continue to use it for 2 - 4 weeks.

[0044] Typical case of Example 3

[0045] Case 1: Jiao Mourong, from Wanxincun, Hedong District. In February 2025, due to a left hip injury, he was diagnosed with a left femoral neck base fracture. The patient came to seek medical treatment. After using the medicinal ointment prepared in Example 1, changing the medicinal ointment once a week, after using it for 4 weeks, the patient could turn over slightly independently, and the left injured thigh could be slowly lifted.

[0046] Case 2: Liu Mouqing, male. In December 2016, he was diagnosed with a fracture of the lower segment of the right tibia and fibula due to a bruise. He came for treatment in April 2017. After using the ointment prepared in Example 1, the ointment was changed once a week. After using it for 4 weeks, the patient could walk independently on the ground.

[0047] Case 3: Bai Mou. In November 2015, he fell off an electric bike and suffered a fracture of the right scapula. After using the ointment obtained in Example 2, the ointment was changed once a week. Combined with bone setting and acupuncture treatment, the patient recovered after using it for 4 weeks.

[0048] Case 4: Ms. Wei, from Dongli District, Tianjin. In 2014, she suffered a compression fracture of the first lumbar vertebra. She came for treatment upon introduction by a friend. After using the ointment obtained in Example 2, the ointment was changed once a week. She recovered after using it for 4 weeks.

[0049] The above describes the present invention and its implementation manners, and such description is not restrictive. Generally speaking, if those of ordinary skill in the art are inspired by it and, without departing from the gist of the present invention, design similar structural manners and embodiments to the technical solution without creative efforts, they shall fall within the protection scope of the present invention.

Claims

1. A method for preparing a Chinese medicine ointment for rapid bone setting, characterized in that: The following steps are involved: Step 1) Preparation of mixed powder: Take 1-10 parts of Strychnos nux vomica, 1-20 parts of Lycopodiella cuneata, 1-7 parts of catechu, 1-10 parts of myrrh, 1-5 parts of Sanguisorba officinalis, 1-20 parts of Radix Angelicae Pubescentis, 1-5 parts of Radix Aconiti Kusnezoffii, 1-8 parts of Indigo Naturalis, 1-5 parts of Kaempferia galanga, 1-10 parts of Borneolum Syntheticum, 1-8 parts of Aconiti Chuanwu, 1-15 parts of Olibanum, 1-25 parts of Saposhnikovia divaricata, 1-18 parts of Dipsacus asper, 1-15 parts of Smilax glabra, 10-25 parts of Drynariae Rhizoma, 1-10 parts of Musk, and 2-5 parts of Radix Cyathulae, and then dry them respectively until the water content is less than 7%, then grind and sieve, and finally mix the obtained products evenly to obtain a mixed powder; Step 2) Preparation of ointment: Take sesame oil and zhangdan, wherein the mass ratio of sesame oil, zhangdan and mixed medicinal powder is 1:1:1, first put the sesame oil into a container and heat it, then add the obtained mixed medicinal powder thereto, stir evenly, boil for 30 seconds, turn off the heat and cool naturally, then add zhangdan, stir evenly again, oxidize the mixture in the container to a dark color, and cool naturally to room temperature to obtain an ointment.

2. The preparation method according to claim 1, characterized in that: The drying temperature in step 1 is 45-55°C.

3. The preparation method according to claim 1, characterized in that: The mesh size of the sieve in step 1 is 80-100 meshes.

4. The preparation method according to claim 1, characterized in that: The heating temperature of the sesame oil in step 2 is 115-125°C.

5. A Chinese medicinal ointment for rapid bone setting prepared by the preparation method according to any one of claims 1 to 4.